Results

Total Results: 1,519 records

Showing results for "randomized controlled trial".

1121. EHC Technical Brief 32: Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-32-pharm-non-pharm-ptsd.pdf
      May 14, 2019 - Treatments for Posttraumatic Stress Disorder: Groundwork for a Publicly Available Repository of Randomized … Controlled Trial Data Draft review available for public comment from December 21, 2018 to January … Nonpharmacologic Treatments for Posttraumatic Stress Disorder: Groundwork for a Publicly Available Repository of Randomized … Controlled Trial Data. … Once the subjects are randomized, they are typically not excluded from later analyses.

1122. App-E-Surv-Report-3-Acute-Pain (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-report-3-acute-pain.xlsx
      May 29, 2025 - Intervention Types Compared Intervention Names and Doses Intervention Dose in Daily Morphine Equivalent N Randomized … Condition Intervention Types Compared Intervention Names and Doses Dose in Daily Morphine Equivalent N Randomized … B Medication controlled pain: 78% (59/76) vs. 69% (51/74), RR 1.13 (95% CI 0.93 to 1.37) NR NR A vs. … 2021 Postoperative to outpatient Norway Total knee arthroplasty Opioid vs. mixed agent A: Oxycodone controlled … acetaminophen 325 mg, single dose B: Ketorolac 10 mg, single dose C: Acetaminophen 500 mg, single dose (Trial

1123. App-E-Surv-Report-2-Acute-Pain (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-report-2-acute-pain.xlsx
      May 29, 2025 - Intervention Types Compared Intervention Names and Doses Intervention Dose in Daily Morphine Equivalent N Randomized … Condition Intervention Types Compared Intervention Names and Doses Dose in Daily Morphine Equivalent N Randomized … B Medication controlled pain: 78% (59/76) vs. 69% (51/74), RR 1.13 (95% CI 0.93 to 1.37) NR NR A vs. … 2021 Postoperative to outpatient Norway Total knee arthroplasty Opioid vs. mixed agent A: Oxycodone controlled … acetaminophen 325 mg, single dose B: Ketorolac 10 mg, single dose C: Acetaminophen 500 mg, single dose (Trial

1124. Radiotherapy Treatments for Head and Neck Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_clinician.pdf
      August 01, 2015 - . �� Well-designed, multicenter, prospective observational studies—where randomized trials are not

1125. Undescended-Testicle Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
      December 01, 2012 - For randomized controlled trials (RCTs), we used the Cochrane Risk of Bias tool;6 for cohort studies … Short-term testicular descent in two-arm, randomized, placebo-controlled studies Study N Length of … controlled trial 11 body of epidemiologic data and data from noncomparative studies to which we … In order for this comparison to be valid, the trial would also need to control for location within … Such a trial would be ethical, as primary orchiopexy would not be the focus of the study and would

1126. Disposition of Comments: Management of Suicidal Thoughts and Behaviors in Youth (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-youth-disposition-comments.pdf
      April 10, 2025 - Novel trial methods with smaller sample sizes could be another suggestion to include here. … We also added some discussion of novel trial methods that could be used including sequential, multiple … assignment randomized trial (SMART) designs and Multiphase Optimization Strategy (MOST) analyses … controlled trials do not find a difference between groups. … trial (SMART) designs (see Collins et al., 2024 for an overview of SMART / intervention optimization

1127. Disposition of Comments Report for CER 134 Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_disposition-comments.pdf
      May 13, 2014 - For disulfiram, we have added the following to the abstract: “Evidence from well-controlled trials does … We did not make any recommendations about trial design. … The part of our report that this comment is referring to was specifically about placebo-controlled trials … Twenty one years later with over 40 randomized trials conducted in four continents by dozens of researchers … Only in one trial did I see the effect disappear and that was in the multi-site Vivitrol trial.

1128. Multidisciplinary Postacute Rehabilitation for Moderate to Severe Traumatic Brain Injury in Adults Disposition of Comments (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation_disposition-comments.pdf
      October 07, 2012 - However, there is little attention to subjects’ level of function at the time of enrollment in the trial … controlled trials. … Rehabilitation consists of multiple component interventions that are difficult to study in a randomized … controlled trial (RCT) approach, while also being highly challenging for patients or therapists to … APTA emphasizes that any identified shortage in randomized controlled trials or perceived lack in quality

1129. Executive summary_Evaluation of Dietary Protein and Amino Acid Requirements: A Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-executive-summary.pdf
      November 01, 2024 - We included randomized and nonrandomized controlled trials, prospective cohort, and nested case-control

1130. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1406.pdf
      February 01, 2015 - Results The table below lists the one topic for which (1) preliminary late-phase clinical trial data … The largest clinical trial to date is scheduled to conclude in 2015. … regardless of ApoE-ε4 status.17 In 2013, the Alzheimer’s Disease Cooperative Study registered the largest randomized … , controlled trial (n=240) to date for this intervention to investigate intranasal insulin’s efficacy … The latter group is lead sponsor on the largest ongoing trial, a phase II/III trial investigating intranasal

1131. Microsoft Word - 3-DKE274__ACEI-ARB-DRI__Comments_Disposition_Table-21_Jan_2011 cyk _2_.docx (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_disposition-comments.pdf
      October 07, 2011 - The question is whether by excluding whatever trial had the original clue, we missed the clue; and … Source: www.effectivehealthcare.ahrq.gov Published Online: October 7, 2011 10 this trial may be … NEJM. 2008. 358;15:1547-1559. [2] The VALUE Trial Group. … and Mortality in the Losartan Intervention For Endpoint Reduction in Hypertension Study (LIFE): A Randomized … Trial Against Atenelol.

