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Total Results: 1,523 records

Showing results for "randomized controlled trial".

  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-report-2-acute-pain.xlsx
    May 29, 2025 - Intervention Types Compared Intervention Names and Doses Intervention Dose in Daily Morphine Equivalent N Randomized … Condition Intervention Types Compared Intervention Names and Doses Dose in Daily Morphine Equivalent N Randomized … B Medication controlled pain: 78% (59/76) vs. 69% (51/74), RR 1.13 (95% CI 0.93 to 1.37) NR NR A vs. … 2021 Postoperative to outpatient Norway Total knee arthroplasty Opioid vs. mixed agent A: Oxycodone controlled … acetaminophen 325 mg, single dose B: Ketorolac 10 mg, single dose C: Acetaminophen 500 mg, single dose (Trial
  2. effectivehealthcare.ahrq.gov/sites/default/files/comparator-selection-in-observational-chapter-5.pptx
    January 01, 2013 - meaningful and methodologically valid Could still result in confounding by severity if not adequately controlled … comparison groups are associated with the outcome of interest and cannot be adequately adjusted and controlled … rates or outcome definitions, over time could introduce bias in the analyses and must be adequately controlled … Increasing levels of restriction in pharmacoepidemiologic database studies of elderly and comparison with randomizedtrial results.
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-imaging_clinician.pdf
    April 01, 2016 - Since the study was not randomized or double-blinded, there was also potential for confounding by study … of the cauda equina syn- drome, or severe or progressive neurologic deficits. »» Imaging after a trial
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-youth-disposition-comments.pdf
    April 10, 2025 - Novel trial methods with smaller sample sizes could be another suggestion to include here. … We also added some discussion of novel trial methods that could be used including sequential, multiple … assignment randomized trial (SMART) designs and Multiphase Optimization Strategy (MOST) analyses … controlled trials do not find a difference between groups. … trial (SMART) designs (see Collins et al., 2024 for an overview of SMART / intervention optimization
  5. effectivehealthcare.ahrq.gov/sites/default/files/devdelays_adhd_autism_hi_impact.pdf
    January 01, 2012 - , double- blind, placebo-controlled trial that compared HBOT delivering 24% oxygen at 1.3 atmospheric … , double-blind controlled trial on the efficacy of HBOT for autism. … Randomized trial of hyperbaric oxygen therapy for children with autism. … Hyperbaric treatment for children with autism: a multicenter, randomized, double-blind, controlledtrial.
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/deliberative-methods-demonstration-executive-131125.pdf
    November 01, 2013 - This report describes the results of the Deliberative Methods Demonstration, a randomized controlledtrial comparing deliberative methods with one another and with a control intervention. … controlled trial to examine the effectiveness of public deliberation and to compare alternative approaches … Effectiveness of Public Deliberation The randomized design of the Deliberative Methods Demonstration … (This result controlled for differences in other demographics, including income and education.)
  7. effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-32-pharm-non-pharm-ptsd.pdf
    May 14, 2019 - Treatments for Posttraumatic Stress Disorder: Groundwork for a Publicly Available Repository of RandomizedControlled Trial Data Draft review available for public comment from December 21, 2018 to January … Nonpharmacologic Treatments for Posttraumatic Stress Disorder: Groundwork for a Publicly Available Repository of RandomizedControlled Trial Data. … Once the subjects are randomized, they are typically not excluded from later analyses.
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_clinician.pdf
    August 01, 2015 - . �� Well-designed, multicenter, prospective observational studies—where randomized trials are not
  9. effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1406.pdf
    February 01, 2015 - Results The table below lists the one topic for which (1) preliminary late-phase clinical trial data … The largest clinical trial to date is scheduled to conclude in 2015. … regardless of ApoE-ε4 status.17 In 2013, the Alzheimer’s Disease Cooperative Study registered the largest randomized … , controlled trial (n=240) to date for this intervention to investigate intranasal insulin’s efficacy … The latter group is lead sponsor on the largest ongoing trial, a phase II/III trial investigating intranasal
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation_disposition-comments.pdf
    October 07, 2012 - However, there is little attention to subjects’ level of function at the time of enrollment in the trialcontrolled trials. … Rehabilitation consists of multiple component interventions that are difficult to study in a randomizedcontrolled trial (RCT) approach, while also being highly challenging for patients or therapists to … APTA emphasizes that any identified shortage in randomized controlled trials or perceived lack in quality
