Results

Total Results: 1,524 records

Showing results for "randomized controlled trial".

1121. #05 DEPRESSION (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_june_2012.pdf
      January 01, 2012 - trial design and outcomes seen thus far. … In the double- blind, sham-controlled phase (n=14), the mean (SD) Y-BOCS score difference between active … Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled … add-on trial. … Controlled substance schedules. [internet].

1122. Slide 1
      effectivehealthcare.ahrq.gov/sites/default/files/comparator-selection-in-observational-chapter-5.pptx
      January 01, 2013 - meaningful and methodologically valid Could still result in confounding by severity if not adequately controlled … comparison groups are associated with the outcome of interest and cannot be adequately adjusted and controlled … rates or outcome definitions, over time could introduce bias in the analyses and must be adequately controlled … Increasing levels of restriction in pharmacoepidemiologic database studies of elderly and comparison with randomized … trial results.

1123. PULMONARY with "Discussions" in Exec Summary (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1312.pdf
      December 01, 2013 - This program’s high-impact potential will be reevaluated after results of the IHI-funded trial are … Results of a randomized controlled trial (RCT) on prophylactic azithromycin for COPD exacerbations … III trial.5,6 In a randomized, double-blind, placebo-controlled, phase III trial, cosponsored by the … : In a randomized controlled trial (RTC), patients with COPD who were at increased risk of exacerbations … One trial investigated the OCS Lung’s feasibility for lung preservation during lung transplantation

1124. Disposition of Comments Report for Oral Contraceptive Use for the Primary Prevention of Ovarian Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_disposition-comments.pdf
      June 07, 2013 - trial. … This population would be more willing to participate as well, and more motivated to adhere to the trial … If all epidemiological evidence is to be regarded as at best moderate without a randomized trial then … controlled trials. … controlled trials

1125. Disposition of Comments_Comparative Effectiveness Review No. 263: Management of Postpartum Hypertensive Disorders of Pregnancy (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertensive-disorders-pregnancy-disposition-comments.pdf
      May 31, 2023 - For example, one randomized controlled trial of a text-message-based blood pressure surveillance program … Of the 103 women in each arm of the trial, no women in the treatment arm required hospital readmission … Munnery M, Wallace S, Rowe C, Cockcroft JR, Wilkinson IB, on Behalf of the Anglo-Cardiff Collaborative Trial … The Anglo-Cardiff Collaborative Trial II. Hypertension. 2008;51:1476-1482. … In Section 4.6 Implications for Research, we have edited to recommend that trial design and analysis

1126. Disposition of Comments CER 194 Intermittent Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists for Asthma (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-194-disposition-comments-inhaled-corticosteroids.pdf
      March 19, 2018 - Although the duration of a trial is not specifically considered as a domain, the duration could contribute … Reporting bias was also evaluated when a trial was matched with a published protocol on clincitaltrials.gov … race and ethnicity as well as environmental factors all of which contribute to control or poorly controlled … methodological similarity criterion is broadly met through the availability of data from good quality randomized … controlled studies of the treatments of interest.

1127. CER 210: Disposition of Comments for Breastfeeding Programs and Policies, Breastfeeding Uptake, and Maternal Health Outcomes in Developed Countries (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-210-breastfeeding-disposition-comments.pdf
      January 01, 2020 - , a cluster- randomized controlled trial." … , a cluster-randomized controlled trial." … , a cluster- randomized controlled trial." … The Cohen article is not a controlled trial, but there is nothing in the methods section that states … Peer Reviewer 6 General Comments The WIC food package study was clearly not a controlled trial but

1128. EHC Technical Brief 32: Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-32-pharm-non-pharm-ptsd.pdf
      May 14, 2019 - Treatments for Posttraumatic Stress Disorder: Groundwork for a Publicly Available Repository of Randomized … Controlled Trial Data Draft review available for public comment from December 21, 2018 to January … Nonpharmacologic Treatments for Posttraumatic Stress Disorder: Groundwork for a Publicly Available Repository of Randomized … Controlled Trial Data. … Once the subjects are randomized, they are typically not excluded from later analyses.

1129. Disposition of Comments: Management of Suicidal Thoughts and Behaviors in Youth (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-youth-disposition-comments.pdf
      April 10, 2025 - Novel trial methods with smaller sample sizes could be another suggestion to include here. … We also added some discussion of novel trial methods that could be used including sequential, multiple … assignment randomized trial (SMART) designs and Multiphase Optimization Strategy (MOST) analyses … controlled trials do not find a difference between groups. … trial (SMART) designs (see Collins et al., 2024 for an overview of SMART / intervention optimization

1130. advanced-care-decision-aids-protocol-131209 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/advanced-care-decision-aids_research-protocol.pdf
      December 09, 2013 - We will include studies published in English of any sample size and any design (randomized controlled … trial, controlled clinical trial, uncontrolled observational trial, and case reports and series).