1132. Braddock (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/braddock.pdf
      January 01, 2011 - Fewer people remaining  undecided o Fewer patients choosing  major surgery, PSA tests Slide 9: A randomized … trial of telephone care-­‐management strategy • RCT of usual care versus telephone coaches for >170,000

1133. Nonpharmacologic Treatment for Maternal Mental Health Conditions (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-health-pregnant-protocol.pdf
      August 24, 2023 - Our searches will include specific controlled vocabulary terms (MeSH or Emtree), along with specific … Patients' depression treatment preferences and initiation, adherence, and outcome: a randomized primary … The use of paroxetine and cognitive-behavioral therapy in postpartum depression and anxiety: a randomized … controlled trial. … controlled trial SEADS Supplemental Evidence and Data for Systematic review SoE Strength of Evidence

1134. Nonopioid Pharmacologic Treatments for Chronic Pain: Evidence Summary (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-summary.pdf
      April 01, 2020 - Pain: Evidence Summary Purpose of Review Evaluate the benefits and harms of nonopioid drugs in randomized … controlled trials of patients with spe- cific types of chronic pain, considering the effects on pain … The purpose of this review is to evaluate the benefits and harms of nonopioid drugs in randomized controlled … Evidence on intermediate- and long-term outcomes was limited to one trial each, with improvements in … controlled trials.

1135. Disposition of Comments_Comparative Effectiveness Review No. 263: Management of Postpartum Hypertensive Disorders of Pregnancy (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertensive-disorders-pregnancy-disposition-comments.pdf
      May 31, 2023 - For example, one randomized controlled trial of a text-message-based blood pressure surveillance program … Of the 103 women in each arm of the trial, no women in the treatment arm required hospital readmission … Munnery M, Wallace S, Rowe C, Cockcroft JR, Wilkinson IB, on Behalf of the Anglo-Cardiff Collaborative Trial … The Anglo-Cardiff Collaborative Trial II. Hypertension. 2008;51:1476-1482. … In Section 4.6 Implications for Research, we have edited to recommend that trial design and analysis

1136. Strategies for Patient, Family and Caregiver Engagement: Technical Brief Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-family-engagement-protocol.pdf
      December 31, 2019 - standards set by the Institute of Medicine38) published since 2015, including systematic reviews of randomized … controlled trials (RCTs) and/or observational studies with comparison groups. … trial. … Managing depression as a chronic disease: a randomised trial of ongoing treatment in primary care. … A randomized trial to improve patient-centered care and hypertension control in underserved primary

1137. Disposition of Comments for Use of Natriuretic Peptide Measurement in the Management of Heart Failure (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_disposition-comments.pdf
      November 20, 2013 - We have changed the text as noted: “Two articles were randomized controlled trials (RCTs) of BNP-guided … Response General disc Page 444 – it is not clear how prognostic studies would be employed in randomised controlled … However, prognostic models obtained from randomized trial data may have restricted Generalizability … because of strict eligibility criteria for the trial, low recruitment levels, or large numbers refusing … decided to harmonize their assays at a value of 100 ng/ml after the initial BNP Breathing not Properly trial

1138. Disposition of Comments CER 194 Intermittent Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists for Asthma (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-194-disposition-comments-inhaled-corticosteroids.pdf
      March 19, 2018 - Although the duration of a trial is not specifically considered as a domain, the duration could contribute … Reporting bias was also evaluated when a trial was matched with a published protocol on clincitaltrials.gov … race and ethnicity as well as environmental factors all of which contribute to control or poorly controlled … methodological similarity criterion is broadly met through the availability of data from good quality randomized … controlled studies of the treatments of interest.

1139. Asthma-Immunotherapy-2010 Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-immunotherapy-2010_executive.pdf
      January 01, 2010 - Data Sources and Selection We reviewed titles and then abstracts to identify randomized controlled … The magnitude of effect in a trial was considered “weak” if there was less than a 15 percent difference … Literature search RCT = randomized controlled trial; SCIT = subcutaneous immunotherapy; SIT = specific … How to design and evaluate randomized controlled trials in immunotherapy for allergic rhinitis: an … controlled trial SIT Allergen-specific immunotherapy SCIT Subcutaneous immunotherapy SLIT Sublingual

1140. Ch 6-User-Guide-To-Ocer 130129 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/ch_6-user-guide-to-ocer_130129.pdf
      October 30, 2012 - Contextual considerations include the specific disease of interest, target population, clinical trial … An example would be the use of measures of serum lipids as endpoints in randomized trials of the effectiveness … HRQoL is an outcome increasingly used in randomized and non-randomized studies of health interventions … This situation is even greater for products that are subject to controlled distribution or Risk Evaluation … Consider clozapine, an anti-schizophrenia drug that is subject to controlled distribution through a