-
effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-apbi-breast-cancer.pdf
August 01, 2022 - controlled trial; WBI=whole
breast irradiation. … ): 5-year results from a
multicentre, randomised, controlled, phase 3, non-inferiority trial. … controlled trial" or "controlled clinical trial" or "clinical trial").pt. or (controlled
or placebo … * or random* or trial*).ti. or ((control or controlled or group* or placebo* or random*)
adj10 trial … controlled trial; WBI=whole breast irradiation.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-2005_executive.pdf
January 01, 2005 - controlled trial comparing
medications with surgery found that approximately two-
thirds of surgically … The above conclusion was based on three recent
meta-analyses of randomized controlled trials
comparing … The above conclusion was based on one fair-
quality (Grade B) randomized controlled trial and
one poor-quality … Randomized controlled trials of laparoscopic
fundoplication versus PPIs with long-term
followup are needed … controlled trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol-amendment.pdf
May 02, 2025 - controlled trials
• Non-randomized studies of interventions
(experimental or observational) with … (RCTs) and comparative well-controlled non-randomized studies of interventions
(NRSIs) evaluating chemotherapy … controlled trial'/exp OR 'phase 3':ti,ab OR
'phase iii':ti,ab OR random*:ti,ab OR RCT:ti,ab)
13 ' … '/de
OR 'controlled clinical trial*':ti,ab OR 'prospective study'/de OR 'retrospective study'/de OR … (('non
randomized' OR nonrandomized) NEXT/1 (compar* OR control* OR trial* OR stud*)) OR ((cohort* OR
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/skin-cancer_research-protocol.pdf
August 10, 2016 - controlled trial. … The SINS trial: a randomised
controlled trial of excisional surgery
versus imiquimod 5% cream for nodular … Five-year follow-up of a
randomized, prospective trial of topical
methyl aminolevulinate photodynamic … /
OR Randomized controlled trial/
OR Randomization/
OR Single blind procedure/
OR Double blind procedure … ed controlled trial$.tw.
OR Rct.tw.
OR Random allocation.tw.
OR Randomly allocated.tw.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_disposition-comments.pdf
April 18, 2013 - Comparative effectiveness randomized
controlled clinical trials answer the questions
which drugs are … Differences in subject
characteristics in randomized
controlled clinical trials that
examined drugs … controlled clinical
trial). … Randomized controlled
clinical trials that examined
adverse effects of preventive
drugs in children … Randomized,
double‐blind, placebo‐controlled study to evaluate the
efficacy and safety of topiramate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/case-management-future_research.pdf
June 01, 2015 - controlled trial. … Design of a randomized
controlled trial. BMC Fam Prac. 2011;12:68.
PMID: 21729265.
26. … controlled trial. … controlled trial. … controlled trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_research-protocol.pdf
April 01, 2013 - For KQs 1, 2, and 4, we will include randomized trials only if the randomized treatment
allocation was … Risk of bias of randomized controlled studies
Item Comment
1. … #407 (PIVOT):
design and baseline results of a randomized
controlled trial comparing radical
prostatectomy … controlled trial/ or random allocation/ or double-blind method/ or single-
blind method/ or placebos … controlled trial[pt] OR controlled clinical trial[pt] OR randomized
controlled trials[mh] OR random
-
effectivehealthcare.ahrq.gov/sites/default/files/tnd-0855-170515.pdf
April 28, 2017 - controlled trial. … Controlled Trial. … HeLP-Diabetes: randomised controlled trial protocol.
BMC health services research. … controlled trial. … clinical trial[pt])) OR (randomized controlled
trial[pt])”
Other N=258
Clinicaltrials.gov
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0855-170515.pdf
April 28, 2017 - controlled trial. … Controlled Trial. … HeLP-Diabetes: randomised controlled trial protocol.
BMC health services research. … controlled trial. … clinical trial[pt])) OR (randomized controlled
trial[pt])”
Other N=258
Clinicaltrials.gov
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/prevent-hai-protocol.pdf
April 16, 2024 - controlled trials,
nonrandomized controlled studies
For secondary interest interventions (other
devices … controlled trial'/exp OR 'phase 3':ti,ab OR 'phase iii':ti,ab
OR random*:ti,ab OR RCT:ti,ab)
#16 … Observational/
Cohort Studies/
Non-randomized
Controlled Trials
'controlled clinical trial'/de … trial*':ti OR (('non randomized' OR
nonrandomized) NEXT/1 control*):ti OR ((cohort* OR
experimental … of primary interest
(SRs, RCTs, Non-
randomized controlled
studies)
#9 AND (#14 OR #15 OR #16)
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-outcomes-diabetes-rapid-research.pdf
November 01, 2024 - Controlled Trial. … A Randomized
Controlled Trial of the Effects of Non-
Surgical Periodontal Therapy on Cardiac
Function … controlled
trial. … Controlled
Trial. … controlled trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
August 22, 2008 - Additionally, randomized controlled trials will be assessed for randomization
technique and allocation … A multicenter, randomized, double-blind,
placebo-controlled trial to evaluate the metabolic and respiratory … controlled trial. … controlled trial.pt.
