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Total Results: 1,523 records

Showing results for "randomized controlled trial".

1241. Disposition of Comments for Diagnostic Accuracy of Screening and Treatment of Post-Acute Coronary Syndrome Depression (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-200-comments-post-acs.pdf
      November 14, 2017 - I think it should first be shown in randomized trials that screening plus treatment has indeed a benefit … ; Jolly's BRUM Trial; Kim K-DEPACS, O'Neil MoodCare; Hunger's KORINNA Trial, Jorstad's RESPONSE Trial … ; and Roncella's STEP-IN-AMI Trial, among others). … is not the Cochrane Database of systematic reviews that was searched, but the Cochrane database of randomized … For the CODIACS trial, effects on total costs are reported.

1242. Dispostion of Comments Report for Screening for Hepatitis C Virus Infection in Adults (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_disposition-comments.pdf
      November 27, 2012 - Finally, we stand by the insufficient grade for KQ 6c, as there are two conflicting randomized trials … controlled trials or observational studies, the types of studies that are considered valid in the systematic … Moreover, your analysis only considered randomized clinical trials. … It is not correct that the review only included randomized trials. … Data from large, randomized controlled trials with clinical endpoints would be an ideal tool to make

1243. Executive Summary_Comparative Effectiveness Review No. 253: Maternal and Child Outcomes Associated With the Special Supplemental Nutritional Program for Women, Infants, and Children (WIC) (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-253-maternal-child-outcomes-wic-executive-summary.pdf
      April 01, 2022 - searched PubMed®, Embase®, CINAHL®, ERIC, SCOPUS, PsycINFO®, and the Cochrane Central Register of Controlled … None of the evidence came from randomized trials, and this led to no findings of high SOE.

1244. Depression-Postpartum-Screening Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_executive.pdf
      May 01, 2013 - These included searches of trial registry and conference abstract databases for relevant articles from … controlled trial [RCT] vs. observational). … One fair-quality RCT found improvement in EPDS scores at 6 months in women randomized to screening … found low rates of appropriate followup in the majority of studies, with a notable exception in a trial … data could, in turn, be used to estimate the size, costs, and value of information of a comparative trial

1245. Disposition of Comments for CER 183 Tonsillectomy for OSDB (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy-disposition-170415.pdf
      January 17, 2017 - In the first trial discussed above (ref 11), 2,043 children were screened to identify 187 eligible … In the second trial it was 2174 screened, 373 eligible, and 328 randomized (ref 9). … Given the extreme difficulties in conducting and funding large scale randomized trials of tonsillectomy … In a parallel trial in which children were assigned nonrandomly, ie according to parental preference … , results were similar to results in the randomized trial (ref 11).

1246. An Evidence Review of Active Surveillance in Men with Localized Prostate Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-surveillance_disposition-comments.pdf
      December 01, 2011 - Randomized controlled studies (RCT’s) are the method of choice to determine the appropriate care for … Peer Reviewer 5 Results p.100 line 26: PIVOT trial. … We have provided additional information on harms from randomized trials. … controlled trials ("RCTs") comparing conventional radiation to proton therapy. … If a trial to compare AS vs.

1247. Noninvasive Testing for Coronary Artery Disease (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-disease-testing_research-protocol.pdf
      January 15, 2015 - ; PET = positron emission tomography; PTCA = percutaneous transluminal coronary angioplasty; RCT = randomized … controlled trial; SPECT = single photon emission computed tomography; STEMI = ST-segment elevation … Randomized controlled trials (RCTs) as well as observational studies will be considered and those included … guidance from the AHRQ Methods Guide for Effectiveness and Comparative Effectiveness Reviews. 15 Randomized … of diagnostic testing and statistical methods of assessing this may be misleading.18, 21 Clinical trial

1248. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/telehealth_disposition-comments.pdf
      June 30, 2016 - [Cluster- Randomized Trial of a Mobile Phone Personalized Behavioral Intervention for Blood Glucose … [WellDoc™ Mobile Diabetes Management Randomized Controlled Trial: Change in Clinical and Behavioral … Implant-based multiparameter telemonitoring of patients with heart failure (IN-TIME): a randomised controlled … Trial. … trial.

1249. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1312.pdf
      December 01, 2013 - Initial clinical trial results suggest that insulin may improve certain cognitive measures in patients … nasal spray bottles.5,7,11 In 2013, the Alzheimer’s Disease Cooperative Study registered the largest randomized … , controlled trial to date (n=240) for this intervention for treating AD and amnestic MCI.10 Various … Experts stated that the available clinical trial data are not yet robust enough to assume efficacy … Further, only one of two insulin doses used in the trial appeared to be effective, one expert with

1250. Cover Page (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/medicine-safety-call-center_research.pdf
      September 01, 2007 - heart attacks and strokes on prolonged use was not detected by the MedWatch system but rather through controlled … For example, a paper describing randomized control trials conducted to evaluate the effectiveness of … Brewer N, Lykens M, Harris LE, Newell JA, Collins J, Tierney WM (2002) "Issues in conducting randomized … controlled trials of health services research interventions in nonacademic practice settings: the

