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Total Results: 1,523 records

Showing results for "randomized controlled trial".

1181. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/undescended-testicle_research-protocol.pdf
      September 02, 2011 - literature related to nonhuman subjects, and publications not resulting from some form of clinical trial … For randomized controlled trials, the Cochrane Collaboration’s tool for assessing risk of bias will … country, city, state) and time period, population description, sample size, and study type (e.g., randomized … controlled trial, prospective observational study, etc.). 11 Source: www.effectivehealthcare.ahrq.gov

1182. S89 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/s89.pdf
      October 01, 2007 - In addition, common adverse events have usually already been identified in preli- censure randomized … controlled trials, limiting their appropri- ateness for analysis with maxSPRT. … and induction of immunologic memory by a serogroup C meningococcal conjugate vaccine in infants: a randomized … controlled trial.

1183. Disposition of Comments for Local Nonsurgical Therapies for Stage I and Symptomatic Obstructive Non-Small-Cell Lung Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_disposition-comments.pdf
      June 12, 2013 - performed a thorough, deep search of the published literature, including NLM MEDLINE, EMBASE, Cochrane Controlled … alternatives for inoperable patients with stage 1 NSCLC the lack of comparative data between modalities in a randomized … It is not clear that there is equipoise present with such a trial. … Results of randomized studies looking at SBRT vs wedge or SBRT vs RFA are maturing and studies. … Randomized trials for PBRT vs IMRT are also not currently organized to my knowledge. 3.

1184. Effectiveness of Screening and Treatment of Subclinical Hypothyroidism or Hyperthyroidism (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypothyroidism-hyperthyroidism-screening-treatment_disposition-comments.pdf
      February 01, 2012 - It is a controlled clinical trial. … This study was described as a controlled trial not a randomized controlled trial.

1185. CER 215 Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
      March 28, 2019 - Consider adding “not-placebo-controlled” in parentheses. This was added. … Thus if the majority of sample came from a low risk of bias trial, the ROB domain in the SOE rating … Consider separate sections for placebo-controlled and no treatment trials. … phases” should be “was conducted in two randomized phases” This change has been made. … Peer reviewer #6 Discussion Could make more explicit that people that tolerate treatment were randomized

1186. Disposition of Comments Report for Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
      September 25, 2013 - This is reflected in the assessment of appropriate ROB items that were scored separately (e.g., randomized … clinical trial data is currently lacking. … There has been a call for a large randomized trial to evaluate the utility of platelet function testing … ES-22: In CURE, we did find an effect modification for GOF alleles. 4) Why no meta-analysis of randomized … Especially the need for a prospective randomized trial to assess whether alternative therapy based on

1187. Computerized Definitions Showed High Positive Predictive Values for Identifying Reasons for Hospitalizations in a Medicaid Population with Rheumatoid Arthritis (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-hospitalizations_research.pdf
      October 01, 2008 - with adverse events such as serious infections and congestive heart failure.3-6 Available clinical trial … Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized, controlled … trial.

1188. Disposition of Comments for CER 166 Calcineurin Inhibitors (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/calcineurin-inhibitor_disposition-comments.pdf
      March 15, 2016 - In addition to RCTs, we also included non-randomized prospective and retrospective comparative trials … Introduction Page 3, Lines 23-24: the increased access to transplantation for individuals with well-controlled … Global Development Medical Affairs, Americas Results • Asserting improved patient outcomes based on randomized … controlled trials (RCTs) reporting only one or two year results and oftentimes lacking biopsy data … A comparative, randomized trial of concentration- controlled sirolimus combined with reduced-dose tacrolimus

1189. Draft Comparative Effectiveness Review Appendicies (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_appendixes.pdf
      April 01, 2005 - Controlled Trials/ 38577 A-1 Appendix A. … controlled trial.pt. 204593 38 clinical trial.pt. 412355 39 controlled clinical trials/ 2929 40 ( … clin$ adj trial$).tw. 88180 41 ((singl$ or doubl$ or trebl$ or tripl$) adj (blind$ or mask$)).tw. 79196 … controlled trial Non-randomized comparative trial Prospective cohort (pre-post, single arm) Retrospective … • The randomized trial of surgical versus medical treatment, found that demographic factors did

1190. Layout 1 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
      April 01, 2007 - Registries are a valuable complement to randomized controlled trials in determining real-world outcomes … Defining Quality A definition of “quality” for registries was adapted from a definition developed for randomized … controlled trials; the term is used to refer to the confidence that the design, conduct, and analysis … of the trial or registry can be shown to protect against bias (systematic error) and errors in inference—that

1191. Disposition of Comments_Comparative Effectiveness Review No. 246: Management of High-Need, High-Cost Patients: A "Best Fit" Framework Synthesis, Realist Review, and Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/hnhc-disposition-comments.pdf
      October 29, 2021 - One, the CareMore randomized controlled trial, was included in the update.

