-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ear-infection_research-protocol.pdf
August 07, 2012 - antihistamines and decongestants for the treatment of OME has been extensively studied
in primary randomized … controlled trials (RCTs) and summarized in recent systematic reviews19, 20 and
clinical practice guidelines … Category Criteria for Inclusion
Study design Meta-analyses, systematic reviews, RCTs, and nonrandomized controlled … with persistent bilateral otitis media with effusion in primary care: double blind
randomised placebo controlled … trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_disposition-comments.pdf
April 22, 2013 - Controlled
Clin Trials 1990;11:339, Verhagen AP et al. … I think you put too much emphasis on a
poor trial (Hoffman). … In addition, you have a fair trial on metformin that
provides more reliable results. … We reviewed our quality rating for this study and
confirmed it meets criteria for a “good” trial. … management of antipsychotic-induced weight gain:
systematic review and meta-analysis of randomised
controlled
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/child-growth-development-outcomes-draft-report-rob.xlsx
January 01, 2017 - RCT
RefID Author, year
(Trial/Study Name if applicable) Is randomization adequate? … Yes Yes Low Yes- (KQ4) RCT to evaluate the developmental outcomes of children at 6 y.o in the IFOS trial … Quality Rating Non-randomized
Cohort
RefID Author, year
(Trial/study name if applicable) Did the … Quality Rating Non-randomized
-
effectivehealthcare.ahrq.gov/sites/default/files/suppl-1-user-guide-to-ocer_130129.pdf
January 01, 2011 - However, the classic
discussions of these concepts mainly focus on the
extent to which estimates from randomized … Likewise, randomized trial designs
have limited ability to identify average treatment
effects for those … patients not studied (i.e., patients
not meeting trial inclusion criteria or refusing to
participate … whether
surgery rates from AMI patients should increase
(objective 4) in comparison to existing randomized … controlled trial (RCT) evidence.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd_research-protocol.pdf
August 10, 2010 - Strategies will use
combinations of controlled vocabulary (medical subject headings, keywords) and text … Data Synthesis
Qualitative synthesis
For each trial, information on population characteristics (including … Additionally, if there are sufficient studies we
will explore trial specific factors such as 1) duration
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pqmp-protocol.pdf
April 01, 2014 - Published Literature Search
We will search PubMed, Embase, CINAHL, Cochrane Central Register of Controlled … When assessing randomized controlled trials (RCTs), we will use
6
6
the seven items in the … performance bias, detection bias, attrition bias, reporting bias, and other bias.18 When assessing
non-randomized
-
effectivehealthcare.ahrq.gov/sites/default/files/cardiovascular-horizon-scan-high-impact-1412.pdf
December 01, 2014 - PMA
trial). … However,
several experts commented about the lack of randomized controlled trial data. … trial. … PREVAIL study: prospective randomized
evaluation of the Watchman LAA closure device
in patients with … controlled trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-nerve-blocks-disposition-comments.pdf
August 15, 2025 - We cannot
say with certainty what the relative distribution of poorly
controlled pain, new persistent … To better understand that we extracted any information
offered by the trial authors regarding geographical … We did not require certain diagnosis criteria to be included in
the randomized controlled trials (RCTs … is collected as per the
protocol of the individual RCT, and we extracted demographic
data from the trial
-
effectivehealthcare.ahrq.gov/sites/default/files/interventions-horizon-scan-high-impact-1306.pdf
June 01, 2013 - , controlled trial evaluating
the effect of pharmacist-led motivational interviewing-based behavioral … trial. … controlled
effectiveness trial [abstract]. … of
patients discharged from the hospital on drug
related problems and compliance: design of a
randomized … controlled trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/predictors-trauma-care_research-protocol.pdf
May 31, 2017 - The studies maybe randomized trials or prospective or retrospective
observational studies. … key
organizations such as the American College of Surgeons, and searches of the
ClinicalTrials.gov trial … Abstracted information relevant for
assessing applicability will include the number of patients randomized … of Individual Studies
Predefined criteria will be used to assess the risk of bias for individual controlled … 5 and 13
15 limit 14 to humans
Database: EBM Reviews - Cochrane Central Register of Controlled
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
April 01, 2015 - Literature Search Strategy
We used bibliographic databases to identify publications
on randomized controlled … Relevant bibliographic databases for this
topic include MEDLINE®, the Cochrane Central Register
of Controlled … Survival in MS: a
randomized cohort study 21 years after the start of the pivotal IFN-
1b trial. … Informed shared decision
making about immunotherapy for patients with multiple sclerosis
(ISDIMS): a randomized … controlled trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_executive.pdf
May 01, 2010 - The FDA drug approval process
mandates randomized clinical trials that demonstrate
efficacy and safety … components, we made
use of different categories of studies classified by study
design and quality:
• Randomized … controlled trials (RCTs) on the five
selected indications of intracranial hemorrhage,
massive bleeding … ff
ic
ie
nt
f
or
c
om
pa
ri
ng
h
ar
m
s
an
d
be
ne
fi
ts
.
