Results

Total Results: 1,519 records

Showing results for "randomized controlled trial".

1381. Crosscutting-Horizon-Scan-High-Impact-1506 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1506.pdf
      June 01, 2015 - A phase IV trial is ongoing for patients with tuberculosis. … No definitive marker-related adverse effects were reported.”2 Another report from a clinical trial … That undermines the statistical analysis of trial results and makes it difficult to determine the ‘ … complications in patients undergoing esophageal resection (PREPARE study): Study protocol for a randomized … controlled trial.

1382. PEPTIC ULCER #11 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pepticulcer_hi_impact.pdf
      January 01, 2012 - potential diffusion (e.g., in phase III trials for pharmaceuticals or biotechnologies or in phase II or a trial … not approved for any indication by the FDA or European Medicines Agency. 21,27 In results of a randomized … , double blind, placebo-controlled, phase III trial, investigators reported that 63% of patients (n … intravenous fluids was 5.2 liters per week from pretreatment baseline. 29 Nine subjects discontinued the trial … studies, and one of these experts thought teduglutide should be evaluated in an active comparator trial

1383. Disposition of Comments CER 219 Antipsychotics for the Prevention and Treatment of Delirium (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/delirium-disposition-comments.pdf
      September 03, 2019 - One RCT reported no statistically significant between- group difference in patients randomized to intervention … respectively, finding that 2 cases of suspected neuroleptic malignant syndrome occurred in patients randomized … no effect on length of stay in the intensive care unit for all patients at risk of delirium when randomized

1384. Colorectal-Cancer-Liver-Metastases-Therapies Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-liver-metastases-therapies_executive.pdf
      December 01, 2012 - controlled trial (RCT) data comparing local hepatic therapies31,32 contribute to uncertainty regarding … The gray literature was also searched, including in databases with regulatory information, clinical trial … controlled clinical trial evidence on the use of local hepatic therapies for the included indications … existing case series can aid in identifying additional factors that should be documented and potentially controlled … Phase III trial comparing protracted intravenous fluorouracil infusion alone or with yttrium-90 resin

1385. Data Points 15: Breast Cancer Diagnostic Workup: Prognostic factor testing among older women with ductal carcinoma in situ and early invasive breast cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/dcis-prognostic-tests_research.pdf
      August 22, 2012 - Randomized trials have evaluated the ben- efit of tamoxifen after BCS for DCIS.3 In the National Surgical … Adjuvant Breast and Bowel Project (NSAPB) B-24 trial, use of tamoxifen was associated with a modest … is studying the potential efficacy and role of postoperative trastuzumab for DCIS in a Phase III randomized … completely excised ductal carcinoma in situ of the breast in the UK, Australia, and New Zealand: randomised controlled … trial.

1386. Public-Reporting-Quality-Improvement Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/public-reporting-quality-improvement_research-protocol.pdf
      August 17, 2011 - Reviews (hereafter, Methods Guide). 21 Study designs will be classified according to type (e.g., randomized … trial, nonrandomized trial, observational study, etc.) as part of the data abstraction phase, and

1387. Renal-Function Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-function_executive.pdf
      August 01, 2014 - ACS.13 However, in the Clopidogrel in Unstable Angina to prevent Recurrent Events (CURE) clinical trial … following databases for primary studies: MEDLINE®, Embase®, and the Cochrane Central Register of Controlled … controlled trials (RCTs) or observational studies. … controlled trials and observational studies with a comparison group … trial.

1388. Breastfeeding and Health Outcomes for Infants and Children (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-protocol.pdf
      February 01, 2023 - cohort and case-controld studies and studies with observational follow-up of health outcomes from randomized … or non-randomized clinical trials of breastfeeding support interventions All other designs, including … domains defined in the AHRQ Methods Guide49, 50 and using an adapted version of the Risk Of Bias In Non-randomized … Risk Of Bias In Non- randomized Studies - of Exposure (ROBINS-E). [2022 June 1].

