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Showing results for "randomized controlled trial".

1341. Integrating Stakeholder Preferences in Comparative Effectiveness Research: Potential Uses of Multi-Criteria Decision Analysis Techniques (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/mcda_webinar_transcript2.pdf
      August 27, 2012 - systematic reviews or aiding investigators in selecting specific features of a study protocol for randomized … controlled trials or observational research. … Of course, you can use clinical evidence from clinical trial data so we can transform from large clinical … focus on this third type of patient-reported or self-reported data but this is data obtained from controlled

1342. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/phenylketonuria_research-protocol.pdf
      March 29, 2011 - 56% of patients responded to treatment, and responsiveness can only be determined by a therapeutic trial … women with PKU who are of childbearing age to reinforce social support and positive attitudes about a controlled … Publication languages English only Admissible evidence (study design and other criteria) Controlled … anticipate that the evidence garnered from the literature search described above will consist of small randomized … anticipate that the evidence garnered from the literature search described above will consist of small randomized

1343. Evidence-based Practice Center Technical Brief Protocol: Disparities and Barriers for Pediatric Cancer Survivorship Care (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/pediatric-cancer-survivorship-protocol.pdf
      June 01, 2020 - GQ 4: • Studies with concurrent (e.g., randomized controlled trial) or historic comparator (e.g., … Evaluations reported only in abbreviated format (e.g., in a conference abstract) with the exception of trial … Searches will use controlled vocabulary and text words as not to miss newer studies not indexed yet

1344. Technical Brief 13: Gene Expression Profiling for Predicting Outcomes in Stage II Colon Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_technical-brief.pdf
      December 01, 2012 - Food and Drug Administration Web site, Key Informants, clinical trial Web sites, and scan of the grey … • Ongoing clinical trials on the topic from clinicaltrials.gov and other clinical trial registries … Currently recruiting Samsung Medical Center, Seoul NCT01472601 RCT = Randomized controlled trial … At this 2012 ASCO Annual Meeting Salazar et al., presented a status report on the PARSC trial using … o Prospective, retrospective, or prospective-retrospective o Randomized trial, controlled trial, cohort

1345. Pharma-Nonpharma-Ptsd-2022-Update-App-G2-3 (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2022-update-app-g2-3.xlsx
      January 01, 2022 - RoB judgement 2.1) Were ppts aware of their assigned intervention during the trial? … carers and people delivering the interventions aware of participants' assigned intervention during the trial … masking carers or ppts) were there deviations from the intended intervention that arose because of the trial … substantial impact (on the result) of the failure to analyse participants in the group to which they were randomized … RoB judgement 3.1) Were data for this outcome available for all, or nearly all, participants randomized

1346. Version-3-Immunity-After-Covid-19-Appendix-Table-B-1 (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19-appendix-table-B-1.xlsx
      January 24, 2022 - Immune Response to SARS-CoV-2: Result From A Cohort of COVID-19 Cases in Wuhan, China China Prospective controlled … 2,044,257 person-trials) ""we pooled participants, or person-days, across all trials (stacking the person-trial-days … into a single data set) rather than applying a separate model for each trial followed by pooling all … Because participants were included in more than 1 trial, we used a robust variance estimator to adjust

1347. Evidence-based Practice Center Systematic Review Protocol: Management of High-Need, High-Cost Patients: A Realist and Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/mgmt-hnhc-patients-protocol.pdf
      November 07, 2019 - and 2: All study designs except reviews summarizing across original studies or interventions KQ 3: Randomized … controlled trials, cluster randomized trials, cohort studies, case-control studies, quasi-experimental … i.e., internal validity), we will use the ROBINS-139 tool for observational studies and the Cochrane randomized … controlled trial (RCT) tool40 for RCTs.

1348. Disposition of Comments for Pressure Ulcer Treatment Strategies: Comparative Effectiveness (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_disposition-comments.pdf
      May 08, 2013 - , controlled trials. … Second, prospective, randomized clinically controlled trials of nutrition supplementation are often … A pilot randomised controlled trial comparing reactive air and active alternating pressure mattresses … controlled trial. … controlled trial).

1349. Disposition of Comments for Technical Brief 28 MAT Models (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-use-disorder_disposition-comments.pdf
      December 06, 2016 - mechanism for expanding the definition of a qualified practitioner under section 303(g)(2) of the Controlled … Restrictions on prescribing controlled substances and other limitations on telemedicine can limit access … possible to detect an incremental benefit of ancillary treatments such as counseling when tested in randomized … Evidence on oral naltrexone for opioid use disorder is summarized on pg 26; as we noted, no trial was … the clinic settings were limited but based on provision of methadone it is highly likely that this trial

1350. Treatment of Dementia Among Community-Dwelling and Institutionalized Medicare Beneficiaries (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-databases-methods_research.pdf
      May 01, 2008 - and memantine, a N-methyl-D-aspartate (NMDA) inhibitor, are effective9, and at least one clinical trial … focus of pharmacological treatment. 11, 12 In a previous study, the authors13 reviewed 81 recent randomized … Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized … controlled trial. … A 24- week, randomized, double-blind study of donepezil in moderate to severe Alzheimer's disease.

