Results

Total Results: 1,523 records

Showing results for "randomized controlled trial".

1161. women-hiv-protocol-160301 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/women-hiv_research-protocol.pdf
      March 01, 2016 - design that allows, even under strong assumptions, estimation of the impact of a resource, including randomized … trials, non-randomized comparisons of cohorts, and before-after studies. … Any comparative design is eligible including randomized trials, nonrandomized comparisons of cohorts … the effectiveness and safety of treatments for co-occurring diseases or risk factors, eligible are randomized

1162. Improving Health Care and Palliative Care for Advanced and Serious Illness Disposition of Comments Report (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/quality-gap-palliative-hospice_disposition-comments.pdf
      October 01, 2012 - Published Online: October 2012. 8 Comment# Commentator & Affiliation Section Comment Response randomized … trials, which did not capture many issues of methodologic quality within non-randomized quality improvement … trials, which did not capture many issues of methodologic quality within non-randomized quality improvement … A CQI study could be an RCT, but it would need to be cluster-randomized design. … The Temel study in the NEJM was done at a single site essentially as a randomized Phase II trial.

1163. S66 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/s66.pdf
      October 01, 2007 - DISCUSSION Randomized clinical trials have consistently shown the efficacy of biologic DMARDs in controlling … A controlled clinical trial. Arthritis Rheum. 1985;28:721–730. 5. … A 48-week double-blind, prospective, placebo- controlled study. … Anti-Tumor Ne- crosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. … Why randomized controlled clinical trials do not depict accurately long-term outcomes in rheumatoid arthritis

1164. Suppl-2-User-Guide-To-Ocer 130129 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/suppl-2-user-guide-to-ocer_130129.pdf
      January 01, 2011 - In an ideal randomized experiment, treatment assignment is independent of the counterfactual outcomes … trial, the outcome experience had the entire population been treated (Pr[Ya=1=1]) is equal to the … To simplify, consider a randomized trial of antihypertensive treatments (CCB or other) and the outcome … Treatment (A) is randomized. … Subjects randomized to CCBs (A=1) are more likely to drop out due to adverse drug effects.

1165. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-liver-metastases-therapies_research-protocol.pdf
      September 27, 2012 - Source: www.effectivehealthcare.ahrq.gov Published Online: September 27, 2012 equipoise and limited randomized … trial data comparing liver-directed therapies22, 23 leaves uncertainty around which techniques, either … Criteria for Inclusion/Exclusion of Studies in the Review We will include randomized controlled trials … • MEDLINE® • EMBASE® • Cochrane Controlled Trials Register http://www.effectivehealthcare.ahrq.gov … Phase III trial comparing protracted intravenous fluorouracil infusion alone or with yttrium-90 resin

1166. Frameworks for Determining Research Gaps During Systematic Reviews (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-research-steps-framework_research.pdf
      June 01, 2011 - If no recent reviews of a specific topic were found, a search was made for randomized controlled trials … controlled trial, STI=sexually transmitted infection … controlled trial (RCT) for each topic.5 Research gaps/needs were identified as areas of insufficient … Controlled Trial RFA Request For Applications RTI Research Triangle Institute SBU The Swedish Council … controlled trial, RTI=Research Triangle Institute, TEP=technical expert panel, UNC=university of North

1167. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/therapies-for-autism-spectrum-disorder-2-9-2010.pdf
      January 01, 2010 - review found methodological weaknesses in systematic reviews of psychosocial interventions.7 While controlled … languages English only Admissible evidence (study design and other criteria) Admissible designs • Controlled … country, city, state) and time period, population description, sample size, and study type (e.g., randomized … controlled trial, prospective observational study, etc).

1168. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism_research-protocol.pdf
      December 09, 2009 - review found methodological weaknesses in systematic reviews of psychosocial interventions.7 While controlled … languages English only Admissible evidence (study design and other criteria) Admissible designs • Controlled … country, city, state) and time period, population description, sample size, and study type (e.g., randomized … controlled trial, prospective observational study, etc).

1169. Functional-Limitations-Horizon-Scan-High-Impact-1306 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/functional-limitations-horizon-scan-high-impact-1306.pdf
      June 01, 2013 - maintenance dosage of 240 mg twice a day, orally.14 Clinical trials: In two multicenter phase III, randomized … Clinical trials: In two multicenter, double-blind, randomized controlled trials, the effects of icatibant … Placebo- controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis. … Placebo- controlled phase 3 study of oral BG-12 or glatiramer in multiple sclerosis. … Results from FAST-3: a phase III randomized, double-blind, placebo-controlled, multicenter study

1170. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-nonsurgical-therapies_research-protocol.pdf
      February 22, 2012 - Study Selection Criteria We will seek to include only comparative studies, preferably randomized … controlled trials (RCTs), but also nonrandomized comparative studies (including case-control and cohort … librarian for citations from January 1995 through December 2011: • MEDLINE® • EMBASE® • Cochrane Controlled

1171. Evaluating Practices and Developing Tools for Comparative Effectiveness Reviews of Diagnostic Test Accuracy: Methods for the Joint Meta-Analysis of Multiple Tests (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/diagnostic-tests-accuracy_research.pdf
      January 01, 2013 - sufficient to evaluate a diagnostic test, and reliably identifies trisomy 18 and trisomy 13 when do we need randomized … Using the principles of randomized controlled trial 17. Bromley B, Lieberman E, Benacerraf BR. … Modeling between-trial variance structure in mixed treatment comparisons. Biostatistics.

