Results

Total Results: 1,519 records

Showing results for "randomized controlled trial".

1201. pediatric-EHR-protocol-140818 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/pediatric-ehr_research-protocol.pdf
      January 01, 2014 - Examples of sources of grey literature include government websites, clinical trial databases, trade … Designs: We will allow randomized controlled trials, cohort, and pre-post study designs because these … population Pediatric, outpatient Publication languages English only Admissible evidence Study design Randomized … controlled trials, including wait-list control, cohorts with comparison, pre-post cohort without comparison

1202. Urinary-Incontinence-Treatment Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_executive.pdf
      April 01, 2012 - For Key Questions 2 and 3, we included randomized controlled trials (RCTs) that combined men and women … loss to followup and dropout patterns, and forced intention-to-treat analyses using the number of randomized … Quality CI Confidence interval NNT Number needed to treat PFMT Pelvic floor muscle training RCT Randomized … controlled trial RR Relative risk UI Urinary incontinence References 1. … Systematic review: randomized, controlled trials of nonsurgical treatments for urinary incontinence

1203. Technical Brief Protocol: Impact of Community Health Worker Certification on Workforce and Service Delivery for Asthma and Other Selected Chronic Diseases (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/community-health-worker-protocol.pdf
      March 26, 2019 - conducted outside of the United States Study design • Studies with a comparison group, such as randomized … controlled trials, nonrandomized controlled trials, before/after studies, cross-sectional, or historical … Information Management Aided, where appropriate, by controlled vocabulary terms and text words, we will

1204. Glasgow Coma Scale for Field Triage of Trauma: A Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/field-triage-glascow_executive.pdf
      January 01, 2017 - For all Key Questions, we included cohort studies and randomized trials that directly compared the … of the mGCS versus the tGCS were published in 1998 and 2003.18,19 The Cochrane Central Register of Controlled … A number of studies on predictive utility were conducted in ED settings, which is more controlled and … Research Recommendations Head-to-head observational or randomized studies that assess one set of patients … Randomized controlled trial of a scoring aid to improve Glasgow Coma Scale scoring by emergency medical

1205. Arthritis and Nontraumatic Joint Disease (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/arthritis_hi_impact.pdf
      January 01, 2014 - concurred that there is an unmet need for treatment options for patients whose chronic gout is not well controlled … indomethacin plus rilonacept, and 2.7% with rilonacept alone).” 22 In a second double-blind, placebo-controlled … However, some of the experts stated that large, randomized, double-blind trials are needed to better … perspectives stated that PRP injections could gain larger acceptance if shown to be effective in randomized … Trial watch: BLYS-targeted antibody shows promise in Phase III SLE trial.

1206. Asthma-Immunotherapy-2011 Research (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2011_research.pdf
      January 01, 2011 - estimating nonrandomized therapeutic studies were significantly lower when compared with well designed randomized … controlled clinical trials. … Methodological index for non-randomized studies (minors): development and validation of a new instrument … Improving the completeness and transparency of reports of randomized trials in oral health: the CONSORT … with concurrent controls D Cohort (retrospective) study with concurrent controls E Case-controlled

1207. Disposition of Comments for Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic Treatment for Hospital-Acquired Pneumonia (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
      November 24, 2014 - pharmacodynamically optimized dosing schemes evaluated in “PK/PD” focused clinical trials, both randomized … For example, patients randomized to PK/PD antibiotic therapy vs a control group, could assess results … comorbidities), even if the PK/PD approaches are beneficial, this may be difficult to prove without a trial … Nseir S, Antimicrobial treatment for ventilator- associated tracheobronchitis: a randomized, controlled … The review should point out that there is still equipoise to do randomized trials evaluating PD relationships

1208. Protocol Amendment - Safety of Vaccines 030413 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccines-safety-protocol-130325.pdf
      September 18, 2012 - rule out overt toxicity and identify potential toxic effects that might occur during the clinical trial … Investigational New Drug application must be submitted so that the FDA can monitor the safety of clinical trial … retrospective observational studies that compare vaccine recipients with an unvaccinated group, self-controlled … retrospective observational studies that compare vaccine recipients with an unvaccinated group, self-controlled

1209. Dementia-Nursing-Home-Characteristics Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/dementia-nursing-home-characteristics_executive.pdf
      October 01, 2012 - We included 14 published articles: 9 randomized controlled trials (RCTs), 1 nonrandomized controlled … trial, and 4 prospective cohort studies.

