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Total Results: 1,524 records

Showing results for "randomized controlled trial".

1081. Organisation (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-radiation_appendixes.pdf
      June 16, 2008 - Final report of a Northern California Oncology Group randomized prospective clinical trial. … A prospective, randomized, dynamically balanced trial. … A randomized controlled trial of varying radiation doses in the treatment of choroidal melanoma. … Advanced prostate cancer: the results of a randomized comparative trial of high dose irradiation boosting … controlled trial [see comment].

1082. Engaging Patients in Information Sharing and Data Collection: The Role of Patient-Powered Registries and Research Networks (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholders-engagement-others_white-paper.pdf
      September 01, 2013 - More importantly, the nature of the clinical trial may or may not yield information that patients and … world” practice and the effectiveness of treatments and procedures, and are to be distinguished from randomized … controlled trials or scientific experiments that cannot measure real-life experience, in some cases … In the view of some, only registries that are created, maintained, and controlled by patients or patient … Terms such as “patient-generated,” “patient-run,” “patient-powered,” and “participant-controlled” can

1083. Comparative Effectiveness and Safety of New Therapies (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-glucose-control_research.pdf
      July 01, 2010 - We have published an observational study regarding the effectiveness of exenatide;16 however, controlled … Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: a randomized … trial. … twice-daily exenatide and biphasic insulin aspart in patients with type 2 diabetes who were suboptimally controlled

1084. Postpartum Care for Women Up to One Year After Pregnancy (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/postpartum-care-one-year-protocol-amendment.pdf
      April 25, 2022 - controlled trials (N ≥10 participants per group) ● Nonrandomized comparative studies, longitudinal … U.S. only ● Outpatient care ● Exclude: Institutionalized settings (e.g., prisons) Design ● Randomized … controlled trials (N ≥10 participants per group) ● Nonrandomized comparative studies, longitudinal … We will include specific controlled vocabulary terms (MeSH or Emtree), along with specific free-text … controlled trial ROBINS-I Risk of Bias in Nonrandomized Studies of Interventions SoE strength of evidence

1085. Disposition of Comments_Systematic Review: Implementing Recommended Mental Health and Substance Use Screening and Counseling Interventions in Primary Care Settings for in Children and Adolescents (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/behavioral-health-screening-disposition-comments.pdf
      April 09, 2025 - This statement refers to the use of the risk of bias assessment tool for randomized controlled trials … (2017) Cognitive-behavioral family treatment for suicide attempt prevention: a randomized controlled … trial. … Controlled Trial. … (2010) Attachment-based family therapy for adolescents with suicidal ideation: A randomized controlled

1086. PEPTIC ULCER #11 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/11_pepticulcer_potential_high_impact_june_2012.pdf
      January 01, 2012 - In the absence of randomized or long-term trials for POEM, some experts are uncertain of POEM’s degree … In three patients, GERD symptoms were controlled with proton pump inhibitors. 24 In another case … In the absence of randomized or long-term trials for POEM, some experts remain unsure how impactful … controlled trials. … , double-blind, placebo-controlled, phase III trial, investigators reported that 63% of patients (n

1087. Layout 1 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypothyroidism-hyperthyroidism-screening-treatment_executive.pdf
      October 01, 2011 - Additional materials were sought by searching for regulatory information, clinical trial registries, … We identified no randomized controlled trials (RCTs) or observational studies comparing the outcomes … We identified no RCTs or controlled observational studies that evaluated harms associated with screening … The largest trial included 120 patients. … Two controlled trials assessed the efficacy of treatment of subclinical hyperthyroidism; both of these

1088. PULMONARY with "Discussions" in Exec Summary (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1506.pdf
      October 01, 2015 - Clinical trials: In the phase III, randomized, double-blind, placebo-controlled TRAFFIC trial, patients … , double-blind, placebo-controlled TRANSPORT trial, patients (n=559) homozygous for the F508del mutation … In the phase III, randomized, double-blind, controlled ASCEND trial, patients (n=555) with IPF were … In two replicate, phase III, randomized, double-blind, 52-week trials (INPULSIS-1 and INPULSIS-2), … In the phase III, randomized, controlled, INSPIRE trial, patients (n=264) who were registered primary

1089. Stem-Cell-Children Surveillance (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_surveillance.pdf
      October 29, 2012 - Indexed Citations and Ovid MEDLINE(R) <1946 to September 25, 2012> and the Cochrane Central Register of Controlled … search strategies appearing in the CER’s Appendix A.1 The syntax and vocabulary, which include both controlled … one new trial), practice guideline (from major specialty organization or published in peer-reviewed … is defined as: 1) a trial published in top 5 general medical journals such as: Lancet, JAMA, Annals … No new evidence NA NA NA NA NA CER=comparative effectiveness review; RCT=randomized controlled trial

