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Total Results: 1,519 records

Showing results for "randomized controlled trial".

1241. Cover Page (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/it-architecture-for-post-marketing-surveillance-arizona-cert.pdf
      September 01, 2007 - heart attacks and strokes on prolonged use was not detected by the MedWatch system but rather through controlled … For example, a paper describing randomized control trials conducted to evaluate the effectiveness of … Brewer N, Lykens M, Harris LE, Newell JA, Collins J, Tierney WM (2002) "Issues in conducting randomized … controlled trials of health services research interventions in nonacademic practice settings: the

1242. Noninvasive Testing for Coronary Artery Disease (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-disease-testing_research-protocol.pdf
      January 15, 2015 - ; PET = positron emission tomography; PTCA = percutaneous transluminal coronary angioplasty; RCT = randomized … controlled trial; SPECT = single photon emission computed tomography; STEMI = ST-segment elevation … Randomized controlled trials (RCTs) as well as observational studies will be considered and those included … guidance from the AHRQ Methods Guide for Effectiveness and Comparative Effectiveness Reviews. 15 Randomized … of diagnostic testing and statistical methods of assessing this may be misleading.18, 21 Clinical trial

1243. Depression-Postpartum-Screening Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_executive.pdf
      May 01, 2013 - These included searches of trial registry and conference abstract databases for relevant articles from … controlled trial [RCT] vs. observational). … One fair-quality RCT found improvement in EPDS scores at 6 months in women randomized to screening … found low rates of appropriate followup in the majority of studies, with a notable exception in a trial … data could, in turn, be used to estimate the size, costs, and value of information of a comparative trial

1244. Treatments for Fecal Incontinence: Current State of the Evidence (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_clinician.pdf
      July 01, 2016 - events sometimes occur after surgery for fecal incontinence, and these events were underidentified in randomized … controlled trials (RCTs) alone. �� Addressing the variability in definitions for fecal incontience

1245. Prostate-Cancer-Risk-Assessment-Genes Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_executive.pdf
      July 01, 2012 - suggested a wide range of other risk factors for prostate cancer, but these have not been confirmed in controlled … the disease in symptomatic men (but not for screening asymptomatic men).14 A meta- analysis of seven randomized … controlled trials of screening using PSA testing alone, or in combination with digital rectal examination … Screening for prostate cancer: Systematic review and meta-analysis of randomised controlled trials. … in the prostate component of the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial

1246. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/telehealth_disposition-comments.pdf
      June 30, 2016 - [Cluster- Randomized Trial of a Mobile Phone Personalized Behavioral Intervention for Blood Glucose … [WellDoc™ Mobile Diabetes Management Randomized Controlled Trial: Change in Clinical and Behavioral … Implant-based multiparameter telemonitoring of patients with heart failure (IN-TIME): a randomised controlled … Trial. … trial.

1247. Dental Care for People With Sickle Cell Disease: A Rapid Response Literature Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/sickle-cell-dental-rapid-response.pdf
      July 01, 2024 - controlled trials, controlled observational studies, and clinical practice guidelines. … Disease Control and Prevention, National Institutes of Health, World Health Organization); clinical trial … controlled trials and practice guidelines. … A double-blind randomized trial of low-dose oral urea to prevent sickle cell crises J Chronic Dis, 35 … controlled trial SCD Sickle Cell Disease SME Subject Matter Expert SR Systematic review UK United

1248. Version 2_Risk of Reinfection From SARS-CoV-2 -- An Update of an Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity: A Living Rapid Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-2-risk-of-reinfection-from-SARSCoV2_0.pdf
      December 31, 2022 - Planned Updates For this update, we modified our search strategies to focus on identifying longitudinal controlled … Comparative Trial Netherlands Patients with PCR confirmed COVID- 19 disease, age >18 years. … interventional trial France Group 1: SARS-CoV-2 naive participants (participants without antecedent … interventional trial Mali Group 1: Hospitalized patients in one of the four centers in Bamako … A general parametric approach to the meta‐analysis of randomized clinical trials.

1249. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/vaccine-safety_research-protocol.pdf
      September 18, 2012 - rule out overt toxicity and identify potential toxic effects that might occur during the clinical trial … Investigational New Drug application must be submitted so that the FDA can monitor the safety of clinical trial

1250. Gestational-Diabetes-Screening-Diagnosis Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/gestational-diabetes-screening-diagnosis_executive.pdf
      October 01, 2012 - ), ClinicalTrials.gov, and Current Controlled Trials. … We included published randomized controlled trials (RCTs), nonrandomized controlled trials (NRCTs), … BMI = body mass index; RCT = randomized controlled trial studies may not have had the power to detect … Gestational diabetes mellitus screening and diagnosis: a prospective randomised controlled trial comparing … A multicenter, randomized trial of treatment for mild gestational diabetes.

