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Showing results for "randomized controlled trial".

  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_research-protocol.pdf
    December 06, 2010 - evidence (study design and other criteria) Original research; eligible study designs include: • Randomizedcontrolled trials with a sample size ≥100 • Nonrandomized controlled trials • Observational studies
  2. effectivehealthcare.ahrq.gov/sites/default/files/cer-244-safety-of-vaccines.pdf
    May 25, 2021 - - controlled designs). … Evidence [Comment in pdf file on “The most frequent study designs identified in the update were randomized … followed by cohort studies (n=26), pre-post designs (n=12), case-control designs (n=9), and one non-randomizedcontrolled clinical trial, along with 13 others that used selfcontrol methods (either self- controlled … The data for autism comes from the clinical trial record for NCT01240746; this trial is the basis of
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_executive.pdf
    April 01, 2012 - Data Sources and Selection We included randomized controlled trials (RCTs), quasi- randomized controlled … and quasi-randomized trials. … controlled trials as the highest level of evidence, followed by comparative observational studies. … controlled trial of glaucoma screening would be the optimal study design, as an RCT design would allow … assessment of stereoscopic optic disc photographs for glaucoma: the European Optic Disc Assessment Trial
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hro-protocol.pdf
    January 01, 2023 - the primary reviewer will use the Cochrane Collaboration’s tool for assessing the risk of bias of randomizedcontrolled trials (RCTs) or the ROBINS-I tool for assessing the Risk Of Bias In Non-randomized Studies … performance bias, detection bias, attrition bias, reporting bias, and other bias.10 When assessing non-randomized
  5. effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1412.pdf
    February 01, 2015 - The largest clinical trial to date is scheduled to conclude in 2015. … In 2013, the Alzheimer’s Disease Cooperative Study registered the largest randomized, controlled trial … and neuroanatomy, is scheduled to conclude in February 2015.12 A large German clinical trial (n=90 … The latter cooperative sponsors the largest ongoing trial, a phase II/III trial investigating intranasal … Available: https://www.clinicaltrialsregister.eu/ctr- search/trial/2008-008555-41/DE/. 22.
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-disparities_research-protocol.pdf
    July 01, 2015 - Systematic Reviews; Humans; English; Adult: 19+ years 28 #19 Search (#11 AND #12) Filters: Clinical Trial … ; Randomized Controlled Trial; Humans; English; Adult: 19+ years 375 We will retrieve and review … Inclusion Exclusion Study design GQs 1, 2, and 4 § No limitations GQ 3 § Systematic reviews § Randomizedcontrolled trials § Nonrandomized controlled trials § Prospective and retrospective cohort studies
  7. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-child-adolesc-mental-health-grand-rounds.pptx
    May 22, 2025 - treatment study of >4 weeks Any study of evaluating a monitoring strategy Diagnostic accuracy study Controlled … We also identified 69 trial registrations through clinical trial registries. … Of the 65 included studies, 33 studies were randomized clinical trials (RCTs), 13 were comparative After … FFT Designed for bipolar youths. 1 trial found no differences for SI. … emerging biological treatments on suicide highlight a gap in the evidence base and a critical need for controlled
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/home-dialysis-ESKD-rapid-research.pdf
    April 01, 2025 - Facilities and Clinicians Treating Patients With End-stage Kidney Disease and Use of Home Dialysis: A Randomized … Clinical Trial. … clinical trial or randomized controlled trial).pt. or (control or controls or controlled or random* … or Comparative Study/ or Controlled Before- After Studies/ or Cross-Sectional Studies/ or exp Evaluation … , Randomized Controlled Trial (19) S9 TI S3 AND S6 Limiters - Published Date: 20180301-20230731; English
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-function_research-protocol.pdf
    June 13, 2013 - Long-term outcomes – All-cause mortality – ≥1 year MACE rates Type of study • We will include randomizedcontrolled trials and observational studies with a comparison group … the following databases for primary studies: MEDLINE®, EMBASE®, and the Cochrane Central Register of Controlled … anticipate the studies to be predominantly observational in nature, including post-hoc analyses of randomizedcontrolled trials that studied ACS interventions.
