-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_appendixes.pdf
April 01, 2005 - Controlled Trials/ 38577
A-1
Appendix A. … controlled trial.pt. 204593
38 clinical trial.pt. 412355
39 controlled clinical trials/ 2929
40 ( … clin$ adj trial$).tw. 88180
41 ((singl$ or doubl$ or trebl$ or tripl$) adj (blind$ or mask$)).tw. 79196 … controlled trial
Non-randomized comparative trial
Prospective cohort (pre-post,
single arm)
Retrospective … • The randomized trial of
surgical versus medical
treatment, found that
demographic factors did
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-hospitalizations_research.pdf
October 01, 2008 - with
adverse events such as serious infections and congestive heart failure.3-6 Available clinical trial … Combination of infliximab and methotrexate
therapy for early rheumatoid arthritis: a
randomized, controlled … trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/calcineurin-inhibitor_disposition-comments.pdf
March 15, 2016 - In addition to RCTs, we also
included non-randomized
prospective and
retrospective comparative
trials … Introduction Page 3, Lines 23-24: the increased access to
transplantation for individuals with well-controlled … Global Development
Medical Affairs,
Americas
Results • Asserting improved patient outcomes based on
randomized … controlled trials (RCTs) reporting only
one or two year results and oftentimes lacking
biopsy data … A
comparative, randomized trial of concentration-
controlled sirolimus combined with reduced-dose
tacrolimus
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiotherapy-proton-beam_research.pdf
May 01, 2012 - research applications
since the 1950s and entered clinical practice in the United States
in 1990.1
No randomized … controlled trials and only a few well-conducted
cohort studies have compared proton beam radiation … A requirement (for some indications) that
the patient be treated as part of a clinical
trial.
4. … Dose-response in ra-
diotherapy for localized prostate cancer: results of the Dutch Multicenter
Randomized … Phase III Trial comparing 68 Gy of radiotherapy with 78
Gy.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth-future_research.pdf
August 09, 2012 - were identified by searching
Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled … were identified by searching Cochrane Database of Systematic Reviews, Cochrane Central
Register of Controlled … research, how much is already known about the topic in question, and the desired balance
between a controlled … interviews of
patients
• Surveys of patients and
providers
• Development of decision
aids
• Randomized … Focus groups/interviews
• Surveys of patients,
clinicians, administrators,
liability companies
• Randomized
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mrsa-screening-2010_executive.pdf
January 01, 2010 - Data Sources and Selection
MEDLINE® was searched from January 1, 1990, through
March 30, 2012, for randomized … Embase® was searched from January
1, 1990, to March 30, 2012, for randomized controlled
trials (RCTs … The Cochrane
Controlled Trials Register was searched without date
restriction using the same search … The gray literature was also searched,
including databases with regulatory information, clinical
trial … In this approach, rather
than randomizing individual patients, wards or units are
randomized to the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/undescended-testicle_research-protocol.pdf
September 02, 2011 - literature related to nonhuman subjects, and publications not
resulting from some form of clinical trial … For randomized controlled trials, the Cochrane Collaboration’s tool for
assessing risk of bias will … country, city, state) and time period, population description, sample size, and study type
(e.g., randomized … controlled trial, prospective observational study, etc.).
11
Source: www.effectivehealthcare.ahrq.gov
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
September 25, 2013 - This is reflected in the assessment of
appropriate ROB items that were scored separately (e.g.,
randomized … clinical trial data is currently
lacking. … There has been a call for a large randomized trial to evaluate
the utility of platelet function testing … ES-22: In CURE, we did find an effect modification for GOF
alleles.
4) Why no meta-analysis of randomized … Especially the need for a prospective randomized trial to
assess whether alternative therapy based on
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/obesity-child_disposition-comments.pdf
June 10, 2013 - methods
described in this report guidance.