1251. MEDICAL MANAGEMENT OF CONGESTIVE HEART FAILURE AND THE EFFECTIVENESS OF ISOSORBIDE DINITRATE AND HYDRALAZINE (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/congestive-heart-failure-medicines_research.pdf
      March 01, 2010 - Health Care Research Report Number 19 1 Introduction In 1986, the Vasodilator in Heart Failure Trial … combination of hydralazine and isosorbide dinitrate (H-ISDN) compared to placebo.1 The V-HeFT-II trial … the superiority of an angiotensin converting enzyme inhibitor (ACEI) over H-ISDN,2 and subsequent randomized … Results of the survival and ventricular enlargement trial. The SAVE Investigators. … A clinical trial of the angiotensin- converting-enzyme inhibitor trandolapril in patients with left

1252. Research White Paper - Assessing the Predictive Validity of Strength of Evidence Grades: A Meta-Epidemiological Study (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/grades-predictive-values_white-paper.pdf
      September 01, 2015 - Library from 2010 onward to find Cochrane reports that: (1) include an outcome with more than eight randomized … controlled trials (RCTs) on therapeutic interventions that had been graded as high SOE; (2) present

1253. An Evidence Review of Active Surveillance in Men with Localized Prostate Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-surveillance_disposition-comments.pdf
      December 01, 2011 - Randomized controlled studies (RCT’s) are the method of choice to determine the appropriate care for … Peer Reviewer 5 Results p.100 line 26: PIVOT trial. … We have provided additional information on harms from randomized trials. … controlled trials ("RCTs") comparing conventional radiation to proton therapy. … If a trial to compare AS vs.

1254. Guidance for the Conduct and Reporting of Modeling and Simulation Studies in the Context of Health Technology Assessment (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/decision-models-guidance_methods.pdf
      October 01, 2016 - Clinical trial simulation in drug development. Therapie. 2004 May;59(3):287-304. … Clinical trial simulation in drug development. Pharm Res. 2000;17(3):252- 56. … controlled trials. … controlled trials. … The use of propensity scores and observational data to estimate randomized controlled trial generalizability

1255. Breast-Biopsy-Update Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
      September 01, 2014 - positive or negative predictive value; (4) were prospective or retrospective cohort studies (including randomized … controlled trials); and (5) enrolled 10 or more patients and followed at least 50 percent of them … tool,17 and the checklist proposed by Drummond et al.,18 to assess nonrandomized cohort studies, randomized … controlled trials, and studies of resource utilization and costs, respectively. 5 Data Synthesis … We believe that a randomized comparison of alternative biopsy methods would not be fruitful because

1256. Diabetes Mellitus (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_june_2012.pdf
      January 01, 2012 - A phase III trial comparing use of Oral-lyn as a prandial insulin to injected human insulin was expected … o Extended-release exenatide is a controlled-release, once-weekly formulation delivered by subcutaneous … In September 2011, the company announced plans for its phase III trial after releasing final 48-week … results from its phase II trial. … Another research expert noted that another clinical trial compared this intervention to behavioral

1257. Disposition of Comments for Interventions for the Prevention of Posttraumatic Stress Disorder (PTSD) in Adults After Exposure to Psychological Trauma (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_disposition-comments.pdf
      April 02, 2013 - As PTSD only became an official diagnosis in 1986, it is not surprising that large well-controlled prevention … inpatient psychotherapeutic treatment versus continued outpatient psychotherapy on psychosocial outcome: a randomized … controlled trial in trauma patients. … harmful, one would at least expect to see an increase in scores, although this may reflect that some trial … Again reference to single CISD finding seems inconsistent with the review conventions: “The single trial

1258. genetic-testing-developmental-disabilities-protocol-140930 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/genetic-testing-developmental-disabilities_research-protocol.pdf
      September 30, 2014 - The ideal type of evidence for establishing the clinical utility is from high quality randomized controlled … search other grey literature sources, such as government and specialty society Web sites, clinical trial … For clinical utility studies, randomized controlled For clinical trials, non- utility studies, … health randomized clinical trials, outcomes, observational impact on clinical or family studies … maternal:ti) 24 Limit by publication and study type #23 AND ('clinical article'/de OR 'clinical trial

1259. Executive Summary_Comparative Effectiveness Review No. 261_Postpartum Care up to 1 Year After Pregnancy: A Systematic Review and Meta-Analysis (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-261-postpartum-care-executive-summary.pdf
      June 01, 2023 - • Healthcare Delivery Strategies – Where Care Is Provided o For general postpartum care (5 randomized … controlled trials [RCTs] and 1 nonrandomized comparative study [NRCS]), whether the visit is conducted

1260. Disposition of Comments_Comparative Effectiveness Review No. 265_Radiation Therapy for Metastatic Bone Disease: Effectiveness and Harms (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-disposition-comments.pdf
      August 29, 2023 - Again, removing this trial would not change the conclusions. … Did trial inclusion criteria or baseline characteristics parse out the timing of interventions like