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Total Results: 1,524 records

Showing results for "randomized controlled trial".

1181. Disposition of Comments for Local Nonsurgical Therapies for Stage I and Symptomatic Obstructive Non-Small-Cell Lung Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_disposition-comments.pdf
      June 12, 2013 - performed a thorough, deep search of the published literature, including NLM MEDLINE, EMBASE, Cochrane Controlled … alternatives for inoperable patients with stage 1 NSCLC the lack of comparative data between modalities in a randomized … It is not clear that there is equipoise present with such a trial. … Results of randomized studies looking at SBRT vs wedge or SBRT vs RFA are maturing and studies. … Randomized trials for PBRT vs IMRT are also not currently organized to my knowledge. 3.

1182. Computerized Definitions Showed High Positive Predictive Values for Identifying Reasons for Hospitalizations in a Medicaid Population with Rheumatoid Arthritis (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-hospitalizations_research.pdf
      October 01, 2008 - with adverse events such as serious infections and congestive heart failure.3-6 Available clinical trial … Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized, controlled … trial.

1183. Frameworks for Determining Research Gaps During Systematic Reviews (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-research-steps-framework_research.pdf
      June 01, 2011 - If no recent reviews of a specific topic were found, a search was made for randomized controlled trials … controlled trial, STI=sexually transmitted infection … controlled trial (RCT) for each topic.5 Research gaps/needs were identified as areas of insufficient … Controlled Trial RFA Request For Applications RTI Research Triangle Institute SBU The Swedish Council … controlled trial, RTI=Research Triangle Institute, TEP=technical expert panel, UNC=university of North

1184. CER 215 Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
      March 28, 2019 - Consider adding “not-placebo-controlled” in parentheses. This was added. … Thus if the majority of sample came from a low risk of bias trial, the ROB domain in the SOE rating … Consider separate sections for placebo-controlled and no treatment trials. … phases” should be “was conducted in two randomized phases” This change has been made. … Peer reviewer #6 Discussion Could make more explicit that people that tolerate treatment were randomized

1185. Patient-Monitoring-Systems-Appendix-C (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-monitoring-systems-appendix-c.xlsx
      January 01, 2024 - controlled trial RR risk ratio RRS rapid response system RRT rapid response team SD standard deviation … A controlled before and after study. … Comparison of Two Pediatric Early Warning Systems: A Randomized Trial. … controlled pilot trial. … trial, non-randomized Academic 1 Adult 2740 Surgical and Medical NR NR Miles, 2023 No NR 14 months

1186. Disposition of Comments_Systematic Review: Breastfeeding and Health Outcomes for Infants and Children (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-disposition-comments.pdf
      March 31, 2025 - of breastfeeding can be, and this was done in the PROBIT trial. … All of the observational analyses from the PROBIT trial are included in our review. … insufficient evidence to draw conclusions about the relationship with food allergies and no well-controlled … We also agree that randomized clinical trials, including cluster randomized trials, can help to understand … Given that randomized controlled trials (RCTs) are not feasible in breastfeeding research, we encourage

1187. The Empirical Evidence of Bias in Trials Measuring Treatment Differences | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/treatment-effects-bias/research

1188. Mixed MethodsReview -Integrating Palliative Care with Chronic Disease Management in Ambulatory Care (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/palliative-care-research-amended-protocol.pdf
      November 21, 2019 - controlled trials • Non-randomized studies with concurrent or historical controls • Articles … following databases for primary quantitative studies: PubMed, CINAHL, and the Cochrane Central Register of Controlled … For nonrandomized studies, we will use the Cochrane Risk of Bias Assessment Tool for Non-Randomized … Randomized controlled trials and nonrandomized studies will be analyzed separately. … dichotomous outcomes are presented, we will calculate a pooled effect estimate of relative risk between trial

1189. Vaginal Birth After Cesarean: Developing and Prioritizing a Future Research Agenda (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth-future_research.pdf
      August 09, 2012 - were identified by searching Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled … were identified by searching Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled … research, how much is already known about the topic in question, and the desired balance between a controlled … interviews of patients • Surveys of patients and providers • Development of decision aids • Randomized … Focus groups/interviews • Surveys of patients, clinicians, administrators, liability companies • Randomized

1190. Crosscutting-Horizon-Scan-High-Impact-1412 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1412.pdf
      December 01, 2014 - The system was studied in a randomized controlled trial that compared propofol-mediated sedation delivered … In this trial, Pambianco et al. reported that patients undergoing Sedasys-mediated propofol sedation … second such bolus for 90 seconds.8 Clinical trials: The Sedasys system was studied in an open-label, randomized … controlled trial conducted to support a premarket approval application to FDA.9 In this trial, 1,000 … Computer-assisted personalized sedation for upper endoscopy and colonoscopy: a comparative, multicenter randomized

1191. Asthma-Immunotherapy-2011 Research (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2011_research.pdf
      January 01, 2011 - estimating nonrandomized therapeutic studies were significantly lower when compared with well designed randomized … controlled clinical trials. … Methodological index for non-randomized studies (minors): development and validation of a new instrument … Improving the completeness and transparency of reports of randomized trials in oral health: the CONSORT … with concurrent controls D Cohort (retrospective) study with concurrent controls E Case-controlled

