-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_research-protocol.pdf
December 06, 2010 - evidence (study
design and other
criteria)
Original research; eligible study designs include:
• Randomized … controlled trials with a sample size
≥100
• Nonrandomized controlled trials
• Observational studies
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-244-safety-of-vaccines.pdf
May 25, 2021 - -
controlled designs). … Evidence
[Comment in pdf file on “The most
frequent study designs identified in the
update were randomized … followed by cohort
studies (n=26), pre-post designs
(n=12), case-control designs (n=9),
and one non-randomized … controlled
clinical trial, along with 13 others that
used selfcontrol methods (either self-
controlled … The data for autism comes from the
clinical trial record for NCT01240746;
this trial is the basis of
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_executive.pdf
April 01, 2012 - Data Sources and Selection
We included randomized controlled trials (RCTs), quasi-
randomized controlled … and quasi-randomized
trials. … controlled trials as the highest level of
evidence, followed by comparative observational studies. … controlled trial of glaucoma screening
would be the optimal study design, as an RCT design
would allow … assessment
of stereoscopic optic disc photographs for glaucoma: the European
Optic Disc Assessment Trial
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hro-protocol.pdf
January 01, 2023 - the
primary reviewer will use the Cochrane Collaboration’s tool for assessing the risk of bias of
randomized … controlled trials (RCTs) or the ROBINS-I tool for assessing the Risk Of Bias In
Non-randomized Studies … performance bias, detection bias, attrition bias, reporting bias, and other bias.10 When
assessing non-randomized
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effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1412.pdf
February 01, 2015 - The largest clinical trial to date is scheduled to conclude in 2015. … In 2013, the Alzheimer’s Disease Cooperative Study registered the largest randomized,
controlled trial … and neuroanatomy, is scheduled to conclude in
February 2015.12 A large German clinical trial (n=90 … The latter cooperative sponsors the largest ongoing trial, a phase II/III trial
investigating intranasal … Available:
https://www.clinicaltrialsregister.eu/ctr-
search/trial/2008-008555-41/DE/.
22.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-disparities_research-protocol.pdf
July 01, 2015 - Systematic Reviews; Humans; English; Adult: 19+ years 28
#19 Search (#11 AND #12) Filters: Clinical Trial … ; Randomized Controlled Trial; Humans;
English; Adult: 19+ years
375
We will retrieve and review … Inclusion Exclusion
Study design GQs 1, 2, and 4
§ No limitations
GQ 3
§ Systematic reviews
§ Randomized … controlled trials
§ Nonrandomized controlled trials
§ Prospective and retrospective cohort studies
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-child-adolesc-mental-health-grand-rounds.pptx
May 22, 2025 - treatment study of >4 weeks Any study of evaluating a monitoring strategy
Diagnostic accuracy study Controlled … We also identified 69 trial registrations through clinical trial registries. … Of the 65 included studies, 33 studies were randomized clinical trials (RCTs), 13 were comparative
After … FFT
Designed for bipolar youths.
1 trial found no differences for SI. … emerging biological treatments on suicide highlight a gap in the evidence base and a critical need for controlled
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/home-dialysis-ESKD-rapid-research.pdf
April 01, 2025 - Facilities and Clinicians Treating
Patients With End-stage Kidney Disease and Use
of Home Dialysis: A Randomized … Clinical Trial. … clinical trial or randomized controlled trial).pt. or (control or controls or
controlled or random* … or Comparative Study/ or Controlled Before-
After Studies/ or Cross-Sectional Studies/ or exp Evaluation … , Randomized Controlled Trial (19)
S9 TI S3 AND S6 Limiters - Published Date: 20180301-20230731; English
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-function_research-protocol.pdf
June 13, 2013 - Long-term outcomes
– All-cause mortality
– ≥1 year MACE rates
Type of
study
• We will include randomized … controlled trials and
observational studies with a comparison group … the following databases for primary studies: MEDLINE®, EMBASE®,
and the Cochrane Central Register of Controlled … anticipate the studies to be predominantly observational
in nature, including post-hoc analyses of randomized … controlled trials that studied ACS
interventions.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/engaging-caregivers-appendix-b.xlsx
May 29, 2025 - Mean, Unless Specified) Patient Female % Caregiver Female % Race/Ethnicity
(As Reported by Authors) N Randomized … training and time; framework development time; materials; registry for data collection and feedback Controlled … intensive care unit; LOS = length of stay; NR = not reported; PHQ-9 = Patient Health Questionnaire 9; RCT = randomized … controlled trial; RR = relative risk; SD = standard deviation; SMART = Substance Misuse in Adolescents
-
effectivehealthcare.ahrq.gov/sites/default/files/01_-arthritis_potential_high_impact_june_2012.pdf
