Results

Total Results: 1,524 records

Showing results for "randomized controlled trial".

1221. Disposition of Comments for Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic Treatment for Hospital-Acquired Pneumonia (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
      November 24, 2014 - pharmacodynamically optimized dosing schemes evaluated in “PK/PD” focused clinical trials, both randomized … For example, patients randomized to PK/PD antibiotic therapy vs a control group, could assess results … comorbidities), even if the PK/PD approaches are beneficial, this may be difficult to prove without a trial … Nseir S, Antimicrobial treatment for ventilator- associated tracheobronchitis: a randomized, controlled … The review should point out that there is still equipoise to do randomized trials evaluating PD relationships

1222. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/vaccine-safety_research-protocol.pdf
      September 18, 2012 - rule out overt toxicity and identify potential toxic effects that might occur during the clinical trial … Investigational New Drug application must be submitted so that the FDA can monitor the safety of clinical trial

1223. Making Healthcare Safer IV Rapid Response_Active Surveillance Culturing of Clostridioides difficile and Multidrug-Resistant Organisms: Methicillin-Resistant Staphylococcus aureus, Carbapenem-Resistant Enterobacterales, and Candida auris (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-active-infection-rapid-response.pdf
      May 01, 2024 - facilities Ambulatory, community, or other outpatient settings Type of studies Original studies (Randomized … controlled trials or observational studies with a comparison group, including pre-post studies), systematic … Our searches identified no eligible systematic reviews or randomized controlled trials. … ti] OR comments[ti] OR editorial[ti] OR letter[ti] OR news[ti] OR ((protocol[ti] AND (study[ti] OR trial … Risk of bias assessment for non-randomized studies Author, Year Confounding Patient Selection

1224. Amended Protocol: Improving Rural Health Through Telehealth-Guided Provider-to-Provider Communication (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/rural-telehealth-amended-protocol.pdf
      February 25, 2021 - countries) 7 Include Exclude Study types and designs KQ1: Comparative studies including trial … Information relevant for assessing applicability will include the number of patients randomized/eligible … Controlled trials and observational studies will be assessed using a priori established criteria consistent … If meta- analysis is performed, randomized controlled trials will be analyzed separately from observational … currently states: Information relevant for assessing applicability will include the number of patients randomized

1225. CARDIOVASCULAR (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/cardiovascular-horizon-scan-high-impact-1412.pdf
      December 01, 2014 - PMA trial). … However, several experts commented about the lack of randomized controlled trial data. … trial. … PREVAIL study: prospective randomized evaluation of the Watchman LAA closure device in patients with … controlled trial.

1226. Ch 1-User-Guide-To-Ocer 130129 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/ch_1-user-guide-to-ocer_130129.pdf
      August 13, 2012 - this disagreement occurs when different stakeholders debate whether evidence is needed from a new randomized … controlled trial or whether evidence can be obtained from an analysis of an existing database.

1227. Disposition of Comments_Comparative Effectiveness Review No. 246: Management of High-Need, High-Cost Patients: A "Best Fit" Framework Synthesis, Realist Review, and Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/hnhc-disposition-comments.pdf
      October 29, 2021 - One, the CareMore randomized controlled trial, was included in the update.

1228. Urinary-Incontinence-Treatment Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_executive.pdf
      April 01, 2012 - For Key Questions 2 and 3, we included randomized controlled trials (RCTs) that combined men and women … loss to followup and dropout patterns, and forced intention-to-treat analyses using the number of randomized … Quality CI Confidence interval NNT Number needed to treat PFMT Pelvic floor muscle training RCT Randomized … controlled trial RR Relative risk UI Urinary incontinence References 1. … Systematic review: randomized, controlled trials of nonsurgical treatments for urinary incontinence

1229. Nephropathy-Contrast-Induced Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive.pdf
      October 01, 2015 - We included randomized controlled trials (RCTs) of any intervention to prevent CIN (including administration … independently assessed each study’s risk of bias using five items from the Cochrane Risk of Bias tool for randomized

1230. Interventions-Horizon-Scan-High-Impact-1306 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/interventions-horizon-scan-high-impact-1306.pdf
      June 01, 2013 - , controlled trial evaluating the effect of pharmacist-led motivational interviewing-based behavioral … trial. … controlled effectiveness trial [abstract]. … of patients discharged from the hospital on drug related problems and compliance: design of a randomized … controlled trial.

