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Total Results: 1,519 records

Showing results for "randomized controlled trial".

1281. Executive Summary: Radiation Therapy for Metastatic Bone Disease: Effectiveness and Harms (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-summary.pdf
      August 01, 2023 - Results We included 53 mostly fair-quality randomized controlled trials (RCTs) and 31 mostly fair-quality

1282. Stakeholder-Engagement-Benefits White-Paper (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholder-engagement-benefits_white-paper.pdf
      March 01, 2014 - controlled trial(s); s/h=stakeholder(s); SR=systematic review(s); UK=United Kingdom; INVOLVE definition … controlled trial(s); s/h=stakeholder(s); SR=systematic review(s); UK=United Kingdom; INVOLVE definition … controlled trial(s); s/h=stakeholder(s); SR=systematic review(s); UK=United Kingdom; INVOLVE definition … controlled trial(s); s/h=stakeholder(s); SR=systematic review(s); UK=United Kingdom; INVOLVE definition … controlled trial(s); s/h=stakeholder(s); SR=systematic review(s); UK=United Kingdom; INVOLVE definition

1283. Disposition of Comments Report for Imaging Techniques for the Diagnosis and Staging of Hepatocellular Carcinoma (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_disposition-comments.pdf
      October 23, 2014 - We revised the Discussion to state: “The trial primarily enrolled patients with HBV infection, who are … Given the lack of high quality randomized data to support screening/surveillance for HCC in high risk … trial of screening versus no screening is impractical because screening has become standard of care … The authors do state that a trial comparing different imaging techniques might be feasible. … We searched for ongoing RCT’s of surveillance through searches on clinical trial registries but found

1284. Disposition of Comments Report for Primary Care Management of Abnormal Uterine Bleeding (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_disposition-comments.pdf
      March 21, 2013 - Peer reviewer #5 Executive Summary ES-10 l.19 Placebo controlled studies have failed to find any increase … The search did not identify randomized clinical trials of cyclic progestins of fair or good quality … We have modified the summary to indicate there are no “controlled” longer term follow-up studies. … They were able to reduce the total number of studies to a relatively few randomized clinical trials, … This is why we report the proportion of trial arms that discontinued study drug.

1285. Effectiveness of Early Diagnosis, Prevention, and Treatment of Clostridium difficile Infection (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_disposition-comments.pdf
      March 01, 2012 - Peer Reviewer #6 Executive Summary Page 5, Treatment: I believe there was one clinical trial comparing … This key question was interested in treatments or therapies under investigation, whether through controlled … Additionally, we analyze the data using a strict intention-to- treat analysis, where all randomized … Peer Reviewer #5 Results Pages 91 and 95: Surawicz articles, all patients enrolled in this trial … The FDA is now realizing that in their clinical trial requirements.

1286. Research Protocol: Characteristics of Existing Asthma Self-Management Education Packages (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-education-protocol.pdf
      January 01, 2018 - recent review of reviews3 synthesized the findings of twenty-seven systematic reviews encompassing 270 randomized … controlled trials (RCTs) of AS-ME packages. … We will search the following databases using controlled vocabulary and text words: MEDLINE, PubMed

1287. Disposition of Comments: Comparative Effectiveness Review No. 232_Interventions for Breathlessness in Patients With Advanced Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/cer-232-breathlessness-cancer-comments.pdf
      November 19, 2020 - Respir Med. 2014 Dec;2(12):979-87 https://www.ncbi.nlm.nih.gov/pubmed/25465642 included 105 patients randomized … I could see including combination intervention studies if controlled by changing one aspect. … Page 24, HRQoL, first paragraph: sentence 'The trial found no statistically significant difference in … effects of morphine on dyspnea and ventilatory function in elderly patients with advanced cancer: A randomized … double blind controlled trial .

1288. Layout 1 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-executive.pdf
      December 01, 2009 - Medical personnel usually want to see the results of at least one randomized controlled trial demonstrating … Given the currently available alternatives, there is no need to conduct randomized controlled trials … will be beneficial, and therefore it is acceptable to study the intervention in a clinical research trial

1289. Effectiveness of Noninvasive Diagnostic Tests for Breast Abnormalities Appendices (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests_appendixes.pdf
      May 23, 2005 - [mh] Random*[ti] Random allocation[mh] Randomized controlled trial[pt] Randomized controlled trials … controlled trials[mh] OR random allocation[mh] OR randomized controlled trial[pt] OR double-blind method … Unacceptably WeakStrong Yes No 1 Mega- Trial? … Unacceptably WeakModerate Yes No 1 Mega- Trial? … Unacceptably WeakWeak Yes No 1 Mega- Trial?