106 TEP 1 Methods Since many school-based studies are
randomized … A randomized controlled
trial of culturally tailored dance and reducing
screen time to prevent weight … Two-year
follow-up results for Hip-Hop to Health Jr.: a
randomized controlled trial for overweight … Were multiple comparisons appropriately
controlled for? … Obesity Prevention
Effectiveness Trial: postintervention results.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_surveillance.pdf
January 01, 2013 - Evidence From Systematic Reviews
A systematic review of randomized
trials of screening modalities … "scanning laser polarimetry"[tiab]) AND ("Cohort Studies"[Mesh] OR "Case-Control
Studies"[Mesh] OR randomized … controlled trial [pt] OR controlled clinical trial [pt] OR
randomized [tiab] OR placebo [tiab] OR drug … exam for APD was
9.1%, specificity
99.3%
IOP
Measurement
Scuderi 201014
Italy
Non-randomized … Evidence From Systematic Reviews
A systematic review of randomized trials of
screening modalities
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
April 01, 2007 - Registries are a valuable complement to randomized
controlled trials in determining real-world outcomes … Defining Quality
A definition of “quality” for registries was adapted
from a definition developed for randomized … controlled trials; the term is used to refer to the
confidence that the design, conduct, and analysis … of
the trial or registry can be shown to protect against
bias (systematic error) and errors in inference—that
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-monitoring-systems-appendix-c.xlsx
January 01, 2024 - controlled trial
RR risk ratio
RRS rapid response system
RRT rapid response team
SD standard deviation … A controlled before and after study. … Comparison of Two Pediatric Early Warning Systems: A Randomized Trial. … controlled pilot trial. … trial, non-randomized Academic 1 Adult 2740 Surgical and Medical NR NR
Miles, 2023 No NR 14 months
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-197-fractional-exhaled-nitric-oxide-disposition-comments.pdf
December 20, 2017 - Typically adherence studies are
not conducive to randomized controlled double blind
studies, therefore … 20Value%20Proposition%20White%20Paper%20-
%20Circassia%202017.pdf
The reviewer’s
comment about
randomized … adherence being not
conducive for
evaluating adherence
is incorrect (in fact,
there are numerous
randomized … (continued)
Pavord 2012: the aim
of this trial is to
evaluate the
effectiveness of
Mepolizumab
-
effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1412.pdf
December 01, 2014 - The system was studied in a randomized controlled trial that compared propofol-mediated
sedation delivered … In this trial,
Pambianco et al. reported that patients undergoing Sedasys-mediated propofol sedation … second
such bolus for 90 seconds.8
Clinical trials: The Sedasys system was studied in an open-label, randomized … controlled trial
conducted to support a premarket approval application to FDA.9 In this trial, 1,000 … Computer-assisted personalized sedation for upper
endoscopy and colonoscopy: a comparative,
multicenter randomized
-
effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_2012-12-10.pdf
January 01, 2012 - to
be completed in September 2011, but the National Clinical Trials database listed the trial as … Extended-release exenatide is a controlled-release, once-weekly formulation delivered
by subcutaneous … Another research expert
noted that another clinical trial compared this intervention to behavior and … In October 2012, the manufacturer stated plans to commence a phase III
trial in January 2013, having … completed analysis of phase II trial results to determine an optimal
dosing regimen for the planned
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-nomination_methods.pdf
November 01, 2012 - If very few controlled trials are found or for topics that are
not appropriate for controlled trials … Decisions about
Effectiveness; PICO = populations, interventions, comparators, and outcomes; RCT = randomized … controlled trial
The final step in completing the topic brief is assigning a team recommendation for … AHRQ = Agency for Healthcare Research and Quality; MRI = magnetic resonance imaging; RCT = randomized … controlled trial
16
Stakeholder Engagement
Table 5 shows the points of stakeholder engagement
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/suicide-prevention_research-protocol.pdf
December 23, 2015 - Methods for synthesizing findings on
moderation effects across multiple
randomized trials. … Prevention of Suicide in
Primary Care Elderly:
Collaborative Trial
(PROSPECT)
Prevention of Suicide … in Primary Care Elderly: Collaborative Trial (PROSPECT) aims to
prevent suicide among older primary … [pt]
6 “Non-randomized”[tiab]
7 Nonrandomized[tiab]
8 cohort[tiab]
9 “next study”[tiab]
10 … ; Not convicted: Dismissed/Bench/Jury Trial; Prison; Probation only; Fine only; and,
Suspended sentence
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hnhc-disposition-comments.pdf
October 29, 2021 - One, the CareMore
randomized controlled trial, was included in the update.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bundled-payments-quality-effects_research-protocol.pdf
June 23, 2011 - [tiab]
AND
payment[tiab] OR finance*[tiab] OR reimburse*[tiab] OR incentive*[tiab]
AND
trial … The following data will be abstracted from included studies:
Trial name. … Abbreviations: EPC = Evidence-based Practice Center; RCT = randomized controlled trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rural-telehealth-amended-protocol.pdf
February 25, 2021 - countries)
7
Include Exclude
Study types and
designs
KQ1: Comparative studies including trial … Information relevant for assessing applicability will
include the number of patients randomized/eligible … Controlled trials and observational
studies will be assessed using a priori established criteria consistent … If meta-
analysis is performed, randomized controlled trials will be analyzed separately from observational … currently states: Information
relevant for assessing
applicability will include the
number of patients
randomized