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Showing results for "randomized controlled trial".

1401. Gout Dx protocol_140715-draft (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_research-protocol-2014.pdf
      January 01, 2014 - Randomized controlled trials as well as prospective cohort and case control studies that compare outcomes

1402. Disposition of Comments for CER 212 Nonsurgical Treatments for Urinary Incontinence in Women (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-212-urinary-incontinence-disposition-comments.pdf
      August 08, 2018 - Also, the ROSETTA trial detailing a comparison between BTX and SNM is glaringly absent (Amundsen CL … August 2018 29 Research Review Section Reviewer Comment Response incontinence in women: a randomized … clinical trial. … There are no randomized trials involving mirabegron and thus this drug could not be studied for efficacy … One trial included in the most recent Cochrane Library Review on the subject investigated RUSI.

1403. Observed Association Between Antidepressant Use and Pneumonia Risk Was Confounded by Comorbidity Measures (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-seniors-pneumonia_research.pdf
      May 01, 2008 - In conclusion, we performed a controlled epidemiologic study to follow up on a prior data-derived hypothesis

1404. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay_research-protocol.pdf
      May 02, 2011 - This search will be conducted in MEDLINE® and the Cochrane Central Register of Controlled Trials. … Database of Systematic Reviews <2005 to February 2011>, EBM Reviews - Cochrane Central Register of Controlled

1405. PowerPoint Presentation (ppt file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-strength-evidence.ppt
      June 01, 2012 - Trial evidence can directly assess the effect of tests on clinical outcomes (rarely done). … Trial evidence can directly assess the effect of diagnostic tests on clinical outcomes, but this is rarely … In the case where trial evidence is available, the application of grading criteria (such as those of … measuring sensitivity and specificity sufficient to evaluate a diagnostic test, and when do we need randomized … controlled trials or observational studies) Aggregate quality of the studies under consideration from

1406. PowerPoint Presentation (ppt file)
      effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-strength-evidence.ppt
      June 01, 2012 - Trial evidence can directly assess the effect of tests on clinical outcomes (rarely done). … Trial evidence can directly assess the effect of diagnostic tests on clinical outcomes, but this is rarely … In the case where trial evidence is available, the application of grading criteria (such as those of … measuring sensitivity and specificity sufficient to evaluate a diagnostic test, and when do we need randomized … controlled trials or observational studies) Aggregate quality of the studies under consideration from

1407. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear_disposition-comments.pdf
      October 05, 2010 - In lieu on an appendix, we have provided a reference to an example of a well-conducted randomized controlled … trial comparing operative versus nonoperative treatments, as well as references of guidelines for

1408. Wireless-Motility-Capsule Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_executive.pdf
      May 01, 2013 - We asked the manufacturer of WMC about any published or unpublished randomized controlled trials or

1409. Disposition of Comments Technical Brief 41: Evaluation of Mental Health Mobile Applications (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-health-mobile-apps-disposition-of-comments.pdf
      May 20, 2022 - For example, the evidence section asks whether a randomized trial showing efficacy exists but not whether … that randomized trial is of any quality. … For example, if the app being evaluated has a clinical trial, how close is the app being evaluated … to the app that was evaluated during the clinical trial? … Demanding that an app be identical to what was evaluated in a trial that may have taken place years

1410. Chicago-Area DEcIDE Center (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/off-label-use-research-priorities_research.pdf
      May 01, 2009 - The USP-DI assessment, however, is based on expert consensus, rather than clinical trial evidence. … review may subsequently include a range of analyses from retrospective database queries to prospective randomized … III Not Recommended A B C A B C DRUGDEX STRENGTH OF EVIDENCE A Good and/or consistent Randomized … Controlled Trials (RCTs) B Less adequate or inconsistent RCTs C Non-RCT evidence RESULTING … research step will be to conduct a series of meta- analyses to accumulate and assess past clinical trial

1411. Disposition of Comments Report for Whole-Body Vibration Therapy for Osteoporosis (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-vibration-therapy_disposition-comments.pdf
      November 15, 2011 - cited articles, in the draft technical brief, which was a systematic review and meta- analysis of randomized … controlled trials about whole-body vibration, concludes that “before recommendations can be made for … Factors that can be adjusted and tightly controlled for with this new technology include: frequency,

1412. Comparative Effectiveness Review Disposition of Comments Report (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/bundled-payments-quality-effects_disposition-comments.pdf
      August 24, 2012 - controlled trials of bundled payments ever published. … There was only one study randomized at the provider level, and we identified no studies of bundled … payment programs randomized at the patient level.” … trial (home health care agencies were randomized) of a prospective payment demonstration that studied … control trial) are naïve and inappropriate.

