-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antenatal-care.pdf
January 01, 2020 - of different interventions), including parallel design, pre-post
studies, and other comparisons
o Randomized … of different interventions), including parallel design, pre-post
studies, and other comparisons
o Randomized … Quantitative studies (KQ 1 & 2)
For randomized controlled trials (RCTs), including cluster randomized
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis_research-protocol.pdf
June 06, 2011 - NITs listed in KQ 1
Human subjects; adults (age ≥18 years of age)
English-language articles
Randomized … controlled trials, prospective and retrospective observational
studies, or registries
Study includes … Randomized controlled trials will be graded as
good, fair, or poor.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-pancreas_research-protocol.pdf
August 09, 2013 - We will search the
following databases using controlled vocabulary and text words: EMBASE®, MEDLINE® … Thus, if the studies had controlled for the confounders, the
effect would have been even larger. … A cohort study of summary reports of controlled
trials. JAMA. 1990 Mar 9;263(10):1401-5. … Direction and impact of language bias in meta-analyses
of controlled trials: empirical study. … For non-randomized trials, did the study employ any other methods to enhance group
comparability?
-
effectivehealthcare.ahrq.gov/sites/default/files/transcript_deliberativemethodswebinar.pdf
April 19, 2012 - in 2010, and the community
formed a project around public deliberation as an
experiment that’s a randomized … controlled trial comparing
five distinct deliberative methods to each other to a
control of education
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests_appendixes.pdf
May 23, 2005 - [mh]
Random*[ti]
Random allocation[mh]
Randomized controlled trial[pt]
Randomized controlled trials … controlled trials[mh] OR random allocation[mh] OR
randomized controlled trial[pt] OR double-blind method … Unacceptably
WeakStrong
Yes No
1 Mega-
Trial? … Unacceptably
WeakModerate
Yes No
1 Mega-
Trial? … Unacceptably
WeakWeak
Yes No
1 Mega-
Trial?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-update_executive.pdf
August 01, 2014 - language English only
Admissible evidence
(study design and other criteria)
Admissible designs
Randomized … controlled trials, prospective and retrospective cohort studies, and nonrandomized
controlled trials … new studies described in this
update to add to the conclusions of the original report
comprise 48 randomized … controlled trials (RCTs) and 17
nonrandomized trials or cohort studies. … Play-/Interaction-Focused Studies
Since our previous review, more studies of well-controlled
joint
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/wireless-motility-capsule_research-protocol.pdf
March 14, 2012 - • We will include all types of studies (e.g., randomized controlled trials, cohort studies, case … We will include all types of studies (e.g., randomized controlled trials, cohort studies, case series
-
effectivehealthcare.ahrq.gov/sites/default/files/topic-refinement.ppt
March 01, 2010 - Some beliefs will be based on long-term randomized controlled trials; others will be based on dogma,
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adults-trauma-interventions_research-protocol.pdf
November 08, 2012 - design and
other criteria)
Original research
For KQs 1 through 4 eligible study designs include:
• Randomized … controlled trials … on harms, additional eligible study designs are:
• Retrospective controlled cohort studies
• Case … Pharmacotherapy to prevent PTSD:
Results from a randomized controlled proof-of-concept trial in physically … Randomized, double-blind comparison
of sertraline and placebo for posttraumatic stress disorder in a
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-treatment-adherence_disposition-comments.pdf
December 20, 2012 - Several good cohort studies exist at this
point, but they have not been tested in clinical trial designs … controlled trial (RCT). … I think that
separate randomized trials would likely have to address
system-level and regimen-related … This approach has been shown
to improve adherence in randomized, controlled trials
evaluating managed … Just about every clinical trial currently has a
component that evaluates adherence, yet adherence is
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
September 29, 2014 - Is it not correct, however, that such a
selection and trial process is recommended by current clinical … Because potential confounders
were better controlled? … One comment: Long-term randomized controlled trials are challenging for the reasons
stated, but they … I think it is also important to briefly mention
clinical trial designs (e.g., pragmatic trials) that … could be useful in addressing
challenges of conventional “efficacy” trial design.
-
effectivehealthcare.ahrq.gov/sites/default/files/adhd_disposition-comments.pdf
October 01, 2011 - The Lilly sponsored comparative effectiveness trial
published by Newcorn and Michaelson had important … L.E.Arnold): A
randomized controlled crossover trial of methylphenidate in pervasive
developmental … Although
the MTA did not use a placebo after the first month, it did have
randomized treatment for … A 14-Month randomized clinical trial of
treatment strategies for attention-deficit/hyperactivity disorder … Randomized,
placebo-controlled, crossover study of methylphenidate for attention-
deficit/hyperactivity
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hemophilia-dental-rapid-response.pdf
July 01, 2024 - research librarian developed a comprehensive search strategy to search PubMed® and
Embase® for SRs, randomized … controlled trials (RCTs), controlled observational studies, and clinical
practice guidelines. … Disease Control and Prevention, National Institutes of Health, World Health Organization); clinical trial … controlled trials and practice guidelines. … controlled trial
SME Subject matter expert
SR Systematic Review
UKHCDO United Kingdom Haemophilia
-
effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1512.pdf
January 28, 2016 - In another phase III trial, patients with chronic HCV genotype 1,
2, 3, or 4 and HIV-1 coinfection … STRIVE (Sierra Leone Trial to Introduce a
Vaccine Against Ebola). … Ebola vaccine ring
vaccination trial in Guinea. [database online]. … treatment-naive cirrhotic and noncirrhotic
patients with chronic HCV genotype 1, 4, or 6
infection: a randomized … trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-knee-physical-therapy_disposition-comments.pdf
November 06, 2012 - To
address such complexity, our review focused on
randomized trials since these equally distribute … Randomized trials are gold standard in establishing
benefits with health care interventions. … We did include the article “Tai Chi Is Effective In
Treating Knee Osteoarthritis: A Randomized
Controlled … Trial. by Wang C, Schmid CH, Hibberd
PL, et al. … In addition, the comparison in this trial
was Tai Chi vs. stretching exercise.
-
effectivehealthcare.ahrq.gov/sites/default/files/technical-brief-34-health-worker-certification-comments.pdf
March 27, 2020 - Public Reviewer #4
(Molly Martin,
University of Illinois
at Chicago)
Discussion I cannot imagine a randomized … controlled trial that would compare under-
trained to fully-trained CHWs.
-
effectivehealthcare.ahrq.gov/sites/default/files/renal-cancer_executive.pdf
February 01, 2016 - We used the Cochrane Collaboration’s tool for assessing
the risk of bias of randomized controlled trials … controlled trial;
SGA = second-generation antidepressant; SR = systematic review
aSGAs approved for … studies (randomized controlled
trials, nonrandomized controlled trials, and
comparative cohort studies … The single randomized study was determined to
have an unclear risk of bias for both overall survival … A trial
comparing thermal ablation to partial nephrectomy would
be informative.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-245-breast-reconstruction-after-mastectomy-evidence-summary-updated-1.pdf
October 01, 2021 - These included 8
randomized controlled trials (N = 570 patients), 83 nonrandomized comparative studies
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pelvic-pain_research-protocol.pdf
February 16, 2011 - treating CPP or underlying
conditions such as endometriosis, dysmenorrhea, or adenomyosis; however, few randomized … controlled trials (RCTs) have evaluated those interventions. … English only
Admissible evidence (study
design and other criteria)
Admissible designs
• Controlled
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-243-prehospital-airway-management-evidence-summary_0.pdf
June 01, 2021 - o Future research should:
Focus on rigorous studies, preferably randomized controlled trials
(RCTs