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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-report-2-acute-pain.xlsx
May 29, 2025 - Intervention Types Compared Intervention Names and Doses Intervention Dose in Daily Morphine Equivalent N Randomized … Condition Intervention Types Compared Intervention Names and Doses Dose in Daily Morphine Equivalent N Randomized … B
Medication controlled pain: 78% (59/76) vs. 69% (51/74), RR 1.13 (95% CI 0.93 to 1.37)
NR NR A vs. … 2021 Postoperative to outpatient Norway Total knee arthroplasty Opioid vs. mixed agent A: Oxycodone controlled … acetaminophen 325 mg, single dose
B: Ketorolac 10 mg, single dose
C: Acetaminophen 500 mg, single dose
(Trial
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effectivehealthcare.ahrq.gov/sites/default/files/comparator-selection-in-observational-chapter-5.pptx
January 01, 2013 - meaningful and methodologically valid
Could still result in confounding by severity if not adequately controlled … comparison groups are associated with the outcome of interest and cannot be adequately adjusted and controlled … rates or outcome definitions, over time could introduce bias in the analyses and must be adequately controlled … Increasing levels of restriction in pharmacoepidemiologic database studies of elderly and comparison with randomized … trial results.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-imaging_clinician.pdf
April 01, 2016 - Since the study was not randomized or
double-blinded, there was also potential for confounding by study … of the cauda equina syn-
drome, or severe or progressive neurologic deficits.
»» Imaging after a trial
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-youth-disposition-comments.pdf
April 10, 2025 - Novel trial
methods with smaller sample sizes could be another
suggestion to include here. … We also added some
discussion of novel trial
methods that could be
used including
sequential, multiple … assignment randomized
trial (SMART) designs
and Multiphase
Optimization Strategy
(MOST) analyses … controlled trials do not find a difference between groups. … trial (SMART) designs (see Collins et al., 2024 for
an overview of SMART / intervention optimization
-
effectivehealthcare.ahrq.gov/sites/default/files/devdelays_adhd_autism_hi_impact.pdf
January 01, 2012 - , double-
blind, placebo-controlled trial that compared HBOT delivering 24% oxygen at 1.3 atmospheric … , double-blind
controlled trial on the efficacy of HBOT for autism. … Randomized trial of hyperbaric oxygen therapy
for children with autism. … Hyperbaric treatment for children with autism:
a multicenter, randomized, double-blind,
controlled … trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/deliberative-methods-demonstration-executive-131125.pdf
November 01, 2013 - This report describes the results of the Deliberative Methods Demonstration, a randomized
controlled … trial comparing deliberative methods with one another and with a control intervention. … controlled trial to
examine the effectiveness of public deliberation and to compare alternative approaches … Effectiveness of Public Deliberation
The randomized design of the Deliberative Methods Demonstration … (This result controlled for differences in other
demographics, including income and education.)
-
effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-32-pharm-non-pharm-ptsd.pdf
May 14, 2019 - Treatments for
Posttraumatic Stress Disorder: Groundwork for a Publicly Available Repository of
Randomized … Controlled Trial Data
Draft review available for public comment from December 21, 2018 to January … Nonpharmacologic
Treatments for Posttraumatic Stress Disorder: Groundwork for a Publicly Available
Repository of Randomized … Controlled Trial Data. … Once the
subjects are randomized, they are typically not excluded from
later analyses.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_clinician.pdf
August 01, 2015 - .
�� Well-designed, multicenter, prospective observational
studies—where randomized trials are not
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1406.pdf
February 01, 2015 - Results
The table below lists the one topic for which (1) preliminary late-phase clinical trial data … The largest
clinical trial to date is scheduled to conclude in 2015. … regardless of ApoE-ε4 status.17
In 2013, the Alzheimer’s Disease Cooperative Study registered the largest randomized … ,
controlled trial (n=240) to date for this intervention to investigate intranasal insulin’s efficacy … The latter group is lead sponsor on the largest ongoing trial, a phase II/III trial investigating
intranasal
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation_disposition-comments.pdf
October 07, 2012 - However, there is little attention
to subjects’ level of function at the time of enrollment in the trial … controlled trials. … Rehabilitation consists of multiple component interventions that are difficult to study in
a randomized … controlled trial (RCT) approach, while also being highly challenging for
patients or therapists to … APTA emphasizes that any identified shortage in randomized
controlled trials or perceived lack in quality
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-executive-summary.pdf
November 01, 2024 - We included randomized and nonrandomized controlled trials,
prospective cohort, and nested case-control
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_disposition-comments.pdf
October 07, 2011 - The question is
whether by excluding whatever trial had the original clue, we missed
the clue; and … Source: www.effectivehealthcare.ahrq.gov
Published Online: October 7, 2011
10
this trial may be … NEJM. 2008.