1192. Crosscutting-Horizon-Scan-High-Impact-1412 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1412.pdf
      December 01, 2014 - The system was studied in a randomized controlled trial that compared propofol-mediated sedation delivered … In this trial, Pambianco et al. reported that patients undergoing Sedasys-mediated propofol sedation … second such bolus for 90 seconds.8 Clinical trials: The Sedasys system was studied in an open-label, randomized … controlled trial conducted to support a premarket approval application to FDA.9 In this trial, 1,000 … Computer-assisted personalized sedation for upper endoscopy and colonoscopy: a comparative, multicenter randomized

1193. Glaucoma-Screening Surveillance (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_surveillance.pdf
      January 01, 2013 - Evidence From Systematic Reviews A systematic review of randomized trials of screening modalities … "scanning laser polarimetry"[tiab]) AND ("Cohort Studies"[Mesh] OR "Case-Control Studies"[Mesh] OR randomized … controlled trial [pt] OR controlled clinical trial [pt] OR randomized [tiab] OR placebo [tiab] OR drug … exam for APD was 9.1%, specificity 99.3% IOP Measurement Scuderi 201014 Italy Non-randomized … Evidence From Systematic Reviews A systematic review of randomized trials of screening modalities

1194. Disposition of Comments Report for Childhood Obesity Prevention Programs: A Comparative Effectiveness Review and Meta-Analysis (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/obesity-child_disposition-comments.pdf
      June 10, 2013 - methods described in this report guidance. 106 TEP 1 Methods Since many school-based studies are randomized … A randomized controlled trial of culturally tailored dance and reducing screen time to prevent weight … Two-year follow-up results for Hip-Hop to Health Jr.: a randomized controlled trial for overweight … Were multiple comparisons appropriately controlled for? … Obesity Prevention Effectiveness Trial: postintervention results.

1195. Disposition of Comments Report for The Clinical Utility of Fractional Exhaled Nitric Oxide (FeNO) in Asthma Management (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-197-fractional-exhaled-nitric-oxide-disposition-comments.pdf
      December 20, 2017 - Typically adherence studies are not conducive to randomized controlled double blind studies, therefore … 20Value%20Proposition%20White%20Paper%20- %20Circassia%202017.pdf The reviewer’s comment about randomized … adherence being not conducive for evaluating adherence is incorrect (in fact, there are numerous randomized … (continued) Pavord 2012: the aim of this trial is to evaluate the effectiveness of Mepolizumab

1196. Mrsa-Screening-2010 Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/mrsa-screening-2010_executive.pdf
      January 01, 2010 - Data Sources and Selection MEDLINE® was searched from January 1, 1990, through March 30, 2012, for randomized … Embase® was searched from January 1, 1990, to March 30, 2012, for randomized controlled trials (RCTs … The Cochrane Controlled Trials Register was searched without date restriction using the same search … The gray literature was also searched, including databases with regulatory information, clinical trial … In this approach, rather than randomizing individual patients, wards or units are randomized to the

1197. Nonopioid Pharmacologic Treatments for Chronic Pain: Appendix E (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-ape_0.xlsx
      August 08, 2017 - Neuropathic Pain Author, Year Country Trial Name Quality Rating Type(s) of Pain Demographics Other Population … Characteristics N Randomized N Analyzed Intervention Duration (weeks) Funding Source Arezzo, 2008 U.S … Fibromyalgia Author, Year Country Trial Name Quality Rating Type(s) of Pain Demographics Other Population … Inflammatory Arthritis Author, Year Country Trial Name Quality Rating Type(s) of Pain Demographics Other … controlled trials; RD = risk difference; RR = rate ratio; SMD: standardized mean difference; tNSAID

1198. Untitled (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/suicide-prevention_research-protocol.pdf
      December 23, 2015 - Methods for synthesizing findings on moderation effects across multiple randomized trials. … Prevention of Suicide in Primary Care Elderly: Collaborative Trial (PROSPECT) Prevention of Suicide … in Primary Care Elderly: Collaborative Trial (PROSPECT) aims to prevent suicide among older primary … [pt] 6 “Non-randomized”[tiab] 7 Nonrandomized[tiab] 8 cohort[tiab] 9 “next study”[tiab] 10 … ; Not convicted: Dismissed/Bench/Jury Trial; Prison; Probation only; Fine only; and, Suspended sentence

1199. Template for Reports Developed (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-nomination_methods.pdf
      November 01, 2012 - If very few controlled trials are found or for topics that are not appropriate for controlled trials … Decisions about Effectiveness; PICO = populations, interventions, comparators, and outcomes; RCT = randomized … controlled trial The final step in completing the topic brief is assigning a team recommendation for … AHRQ = Agency for Healthcare Research and Quality; MRI = magnetic resonance imaging; RCT = randomized … controlled trial 16 Stakeholder Engagement Table 5 shows the points of stakeholder engagement

1200. Diabetes Mellitus (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_2012-12-10.pdf
      January 01, 2012 - to be completed in September 2011, but the National Clinical Trials database listed the trial as … Extended-release exenatide is a controlled-release, once-weekly formulation delivered by subcutaneous … Another research expert noted that another clinical trial compared this intervention to behavior and … In October 2012, the manufacturer stated plans to commence a phase III trial in January 2013, having … completed analysis of phase II trial results to determine an optimal dosing regimen for the planned