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/engaging-caregivers-appendix-b.xlsx
    May 29, 2025 - Mean, Unless Specified) Patient Female % Caregiver Female % Race/Ethnicity (As Reported by Authors) N Randomized … training and time; framework development time; materials; registry for data collection and feedback Controlled … intensive care unit; LOS = length of stay; NR = not reported; PHQ-9 = Patient Health Questionnaire 9; RCT = randomizedcontrolled trial; RR = relative risk; SD = standard deviation; SMART = Substance Misuse in Adolescents
  11. effectivehealthcare.ahrq.gov/sites/default/files/01_-arthritis_potential_high_impact_june_2012.pdf
    January 01, 2012 - The evidence base for PRP lacks large, blinded, prospective, randomized, controlled trials. … One open-label extension trial demonstrated durable responses to tofacitinib up to 36 months. … However, some of the experts stated that large, randomized, double-blind trials are needed to better … perspectives stated that PRP injections could gain larger acceptance if shown to be effective in randomized … In another clinical trial, patients in whom RA was diagnosed (n=1,070) were given tofacitinib 5 or
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/long-term-care-adults-future_research.pdf
    July 01, 2013 - controlled trials (RCTs) were identified. … controlled trial References 1. … controlled trials (RCTs) were identified. … For example, factors that affect the feasibility of conducting randomized controlled trials include … controlled trial 20
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-bias_methods.pdf
    July 01, 2012 - Categorizing individual studies into general quality classes* Category Application to RandomizedControlled Trials Application to Medical Test Performance Studies Low.
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_executive.pdf
    February 01, 2012 - For example, the literature on the use of HSCT in hematologic malignancies is robust, including randomizedcontrolled trials that date back 20 years, and its practice is supported by evidence-based guidelines … Sources and Study Selection Electronic databases searched were MEDLINE®, Embase®, and the Cochrane ControlledRandomized controlled trials were rare for any of the indications included in this systematic review … For inherited metabolic diseases, controlled trials with sufficient followup are needed to evaluate
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-disposition-comments-analgesics-prehospital-setting.pdf
    September 03, 2019 - study for opioids or ketamine in to the review, assuming the pain had to be at least moderate for a trialcontrolled trial. … In EMS, accountability for controlled substances has a particular set of challenges, as does deploying … Example: Prehospital Analgesia with Intranasal Ketamine (PAIN-K): A Randomized Double-Blind Trial in … The inclusion of mainly randomized controlled trials is rigorous.
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/women-hiv_research-protocol.pdf
    March 01, 2016 - design that allows, even under strong assumptions, estimation of the impact of a resource, including randomized … trials, non-randomized comparisons of cohorts, and before-after studies. … Any comparative design is eligible including randomized trials, nonrandomized comparisons of cohorts … the effectiveness and safety of treatments for co-occurring diseases or risk factors, eligible are randomized
  17. S66 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s66.pdf
    October 01, 2007 - DISCUSSION Randomized clinical trials have consistently shown the efficacy of biologic DMARDs in controlling … A controlled clinical trial. Arthritis Rheum. 1985;28:721–730. 5. … A 48-week double-blind, prospective, placebo- controlled study. … Anti-Tumor Ne- crosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. … Why randomized controlled clinical trials do not depict accurately long-term outcomes in rheumatoid arthritis
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-267-adhd-disposition-comments.pdf
    March 25, 2024 - Double-Blind Placebo-Controlled Randomized Clinical Trial of Neurofeedback for Attention- Deficit/Hyperactivity … Neurofeedback for ADHD: 25-month follow-up of double-blind randomized controlled trial (2023). … EEG neurofeedback for ADHD: double-blind sham-controlled randomized pilot feasibility trial. … Double-blind placebo-controlled randomized clinical trial of neurofeedback for attention- deficit/hyperactivity … A randomized placebo- controlled trial of electroencephalographic (EEG) neurofeedback in children with
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/fetal-surgery_disposition-comments.pdf
    July 05, 2011 - In fact, the poorly conducted randomized clinical trial in the United States (100% prematurity, 100% … text to be more specific: 8 of 32 (25%) with recurrent pulmonary infections; and 25% with asthma controlled … has been put forth by theData Monitoring and Safety Committee of the BostonChildren‟s study, a well-controlled … We have strengthened information regarding the lack of randomized trials making direct comparisons … The Senat (Eurofoetus) trial randomized patients to either amnioreduction or laser PRIOR to any intervention
  20. effectivehealthcare.ahrq.gov/sites/default/files/cer-236-maternal-fetal-child-outcomes-disposition-comments.pdf
    April 15, 2021 - Rather than using the vague term “trials”, it would be better to specify if this refers to randomizedcontrolled trials or other types of trials (e.g., non- randomized, non-controlled trials). … “Rates of loss of consciousness did not appear to vary by dose and were similar among women randomized … specific about the reasons that the evidence on harms of treatment is of low quality (e.g., poorly controlled … This now reads: “for both drugs, we found evidence bases with two or more randomized controlled trials

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