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Total Results: 1,524 records

Showing results for "randomized controlled trial".

1361. S58 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/s58.pdf
      October 01, 2007 - Whereas participants in randomized clinical trials (RCTs) of drugs sometimes fail to represent the full … tions who ultimately use them, Medicaid data include a broader population, not limited by clinical-trial

1362. Treatment of Dementia Among Community-Dwelling and Institutionalized Medicare Beneficiaries (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-databases-methods_research.pdf
      May 01, 2008 - and memantine, a N-methyl-D-aspartate (NMDA) inhibitor, are effective9, and at least one clinical trial … focus of pharmacological treatment. 11, 12 In a previous study, the authors13 reviewed 81 recent randomized … Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized … controlled trial. … A 24- week, randomized, double-blind study of donepezil in moderate to severe Alzheimer's disease.

1363. Crosscutting-Horizon-Scan-High-Impact-1512 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1512.pdf
      December 01, 2015 - A phase IV trial is ongoing for patients with tuberculosis. … No definitive marker-related adverse effects were reported.”2 Another report from a clinical trial … That undermines the statistical analysis of trial results and makes it difficult to determine the ‘ … complications in patients undergoing esophageal resection (PREPARE study): Study protocol for a randomized … controlled trial.

1364. Crosscutting-Horizon-Scan-High-Impact-1506 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1506.pdf
      June 01, 2015 - A phase IV trial is ongoing for patients with tuberculosis. … No definitive marker-related adverse effects were reported.”2 Another report from a clinical trial … That undermines the statistical analysis of trial results and makes it difficult to determine the ‘ … complications in patients undergoing esophageal resection (PREPARE study): Study protocol for a randomized … controlled trial.

1365. Breast-Abnormalities-Tests-Update Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-abnormalities-tests-update_research-protocol.pdf
      July 01, 2010 - Although it is possible to estimate diagnostic accuracy from a two-group trial, the results of such … Direction and impact of language bias in meta-analyses of controlled trials: empirical study. … A cohort study of summary reports of controlled trials. JAMA 1990;263:1401-5. 21. Neinstein LS.

1366. Wheeled Mobility (Wheelchair) Service Delivery (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/wheelchair-service_disposition-comments.pdf
      January 01, 2012 - In calling for randomized trials we are not recommending violating good clinical practice. … For example, the authors recommend violating good clinical practice by initiating more randomized trials … We recognize that not having a vast collection of controlled clinical trials is fairly typical in any … The fact that there have not been controlled clinical trials conducted represents an opportunity for … complex rehab technologies without a prescription is similar to purchasing a custom TLSO orthotic or controlled

1367. Horizon Scanning_Rapid Cost Analyses of Selected Potential High-Impact Intervention Reports (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-2015.pdf
      January 01, 2015 - needed to determine cost savings of 2-level TDR using Mobi-C compared with 2-level ACDF; however in a randomized … Nonetheless, development is continuing to identify and address the short-comings of the HTN-3 trial. … Controlled-Release Phentermine/ Topiramate (Qsymia) for Treatment of Obesity Controlled-release … It is a controlled-release pill that is intended to be taken once daily and in trials reportedly resulted … Drug- Sensitivity Testing of Mycobacterium tuberculosis Dx blood test $470,000 $470,000 Obesity Controlled-Release

1368. A Framework for Conceptualizing Evidence Needs of Health Systems (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/white-paper-framework-for-conceptualizing-evidence-needs_0.pdf
      December 01, 2017 - Commissioners, “will always struggle to apply systematic reviews and randomized controlled trials, because … • Provide guidance for action, even if evidence is less strong than ideal (e.g., case studies when controlled … In the single randomized trial identified, Dobbins 200944 found that showing tailored messages combined … The belief that evidence synthesis producers only consider randomized controlled trials conducted in … A randomized controlled trial evaluating the impact of knowledge translation and exchange strategies

1369. Disposition of Comments: Technical Brief No. 38_Automated Entry Patient Generated Health Data for Chronic Conditions: The Evidence on Health Outcomes (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-38-chronic-conditions-comments.pdf
      March 01, 2021 - This is because, even if the trial showed a device benefit, the decision maker could utilize that … This trial did find a benefit of PGHD on a surrogate outcome, but the trial was at high risk of bias … may be more helpful to the field to examine multicomponent interventions, providing they do modular randomized … controlled trial designs to tease apart specific effects. … Given the increasing importance of PGHD in care and trial paradigms, this report is timely.

