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Showing results for "randomized controlled trial".

1421. Methods Guide for Medical Test Reviews Chapter 7 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-grading_methods.pdf
      July 01, 2012 - In the uncommon circumstance in which a diagnostic test is studied in the context of a clinical trial … rarely done, the effect of tests on the clinical outcomes described above can be assessed directly with trial … In cases where trial evidence is available, methods of applying grading criteria such as GRADE should … measuring sensitivity and specificity sufficient to evaluate a diagnostic test, and when do we need a randomized … trial?

1422. AHRQ's Evidence-based Practice Center Division Annual Report 2022: Solving the Puzzle for Evidence-Based Decision Making (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-year-in-review-2022.pdf
      January 01, 2022 - Assessing Bias in Randomized and Non-Randomized Studies.

1423. CER 217 Disposition of Comments: Management of Infertility (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-217-management-of-infertility-comments.pdf
      May 14, 2019 - We have included the evidence from the FASTT trial which provides evidence on the impact of firstline … There are several randomized trials of varicocele repair vs IVF, as well as numerous meta-analyses. … Peer Reviewer #5 Results Page 98—in regards to the FASST trial—were the delivery costs different due … The other RCT included in this analysis (Morin-Papunen, 2012) wasn’t really a head-to-head trial of

1424. Disposition of Comments Report for Technical Brief 14 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-survivor-care-transition_disposition-comments.pdf
      March 18, 2014 - Randomized controlled trial of a clinic-based survivorship intervention following adjuvant therapy … within a clinic or whether clinics were randomized. … Some of the NR’s are confusing (e.g., in Table 1, does this mean there is no trial name? … Routine follow-up of breast cancer in primary care: a randomized trial BMJ 1996; 313:665-9. … Randomized trial of long-term follow-up of early-stage breast cancer: a comparison of family physician

1425. Arcia-notes-Teresa (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/arcia-presentation.pdf
      May 29, 2025 - It is a randomized control trial in which each group serves as the other group's control.

1426. Strategies to De-escalate Aggressive Behavior in Psychiatric Patients (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/aggression_disposition-comments.pdf
      July 14, 2016 - and implementation support that was used in applying the Six Core Strategies during the clinical trial … may be worth including in discussing the clinical and policy decision-making implications of this trial … That perspective dictates starting with randomized controlled trials or certain other study designs … (e.g., nonrandomized controlled studies) that come close to RCTs (all other things equal, such as

1427. Long COVID Models of Care (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-covid-protocol.pdf
      February 18, 2023 - COVID symptoms Patient satisfaction Harms -- Timing Any -- Study Design Systematic reviews Randomized … controlled trials Observational studies, including cohort studies, case control studies, and other

1428. Comparative Effectiveness Review Disposition of Comments Report: Anxiety in Children (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/disposition-of-comments-cer-192-anxiety-in-children.pdf
      August 31, 2017 - possible that this variability could be driving results, given the apparent "open door" policy toward trial … Results Later (pg 36, line 42) the reference is only for the follow-up phase but not the initial trial … We identified 7 publications based on the same CAMS trial. … For example, for the CAMS trial, we found 7 studies. … trials seem to be inadequate even though from the perspective of a clinician to have any pediatric trial

1429. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/pain-chronic_disposition-comments.pdf
      September 01, 2011 - The difficulty in conducting truly randomized controlled trials is acknowledged and double- blinding … systematic reviews search multiple databases (e.g., EMBASE, PsycINFO, Cochrane Central Register of Controlled

1430. Implementing Evidence-Based Screening and Counseling for Unhealthy Alcohol-Use With Epic-Based Electronic Health Record Tools: A Guide for Clinics and Health Systems Developed as Part of a Pilot Dissemination Project (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/implementation-package-unhealthy-alcohol-use-final.pdf
      September 01, 2018 - Preventive Services Task Force (USPSTF) included 23 randomized-controlled trials that examined counseling … A systemic review and meta-analysis of 23 randomized-controlled trials showed that behavioral counseling