1290. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis_research-protocol.pdf
      June 06, 2011 - NITs listed in KQ 1 Human subjects; adults (age ≥18 years of age) English-language articles Randomized … controlled trials, prospective and retrospective observational studies, or registries Study includes … Randomized controlled trials will be graded as good, fair, or poor.

1291. Protocol: Imaging for Pretreatment Staging of Small Cell Lung Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-staging_research-protocol.pdf
      December 08, 2014 - We will search the following databases using controlled vocabulary and text words: EMBASE, MEDLINE, … Thus, if the studies had controlled for the confounders, the effect would have been even larger. … publication and study type #25 AND ('clinical article'/exp OR 'clinical article' OR 'clinical trial … '/exp OR 'clinical trial' OR 'controlled study'/exp OR 'controlled study' OR 'intermethod comparison … For non-randomized trials, did the study employ any other methods to enhance group comparability?

1292. Schedule of Visits and Use of Telemedicine for Routine Antenatal Care: A Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/antenatal-care.pdf
      January 01, 2020 - of different interventions), including parallel design, pre-post studies, and other comparisons o Randomized … of different interventions), including parallel design, pre-post studies, and other comparisons o Randomized … Quantitative studies (KQ 1 & 2) For randomized controlled trials (RCTs), including cluster randomized

1293. Nonopioid Pharmacologic Treatments for Chronic Pain: Appendix G (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-apg.xlsx
      January 01, 2019 - Randomized Controlled Trials Author, Year (Full Citations Appear in Appendix C.

1294. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/wireless-motility-capsule_research-protocol.pdf
      March 14, 2012 - • We will include all types of studies (e.g., randomized controlled trials, cohort studies, case …  We will include all types of studies (e.g., randomized controlled trials, cohort studies, case series

1295. Disposition of Comments_Comparative Effectiveness Review No. 256: Effectiveness of Telehealth for Women's Preventive Services (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-256-telehealth-women-disposition-comments.pdf
      June 16, 2022 - Efficacy of a web based safety decision aid for women experiencing intimate partner violence: randomized … controlled trial. … for intervention group in one trial. … helpful safety behaviors for the intervention group in one trial. … performance of interventions in real world conditions (effectiveness) rather than under ideal and controlled

1296. Cancer-Pancreas Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-pancreas_research-protocol.pdf
      August 09, 2013 - We will search the following databases using controlled vocabulary and text words: EMBASE®, MEDLINE® … Thus, if the studies had controlled for the confounders, the effect would have been even larger. … A cohort study of summary reports of controlled trials. JAMA. 1990 Mar 9;263(10):1401-5. … Direction and impact of language bias in meta-analyses of controlled trials: empirical study. … For non-randomized trials, did the study employ any other methods to enhance group comparability?

1297. serious-mental-illness-outcomes-140303 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-outcomes_research-protocol.pdf
      March 03, 2014 - outpatient, primary care or mental health (specialty) care § None Study design § Systematic reviews § Randomized … controlled trials § Nonrandomized controlled trials § Prospective and retrospective cohort studies

1298. PULMONARY with "Discussions" in Exec Summary (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/13_pulmonary_potential_high_impact_2012-12-11.pdf
      January 01, 2012 - in patients with CF who have two copies of the CFTR-F508del mutation, according to recent phase II trial … In a randomized, double-blind, placebo-controlled, phase III clinical trial, cosponsored by the Cystic … patients with CF who have two copies of the CFTR-F508del mutation, according to recent, phase II trial … Based on positive clinical-trial results, ivacaftor appears to have a sound theory underlying its mechanism

1299. Dental Care for People With Hemophilia: A Rapid Response Literature Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/hemophilia-dental-rapid-response.pdf
      July 01, 2024 - research librarian developed a comprehensive search strategy to search PubMed® and Embase® for SRs, randomized … controlled trials (RCTs), controlled observational studies, and clinical practice guidelines. … Disease Control and Prevention, National Institutes of Health, World Health Organization); clinical trial … controlled trials and practice guidelines. … controlled trial SME Subject matter expert SR Systematic Review UKHCDO United Kingdom Haemophilia

1300. #06 Developmental Delays ADHD, and Autism (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1306.pdf
      June 01, 2013 - A randomized controlled trial of oxytocin nasal spray to treat youth diagnosed with autism spectrum