-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_surveillance.pdf
March 01, 2013 - , non-
blinded 6 month controlled trial
reported that adalimumab
combined with cyclosporine led to … , double-
blind, placebo-controlled, phase II trial. … , placebo-controlled trial. … A randomized placebo-controlled trial of
methotrexate in psoriatic arthritis. … Controlled Trial; SCEPC: Southern California Evidence-based Practice Center; TNF: Tumor Necrosis Factor
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-addendum-app.xlsx
October 08, 2025 - Evidence table for a randomized controlled trial evaluating external beam radiation therapy for the palliative … , Year KQ Addressed Comparison Country
Number of Centers and Setting Inclusion/Exclusion Criteria N Randomized … Allergy to contrast dye used in MRIs/CT scans or cannot be premedicated for the use of contract dye N randomized … metastatic spinal cord compression
NR not reported
NRS numerical rating scale
QOL quality of life
RCT randomized … controlled trial
SD standard deviation
USA United States of America
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tx-for-localized-prostate-cancer_surveillanceassesment_20120614.pdf
May 01, 2012 - Additional
randomized controlled trials
(RCTs) are needed. … , Randomized Controlled Trial, Clinical Trial, Phase I, Clinical Trial, Phase II,
Clinical Trial, Phase … , Randomized Controlled Trial, Clinical Trial, Phase I, Clinical Trial, Phase
II, Clinical Trial, Phase … Viani, 200918 -- Total patient
population =
2812; 7 studies
included
Randomized, controlled
studies … Additional randomized
controlled trials (RCTs) are needed.
-
effectivehealthcare.ahrq.gov/sites/default/files/tx-for-localized-prostate-cancer_surveillanceassesment_20120614.pdf
May 01, 2012 - Additional
randomized controlled trials
(RCTs) are needed. … , Randomized Controlled Trial, Clinical Trial, Phase I, Clinical Trial, Phase II,
Clinical Trial, Phase … , Randomized Controlled Trial, Clinical Trial, Phase I, Clinical Trial, Phase
II, Clinical Trial, Phase … Viani, 200918 -- Total patient
population =
2812; 7 studies
included
Randomized, controlled
studies … Additional randomized
controlled trials (RCTs) are needed.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/incident-user-design_research.pdf
May 01, 2012 - How well can non-randomized studies approximate
randomized controlled trials if they follow continuing … that obtain findings as credible as
those from randomized controlled trials. … controlled trial protocols.23 The extent of any difference in the
absolute risk probably depends on … controlled trial were required to undergo a three-month washout
period.26
Reduced Study Size as … Principal results from
the Women’s Health Initiative randomized
controlled trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-risk-of-bias.pdf
December 01, 2017 - Move Beyond Study Design
Label
• Do not rely solely on study design label (e.g.,
randomized controlled … controlled trial can have other features
that introduce risk of bias (e.g. substandard methods
to … controlled trial [RCT] or cohort, case-control) as a proxy for assessment of risk of bias of individual … Finally, not all randomized controlled trials are of equal internal validity, some can have other features … A target trial is a hypothetical randomized controlled trial of the intervention where feasibility or
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-decision-support-tools_research-protocol.pdf
November 12, 2013 - A community-based randomised controlled trial of three
different educational resources for men about … [pt] OR randomized controlled trial[pt] OR
random*[tw] OR (double[tw] AND blind*[tw]) OR double-blind … [pt] or controlled clinical trial[pt] or multicenter study[pt]))) OR ((multicentre[tw] or
multicenter … clinical trial[pt] or randomized controlled trial[pt])))) NOT (((("comment on" or
review[tw] or review … [pt:noexp] or randomized controlled trial[pt] or
controlled clinical trial[pt] or evaluation studies
-
effectivehealthcare.ahrq.gov/sites/default/files/study-size-planning-chapter-9.pptx
January 01, 2013 - in Randomized Controlled Trials (1 of 3)
The study planning needed to achieve various study sizes, and … Study Size and Power Calculations in Randomized Controlled Trials (3 of 3)
Scenario Effect of Interest … Study Size and Power Calculations in Randomized Controlled Trials (3 of 3)
The needed study size depends … In randomized controlled trials that have study size constraints due to budget or the pool of available … For a well-planned and conducted randomized controlled trial, the type I and type II errors rank higher
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_executive.pdf
January 27, 2012 - controlled trial. … controlled trial. … , placebo-controlled trial. … Topiramate for treating
alcohol dependence: a randomized controlled trial. … controlled trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mrsa-screening-2010_research-protocol.pdf
January 01, 2010 - controlled trial [pt] OR controlled clinical trial [pt] OR
Source: www.effectivehealthcare.ahrq.gov … controlled trial'/exp
OR 'randomised controlled trial'/exp OR 'controlled clinical trial'/exp OR ' … An intention-
to-treat analysis is done for randomized controlled trials.