1370. Cer-238-Cervical-Ripening-Appendix-E-2 (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-e-2.xlsx
      January 01, 2017 - . 11.84% (49/414) RR 1.10 (95% CI 0.76 to 1.58) NR Eligibility criteria changed halfway through the trial … . 12.86% (27/210) RR 1.05 (95% CI 0.64 to 1.71) NR Eligibility criteria changed halfway through the trial … 5.71% (4/70) vs. 5.77% (6/104) RR 0.99 (95% CI 0.29 to 3.38) Delivery within 24 hours from entry into trial … E2 PPHN persistent pulmonary hypertension of the newborn PROM premature rupture of membrane RCT randomized … controlled trial RR relative risk SCN special care nursery SD standard deviation SGA small for gestational

1371. Technical Brief Protocol_ 0369 Models of Survivorship Care_2-15-13_v14[1] (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-survivor-care-transition_research-protocol.pdf
      March 27, 2013 - • All care settings • Acute care inpatient Study design • Systematic reviews • Case reports • Randomized … controlled trials • Opinions • Nonrandomized controlled trials • Commentaries • Prospective and retrospective

1372. Disposition of Comments Report for Imaging Techniques for Treatment Evaluation for Metastatic Breast Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-imaging_disposition-comments.pdf
      October 01, 2014 - In particular, the authors offer specific study designs (such as randomized trials) to answer gaps identified … Few prospective evaluations of very small numbers, no randomized evaluations of PET, yet clearly an … of women with metastatic breast cancer, and we suggest that this information could be obtained by randomized

1373. Disruptive-Behavior-Disorders-Research-App-E (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-research-app-e.xlsx
      January 01, 2022 - Risk of bias assessment for randomized controlled trials Author, Year Randomization Adequate?

1374. Executive Summary_Systematic Review: Association of Digestible Carbohydrate Intake With Cardiovascular Disease, Type 2 Diabetes, Obesity, and Body Composition (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible-executive-summary.pdf
      March 01, 2025 - of Type 2 Diabetes, Growth, Size, and Body Composition Fifteen prospective cohort studies and two randomized … controlled trials were included. … A rigorous long-term prospective study in a controlled feeding environment would answer these questions

1375. Disposition of Comments for Screening for Glaucoma: Comparative Effectiveness (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_disposition-comments.pdf
      April 01, 2012 - If one assumes that treatment is effective, the trial would be successful by simply increasing the … Early Manifest Glaucoma Trial Design and Baseline Data. … Controlled Trials (RCTs), which is an extremely expensive study design for a disease of low prevalence … We have included the suggestion of a randomized controlled trial in the future research section Peer … controlled trial because one group would need to be screened and treated if needed and followed for

1376. Executive Summary_Comparative Effectiveness Review No. 271: Nonpharmacologic Treatments for Maternal Mental Health Conditions (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-271-mental-health-pregnant-executive-summary.pdf
      July 01, 2024 - Our searches targeted randomized controlled trials (RCTs) from January 1, 2000, to January 17, 2024.

1377. Nonopioid Pharmacologic Treatments for Chronic Pain | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/nonopioid-chronic-pain/research

1378. Interventions Targeting Sensory Challenges in Children With Autism Spectrum Disorders - An Update (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-interventions-disposition.pdf
      May 26, 2017 - 2017/ Published Online: May 26, 2017 8 TEP Reviewer #2 Methods I don't understand how randomized

1379. PEPTIC ULCER #11 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pepticulcer_hi_impact.pdf
      January 01, 2012 - potential diffusion (e.g., in phase III trials for pharmaceuticals or biotechnologies or in phase II or a trial … not approved for any indication by the FDA or European Medicines Agency. 21,27 In results of a randomized … , double blind, placebo-controlled, phase III trial, investigators reported that 63% of patients (n … intravenous fluids was 5.2 liters per week from pretreatment baseline. 29 Nine subjects discontinued the trial … studies, and one of these experts thought teduglutide should be evaluated in an active comparator trial

1380. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy_disposition-comments.pdf
      March 11, 2010 - March 11, 2010 13 Section Comment Response Methods Methods section not clear about when non-randomized … Randomized controlled trials rarely exist in the diagnostic literature and are often not as appropriate