1131. Disposition of comments_Comparative Effectiveness Review No. 244: Safety of Vaccines Used for Routine Immunization in the United States: An Update (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/cer-244-safety-of-vaccines.pdf
      May 25, 2021 - - controlled designs). … Evidence [Comment in pdf file on “The most frequent study designs identified in the update were randomized … followed by cohort studies (n=26), pre-post designs (n=12), case-control designs (n=9), and one non-randomized … controlled clinical trial, along with 13 others that used selfcontrol methods (either self- controlled … The data for autism comes from the clinical trial record for NCT01240746; this trial is the basis of

1132. App-E-Surv-Report-3-Acute-Pain (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-report-3-acute-pain.xlsx
      October 08, 2025 - Intervention Types Compared Intervention Names and Doses Intervention Dose in Daily Morphine Equivalent N Randomized … Condition Intervention Types Compared Intervention Names and Doses Dose in Daily Morphine Equivalent N Randomized … B Medication controlled pain: 78% (59/76) vs. 69% (51/74), RR 1.13 (95% CI 0.93 to 1.37) NR NR A vs. … 2021 Postoperative to outpatient Norway Total knee arthroplasty Opioid vs. mixed agent A: Oxycodone controlled … acetaminophen 325 mg, single dose B: Ketorolac 10 mg, single dose C: Acetaminophen 500 mg, single dose (Trial

1133. App-E-Surv-Report-2-Acute-Pain (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-report-2-acute-pain.xlsx
      October 08, 2025 - Intervention Types Compared Intervention Names and Doses Intervention Dose in Daily Morphine Equivalent N Randomized … Condition Intervention Types Compared Intervention Names and Doses Dose in Daily Morphine Equivalent N Randomized … B Medication controlled pain: 78% (59/76) vs. 69% (51/74), RR 1.13 (95% CI 0.93 to 1.37) NR NR A vs. … 2021 Postoperative to outpatient Norway Total knee arthroplasty Opioid vs. mixed agent A: Oxycodone controlled … acetaminophen 325 mg, single dose B: Ketorolac 10 mg, single dose C: Acetaminophen 500 mg, single dose (Trial

1134. AHRQ Slide Template-Widescreen
      effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-child-adolesc-mental-health-grand-rounds.pptx
      May 22, 2025 - treatment study of >4 weeks Any study of evaluating a monitoring strategy Diagnostic accuracy study Controlled … We also identified 69 trial registrations through clinical trial registries. … Of the 65 included studies, 33 studies were randomized clinical trials (RCTs), 13 were comparative After … FFT Designed for bipolar youths. 1 trial found no differences for SI. … emerging biological treatments on suicide highlight a gap in the evidence base and a critical need for controlled

1135. #06 Developmental Delays ADHD, and Autism (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/devdelays_adhd_autism_hi_impact.pdf
      January 01, 2012 - , double- blind, placebo-controlled trial that compared HBOT delivering 24% oxygen at 1.3 atmospheric … , double-blind controlled trial on the efficacy of HBOT for autism. … Randomized trial of hyperbaric oxygen therapy for children with autism. … Hyperbaric treatment for children with autism: a multicenter, randomized, double-blind, controlled … trial.

1136. Evidence Report on the (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_research-protocol.pdf
      December 06, 2010 - evidence (study design and other criteria) Original research; eligible study designs include: • Randomized … controlled trials with a sample size ≥100 • Nonrandomized controlled trials • Observational studies

1137. Nonopioid Pharmacologic Treatments for Chronic Pain: Evidence Summary (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-summary.pdf
      April 01, 2020 - Pain: Evidence Summary Purpose of Review Evaluate the benefits and harms of nonopioid drugs in randomized … controlled trials of patients with spe- cific types of chronic pain, considering the effects on pain … The purpose of this review is to evaluate the benefits and harms of nonopioid drugs in randomized controlled … Evidence on intermediate- and long-term outcomes was limited to one trial each, with improvements in … controlled trials.

1138. Diabetes Mellitus (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_2012-12-10.pdf
      January 01, 2012 - to be completed in September 2011, but the National Clinical Trials database listed the trial as … Extended-release exenatide is a controlled-release, once-weekly formulation delivered by subcutaneous … Another research expert noted that another clinical trial compared this intervention to behavior and … In October 2012, the manufacturer stated plans to commence a phase III trial in January 2013, having … completed analysis of phase II trial results to determine an optimal dosing regimen for the planned

1139. Multidisciplinary Postacute Rehabilitation for Moderate to Severe Traumatic Brain Injury in Adults Disposition of Comments (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation_disposition-comments.pdf
      October 07, 2012 - However, there is little attention to subjects’ level of function at the time of enrollment in the trial … controlled trials. … Rehabilitation consists of multiple component interventions that are difficult to study in a randomized … controlled trial (RCT) approach, while also being highly challenging for patients or therapists to … APTA emphasizes that any identified shortage in randomized controlled trials or perceived lack in quality

1140. Ch 6-User-Guide-To-Ocer 130129 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/ch_6-user-guide-to-ocer_130129.pdf
      October 30, 2012 - Contextual considerations include the specific disease of interest, target population, clinical trial … An example would be the use of measures of serum lipids as endpoints in randomized trials of the effectiveness … HRQoL is an outcome increasingly used in randomized and non-randomized studies of health interventions … This situation is even greater for products that are subject to controlled distribution or Risk Evaluation … Consider clozapine, an anti-schizophrenia drug that is subject to controlled distribution through a