1231. Pediatric Quality Measures Program 3.0: An Evidence Map of Measures for Vision, Hearing, and Developmental Screening and Followup (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/pqmp-protocol.pdf
      April 01, 2014 - Published Literature Search We will search PubMed, Embase, CINAHL, Cochrane Central Register of Controlled … When assessing randomized controlled trials (RCTs), we will use 6 6 the seven items in the … performance bias, detection bias, attrition bias, reporting bias, and other bias.18 When assessing non-randomized

1232. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-postpartum-screening_research-protocol.pdf
      May 01, 2013 - symptoms meet the diagnostic criteria for depression are given effective treatments, then a study that randomized … 17 Study Characteristic Inclusion Criteria Exclusion Criteria Study design • Original data • Randomized … controlled trials: All sample sizes • Observational studies: sample size ≥100 subjects • Editorials … controlled trial [RCT] versus observational study) that may be related to outcomes. … controlled trial RDC Research Diagnostic Criteria SADS Schedule for Affective Disorders and Schizophrenia

1233. Multiple-Sclerosis Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
      April 01, 2015 - Literature Search Strategy We used bibliographic databases to identify publications on randomized controlled … Relevant bibliographic databases for this topic include MEDLINE®, the Cochrane Central Register of Controlled … Survival in MS: a randomized cohort study 21 years after the start of the pivotal IFN- 1b trial. … Informed shared decision making about immunotherapy for patients with multiple sclerosis (ISDIMS): a randomized … controlled trial.

1234. Nonopioid Pharmacologic Treatments for Chronic Pain: Appendix E (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-ape_0.xlsx
      August 08, 2017 - Neuropathic Pain Author, Year Country Trial Name Quality Rating Type(s) of Pain Demographics Other Population … Characteristics N Randomized N Analyzed Intervention Duration (weeks) Funding Source Arezzo, 2008 U.S … Fibromyalgia Author, Year Country Trial Name Quality Rating Type(s) of Pain Demographics Other Population … Inflammatory Arthritis Author, Year Country Trial Name Quality Rating Type(s) of Pain Demographics Other … controlled trials; RD = risk difference; RR = rate ratio; SMD: standardized mean difference; tNSAID

1235. Treatment of Osteoarthritis of the Knee: An Update Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-knee-update-disposition-archived.pdf
      May 04, 2017 - The review of the literature appears to be very comprehensive and appears to have captured all randomized … controlled clinical trials in to 2016. … TEP Reviewer #4 Discussion /Conclusio n Page 67 line 35-27: It appears that trial sample size … nerve stimulation on pain, pain sensitivity, and function in people with knee osteoarthritis: a randomized … controlled trial."

1236. Treatment of Osteoarthritis of the Knee: An Update Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/osteoarthritis-knee-update-disposition.pdf
      May 04, 2017 - The review of the literature appears to be very comprehensive and appears to have captured all randomized … controlled clinical trials in to 2016. … TEP Reviewer #4 Discussion /Conclusio n Page 67 line 35-27: It appears that trial sample size … nerve stimulation on pain, pain sensitivity, and function in people with knee osteoarthritis: a randomized … controlled trial."

1237. Executive Summary_Comparative Effectiveness Review No. 253: Maternal and Child Outcomes Associated With the Special Supplemental Nutritional Program for Women, Infants, and Children (WIC) (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-253-maternal-child-outcomes-wic-executive-summary.pdf
      April 01, 2022 - searched PubMed®, Embase®, CINAHL®, ERIC, SCOPUS, PsycINFO®, and the Cochrane Central Register of Controlled … None of the evidence came from randomized trials, and this led to no findings of high SOE.

1238. Treatments for Fecal Incontinence: Current State of the Evidence (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_clinician.pdf
      July 01, 2016 - events sometimes occur after surgery for fecal incontinence, and these events were underidentified in randomized … controlled trials (RCTs) alone. �� Addressing the variability in definitions for fecal incontience

1239. Disposition of Comments for CER 183 Tonsillectomy for OSDB (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy-disposition-170415.pdf
      January 17, 2017 - In the first trial discussed above (ref 11), 2,043 children were screened to identify 187 eligible … In the second trial it was 2174 screened, 373 eligible, and 328 randomized (ref 9). … Given the extreme difficulties in conducting and funding large scale randomized trials of tonsillectomy … In a parallel trial in which children were assigned nonrandomly, ie according to parental preference … , results were similar to results in the randomized trial (ref 11).

1240. Head-Neck-Cancer-Update Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer-update_executive.pdf
      December 01, 2014 - controlled trials (RCTs) and nonrandomized comparative studies (observational, case- control, and cohort … We searched the following databases: • MEDLINE® • EMBASE® • Cochrane Controlled Trials Register … After a MEDLINE search of the NCT (National Clinical Trial) number(s) and title(s), we did not find … controlled trial. … trial.