O Poor. … For randomized controlled trials, intention-to-
treat analysis is lacking. … What to think if the results of the National Institutes of Health randomized trial of
methicillin-resistant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_addendum.pdf
February 01, 2010 - The final
analysis of the Arterial Revascularization
Therapies (ARTS) randomized trial. … The final 10-year
follow-up results from the BARI
randomized trial. … A
randomized controlled clinical trial of 3
therapeutic strategies for multivessel
coronary artery … Randomized, controlled trial of coronary
artery bypass surgery versus percutaneous
coronary intervention … A meta-analysis of randomized controlled
trials comparing coronary artery bypass
graft with percutaneous
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_executive.pdf
March 01, 2013 - controlled trial; RR = relative risk. … controlled trial; RR = relative risk. … AHA = acetohydroxamic acid; HCTZ = hydrochlorothiazide; RCT = randomized controlled trial
18
19. … controlled trial. … Randomized controlled trial of
a low animal protein, high fiber diet in the prevention of recurrent
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
January 28, 2019 - Study Designs
• Randomized controlled trials, case-controlled, cohort studies.
III. … controlled trial
7
a: Total adverse events as in the total number of subjects that experienced … controlled trial. … controlled trials as topic/
63. randomized controlled trial/
64. random allocation/
65. … , phase iv.pt.
72. controlled clinical trial.pt.
73. randomized controlled trial.pt.
74.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-protein-intake-protocol-amendment.pdf
November 29, 2023 - controlled trials (RCTs)
● Non-randomized controlled trials, including
quasi-experimental and controlled … controlled trial
8
B. … For non-randomized
controlled trials (including quasi-experimental and controlled before-and-after … Controlled Trial
RR Relative Risk
RoB Risk of Bias
TOO Task Order Officer
about:blank
16 … controlled trial or controlled clinical trial).pt. or randomi?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs-future_research.pdf
February 01, 2013 - (Appendix B)
For KQ 1, authors of the draft CER found that randomized controlled trial (RCT) results … Randomized Controlled Trials (RCTs) are likely the best approach to comparing interventions. … Controlled Trials as Topic/ (81538)
4 randomized controlled trial/ (331851)
5 random allocation … 11 clinical trial, phase iv.pt. (723)
12 controlled clinical trial.pt. (84651)
13 randomized … , double-blind,
placebo-controlled trial.”
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_executive.pdf
September 01, 2009 - and tibolone for the
primary prevention of breast cancer, mortality, and
fractures:
• Eight large randomized … placebo-controlled trials (four tamoxifen, two
raloxifene, and one tibolone). … . 0.74; one trial) reduced vertebral
fractures; tamoxifen (RR 0.66; 0.45, 0.98; one
trial) and tibolone … raloxifene, and tibolone when used for primary
prevention of breast cancer:
• In addition to the 8 large randomized … controlled
trials described in Key Question 1, harms data
were provided by 12 placebo-controlled trials
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-241-physical-activity-wheelchair-evidence-summary-updated.pdf
October 01, 2021 - Results
We included 168 studies in 197 publications (n=7,511), comprising of 146
randomized controlled … controlled trials). … Other subgroup analyses (3 randomized controlled trials)
did not find evidence of variation in effects … controlled trial
a Strength of evidence color shading: blue=high strength of evidence, green=moderate … The addition of larger, well-conducted randomized
controlled trials of longer duration and including
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-outcomes-chronic-kidney-rapid-research.pdf
November 01, 2024 - CRP
was reduced in both of the high-quality primary studies (1 RCT and 1 non-randomized controlled trial … One high quality non-randomized
controlled trial showed a significant reduction of IL1β.28
Table 2.2 … /randomized controlled observational trial
(0/226,28)
Observational study 0
Study countries India … ; RCT: randomized controlled trial; TNF-α: Tumor Necrosis Factor alpha; UACR: Urine albumin-
to-creatinine … Controlled Trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-protocol.pdf
September 24, 2024 - controlled trial. … ,
Phase III" [Publication Type] OR "Comparative Study"
[Publication Type] OR "Randomized Controlled … ,
Phase III" [Publication Type] OR "Comparative Study"
[Publication Type] OR "Randomized Controlled … ,
Phase III" [Publication Type] OR "Comparative Study"
[Publication Type] OR "Randomized Controlled … Type]
OR "randomized"[tiab] OR "trial"[tiab] OR randomized[tiab])
All kidney stones and
imaging
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_executive.pdf
March 01, 2012 - In evaluating all KQs, randomized controlled trials
(RCTs) of any size or controlled observational studies … Of the 177 articles included in search one,
120 articles represented 97 unique randomized controlled … a comparison of interest
(n=138)
Other than randomized controlled trial or
controlled observational … evaluate a comparison of interest
(n=27)
Other than randomized controlled trial or
controlled observational … controlled trial or one controlled observational study and a strength
of evidence of low, moderate,