358;15:1547-1559. [2] The VALUE Trial Group. … and Mortality in the Losartan
Intervention For Endpoint Reduction in Hypertension Study (LIFE): A
Randomized … Trial Against Atenelol.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/engaging-caregivers-appendix-b.xlsx
May 29, 2025 - Mean, Unless Specified) Patient Female % Caregiver Female % Race/Ethnicity
(As Reported by Authors) N Randomized … training and time; framework development time; materials; registry for data collection and feedback Controlled … intensive care unit; LOS = length of stay; NR = not reported; PHQ-9 = Patient Health Questionnaire 9; RCT = randomized … controlled trial; RR = relative risk; SD = standard deviation; SMART = Substance Misuse in Adolescents
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1412.pdf
February 01, 2015 - The largest clinical trial to date is scheduled to conclude in 2015. … In 2013, the Alzheimer’s Disease Cooperative Study registered the largest randomized,
controlled trial … and neuroanatomy, is scheduled to conclude in
February 2015.12 A large German clinical trial (n=90 … The latter cooperative sponsors the largest ongoing trial, a phase II/III trial
investigating intranasal … Available:
https://www.clinicaltrialsregister.eu/ctr-
search/trial/2008-008555-41/DE/.
22.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_disposition-comments.pdf
November 20, 2013 - We have changed the text as noted:
“Two articles were randomized controlled trials (RCTs) of
BNP-guided … Response
General disc Page 444 – it is not clear how prognostic studies would be
employed in randomised controlled … However, prognostic models obtained from randomized
trial data may have restricted Generalizability … because of
strict eligibility criteria for the trial, low recruitment levels,
or large numbers refusing … decided to
harmonize their assays at a value of 100 ng/ml after the
initial BNP Breathing not Properly trial
-
effectivehealthcare.ahrq.gov/sites/default/files/braddock.pdf
January 01, 2011 - Fewer people remaining
undecided
o Fewer patients choosing
major surgery, PSA tests
Slide 9: A randomized … trial of telephone care-‐management strategy
• RCT of usual care versus telephone coaches for >170,000
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-disparities_research-protocol.pdf
July 01, 2015 - Systematic Reviews; Humans; English; Adult: 19+ years 28
#19 Search (#11 AND #12) Filters: Clinical Trial … ; Randomized Controlled Trial; Humans;
English; Adult: 19+ years
375
We will retrieve and review … Inclusion Exclusion
Study design GQs 1, 2, and 4
§ No limitations
GQ 3
§ Systematic reviews
§ Randomized … controlled trials
§ Nonrandomized controlled trials
§ Prospective and retrospective cohort studies
-
effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-summary.pdf
April 01, 2020 - Pain: Evidence Summary
Purpose of Review
Evaluate the benefits and harms of nonopioid drugs
in randomized … controlled trials of patients with spe-
cific types of chronic pain, considering the effects on
pain … The purpose of this review is to evaluate the
benefits and harms of nonopioid drugs in
randomized controlled … Evidence on
intermediate- and long-term outcomes was limited
to one trial each, with improvements in … controlled trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_6-user-guide-to-ocer_130129.pdf
October 30, 2012 - Contextual considerations
include the specific disease of interest, target
population, clinical trial … An example would be the
use of measures of serum lipids as endpoints in
randomized trials of the effectiveness … HRQoL is an outcome increasingly used in
randomized and non-randomized studies of
health interventions … This situation is even greater for products that
are subject to controlled distribution or Risk
Evaluation … Consider clozapine, an anti-schizophrenia drug
that is subject to controlled distribution through
a
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-health-pregnant-protocol.pdf
August 24, 2023 - Our searches will include specific controlled vocabulary terms (MeSH or Emtree), along with specific … Patients' depression treatment preferences and initiation,
adherence, and outcome: a randomized primary … The use of paroxetine and cognitive-behavioral therapy in
postpartum depression and anxiety: a randomized … controlled trial. … controlled trial
SEADS Supplemental Evidence and Data for Systematic review
SoE Strength of Evidence