1090. autism-update-protocol-130920 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-update_research-protocol.pdf
      September 20, 2013 - method relies heavily on one-on-one therapy sessions during which a trained therapist uses discrete trial … And for randomized controlled trials, was there an intent-to-treat analysis? … controlled trial, prospective observational study, etc.). … we will present results by study design, with a focus on those designs less subject to bias (i.e., randomized … controlled trials, controlled trials) and those studies rated as of higher quality in our quality-assessment

1091. Appendicitis Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_executive.pdf
      December 01, 2015 - Searches were conducted in PubMed®, Embase®, the Cochrane Central Register of Controlled Trials, and … controlled trials (RCTs), one reviewer extracted and a second reviewer verified the data. … Flow chart of included studies CCRCT = Cochrane Central Register of Controlled Trials; KQ = Key Question … Flow chart of included studies CCRCT = Cochrane Central Register of Controlled Trials; KQ = Key Question … If randomized studies are deemed necessary, consideration should be given to paired randomized designs

1092. Disposition of Comments Report for Vitamin D and Calcium: A Systematic Review of Health Outcomes (Update) (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/vitamin-d-calcium_disposition-comments.pdf
      September 15, 2014 - clinical trial were combined. … There appears to be no effort to find those trials, for example, the Lappe trial in Nebraska did not … Both the update and older report cover studies with different designs (randomized clinical trials, prospective … Lynette, Vitamin D does not Increase Calcium Absorption in Young Women: A Randomized Clinical Trial … (Reference: Aloia, J.F., et al., A randomized controlled trial of vitamin D3 supplementation in African

1093. AHRQ Evidence-based Practice Center Program Research Gaps Summary: Telehealth (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/ehc-research-gaps-telehealth.pdf
      April 01, 2023 - However, recognizing potential ethical and logistical challenges, consider different trial designs … Study Design • Nonrandomized controlled study (NRS) designs, ideally using a propensity score matching … Study Design • Randomized controlled trials, with clearly defined comparison groups and health outcomes

1094. Radiotherapy Treatments for Head and Neck Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_clinician.pdf
      August 01, 2015 - . �� Well-designed, multicenter, prospective observational studies—where randomized trials are not

1095. Evidence Summary_Comparative Effectiveness Review No. 248: Prehabilitation and Rehabilitation for Major Joint Replacement (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/joint-replacement-evidence%20-summary.pdf
      November 01, 2021 - Our searches targeted randomized controlled trials (RCTs) and adequately adjusted nonrandomized comparative

1096. #14 SUBSTANCE ABUSE (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/14_substanceabuse_potential_high_impact_june_2012.pdf
      January 01, 2012 - A larger trial is planned. … in the ClinicalTrials.gov database, the developers of the program state that they are conducting a randomized … , controlled trial that will investigate the Text2Quit program combined with the Smokefree.gov program … July 2011 press release, the manufacturer stated that data from a phase III placebo- and active-drug-controlled … Naltrexone (once-monthly controlled-release, Medisorb). [138 p].

1097. Screening and Diagnosing Gestational Diabetes Mellitus Disposition of Comments Report (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/gestational-diabetes-screening-diagnosis_disposition-comments.pdf
      January 01, 2020 - The decision to limit the review to randomized controlled trials and cohort studies is stated but the … For key question 4 the RCTs used are not of equal quality and differ significantly in the population randomized … for GDM.2 We applaud the reviewers for considering the full body of available evidence—including randomized … controlled trials; nonrandomized controlled trials; and prospective and retrospective cohort studies—in … At least two high-quality randomized controlled trials of treatment of lesser degrees of glucose intolerance

1098. EHC Research Protocol: Documentation Burden (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/documentation-burden-protocol.pdf
      July 26, 2023 - In-Process & Other Non-Indexed Citations, MEDLINE® Daily, MEDLINE®, Cochrane Central Registrar of Controlled … language studies • Conference abstracts Abbreviations: EHR = electronic health record; RCT = randomized … Language Processing PICOTS Populations, Interventions, Comparators, Outcomes, Timing, and Settings RCT Randomized … Clinical Trial SEADS Supplemental Evidence and Data for Systematic Reviews U.K.

1099. Research White Paper Managing Missing Data in Patient Registries Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
      February 01, 2018 - accounted for in analyses to the extent possible (known as informative censoring in the context of randomized … Additionally, while randomized clinical trials (RCTs) often limit their samples to a narrow and often

1100. Making Healthcare Safer IV: Programs for Responding to Harms Experienced by Patients during Clinical Care (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/clinical-care-protocol.pdf
      January 01, 2024 - 7 Study Parameter Inclusion criteria Exclusion criteria Type of studies Systematic reviews, randomized … controlled trials, and observational studies with a comparison group, including pre- post studies … the primary reviewer will use the Cochrane Collaboration’s tool for assessing the risk of bias of randomized … controlled trials (RCTs) or the ROBINS-I tool for assessing the Risk Of Bias In Non-randomized Studies … performance bias, detection bias, attrition bias, reporting bias, and other bias.27 When assessing non-randomized