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Total Results: 1,524 records

Showing results for "randomized controlled trial".

1061. home-based-care-protocol-141119 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/home-based-care_research-protocol.pdf
      November 19, 2014 - Controlled Trials • High quality observational studies including: comparative cohort studies … Study Designs: We will include studies that evaluate the effect of HBPC interventions, including randomized … controlled trials (RCTs) and high quality observational studies such as comparative cohort studies … Randomized trials and observational studies will be evaluated according to criteria recommended in the … controlled trials.

1062. Nursing-Staff-Shortages-Rapid-Research-Appendix-C (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/nursing-staff-shortages-rapid-research-appendix-c.xlsx
      January 01, 2024 - Clinical RNs 2010 to 2020 PubMed and CINAHL 34 US Descriptive (n=27) Qualitative (n=1) Non-randomized … Cluster-randomized, pre- and posttest, controlled trial using parallel-groups (n=1) Quasiexperimental … Pre-posttest design( n=5) Mixed methods preposttest design (n=2) One group preposttest design (n=1) Randomized-controlled … experimental study (n=1) Mixed-method cluster randomized controlled trial with matched pairs randomization … Cochrane risk-of-bias tool for randomized trials – version 2 (RoB-2) tool for randomized studies and

1063. Executive Summary: Peripheral Nerve Blocks for (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-nerve-blocks-final-exec-sum.pdf
      August 01, 2025 - surgery is limited and mostly of insufficient or low strength largely due to high risk of bias in randomized … controlled trials (RCTs).

1064. Disposition of Comments Report for Local Therapies for Unresectable Primary Hepatocellular Carcinoma (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer-therapy_disposition-comments.pdf
      May 24, 2013 - Llovet’s randomized trial in 2002, Llovet did include a TAE arm and showed no difference in survival … versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled … trial. … versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled … trial, Lancet. 2002 May 18;359(9319):1734-9.

1065. Evidence Summary for CER 239: Acute Treatments for Episodic Migraine (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/cer-239-acute-migraine-evidence-summary.pdf
      December 01, 2020 - migraine-treatments/protocol 3 Key Question (KQ) 1: Opioid Therapy • Fifteen studies (13 randomized … controlled trials [RCTs] and 2 comparative observational studies) with 2,208 patients were included … Limitations For many interventions, very few or a single trial were available and most were small,

1066. Disposition of Comments for Imaging Tests for the Staging of Colorectal Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_disposition-comments.pdf
      November 20, 2014 - Peer Reviewer 4 Methods Table 12: what is a retrospective controlled trial? … controlled design. … Furthermore, we suggest mentioning the PETCAM trial, as this randomized controlled trial seems to lack … Survival analysis of PETCAM: a multicenter randomized controlled trial of PET/CT versus no PET/CT for … The PETCAM trial has not been published yet.

1067. Disposition of Comments Report for Strategies To Reduce Cesarean Birth in Low-Risk Women (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_disposition-comments.pdf
      January 01, 2010 - Team midwifery care in a tertiary level obstetric service: a randomized controlled trial. … trial of 1299 women. … To be a site in a randomized trial, at minimum, the leadership of units involved was invested in the … In the included randomized studies, trial assignment could not possibly be masked at all levels - sites … We agree that unlike in placebo controlled trials, the "comparator" is varied.

1068. Obesity-Child Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/obesity-child_executive.pdf
      March 31, 2010 - We included only randomized controlled trials (RCTs), quasi-experimental studies, and natural experiments … characteristics of the enrolled subjects, described the intervention clearly, described the main findings, randomized … One quasi-experimental study included only female adolescents and the other study randomized adolescents

1069. Vitamin D and Calcium: A Systematic Review of Health Outcomes (Update) (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/vitamin-d-calcium_executive.pdf
      September 01, 2014 - primary studies using a three-grade system (A, B, or C), evaluating each type of study design (i.e., randomized … controlled trial or RCT, cohort, and nested case-control). … NICHD) and Thrasher Research Fund Vitamin D3 Supplementation studies—in which pregnant women were randomized … Colorectal Polyps The B-rated WHI trial identified for the original report was the only trial of combined … Vitamin D supplementation during pregnancy: double-blind, randomized clinical trial of safety and effectiveness

1070. Disposition of Comments_Blood-Based Tests for Multiple Cancer Screening: A Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-disposition-comments.pdf
      May 14, 2025 - The fact that KQ4 required a randomized study (top of page 23) makes sense, but may need to be re-emphasized … We have revised the text to further emphasize that controlled studies were required for eligibility … It makes a great deal of sense to collect and monitor these data in randomized studies so that if … This would include controlled cohort studies. … The Consortium noted that “randomized controlled trials(RCTs) with mortality endpoints, which are the

1071. Glaucoma-Treatment Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-treatment_executive.pdf
      April 01, 2012 - controlled trials and quasi- randomized controlled trials of medical, laser, and incisional surgical … and quasi-randomized controlled trials. … High-quality randomized controlled trials have also shown that reduction of intraocular pressure slows … The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive … Early Manifest Glaucoma Trial Group. Natural history of open-angle glaucoma.