1210. Nonopioid Pharmacologic Treatments for Chronic Pain: Appendix E (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-ape_0.xlsx
      August 08, 2017 - Neuropathic Pain Author, Year Country Trial Name Quality Rating Type(s) of Pain Demographics Other Population … Characteristics N Randomized N Analyzed Intervention Duration (weeks) Funding Source Arezzo, 2008 U.S … Fibromyalgia Author, Year Country Trial Name Quality Rating Type(s) of Pain Demographics Other Population … Inflammatory Arthritis Author, Year Country Trial Name Quality Rating Type(s) of Pain Demographics Other … controlled trials; RD = risk difference; RR = rate ratio; SMD: standardized mean difference; tNSAID

1211. CER 225: Evidence Summary Interventions for Substance Use Disorders in Adolescents: A Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/cer-225-substance-abuse-adolescents-evidence-summary%20225%20Substance%20Use%20Adolescents.pdf
      May 01, 2020 - Results We found 118 randomized controlled trials that evaluated treatment of adolescents or young

1212. September 2021 Surveillance Report 1: Comparative Effectiveness Review No. 250: Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-other-plant-based-treatments-surveillance-report-1-updated_0.PDF
      December 01, 2021 - Results to Date Results Overview The systematic review included evidence from 27 studies (20 randomized … controlled trials and 7 observational studies), all assessing cannabis interventions (see the full

1213. Disposition of Comments for Interventions To Improve Cardiovascular Risk Factors in People With Serious Mental Illness (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_disposition-comments.pdf
      April 22, 2013 - Controlled Clin Trials 1990;11:339, Verhagen AP et al. … I think you put too much emphasis on a poor trial (Hoffman). … In addition, you have a fair trial on metformin that provides more reliable results. … We reviewed our quality rating for this study and confirmed it meets criteria for a “good” trial. … management of antipsychotic-induced weight gain: systematic review and meta-analysis of randomised controlled

1214. Suppl-1-User-Guide-To-Ocer 130129 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/suppl-1-user-guide-to-ocer_130129.pdf
      January 01, 2011 - However, the classic discussions of these concepts mainly focus on the extent to which estimates from randomized … Likewise, randomized trial designs have limited ability to identify average treatment effects for those … patients not studied (i.e., patients not meeting trial inclusion criteria or refusing to participate … whether surgery rates from AMI patients should increase (objective 4) in comparison to existing randomized … controlled trial (RCT) evidence.

1215. Draft - Primary Hypofractionated Radiation Therapy for Localized Prostate Cancer: Appendix D2 Tables (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-draft-appendix-d2.xlsx
      January 01, 2024 - Intervention Details Author, year KQ Trial Arms, number Arm Group Total dose, Gy Total number of fractions … Dose constraints were applied to organs at risk and were amended during the trial… Androgen deprivation … Rectal balloon used for planning only No NR No NR Kishan, 2023 KQ5 IG1 IG1 40 5 8 UHF NR Patients were randomized … MRI No NR No NR Yes Full bladder, Empty rectum Kishan, 2023 KQ5 IG2 IG2 40 5 8 UHF NR Patients were randomized … (Computed tomography) No NR No NR No NR No NR No NR Wang, 2022 KQ1 IG2 IG2 78 39 2 CF NR Patients randomized

1216. Nephropathy-Contrast-Induced Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive.pdf
      October 01, 2015 - We included randomized controlled trials (RCTs) of any intervention to prevent CIN (including administration … independently assessed each study’s risk of bias using five items from the Cochrane Risk of Bias tool for randomized

1217. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-postpartum-screening_research-protocol.pdf
      May 01, 2013 - symptoms meet the diagnostic criteria for depression are given effective treatments, then a study that randomized … 17 Study Characteristic Inclusion Criteria Exclusion Criteria Study design • Original data • Randomized … controlled trials: All sample sizes • Observational studies: sample size ≥100 subjects • Editorials … controlled trial [RCT] versus observational study) that may be related to outcomes. … controlled trial RDC Research Diagnostic Criteria SADS Schedule for Affective Disorders and Schizophrenia

1218. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-screening_research-protocol.pdf
      May 18, 2011 - Study Design KQs 1–2: Systematic review, randomized or nonrandomized controlled trial, prospective … databases: MEDLINE Cochrane Database of Systematic Reviews Cochrane Central Register of Controlled … For the purposes of this review, grey literature comprises information that is not controlled by commercial … and manufacturer Web sites, and information regarding ongoing and future research via clinical trial

1219. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd_research-protocol.pdf
      August 10, 2010 - Strategies will use combinations of controlled vocabulary (medical subject headings, keywords) and text … Data Synthesis Qualitative synthesis For each trial, information on population characteristics (including … Additionally, if there are sufficient studies we will explore trial specific factors such as 1) duration

1220. Ch 1-User-Guide-To-Ocer 130129 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/ch_1-user-guide-to-ocer_130129.pdf
      August 13, 2012 - this disagreement occurs when different stakeholders debate whether evidence is needed from a new randomized … controlled trial or whether evidence can be obtained from an analysis of an existing database.