Results

Total Results: 1,524 records

Showing results for "randomized controlled trial".

1161. Rapid Evidence Product_Assisted Home Dialysis in the United States: New Interest in an Old Idea (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/home-dialysis-ESKD-rapid-research.pdf
      April 01, 2025 - Facilities and Clinicians Treating Patients With End-stage Kidney Disease and Use of Home Dialysis: A Randomized … Clinical Trial. … clinical trial or randomized controlled trial).pt. or (control or controls or controlled or random* … or Comparative Study/ or Controlled Before- After Studies/ or Cross-Sectional Studies/ or exp Evaluation … , Randomized Controlled Trial (19) S9 TI S3 AND S6 Limiters - Published Date: 20180301-20230731; English

1162. Undescended-Testicle Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
      December 01, 2012 - For randomized controlled trials (RCTs), we used the Cochrane Risk of Bias tool;6 for cohort studies … Short-term testicular descent in two-arm, randomized, placebo-controlled studies Study N Length of … controlled trial 11 body of epidemiologic data and data from noncomparative studies to which we … In order for this comparison to be valid, the trial would also need to control for location within … Such a trial would be ethical, as primary orchiopexy would not be the focus of the study and would

1163. Improving Health Care and Palliative Care for Advanced and Serious Illness Disposition of Comments Report (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/quality-gap-palliative-hospice_disposition-comments.pdf
      October 01, 2012 - Published Online: October 2012. 8 Comment# Commentator & Affiliation Section Comment Response randomized … trials, which did not capture many issues of methodologic quality within non-randomized quality improvement … trials, which did not capture many issues of methodologic quality within non-randomized quality improvement … A CQI study could be an RCT, but it would need to be cluster-randomized design. … The Temel study in the NEJM was done at a single site essentially as a randomized Phase II trial.

1164. Stem-Cell-Children Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_executive.pdf
      February 01, 2012 - For example, the literature on the use of HSCT in hematologic malignancies is robust, including randomized … controlled trials that date back 20 years, and its practice is supported by evidence-based guidelines … Sources and Study Selection Electronic databases searched were MEDLINE®, Embase®, and the Cochrane Controlled … Randomized controlled trials were rare for any of the indications included in this systematic review … For inherited metabolic diseases, controlled trials with sufficient followup are needed to evaluate

1165. CER 220: Disposition of Comments Report for Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-disposition-comments-analgesics-prehospital-setting.pdf
      September 03, 2019 - study for opioids or ketamine in to the review, assuming the pain had to be at least moderate for a trial … controlled trial. … In EMS, accountability for controlled substances has a particular set of challenges, as does deploying … Example: Prehospital Analgesia with Intranasal Ketamine (PAIN-K): A Randomized Double-Blind Trial in … The inclusion of mainly randomized controlled trials is rigorous.

1166. Glaucoma-Screening Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_executive.pdf
      April 01, 2012 - Data Sources and Selection We included randomized controlled trials (RCTs), quasi- randomized controlled … and quasi-randomized trials. … controlled trials as the highest level of evidence, followed by comparative observational studies. … controlled trial of glaucoma screening would be the optimal study design, as an RCT design would allow … assessment of stereoscopic optic disc photographs for glaucoma: the European Optic Disc Assessment Trial

1167. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/fetal-surgery_disposition-comments.pdf
      July 05, 2011 - In fact, the poorly conducted randomized clinical trial in the United States (100% prematurity, 100% … text to be more specific: 8 of 32 (25%) with recurrent pulmonary infections; and 25% with asthma controlled … has been put forth by theData Monitoring and Safety Committee of the BostonChildren‟s study, a well-controlled … We have strengthened information regarding the lack of randomized trials making direct comparisons … The Senat (Eurofoetus) trial randomized patients to either amnioreduction or laser PRIOR to any intervention

1168. Renal-Function Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-function_research-protocol.pdf
      June 13, 2013 - Long-term outcomes – All-cause mortality – ≥1 year MACE rates Type of study • We will include randomized … controlled trials and observational studies with a comparison group … the following databases for primary studies: MEDLINE®, EMBASE®, and the Cochrane Central Register of Controlled … anticipate the studies to be predominantly observational in nature, including post-hoc analyses of randomized … controlled trials that studied ACS interventions.

1169. Executive Summary_Comparative Effectiveness Review No. 263: Management of Postpartum Hypertensive Disorders of Pregnancy (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-263-postpartum-hypertensive-pregnancy-executive-summary.pdf
      May 01, 2023 - Our searches targeted comparative studies (i.e., randomized controlled trials [RCTs] and nonrandomized

1170. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-nonsurgical-therapies_research-protocol.pdf
      February 22, 2012 - Study Selection Criteria We will seek to include only comparative studies, preferably randomized … controlled trials (RCTs), but also nonrandomized comparative studies (including case-control and cohort … librarian for citations from January 1995 through December 2011: • MEDLINE® • EMBASE® • Cochrane Controlled

1171. Effectiveness of Screening and Treatment of Subclinical Hypothyroidism or Hyperthyroidism (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypothyroidism-hyperthyroidism-screening-treatment_disposition-comments.pdf
      February 01, 2012 - It is a controlled clinical trial. … This study was described as a controlled trial not a randomized controlled trial.