1172. Disposition of Comments Report for Otitis Media With Effusion (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/ear-infection_disposition-comments.pdf
      May 04, 2013 - The studies that the reviewer mentions are randomized by child and by ear. … There is a single randomized controlled trial (RCT) by Gates in 1987 that showed in a very select group … This was not simply a trial comparing adenoidectomy plus myringotomy vs. adenoidectomy plus tubes. … controlled trials (RCTs), nonrandomized controlled trials and cohort studies.” … It is directly contradicted by the Paradise clinical trial reported in the NJM and elsewhere and it

1173. Disposition of Comments_Systematic Review: Breastfeeding and Health Outcomes for Infants and Children (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-disposition-comments.pdf
      March 31, 2025 - of breastfeeding can be, and this was done in the PROBIT trial. … All of the observational analyses from the PROBIT trial are included in our review. … insufficient evidence to draw conclusions about the relationship with food allergies and no well-controlled … We also agree that randomized clinical trials, including cluster randomized trials, can help to understand … Given that randomized controlled trials (RCTs) are not feasible in breastfeeding research, we encourage

1174. Mixed MethodsReview -Integrating Palliative Care with Chronic Disease Management in Ambulatory Care (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/palliative-care-research-amended-protocol.pdf
      November 21, 2019 - controlled trials • Non-randomized studies with concurrent or historical controls • Articles … following databases for primary quantitative studies: PubMed, CINAHL, and the Cochrane Central Register of Controlled … For nonrandomized studies, we will use the Cochrane Risk of Bias Assessment Tool for Non-Randomized … Randomized controlled trials and nonrandomized studies will be analyzed separately. … dichotomous outcomes are presented, we will calculate a pooled effect estimate of relative risk between trial

1175. Radiotherapy-Proton-Beam Research (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiotherapy-proton-beam_research.pdf
      May 01, 2012 - research applications since the 1950s and entered clinical practice in the United States in 1990.1 No randomized … controlled trials and only a few well-conducted cohort studies have compared proton beam radiation … A requirement (for some indications) that the patient be treated as part of a clinical trial. 4. … Dose-response in ra- diotherapy for localized prostate cancer: results of the Dutch Multicenter Randomized … Phase III Trial comparing 68 Gy of radiotherapy with 78 Gy.

1176. Vaginal Birth After Cesarean: Developing and Prioritizing a Future Research Agenda (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth-future_research.pdf
      August 09, 2012 - were identified by searching Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled … were identified by searching Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled … research, how much is already known about the topic in question, and the desired balance between a controlled … interviews of patients • Surveys of patients and providers • Development of decision aids • Randomized … Focus groups/interviews • Surveys of patients, clinicians, administrators, liability companies • Randomized

1177. Topic-Brief1-Care-Coordination (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief1-care-coordination.pdf
      April 01, 2021 - multidisciplinary Enhanced Recovery After Surgery (ERAS) model in post- pancreatectomy patients,3 but identified no randomized … • One other meta-analysis (not in the review of reviews) also identified no randomized trials and … ERAS model with usual care and three low quality uncontrolled ERAS cohort studies, but identified no randomized … Although we identified 26 systematic reviews (17 in a review of reviews and 9 additional), no randomized … It evaluated the ERAS protocol in persons with post-surgical pain but identified no randomized trials

1178. Topic-Brief1-Care-Coordination (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief1-care-coordination.pdf
      April 01, 2021 - multidisciplinary Enhanced Recovery After Surgery (ERAS) model in post- pancreatectomy patients,3 but identified no randomized … • One other meta-analysis (not in the review of reviews) also identified no randomized trials and … ERAS model with usual care and three low quality uncontrolled ERAS cohort studies, but identified no randomized … Although we identified 26 systematic reviews (17 in a review of reviews and 9 additional), no randomized … It evaluated the ERAS protocol in persons with post-surgical pain but identified no randomized trials

1179. Executive Summary_Comparative Effectiveness Review No. 263: Management of Postpartum Hypertensive Disorders of Pregnancy (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-263-postpartum-hypertensive-pregnancy-executive-summary.pdf
      May 01, 2023 - Our searches targeted comparative studies (i.e., randomized controlled trials [RCTs] and nonrandomized

1180. Digestible Carbohydrate Intake and Maternal-Infant Outcomes: Appendix D Tables (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-appendix-d.xlsx
      January 01, 2019 - . 70% Smoked during first trimester: 0.8% vs. 5.7% Dietary counseling (from Piirainen 2007: further randomized … age, smoking during pregnancy, 2-h OGTT plasma glucose value, energy intake, offspring sex The TOP trial … ) Australia NR Inclusion: Overweight and obese pregnant women with complete data enrolled in SPRING trial … Data System for Research NR not reported NS not significant OGTT oral glucose tolerance test RCT randomized … controlled trial SD standard deviation SE standard error SPRING Study of Probiotic IN Gestational