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-executive-summary.pdf
    November 01, 2024 - We included randomized and nonrandomized controlled trials, prospective cohort, and nested case-control
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_disposition-comments.pdf
    October 07, 2011 - The question is whether by excluding whatever trial had the original clue, we missed the clue; and … Source: www.effectivehealthcare.ahrq.gov Published Online: October 7, 2011 10 this trial may be … NEJM. 2008. 358;15:1547-1559. [2] The VALUE Trial Group. … and Mortality in the Losartan Intervention For Endpoint Reduction in Hypertension Study (LIFE): A RandomizedTrial Against Atenelol.
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/engaging-caregivers-appendix-b.xlsx
    May 29, 2025 - Mean, Unless Specified) Patient Female % Caregiver Female % Race/Ethnicity (As Reported by Authors) N Randomized … training and time; framework development time; materials; registry for data collection and feedback Controlled … intensive care unit; LOS = length of stay; NR = not reported; PHQ-9 = Patient Health Questionnaire 9; RCT = randomizedcontrolled trial; RR = relative risk; SD = standard deviation; SMART = Substance Misuse in Adolescents
  14. effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1412.pdf
    February 01, 2015 - The largest clinical trial to date is scheduled to conclude in 2015. … In 2013, the Alzheimer’s Disease Cooperative Study registered the largest randomized, controlled trial … and neuroanatomy, is scheduled to conclude in February 2015.12 A large German clinical trial (n=90 … The latter cooperative sponsors the largest ongoing trial, a phase II/III trial investigating intranasal … Available: https://www.clinicaltrialsregister.eu/ctr- search/trial/2008-008555-41/DE/. 22.
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_disposition-comments.pdf
    November 20, 2013 - We have changed the text as noted: “Two articles were randomized controlled trials (RCTs) of BNP-guided … Response General disc Page 444 – it is not clear how prognostic studies would be employed in randomised controlled … However, prognostic models obtained from randomized trial data may have restricted Generalizability … because of strict eligibility criteria for the trial, low recruitment levels, or large numbers refusing … decided to harmonize their assays at a value of 100 ng/ml after the initial BNP Breathing not Properly trial
  16. Braddock (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/braddock.pdf
    January 01, 2011 - Fewer people remaining  undecided o Fewer patients choosing  major surgery, PSA tests Slide 9: A randomizedtrial of telephone care-­‐management strategy • RCT of usual care versus telephone coaches for >170,000
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-disparities_research-protocol.pdf
    July 01, 2015 - Systematic Reviews; Humans; English; Adult: 19+ years 28 #19 Search (#11 AND #12) Filters: Clinical Trial … ; Randomized Controlled Trial; Humans; English; Adult: 19+ years 375 We will retrieve and review … Inclusion Exclusion Study design GQs 1, 2, and 4 § No limitations GQ 3 § Systematic reviews § Randomizedcontrolled trials § Nonrandomized controlled trials § Prospective and retrospective cohort studies
  18. effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-summary.pdf
    April 01, 2020 - Pain: Evidence Summary Purpose of Review Evaluate the benefits and harms of nonopioid drugs in randomizedcontrolled trials of patients with spe- cific types of chronic pain, considering the effects on pain … The purpose of this review is to evaluate the benefits and harms of nonopioid drugs in randomized controlled … Evidence on intermediate- and long-term outcomes was limited to one trial each, with improvements in … controlled trials.
  19. effectivehealthcare.ahrq.gov/sites/default/files/ch_6-user-guide-to-ocer_130129.pdf
    October 30, 2012 - Contextual considerations include the specific disease of interest, target population, clinical trial … An example would be the use of measures of serum lipids as endpoints in randomized trials of the effectiveness … HRQoL is an outcome increasingly used in randomized and non-randomized studies of health interventions … This situation is even greater for products that are subject to controlled distribution or Risk Evaluation … Consider clozapine, an anti-schizophrenia drug that is subject to controlled distribution through a
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-health-pregnant-protocol.pdf
    August 24, 2023 - Our searches will include specific controlled vocabulary terms (MeSH or Emtree), along with specific … Patients' depression treatment preferences and initiation, adherence, and outcome: a randomized primary … The use of paroxetine and cognitive-behavioral therapy in postpartum depression and anxiety: a randomizedcontrolled trial. … controlled trial SEADS Supplemental Evidence and Data for Systematic review SoE Strength of Evidence

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