1172. Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacological Interventions (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/cer-236-maternal-fetal-child-outcomes-disposition-comments.pdf
      April 15, 2021 - Rather than using the vague term “trials”, it would be better to specify if this refers to randomized … controlled trials or other types of trials (e.g., non- randomized, non-controlled trials). … “Rates of loss of consciousness did not appear to vary by dose and were similar among women randomized … specific about the reasons that the evidence on harms of treatment is of low quality (e.g., poorly controlled … This now reads: “for both drugs, we found evidence bases with two or more randomized controlled trials

1173. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-liver-metastases-therapies_research-protocol.pdf
      September 27, 2012 - Source: www.effectivehealthcare.ahrq.gov Published Online: September 27, 2012 equipoise and limited randomized … trial data comparing liver-directed therapies22, 23 leaves uncertainty around which techniques, either … Criteria for Inclusion/Exclusion of Studies in the Review We will include randomized controlled trials … • MEDLINE® • EMBASE® • Cochrane Controlled Trials Register http://www.effectivehealthcare.ahrq.gov … Phase III trial comparing protracted intravenous fluorouracil infusion alone or with yttrium-90 resin

1174. Topic-Brief1-Care-Coordination (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief1-care-coordination.pdf
      April 01, 2021 - multidisciplinary Enhanced Recovery After Surgery (ERAS) model in post- pancreatectomy patients,3 but identified no randomized … • One other meta-analysis (not in the review of reviews) also identified no randomized trials and … ERAS model with usual care and three low quality uncontrolled ERAS cohort studies, but identified no randomized … Although we identified 26 systematic reviews (17 in a review of reviews and 9 additional), no randomized … It evaluated the ERAS protocol in persons with post-surgical pain but identified no randomized trials

1175. Topic-Brief1-Care-Coordination (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief1-care-coordination.pdf
      April 01, 2021 - multidisciplinary Enhanced Recovery After Surgery (ERAS) model in post- pancreatectomy patients,3 but identified no randomized … • One other meta-analysis (not in the review of reviews) also identified no randomized trials and … ERAS model with usual care and three low quality uncontrolled ERAS cohort studies, but identified no randomized … Although we identified 26 systematic reviews (17 in a review of reviews and 9 additional), no randomized … It evaluated the ERAS protocol in persons with post-surgical pain but identified no randomized trials

1176. Disposition of Comments Report for Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
      September 25, 2013 - This is reflected in the assessment of appropriate ROB items that were scored separately (e.g., randomized … clinical trial data is currently lacking. … There has been a call for a large randomized trial to evaluate the utility of platelet function testing … ES-22: In CURE, we did find an effect modification for GOF alleles. 4) Why no meta-analysis of randomized … Especially the need for a prospective randomized trial to assess whether alternative therapy based on

1177. Protocol Amendment - Safety of Vaccines 030413 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccines-safety-protocol-130325.pdf
      September 18, 2012 - rule out overt toxicity and identify potential toxic effects that might occur during the clinical trial … Investigational New Drug application must be submitted so that the FDA can monitor the safety of clinical trial … retrospective observational studies that compare vaccine recipients with an unvaccinated group, self-controlled … retrospective observational studies that compare vaccine recipients with an unvaccinated group, self-controlled

1178. Engaging-Caregivers-Appendix-B (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/engaging-caregivers-appendix-b.xlsx
      October 08, 2025 - Mean, Unless Specified) Patient Female % Caregiver Female % Race/Ethnicity (As Reported by Authors) N Randomized … training and time; framework development time; materials; registry for data collection and feedback Controlled … intensive care unit; LOS = length of stay; NR = not reported; PHQ-9 = Patient Health Questionnaire 9; RCT = randomized … controlled trial; RR = relative risk; SD = standard deviation; SMART = Substance Misuse in Adolescents

1179. Mrsa-Screening-2010 Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/mrsa-screening-2010_executive.pdf
      January 01, 2010 - Data Sources and Selection MEDLINE® was searched from January 1, 1990, through March 30, 2012, for randomized … Embase® was searched from January 1, 1990, to March 30, 2012, for randomized controlled trials (RCTs … The Cochrane Controlled Trials Register was searched without date restriction using the same search … The gray literature was also searched, including databases with regulatory information, clinical trial … In this approach, rather than randomizing individual patients, wards or units are randomized to the

1180. Disposition of Comments Report for Otitis Media With Effusion (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/ear-infection_disposition-comments.pdf
      May 04, 2013 - The studies that the reviewer mentions are randomized by child and by ear. … There is a single randomized controlled trial (RCT) by Gates in 1987 that showed in a very select group … This was not simply a trial comparing adenoidectomy plus myringotomy vs. adenoidectomy plus tubes. … controlled trials (RCTs), nonrandomized controlled trials and cohort studies.” … It is directly contradicted by the Paradise clinical trial reported in the NJM and elsewhere and it