15
KQ=Key Question; RCT=randomized … controlled trial; OBS=comparative observational study; TE=thromboembolic; RBC=red blood cell;
NA=not
-
effectivehealthcare.ahrq.gov/sites/default/files/osteoarthritis-knee-update-disposition.pdf
May 04, 2017 - The
review of the literature appears to be
very comprehensive and appears to
have captured all randomized … controlled
clinical trials in to 2016. … TEP Reviewer
#4
Discussion
/Conclusio
n
Page 67 line 35-27: It appears that trial
sample size … nerve
stimulation on pain, pain sensitivity, and
function in people with knee
osteoarthritis: a randomized … controlled
trial."
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-knee-update-disposition-archived.pdf
May 04, 2017 - The
review of the literature appears to be
very comprehensive and appears to
have captured all randomized … controlled
clinical trials in to 2016. … TEP Reviewer
#4
Discussion
/Conclusio
n
Page 67 line 35-27: It appears that trial
sample size … nerve
stimulation on pain, pain sensitivity, and
function in people with knee
osteoarthritis: a randomized … controlled
trial."
-
effectivehealthcare.ahrq.gov/products/treatment-effects-bias/research
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_research-protocol.pdf
June 11, 2014 - After PPH has been
controlled, followup management varies and may include laboratory testing (e.g., … not having value for PPH management
Abbreviations: KQ=key question; ICU=Intensive Care Unit; RCT=randomized … controlled trial
Source: www.effectivehealthcare.ahrq.gov
Published online: June 11, 2014 … We will use the Cochrane Risk of
Bias tool50 for randomized controlled trials and the Newcastle-Ottawa … trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/health-careassociated-infections_disposition-comments.pdf
November 30, 2012 - the other more useful.
16 Peer Reviewer
#2
General
Comments
I find the discussion of cluster randomized … compliance with key
components of the intervention if this is found to be
unsatisfactory during the trial … The cluster randomized trials included in this report
did use run in periods and could be considered … it is
not clear why this method was singled out in the summation (as
opposed to adaptive cluster randomized … “A Randomized Double-Blind
Controlled Trial of Taurolidine-Citrate Catheter Locks for the
Prevention
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer-update_executive.pdf
December 01, 2014 - controlled trials (RCTs) and
nonrandomized comparative studies (observational, case-
control, and cohort … We searched
the following databases:
• MEDLINE®
• EMBASE®
• Cochrane Controlled Trials Register … After a MEDLINE
search of the NCT (National Clinical Trial) number(s) and
title(s), we did not find … controlled trial. … trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/sickle-cell-dental-rapid-response.pdf
July 01, 2024 - controlled trials, controlled observational studies, and clinical practice
guidelines. … Disease Control and Prevention, National Institutes of Health, World Health Organization); clinical trial … controlled trials and practice guidelines. … A double-blind randomized trial of low-dose oral urea to
prevent sickle cell crises J Chronic Dis, 35 … controlled trial
SCD Sickle Cell Disease
SME Subject Matter Expert
SR Systematic review
UK United
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/improving-utility-evidence-synthesis-white-paper.pdf
April 01, 2021 - Controlled Trial Data”8 and “Treatment for Acute Pain: An Evidence Map”9 both included
clinical practice … In anticipation of
sufficient evidence, reviewers may decide to restrict to randomized controlled trials … Controlled Trial Data. … Trial
Data17
2019
National
Center for
Posttraumati
c Stress
Disorder
Yes Yes No No No No … Controlled Trial Data.