Results

Total Results: 1,519 records

Showing results for "randomized controlled trial".

1101. Engaging Patients in Information Sharing and Data Collection: The Role of Patient-Powered Registries and Research Networks (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholders-engagement-others_white-paper.pdf
      September 01, 2013 - More importantly, the nature of the clinical trial may or may not yield information that patients and … world” practice and the effectiveness of treatments and procedures, and are to be distinguished from randomized … controlled trials or scientific experiments that cannot measure real-life experience, in some cases … In the view of some, only registries that are created, maintained, and controlled by patients or patient … Terms such as “patient-generated,” “patient-run,” “patient-powered,” and “participant-controlled” can

1102. Appendix K Rapid Evidence Review Treatments for Clostridium difficile Colitis (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/clinical-pathway-methods-report-appendix-k.pdf
      February 01, 2018 - • One small randomized controlled trial for adjunct use of probiotics had some positive results. … The purpose of this rapid review is to identify recent guidelines, systematic reviews, randomized controlled … controlled trial'/de OR 'systematic review'/de) 273 10 7 AND (rct OR random* OR meta* OR systematic … Since this was a small trial (n=33), the authors concluded that probiotic therapy shows promise for … A randomized controlled trial of probiotics for Clostridium difficile infection in adults (PICO).

1103. Research Protocol: Breast Reconstruction After Mastectomy (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-reconstruction-mastectomy-protocol.pdf
      April 09, 2020 - chemotherapy Timing • Any Setting • Any, including single- and multicenter Design • Randomized … trial. … trial. … difference NRCS nonrandomized comparative study OR odds ratio PAP profundal artery perforator RCT randomized … controlled trial ROBINS-I Risk of Bias in Nonrandomized Studies of Interventions SIEA superficial

1104. Pressure-Ulcer-Prevention Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-prevention_executive.pdf
      May 01, 2013 - July 2012, CINAHL (EBSCOhost®) from 1988 through July 2012, and the Cochrane Central Register of Controlled … For Key Questions 1 and 4, we included controlled clinical trials and cohort studies. … For Key Question 3, we included controlled clinical trials. … KQ 4c. 0 trials KQ 1 KQ 2 KQ 3 KQ 4 aCochrane databases include the Cochrane Central Register of Controlled … randomized to repositioning at 2-, 3-, or 4-hour intervals, should provide more rigorous evidence

1105. advanced-care-decision-aids-protocol-131209 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/advanced-care-decision-aids_research-protocol.pdf
      December 09, 2013 - We will include studies published in English of any sample size and any design (randomized controlled … trial, controlled clinical trial, uncontrolled observational trial, and case reports and series).

1106. Research White Paper Managing Missing Data in Patient Registries Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
      February 01, 2018 - accounted for in analyses to the extent possible (known as informative censoring in the context of randomized … Additionally, while randomized clinical trials (RCTs) often limit their samples to a narrow and often

1107. Methods Guide for Medical Test Reviews - Editorial (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guide-editorial_methods.pdf
      July 01, 2012 - detailed handbook for authors of systematic reviews.5 This methods guide focuses primarily on reviews of randomized … controlled trials of interventions. … Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement

1108. #05 DEPRESSION (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_june_2012.pdf
      January 01, 2012 - trial design and outcomes seen thus far. … In the double- blind, sham-controlled phase (n=14), the mean (SD) Y-BOCS score difference between active … Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled … add-on trial. … Controlled substance schedules. [internet].

1109. Methods Guide for Medical Test Reviews Chapter 10 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-decision-models_methods.pdf
      July 01, 2012 - Such evidence could be obtained from well designed, conducted and analyzed randomized trials, or even … Randomized trials may exist suggesting that the treatment effects are similar in patients identified … of the diagnostic performance of PET to identify AD, but does not include longitudinal studies or randomized … Using the principles of randomized controlled trial design to guide test evaluation. … Optimization of CT colonography technique: prospective trial in 180 patients.

1110. Evidence Summary_Comparative Effectiveness Review No. 248: Prehabilitation and Rehabilitation for Major Joint Replacement (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/joint-replacement-evidence%20-summary.pdf
      November 01, 2021 - Our searches targeted randomized controlled trials (RCTs) and adequately adjusted nonrandomized comparative

1111. Amendment_HIE-Protocol_3-14-2015 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/health-information-exchange_research-protocol.pdf
      April 20, 2015 - Randomized controlled clinical trials (RCTs) and systematic reviews of such trials will be included … 2015 9 Literature Databases: Ovid MEDLINE, PsycINFO, CINHAL, EMBASE, Cochrane Central Register of Controlled … hereafter, Methods Guide).26 Included studies will be classified according to type of design (e.g., randomized … trial, nonrandomized trial, observational study, etc.)