1413. Making Healthcare Safer IV Rapid Review: Supply Chain Disruption Monitoring Programs (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/monitoring-programs-rapid-research.pdf
      April 01, 2025 - commentaries, uncontrolled studies, case reports Abbreviations: ED = emergency department; RCT = randomized … controlled trial; SSI = surgical site infection. 2.2 Literature Searches A research librarian searched … for the primary reviewer to use the Cochrane Collaboration’s tool for assessing the risk of bias of randomized … controlled trials (RCTs) or the ROBINS-I tool for assessing the Risk Of Bias In Non-randomized Studies … vitro NOT vivo)) NOT (human* OR patient*)):ti) 8 #7 NOT (('book'/de OR 'case report'/de OR 'clinical trial

1414. Breastfeeding and Health Outcomes for Infants and Children (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-protocol-amendment.pdf
      February 03, 2025 - cohort and case-controld studies and studies with observational follow-up of health outcomes from randomized … or non-randomized clinical trials of breastfeeding support interventions All other designs, including … domains defined in the AHRQ Methods Guide49, 50 and using an adapted version of the Risk Of Bias In Non-randomized … Risk Of Bias In Non- randomized Studies - of Exposure (ROBINS-E). [2022 June 1].

1415. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/12_pregnancy_potential_high_impact_june_2012.pdf
      January 01, 2012 - The trial was stopped for efficacy of the prenatal surgery after recruitment of 183 of a planned 200 … properly evaluate this intervention’s impact on neurodevelopment, one research expert stated that randomized … control trials or other direct comparison controlled studies “seem unnecessary though payers will … The trial was stopped for efficacy of prenatal surgery after the recruitment of 183 of a planned 200 … A randomized trial of prenatal versus postnatal repair of myelomeningocele.

1416. Disposition of Comments_Systematic Review_Trauma Informed Care: A Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-informed-care-disposition-comments.pdf
      January 14, 2025 - additional review questions were needed to better address the variable contextual landscape in ways the randomized … whether enough organizational units are available for the randomization required for a gold- standard randomized … trial, and we agree with the recommendation that alternative study designs should be explored.

1417. Disposition of Comments: Technical Brief 37 Prevention, Diagnosis, and Management of Opioids, Opioid Misuse, and Opioid Use Disorder in Older Adults (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-37-opiod-use-adults-comments.pdf
      November 03, 2020 - More discussion of the relative importance of population based studies, clinical cohort studies, and randomized … single observational study except for one of the clinician education studies which was evaluated by a randomized … controlled trial. … ● Only 1 study was a randomized trial. … No trial for yoga, massage therapy, acupuncture or behavioral therapies has progressed beyond Phase

1418. Proposed Governance and Data Management Policy for the Systematic Review Data Repository (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/data-repository-reviews_white-paper.pdf
      September 01, 2012 - creation of the proposed repository, we convened a panel of technical advisors with expertise in trial

1419. Research White Paper_Outcome Measure Harmonization and Data Infrastructure for Patient-Centered Outcomes Research in Depression: Data Use and Governance Toolkit (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/outcomes-research-depression.pdf
      October 01, 2021 - the purposes of the literature review, sharing data referred to the sharing of registry, clinical trial … A Global, Neutral Platform for Sharing Trial Data. N Engl J Med. 2016;374(25):2411-3. 4. … Data sharing and reanalysis of randomized controlled trials in leading biomedical journals with a full

1420. Nonopioid Pharmacologic Treatments for Chronic Pain | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/nonopioid-chronic-pain/research