1251. Cover Page (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/it-architecture-for-post-marketing-surveillance-arizona-cert.pdf
      September 01, 2007 - heart attacks and strokes on prolonged use was not detected by the MedWatch system but rather through controlled … For example, a paper describing randomized control trials conducted to evaluate the effectiveness of … Brewer N, Lykens M, Harris LE, Newell JA, Collins J, Tierney WM (2002) "Issues in conducting randomized … controlled trials of health services research interventions in nonacademic practice settings: the

1252. Prostate-Cancer-Risk-Assessment-Genes Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_executive.pdf
      July 01, 2012 - suggested a wide range of other risk factors for prostate cancer, but these have not been confirmed in controlled … the disease in symptomatic men (but not for screening asymptomatic men).14 A meta- analysis of seven randomized … controlled trials of screening using PSA testing alone, or in combination with digital rectal examination … Screening for prostate cancer: Systematic review and meta-analysis of randomised controlled trials. … in the prostate component of the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial

1253. Making Healthcare Safer IV Rapid Response_Active Surveillance Culturing of Clostridioides difficile and Multidrug-Resistant Organisms: Methicillin-Resistant Staphylococcus aureus, Carbapenem-Resistant Enterobacterales, and Candida auris (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-active-infection-rapid-response.pdf
      May 01, 2024 - facilities Ambulatory, community, or other outpatient settings Type of studies Original studies (Randomized … controlled trials or observational studies with a comparison group, including pre-post studies), systematic … Our searches identified no eligible systematic reviews or randomized controlled trials. … ti] OR comments[ti] OR editorial[ti] OR letter[ti] OR news[ti] OR ((protocol[ti] AND (study[ti] OR trial … Risk of bias assessment for non-randomized studies Author, Year Confounding Patient Selection

1254. Treatments for Fecal Incontinence: Current State of the Evidence (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_clinician.pdf
      July 01, 2016 - events sometimes occur after surgery for fecal incontinence, and these events were underidentified in randomized … controlled trials (RCTs) alone. �� Addressing the variability in definitions for fecal incontience

1255. MEDICAL MANAGEMENT OF CONGESTIVE HEART FAILURE AND THE EFFECTIVENESS OF ISOSORBIDE DINITRATE AND HYDRALAZINE (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/congestive-heart-failure-medicines_research.pdf
      March 01, 2010 - Health Care Research Report Number 19 1 Introduction In 1986, the Vasodilator in Heart Failure Trial … combination of hydralazine and isosorbide dinitrate (H-ISDN) compared to placebo.1 The V-HeFT-II trial … the superiority of an angiotensin converting enzyme inhibitor (ACEI) over H-ISDN,2 and subsequent randomized … Results of the survival and ventricular enlargement trial. The SAVE Investigators. … A clinical trial of the angiotensin- converting-enzyme inhibitor trandolapril in patients with left

1256. PULMONARY with "Discussions" in Exec Summary (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/13_pulmonary_potential_high_impact_june_2012.pdf
      January 01, 2012 - Another drug, roflumilast, failed to meet its primary endpoints in a just-completed phase III trial … In a randomized, double-blind, placebo-controlled, phase III, clinical trial, cosponsored by the Cystic … patients with CF who have two copies of the CFTR-F508del mutation, according to recent, phase II trial … and is simpler to administer than the injected drug. 28 Oral treprostinil was investigated in a randomized … phase III clinical trial.

1257. Guidance for the Conduct and Reporting of Modeling and Simulation Studies in the Context of Health Technology Assessment (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/decision-models-guidance_methods.pdf
      October 01, 2016 - Clinical trial simulation in drug development. Therapie. 2004 May;59(3):287-304. … Clinical trial simulation in drug development. Pharm Res. 2000;17(3):252- 56. … controlled trials. … controlled trials. … The use of propensity scores and observational data to estimate randomized controlled trial generalizability

1258. Gestational-Diabetes-Screening-Diagnosis Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/gestational-diabetes-screening-diagnosis_executive.pdf
      October 01, 2012 - ), ClinicalTrials.gov, and Current Controlled Trials. … We included published randomized controlled trials (RCTs), nonrandomized controlled trials (NRCTs), … BMI = body mass index; RCT = randomized controlled trial studies may not have had the power to detect … Gestational diabetes mellitus screening and diagnosis: a prospective randomised controlled trial comparing … A multicenter, randomized trial of treatment for mild gestational diabetes.

1259. Disposition of Comments for Interventions for the Prevention of Posttraumatic Stress Disorder (PTSD) in Adults After Exposure to Psychological Trauma (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_disposition-comments.pdf
      April 02, 2013 - As PTSD only became an official diagnosis in 1986, it is not surprising that large well-controlled prevention … inpatient psychotherapeutic treatment versus continued outpatient psychotherapy on psychosocial outcome: a randomized … controlled trial in trauma patients. … harmful, one would at least expect to see an increase in scores, although this may reflect that some trial … Again reference to single CISD finding seems inconsistent with the review conventions: “The single trial

1260. Breast-Biopsy-Update Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
      September 01, 2014 - positive or negative predictive value; (4) were prospective or retrospective cohort studies (including randomized … controlled trials); and (5) enrolled 10 or more patients and followed at least 50 percent of them … tool,17 and the checklist proposed by Drummond et al.,18 to assess nonrandomized cohort studies, randomized … controlled trials, and studies of resource utilization and costs, respectively. 5 Data Synthesis … We believe that a randomized comparison of alternative biopsy methods would not be fruitful because