1192. Disposition of Comments for CER 166 Calcineurin Inhibitors (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/calcineurin-inhibitor_disposition-comments.pdf
      March 15, 2016 - In addition to RCTs, we also included non-randomized prospective and retrospective comparative trials … Introduction Page 3, Lines 23-24: the increased access to transplantation for individuals with well-controlled … Global Development Medical Affairs, Americas Results • Asserting improved patient outcomes based on randomized … controlled trials (RCTs) reporting only one or two year results and oftentimes lacking biopsy data … A comparative, randomized trial of concentration- controlled sirolimus combined with reduced-dose tacrolimus

1193. Disposition of Comments for Interventions To Improve Cardiovascular Risk Factors in People With Serious Mental Illness (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_disposition-comments.pdf
      April 22, 2013 - Controlled Clin Trials 1990;11:339, Verhagen AP et al. … I think you put too much emphasis on a poor trial (Hoffman). … In addition, you have a fair trial on metformin that provides more reliable results. … We reviewed our quality rating for this study and confirmed it meets criteria for a “good” trial. … management of antipsychotic-induced weight gain: systematic review and meta-analysis of randomised controlled

1194. Arthritis and Nontraumatic Joint Disease (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/arthritis_hi_impact.pdf
      January 01, 2014 - concurred that there is an unmet need for treatment options for patients whose chronic gout is not well controlled … indomethacin plus rilonacept, and 2.7% with rilonacept alone).” 22 In a second double-blind, placebo-controlled … However, some of the experts stated that large, randomized, double-blind trials are needed to better … perspectives stated that PRP injections could gain larger acceptance if shown to be effective in randomized … Trial watch: BLYS-targeted antibody shows promise in Phase III SLE trial.

1195. Technical Brief Protocol: Impact of Community Health Worker Certification on Workforce and Service Delivery for Asthma and Other Selected Chronic Diseases (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/community-health-worker-protocol.pdf
      March 26, 2019 - conducted outside of the United States Study design • Studies with a comparison group, such as randomized … controlled trials, nonrandomized controlled trials, before/after studies, cross-sectional, or historical … Information Management Aided, where appropriate, by controlled vocabulary terms and text words, we will

1196. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/undescended-testicle_research-protocol.pdf
      September 02, 2011 - literature related to nonhuman subjects, and publications not resulting from some form of clinical trial … For randomized controlled trials, the Cochrane Collaboration’s tool for assessing risk of bias will … country, city, state) and time period, population description, sample size, and study type (e.g., randomized … controlled trial, prospective observational study, etc.). 11 Source: www.effectivehealthcare.ahrq.gov

1197. Draft Comparative Effectiveness Review Appendicies (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_appendixes.pdf
      April 01, 2005 - Controlled Trials/ 38577 A-1 Appendix A. … controlled trial.pt. 204593 38 clinical trial.pt. 412355 39 controlled clinical trials/ 2929 40 ( … clin$ adj trial$).tw. 88180 41 ((singl$ or doubl$ or trebl$ or tripl$) adj (blind$ or mask$)).tw. 79196 … controlled trial Non-randomized comparative trial Prospective cohort (pre-post, single arm) Retrospective … • The randomized trial of surgical versus medical treatment, found that demographic factors did

1198. Disposition of Comments Report for Childhood Obesity Prevention Programs: A Comparative Effectiveness Review and Meta-Analysis (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/obesity-child_disposition-comments.pdf
      June 10, 2013 - methods described in this report guidance. 106 TEP 1 Methods Since many school-based studies are randomized … A randomized controlled trial of culturally tailored dance and reducing screen time to prevent weight … Two-year follow-up results for Hip-Hop to Health Jr.: a randomized controlled trial for overweight … Were multiple comparisons appropriately controlled for? … Obesity Prevention Effectiveness Trial: postintervention results.

1199. Disposition of Comments_Comparative Effectiveness Review No. 267: ADHD Diagnosis and Treatment in Children and Adolescents (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-267-adhd-disposition-comments.pdf
      March 25, 2024 - Double-Blind Placebo-Controlled Randomized Clinical Trial of Neurofeedback for Attention- Deficit/Hyperactivity … Neurofeedback for ADHD: 25-month follow-up of double-blind randomized controlled trial (2023). … EEG neurofeedback for ADHD: double-blind sham-controlled randomized pilot feasibility trial. … Double-blind placebo-controlled randomized clinical trial of neurofeedback for attention- deficit/hyperactivity … A randomized placebo- controlled trial of electroencephalographic (EEG) neurofeedback in children with

1200. Untitled (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/suicide-prevention_research-protocol.pdf
      December 23, 2015 - Methods for synthesizing findings on moderation effects across multiple randomized trials. … Prevention of Suicide in Primary Care Elderly: Collaborative Trial (PROSPECT) Prevention of Suicide … in Primary Care Elderly: Collaborative Trial (PROSPECT) aims to prevent suicide among older primary … [pt] 6 “Non-randomized”[tiab] 7 Nonrandomized[tiab] 8 cohort[tiab] 9 “next study”[tiab] 10 … ; Not convicted: Dismissed/Bench/Jury Trial; Prison; Probation only; Fine only; and, Suspended sentence