15. controlled clinical trial.pt.
16. randomized.ab.
17. placebo.ab.
18. drug … controlled trial.pt.
15. controlled clinical trial.pt.
16. randomized.ab.
17. placebo.ab.
18. drug
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/malnutrition-hospitalized-adults-protocol.pdf
October 19, 2020 - controlled trial'/de OR
'randomized controlled trial (topic)'/de OR
random*:ab,ti OR nct* OR [randomized … controlled
trial]/lim)
12 KQ2 Non-randomized
trials
#9 AND ('cohort analysis' OR 'comparative … study':ti,ab OR 'controlled trial':ti,ab OR
'double blind':ti,ab OR 'double blinded':ti,ab OR
longitudinal … controlled trial'/de OR
'randomized controlled trial (topic)'/de OR
random*:ab,ti OR nct* OR [randomized … controlled
trial]/lim)
16
16 Systematic Reviews #14 AND ([cochrane review]/lim OR [systematic
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/peripheral-artery-disease-treatment_research-protocol.pdf
January 31, 2013 - controlled trial. … A randomized controlled trial. J Vasc Surg
1997;26(4):551-7. PMID: 9357454
29. … controlled trial[pt] OR controlled clinical trial[pt] OR randomized[tiab] OR
randomised[tiab] OR randomization … controlled trial[pt] OR controlled clinical trial[pt] OR randomized[tiab] OR
randomised[tiab] OR randomization … controlled trial[pt] OR controlled clinical trial[pt] OR randomized[tiab] OR
randomised[tiab] OR randomization
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb_surveillance.pdf
July 06, 2015 - controlled or observational trial, not a comparison of
ACE inhibitor, ARB or their combination versus … controlled trial (RCT) or 1000 (observational study) patients,
or was not at least 6 months duration … controlled or observational trial,
not a comparison of ACE inhibitor, ARB or their combination versus … Disease) trial was the only placebo-
controlled trial available to evaluate major efficacy
outcomes … was the
only placebo-controlled trial
available to evaluate major efficacy
Possibly out of date
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/engaging-caregivers-rapid-review.pdf
April 01, 2024 - controlled trial. … A randomized controlled
clinical trial. … controlled trial. … The care transitions intervention: Results of
a randomized controlled trial. … A randomized controlled
clinical trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-monitoring-systems-protocol.pdf
July 01, 2023 - controlled trial;
vs = versus
Literature Searches
Our search strategy will focus on databases … Continuous monitoring in an inpatient medical-surgical unit: a
controlled clinical trial. … A randomized trial of real-time automated clinical deterioration alerts
sent to a rapid response team … A controlled trial of electronic automated advisory vital signs
monitoring in general hospital wards … controlled trial;
vs = versus
Literature Searches
Data Extraction
Risk of Bias Assessment
Data
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-presentation-format_research.pdf
January 01, 2019 - In 20 out of these 23 papers the recommendation was that more randomized controlled
trials are necessary … Overall, the frequency of recommending further randomized controlled trials was
significantly different … For example, if it is deemed that a randomized trial is important, one could do a
power analysis under … controlled trial
VOI Value of information
A-1
7BAppendix A. … Year Journal
20133502 Economic evaluation of the DiAMOND randomized trial: cost
and outcomes of 2
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_surveillance.pdf
August 01, 2012 - In a randomized,
controlled trial presented at a conference but not
yet published, the risk difference … Quality of life was
reported in one randomized, controlled trial and
two observational studies and … The single randomized,
controlled trial had too small of a sample size and
too short of a follow up … In a randomized, controlled
trial presented at a conference but not yet published,
the risk difference … The single randomized, controlled
trial had too small of a sample size and too short of a
followup
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-infertility_research.pdf
June 01, 2017 - Matching Studies
We matched randomized controlled trials (RCTs) identified in CT.gov with those identified … randomized trial. … , controlled trial. … PCOSMIC: a multi-centre randomized trial
in women with PolyCystic Ovary Syndrome
evaluating Metformin … controlled trial.