1431. Integrating Health System Data With Systematic Reviews_Methods Research Report (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-research-report-integrating-health-system-data.pdf
      April 01, 2020 - The reviews examined a range of strategies including patient-controlled analgesia, psychosocial interventions … Blood pressure checks and diagnosing hypertension (BP-CHECK): Design and methods of a randomized controlled

1432. DARTNet Summary Report (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-ambulatory-therapeutics_research.pdf
      July 01, 2009 - This sharing is highly controlled, with clear definitions of just what is shared, who is allowed to … This ability will allow DARTNet to essentially create a controlled trial environment within the routine … Nonetheless, adding more Gateway databases does not materially slow the distributed query process, which is controlled … They are limited to the development of queries from a controlled interface. … and risk of cardiovascular events in patients with type 2 diabetes mellitus: a meta-analysis of randomized

1433. Research White Paper Registries in Accountable Care Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/accountable-care-registries-guide-3rd-ed-addendum-white-paper-2018-5.pdf
      January 01, 2018 - Attendance at Post-Emergency Department Follow-up Via Automated Text Message Appointment Reminders: A Randomized … Controlled Trial. … Influenza vaccine text message reminders for urban, low-income pregnant women: a randomized controlled … trial.

1434. Healthcare Delivery of Clinical Preventive Services for People with Disabilities (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/people-with-disabilities-protocol.pdf
      January 16, 2024 - Methodological Risk of Bias of Individual Studies Risk of bias (internal validity) is only assessed for controlled … We will assess controlled trials and observational studies (e.g., cohort studies, case- control studies … Controlled trials and observational studies will be assessed using established criteria consistent with

1435. PEPTIC ULCER #11 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1512.pdf
      December 01, 2015 - Effects of rifaximin on urgency, bloating, and abdominal pain in patients with IBS-D: a randomized … , controlled, repeat treatment study.

1436. medication-assisted-treatment-protocol-160224 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-use-disorder_research-protocol.pdf
      February 24, 2016 - and  fetal   health  outcomes   -­-­   Timing   Any   -­-­   Study  Design   Systematic  reviews   Randomized …  controlled  trials   Observational  studies,  including  cohort  studies,   case  control  studies,

1437. Cerebral-Palsy-Feeding Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cerebral-palsy-feeding_executive.pdf
      March 01, 2013 - EPC = Evidence-based Practice Center; RCT = randomized controlled trial study and in a small number … Consistent Direct NR Insufficient KQ = Key Question; NA = not applicable; NR = not reported; RCT = randomized … controlled trial; SOE = strength of evidence 15 The study focused on caregiver training related … Risk of bias versus quality assessment of randomised controlled trials: cross sectional study.

1438. EPC Systematic Review Protocol: Achieving Health Equity in Preventive Services: Systematic Evidence Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/health-equity-protocol.pdf
      January 01, 2020 - settings in the United States Study designs All KQs: Original research, including RCTs, nonrandomized controlled … groups Language English language Languages other than English Abbreviations: KQ=Key Question; RCT=randomized … controlled trial a Populations adversely affected by disparities include racial and ethnic minority … Risk of Bias of Individual Studies The risk of bias (quality or internal validity) of individual controlled

1439. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pregnancy_hi_impact.pdf
      January 01, 2012 - potential diffusion (e.g., in phase III trials for pharmaceuticals or biotechnologies or in phase II or a trial … properly evaluate this intervention’s impact on neurodevelopment, one research expert stated that randomized … control trials or other direct comparison controlled studies “seem unnecessary though payers will … The trial was stopped for efficacy of prenatal surgery after the recruitment of 183 of a planned 200 … A randomized trial of prenatal versus postnatal repair of myelomeningocele.

1440. Making Healthcare Safer IV: Summary of Findings, 2023-2024 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-1-year-final-report-updated-title_0.pdf
      May 01, 2024 - PubMed, Embase, and Cochrane Library for systematic reviews and primary studies (2010–2023) o 2 randomized … controlled trials (RCTs), 6 pre-post studies, 1 single-arm study • Evidence Summary o Interventions … for systematic reviews (2019–2023) and primary studies (2016–2023) o 14 reviews, 14 RCTs, 6 non-randomized … Findings From Previous MHS Reports • Despite lacking randomized trials, MHS II found strong evidence