1351. children-special-needs-transition-protocol-131003 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/children-special-needs-transition_research-protocol.pdf
      October 01, 2013 - Examples of sources of grey literature include the Internet, government Web sites, clinical trial databases … languages English only Admissible evidence (study design and other criteria) Admissible designs Randomized … controlled trials, including wait-list control, cohorts with comparison, pre-post cohort without comparison

1352. Safety of Vaccines Used for Routine Immunization in the United States (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccine-safety_executive.pdf
      January 01, 2020 - The following study designs were included: • Controlled clinical trial. … In women who became pregnant in the 4 years following the trial, there was a significantly higher rate … Literature search procedures were extensive; however, some unpublished trial results may not have been … Odds ratios could be calculated for each event reported in each trial and postlicensure study and, … Tutorial in biostatistics: the self-controlled case series method.

1353. Executive Summary_Comparative Effectiveness Review No. 254: Improving Rural Health Through Telehealth-Guided Provider-to-Provider Communication (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-254-rural-telehealth-executive-summary.pdf
      December 01, 2022 - is often difficult to attribute impact to telehealth because-- o Weaker study designs are common: randomized … controlled trials and cohort studies were identified and accounted for 3/5 of the included studies,

1354. A Framework for Conceptualizing Evidence Needs of Health Systems (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/white-paper-framework-for-conceptualizing-evidence-needs_0.pdf
      December 01, 2017 - Commissioners, “will always struggle to apply systematic reviews and randomized controlled trials, because … • Provide guidance for action, even if evidence is less strong than ideal (e.g., case studies when controlled … In the single randomized trial identified, Dobbins 200944 found that showing tailored messages combined … The belief that evidence synthesis producers only consider randomized controlled trials conducted in … A randomized controlled trial evaluating the impact of knowledge translation and exchange strategies

1355. Cer-238-Cervical-Ripening-Appendix-E-2 (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-e-2.xlsx
      January 01, 2017 - . 11.84% (49/414) RR 1.10 (95% CI 0.76 to 1.58) NR Eligibility criteria changed halfway through the trial … . 12.86% (27/210) RR 1.05 (95% CI 0.64 to 1.71) NR Eligibility criteria changed halfway through the trial … 5.71% (4/70) vs. 5.77% (6/104) RR 0.99 (95% CI 0.29 to 3.38) Delivery within 24 hours from entry into trial … E2 PPHN persistent pulmonary hypertension of the newborn PROM premature rupture of membrane RCT randomized … controlled trial RR relative risk SCN special care nursery SD standard deviation SGA small for gestational

1356. User Engagement, Training, and Support for Conducting N-of-1 Trials (Chapter 6) | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/n-1-trials/research

1357. Disposition of Comments for CER 178 Newer Medications for Lower Urinary Tract Symptoms (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/prostatic-hyperplasia-medications_disposition-comments.pdf
      May 26, 2016 - showed a difference between silodosin and tamsulosin, it was a silodosin, 8 mg vs. tamsulosin, 0.2 mg. trial … introduction section: “Anticholinergics have been used more frequently for LUTS/BPH since the TIMES trial … We described AUR as it was described in the original trial. … We added References Peer Reviewer #3 Results -p. 21, line 7- when discussing Kaplan trial, add some … their efficacy with ED (participants could likely accurately predict which treatment group they were randomized

1358. Disposition of Comments for Screening for Glaucoma: Comparative Effectiveness (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_disposition-comments.pdf
      April 01, 2012 - If one assumes that treatment is effective, the trial would be successful by simply increasing the … Early Manifest Glaucoma Trial Design and Baseline Data. … Controlled Trials (RCTs), which is an extremely expensive study design for a disease of low prevalence … We have included the suggestion of a randomized controlled trial in the future research section Peer … controlled trial because one group would need to be screened and treated if needed and followed for

1359. Renal Artery Stenosis Management Strategies: An Updated Comparative Effectiveness Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-update_executive.pdf
      August 01, 2016 - Data Sources We searched MEDLINE®, Embase®, the Cochrane Central Register of Controlled Trials, and … Nine randomized controlled trials (RCTs) and 11 other comparative studies compared treatment options … Patients and clinicians had to agree to the possibility of not having PTRAS to be included in a trial … Only the CORAL (Cardiovascular Outcomes in Renal Atherosclerotic Lesions) trial explicitly incorporated … Only one trial of PTRAS versus medical therapy had a primary clinical outcome (CORAL: composite cardiovascular

1360. Horizon Scanning_Rapid Cost Analyses of Selected Potential High-Impact Intervention Reports (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-2015.pdf
      January 01, 2015 - needed to determine cost savings of 2-level TDR using Mobi-C compared with 2-level ACDF; however in a randomized … Nonetheless, development is continuing to identify and address the short-comings of the HTN-3 trial. … Controlled-Release Phentermine/ Topiramate (Qsymia) for Treatment of Obesity Controlled-release … It is a controlled-release pill that is intended to be taken once daily and in trials reportedly resulted … Drug- Sensitivity Testing of Mycobacterium tuberculosis Dx blood test $470,000 $470,000 Obesity Controlled-Release