-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-254-rural-telehealth-executive-summary.pdf
December 01, 2022 - is often difficult to attribute impact to telehealth because--
o Weaker study designs are common: randomized … controlled trials and cohort
studies were identified and accounted for 3/5 of the included studies,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccine-safety_executive.pdf
January 01, 2020 - The following study designs were included:
• Controlled clinical trial. … In women who became pregnant in
the 4 years following the trial, there was a significantly
higher rate … Literature search procedures were extensive; however,
some unpublished trial results may not have been … Odds ratios could be calculated
for each event reported in each trial and postlicensure
study and, … Tutorial in
biostatistics: the self-controlled case series method.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/lumbar-fusion-draft-report-appendix-d.xlsx
January 01, 2019 - Evidence tables for randomized controlled trials (RCTs) and nonrandomized studies of interventions (NRSIs … B
Neurological complications
OR 0.87 (95% CI 0.70 to 1.07)
Table 4 says the results were controlled … 40.7 (15.0)
Decompression + Fusion: 40.9 (14.5) NR NR NR NR NR
9290 2 Abdu, 2009 SPORT NRSI
Clinical trial … Evidence tables for randomized controlled trials (RCTs) and nonrandomized studies of interventions (NRSIs … controlled trial
RDQ Roland Morris Disability Questionnaire
RFA radiofrequency ablation
RR risk ratio
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_disposition-comments.pdf
April 01, 2012 - If one
assumes that treatment is effective, the trial would be
successful by simply increasing the … Early Manifest Glaucoma Trial Design
and Baseline Data. … Controlled Trials
(RCTs), which is an extremely expensive study design
for a disease of low prevalence … We have included the suggestion of a randomized
controlled trial in the future research section
Peer … controlled trial because
one group would need to be screened and treated if
needed and followed for
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-update_executive.pdf
August 01, 2016 - Data Sources
We searched MEDLINE®, Embase®, the Cochrane Central
Register of Controlled Trials, and … Nine randomized
controlled trials (RCTs) and 11 other comparative studies
compared treatment options … Patients and clinicians had to agree to the possibility of not
having PTRAS to be included in a trial … Only the CORAL (Cardiovascular Outcomes in
Renal Atherosclerotic Lesions) trial explicitly incorporated … Only one trial of PTRAS
versus medical therapy had a primary clinical outcome
(CORAL: composite cardiovascular
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-2015.pdf
January 01, 2015 - needed to determine cost savings of 2-level TDR using Mobi-C compared with 2-level
ACDF; however in a randomized … Nonetheless, development is continuing to identify and
address the short-comings of the HTN-3 trial. … Controlled-Release
Phentermine/
Topiramate (Qsymia)
for Treatment of
Obesity
Controlled-release … It is a controlled-release pill that is
intended to be taken once daily and in trials reportedly resulted … Drug-
Sensitivity Testing of Mycobacterium tuberculosis Dx blood test $470,000 $470,000
Obesity
Controlled-Release
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-research-app-e.xlsx
January 01, 2022 - Risk of bias assessment for randomized controlled trials
Author, Year Randomization Adequate?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/wheelchair-service_disposition-comments.pdf
January 01, 2012 - In calling for randomized trials we are not recommending
violating good clinical practice. … For example, the authors recommend violating good clinical
practice by initiating more randomized trials … We recognize that not having a
vast collection of controlled clinical trials is fairly typical in
any … The fact that
there have not been controlled clinical trials conducted
represents an opportunity for … complex rehab technologies
without a prescription is similar to purchasing a custom
TLSO orthotic or controlled
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effectivehealthcare.ahrq.gov/sites/default/files/s58.pdf
October 01, 2007 - Whereas participants in
randomized clinical trials (RCTs) of drugs sometimes fail to
represent the full … tions who ultimately use them, Medicaid data include a
broader population, not limited by clinical-trial
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-imaging_disposition-comments.pdf
October 01, 2014 - In particular, the authors offer specific
study designs (such as randomized trials) to answer gaps identified … Few prospective evaluations of very
small numbers, no randomized evaluations of PET, yet clearly an … of women with metastatic breast
cancer, and we suggest that this information could be
obtained by randomized
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible-executive-summary.pdf
March 01, 2025 - of Type 2 Diabetes, Growth,
Size, and Body Composition
Fifteen prospective cohort studies and two randomized … controlled trials were
included. … A rigorous long-term prospective study in a controlled feeding environment
would answer these questions
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-survivor-care-transition_research-protocol.pdf
March 27, 2013 - • All care settings • Acute care inpatient
Study design • Systematic reviews • Case reports
• Randomized … controlled trials • Opinions
• Nonrandomized controlled trials • Commentaries
• Prospective and retrospective
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy_disposition-comments.pdf
March 11, 2010 - March 11, 2010
13
Section Comment Response
Methods Methods section not clear about when non-randomized … Randomized controlled trials
rarely exist in the diagnostic literature and are often
not as appropriate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-abnormalities-tests-update_research-protocol.pdf
July 01, 2010 - Although it is possible to estimate diagnostic accuracy from a two-group trial, the
results of such … Direction and impact of language bias in
meta-analyses of controlled trials: empirical study. … A cohort study of summary reports of
controlled trials. JAMA 1990;263:1401-5.
21. Neinstein LS.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-271-mental-health-pregnant-executive-summary.pdf
July 01, 2024 - Our searches targeted randomized controlled trials (RCTs) from January 1, 2000, to
January 17, 2024.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-health-systems-guidelines-development.pdf
February 01, 2019 - trial. … Using a systematic review in clinical
decision making: a pilot parallel,
randomized controlled trial … A controlled before and
after study. … , non-inferiority trial. … Interviewees reported that evidence from randomized control trials, cohort studies and types of
evidence
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-review-production_white-paper.pdf
February 01, 2015 - type of studies included; for example, one used existing
reviews if possible, and another limited to controlled … controlled trials, and non-randomized controlled
trials. … The key message was “two systematic reviews, seven randomized controlled trials, and
three non-randomized … Summary of Abstracts on Short-Acting Intramuscular Olanzapine for Acute
Agitation concluded: “Three non-randomized … How
important are comprehensive literature
searches and the assessment of trial quality
in systematic
-
effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-38-chronic-conditions-comments.pdf
March 01, 2021 - This is because,
even if the trial showed a
device benefit, the
decision maker could
utilize that … This trial did
find a benefit of PGHD on
a surrogate outcome, but
the trial was at high risk
of bias … may be more helpful to the
field to examine multicomponent interventions, providing
they do modular randomized … controlled trial designs to
tease apart specific effects. … Given the increasing importance of PGHD in
care and trial paradigms, this report is timely.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/public-reporting-quality-improvement_disposition-comments.pdf
July 26, 2012 - complex
system environment), I question the appropriateness of criteria developed
for the evaluation of controlled … However, we did
not use criteria unique to randomized trials. … The only exception is the 1st criterion that asks if
randomization was adequate for randomized
trials … The language is from the AHRQ methods
guidance and is not meant to apply only to
randomized trials. … Limitations AHRQ acknowledges that there is limited evidence….The
review indicates a great need for more controlled
-
effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1506.pdf
June 01, 2015 - A phase IV trial is ongoing for patients with
tuberculosis. … No definitive marker-related adverse effects were reported.”2 Another report
from a clinical trial … That undermines the statistical analysis of trial results and
makes it difficult to determine the ‘ … complications in patients
undergoing esophageal resection (PREPARE
study): Study protocol for a randomized … controlled
trial.