1112. Interventions for Breathlessness in Patients With Advanced Cancer: Evidence Summary (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/dyspnea-advanced-cancer-summary-1.pdf
      November 01, 2020 - We found 29 randomized controlled trials (RCTs) (2,423 patients). … the evidence supported the effectiveness of opioids for breathlessness, all but one of the placebo-controlled

1113. Disposition of Comments Report for Oral Contraceptive Use for the Primary Prevention of Ovarian Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_disposition-comments.pdf
      June 07, 2013 - trial. … This population would be more willing to participate as well, and more motivated to adhere to the trial … If all epidemiological evidence is to be regarded as at best moderate without a randomized trial then … controlled trials. … controlled trials

1114. PULMONARY with "Discussions" in Exec Summary (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1312.pdf
      December 01, 2013 - This program’s high-impact potential will be reevaluated after results of the IHI-funded trial are … Results of a randomized controlled trial (RCT) on prophylactic azithromycin for COPD exacerbations … III trial.5,6 In a randomized, double-blind, placebo-controlled, phase III trial, cosponsored by the … : In a randomized controlled trial (RTC), patients with COPD who were at increased risk of exacerbations … One trial investigated the OCS Lung’s feasibility for lung preservation during lung transplantation

1115. Amended Protocol: Management of Infantile Epilepsy (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-epilepsy-amended-protocol.pdf
      March 07, 2021 - We will not require that patients be randomized to groups, nor will we require that studies plan their … For Key Question 3 (harms), we will include single-arm studies as well as controlled studies. 6. … We will search the following databases using controlled vocabulary and text words: EMBASE, MEDLINE, … We will assess randomized trials for Key Question 1 and 2 using the Cochrane Risk of Bias 2 (ROB2) … A cohort study of summary reports of controlled trials. JAMA. 1990 Mar 9;263(10):1401-5.

1116. Back-Pain-Imaging Clinician (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-imaging_clinician.pdf
      April 01, 2016 - Since the study was not randomized or double-blinded, there was also potential for confounding by study … of the cauda equina syn- drome, or severe or progressive neurologic deficits. »» Imaging after a trial

1117. Modeling to evaluate benefits and harms of new diagnostic tests compared to established diagnostic tests – uses and limitations (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/benefits-harms-modeling_research.pdf
      November 19, 2009 - most robust empirical demonstration of the utility of a medical test is through a properly designed randomized … These had not been compared head-to-head in a clinical trial.19 3 Conversely, management strategies … measuring sensitivity and specificity sufficient to evaluate a diagnostic test, and when do we need randomized … comparative evidence of test accuracy and other intermediate outcomes be used as an alternative to randomized … controlled trials?

1118. Slide 1
      effectivehealthcare.ahrq.gov/sites/default/files/comparator-selection-in-observational-chapter-5.pptx
      January 01, 2013 - meaningful and methodologically valid Could still result in confounding by severity if not adequately controlled … comparison groups are associated with the outcome of interest and cannot be adequately adjusted and controlled … rates or outcome definitions, over time could introduce bias in the analyses and must be adequately controlled … Increasing levels of restriction in pharmacoepidemiologic database studies of elderly and comparison with randomized … trial results.

1119. Community Forum Deliberative Methods Demonstration: Evaluating Effectiveness and Eliciting Public Views on Use of Evidence--Executive Summary (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/deliberative-methods-demonstration-executive-131125.pdf
      November 01, 2013 - This report describes the results of the Deliberative Methods Demonstration, a randomized controlled … trial comparing deliberative methods with one another and with a control intervention. … controlled trial to examine the effectiveness of public deliberation and to compare alternative approaches … Effectiveness of Public Deliberation The randomized design of the Deliberative Methods Demonstration … (This result controlled for differences in other demographics, including income and education.)

1120. #06 Developmental Delays ADHD, and Autism (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/devdelays_adhd_autism_hi_impact.pdf
      January 01, 2012 - , double- blind, placebo-controlled trial that compared HBOT delivering 24% oxygen at 1.3 atmospheric … , double-blind controlled trial on the efficacy of HBOT for autism. … Randomized trial of hyperbaric oxygen therapy for children with autism. … Hyperbaric treatment for children with autism: a multicenter, randomized, double-blind, controlled … trial.