January 01, 2012 - The evidence base for PRP lacks large,
blinded, prospective, randomized, controlled trials. … One open-label extension trial demonstrated durable
responses to tofacitinib up to 36 months. … However, some of the experts stated that large,
randomized, double-blind trials are needed to better … perspectives stated that PRP injections could gain
larger acceptance if shown to be effective in randomized … In another clinical trial, patients in whom RA was diagnosed (n=1,070) were given tofacitinib 5 or
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/long-term-care-adults-future_research.pdf
July 01, 2013 - controlled trials (RCTs) were identified. … controlled trial
References
1. … controlled trials (RCTs) were identified. … For example, factors that affect the feasibility of
conducting randomized controlled trials include … controlled trial
20
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-bias_methods.pdf
July 01, 2012 - Categorizing individual studies into general quality classes*
Category Application to Randomized … Controlled Trials
Application to Medical Test
Performance Studies
Low.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_executive.pdf
February 01, 2012 - For example,
the literature on the use of HSCT in
hematologic malignancies is robust,
including randomized … controlled trials
that date back 20 years, and its practice is
supported by evidence-based guidelines … Sources and Study Selection
Electronic databases searched were MEDLINE®,
Embase®, and the Cochrane Controlled … Randomized controlled trials were
rare for any of the indications included in this systematic
review … For inherited metabolic diseases, controlled trials with
sufficient followup are needed to evaluate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-disposition-comments-analgesics-prehospital-setting.pdf
September 03, 2019 - study for opioids or ketamine in to
the review, assuming the pain had to be at least
moderate for a trial … controlled trial. … In EMS, accountability for
controlled substances has a particular set of
challenges, as does deploying … Example: Prehospital
Analgesia with Intranasal Ketamine (PAIN-K): A
Randomized Double-Blind Trial in … The inclusion of mainly
randomized controlled trials is rigorous.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/women-hiv_research-protocol.pdf
March 01, 2016 - design that allows, even under strong assumptions, estimation of the impact
of a resource, including randomized … trials, non-randomized comparisons of cohorts, and
before-after studies. … Any comparative design is
eligible including randomized trials, nonrandomized comparisons of cohorts … the effectiveness and safety of treatments for co-occurring diseases or risk
factors, eligible are randomized
-
effectivehealthcare.ahrq.gov/sites/default/files/s66.pdf
October 01, 2007 - DISCUSSION
Randomized clinical trials have consistently shown the
efficacy of biologic DMARDs in controlling … A controlled clinical trial. Arthritis Rheum. 1985;28:721–730.
5. … A 48-week double-blind, prospective, placebo-
controlled study. … Anti-Tumor Ne-
crosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy
Study Group. … Why randomized controlled clinical trials do not
depict accurately long-term outcomes in rheumatoid arthritis
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-267-adhd-disposition-comments.pdf
March 25, 2024 - Double-Blind Placebo-Controlled Randomized
Clinical Trial of Neurofeedback for Attention-
Deficit/Hyperactivity … Neurofeedback for ADHD: 25-month
follow-up of double-blind randomized controlled trial
(2023). … EEG
neurofeedback for ADHD: double-blind sham-controlled
randomized pilot feasibility trial. … Double-blind placebo-controlled
randomized clinical trial of neurofeedback for attention-
deficit/hyperactivity … A randomized placebo-
controlled trial of electroencephalographic (EEG)
neurofeedback in children with
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fetal-surgery_disposition-comments.pdf
July 05, 2011 - In fact, the poorly conducted randomized
clinical trial in the United States (100% prematurity,
100% … text to be more specific: 8 of 32
(25%) with recurrent pulmonary
infections; and 25% with asthma
controlled … has been put
forth by theData Monitoring and Safety Committee of
the BostonChildren‟s study, a well-controlled … We have strengthened information
regarding the lack of randomized trials
making direct comparisons … The Senat (Eurofoetus) trial randomized patients to
either amnioreduction or laser PRIOR to any
intervention
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-236-maternal-fetal-child-outcomes-disposition-comments.pdf
April 15, 2021 - Rather than using the vague term “trials”, it
would be better to specify if this refers to randomized … controlled trials or other types of trials (e.g., non-
randomized, non-controlled trials). … “Rates of loss of consciousness did not
appear to vary by dose and were similar
among women randomized … specific about the reasons that the evidence
on harms of treatment is of low quality (e.g., poorly
controlled … This now reads: “for both
drugs, we found evidence bases with two
or more randomized controlled trials