1389. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/musculoskeletal-complaints-tests-children_research-protocol.pdf
      September 29, 2010 - Source: www.effectivehealthcare.ahrq.gov Published Online: September 29, 2010 Central Register of Controlled … SLE, undiagnosed limb pain or index test results Design • Two or more participants • Diagnostic randomized … controlled trial: Studies randomly assigned participants into receiving either the test or the reference

1390. Methods Guide for Medical Test Reviews (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-metaanalysis_methods.pdf
      July 01, 2012 - Using the principles of randomized controlled trial design to guide test evaluation.

1391. S96 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/s96.pdf
      October 01, 2007 - socioeconomic status of the entire country than a more narrowly drawn sample chosen for a clinical trial

1392. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/12_pregnancy_potential_high_impact_2012-12-11.pdf
      January 01, 2012 - properly evaluate this intervention’s impact on neurodevelopment, one research expert stated that randomized … control trials or other direct comparison controlled studies “seem unnecessary though payers will

1393. Evidence Summary_Comparative Effectiveness Review No. 257: Schedule of Visits and Televisits for Routine Antenatal Care: A Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-257-antenatal-care-evidence-summary.pdf
      June 01, 2022 - Studies varied greatly in sample size (randomized controlled trials [RCTs]: 80-2692; nonrandomized comparative

1394. Disposition of Comments_Systematic Review_The Effect of Protein Intake on Health: A Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-protein-intake-disposition-comments.pdf
      November 22, 2024 - in Healthy Individuals Associated with Protein Intake above the US Recommended Daily Allowance in Randomized … Controlled Trials and Observational Studies.

1395. DEcIDE 33: Summary Variables in Observational Resesarch: Propensity Scores and Disease Risk Scores (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/observational-research-scores_research.pdf
      May 01, 2012 - This large sample size requirement means that answering the question through a randomized controlled … trial would be very expensive and need to include a very large patient population followed for some … confounding, by presenting a comparison of characteristics similar to a “Table 1” from a clinical trial … biostatistics: propensity score methods for bias reduction in the comparison of a treatment to a non- randomized … design versus the analysis of observational studies for causal effects: parallels with the design of randomized

1396. White Paper: Narratively Describing Effects of Interventions in Systematic Reviews (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/white-paper-roadmap-interventions.pdf
      November 01, 2020 - The roadmap will be undergoing trial use, and we will revisit and re-evaluate this document after receiving … Abbreviations: RCT = randomized controlled trial.

1397. Disposition of Comments Report for Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Tests for Evaluating Musculoskeletal Complaints in Children (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/musculoskeletal-complaints-tests-children_disposition-comments.pdf
      March 07, 2012 - HEp-2 FANA and compare that directly to ELISA and the newer multiplex assays in a large prospective trial … There is no reason to conduct prospective cohort studies or diagnostic randomized trials in children … Could you give a bit more detail on what a diagnostic randomised trial would assess? … It is unlikely such a trial would be conducted.

1398. Disposition of Comments for CER 163 Appropriate Antibiotics (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_disposition-comments.pdf
      January 27, 2016 - it is likely to be relevant but on the other hand we do have evidence from one large international trial … the CCRCT abbreviation with CENTRAL to refer to our search of the Cochrane Central Register of Controlled … Most studies can be randomized. 93. … We suggest including the citation when referencing a particular trial and outcome measure as “best … No, it is correct as stated that most studies can be randomized. 187.

1399. Outcome Measure Framework Design Document (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/registry-of-patient-registries_research-2014.pdf
      January 01, 2014 - ...............................................................................................10 Controlled … studies, but it is designed primarily for providing information about experimental studies, such as randomized … Controlled Process During the stakeholder meetings, participants provided examples of patient and … The OMF will need to use a controlled process for collecting new data and reviewing the data for completeness … OMF Inclusion and Exclusion Criteria Because the OMF will use a controlled process for collecting and

1400. Disposition of Comments Report for Relationship Between Use of Quality Measures and Improved Outcomes in Serious Mental Illness (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-outcomes_disposition-comments.pdf
      January 15, 2015 - both observational (i.e., retrospective electronic medical records, registries) and interventional randomized … I also agree that one needs to be sensible and practical in that randomized controlled trials will … Sunovion (Public Comment) Next Steps AHRQ recommends “the design and implementation of a randomized … controlled trial to test the effectiveness of a QM or set of QM relative to a meaningful and feasible … While a randomized clinical controlled trial design is considered high-rigor with respect to balancing