1072. #05 DEPRESSION (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_2012-12-10.pdf
      January 01, 2012 - trial design and outcomes thus far. … for an FDA IDE trial. 18-20 Investigators concluded from a 2010 Reclaim DBS Therapy trial of 10 … Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled … add-on trial. … Controlled substance schedules. [internet].

1073. Back-Pain-Imaging Clinician (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-imaging_clinician.pdf
      April 01, 2016 - Since the study was not randomized or double-blinded, there was also potential for confounding by study … of the cauda equina syn- drome, or severe or progressive neurologic deficits. »» Imaging after a trial

1074. Disposition of Comments for Comparative Effectiveness Review 133 Transitional Care Interventions To Prevent Readmissions for People With Heart Failure (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_disposition-comments.pdf
      May 27, 2014 - Correct. 43 Peer Reviewer 14 General The authors identified 47 randomized controlled trials. … controlled trials are included. … Although the non- randomized comparative studies and observational studies were deemed eligible, none … Correct-no non-randomized or observational studies were eligible. 111 TEP Reviewer 4 Methods Comparators … The one trial assessing a higher intensity intervention showed efficacy1 while the one trial assessing

1075. Disposition of Comments Report for Comparative Effectiveness of Bariatric Surgery and Nonsurgical Therapy in Adults With Metabolic Conditions and a Body Mass Index of 30.0 to 34.9 kg/m2 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-loss-surgery_disposition-comments.pdf
      June 05, 2013 - When we examine the emerging scientific literature on the subject, there are a modest number of randomized … However, it is difficult to do randomized trials of surgery and the report concludes it would be nice … Therefore, in selected patients with inadequately controlled diabetes or other metabolic conditions … randomized trials) evaluating the effects of bariatric surgery in diabetic patients with BMI < 35. … None needed OAC General Therefore, in selected patients with inadequately controlled diabetes or

1076. Disposition of Comments CER 214 Stroke Prevention in Patients With Atrial Fibrillation (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-214-afib-disposition-comments.pdf
      October 30, 2019 - For example, the ratio between persistent/permanent and paroxysmal AF differed from trial to trial. … trial. … Newly identified events in the RE-LY trial. … An open- label, randomized, controlled, multicenter study exploring two treatment strategies of rivaroxaban … in Atrial Fibrillation Trial).

1077. #14 SUBSTANCE ABUSE (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/14_substance_abuse_potential_high_impact_2012-12-11.pdf
      January 01, 2012 - A larger trial is planned. … the National Clinical Trials database, the program’s developers state that they are conducting a randomized … , controlled trial that will investigate the Text2Quit program combined with the Smokefree.gov program … treating opioid dependence. 15,16 Buprenorphine falls into the Schedule III drug class under the Controlled … 2011 press release, the manufacturer stated that data from the phase III, placebo- and active-drug-controlled

1078. App-D-Surv-Report-2-Noninvasive-Nonpharma (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-2-noninvasive-nonpharma.xlsx
      January 01, 2021 - Veteran Affairs Rehabilitation Research and Development (Grant #RX000474) Fair Groessl 2020 [same trial … participation in standard back school training and psychotherapy, 4) participation in another clinical trial … Spanish language; and (3) providing the exclusion criteria: (1)participation in a concurrent treatment trial … for Complementary and Integrative Health of the National Institutes of Health Fair Joyce 2021 [same trial … Roseen 2020 [same trial as Saper 2017; subsequent publication] See above. See above. See above.

1079. App-D-Surv-Report-1-Noninvasive-Nonpharma 0 (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-1-noninvasive-nonpharma_0.xlsx
      January 01, 2021 - Veteran Affairs Rehabilitation Research and Development (Grant #RX000474) Fair Groessl 2020 [same trial … participation in standard back school training and psychotherapy, 4) participation in another clinical trial … Spanish language; and (3) providing the exclusion criteria: (1)participation in a concurrent treatment trial … for Complementary and Integrative Health of the National Institutes of Health Fair Joyce 2021 [same trial … Roseen 2020 [same trial as Saper 2017; subsequent publication] See above. See above. See above.

1080. Development and Usability Testing of EPC Evidence Review Dissemination Summaries for Health Systems Decisionmakers (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-usability-testing.pdf
      November 01, 2018 - Anxiety disorders, Substance use disorder, Posttraumatic stress disorder: No controlled studies were … controlled trial; RR = risk ratio; SGA = second-generation antipsychotics; SMD = standardized mean difference … controlled trials 2 controlled clinical trials 1 cohort study 1 interrupted time series 7 studies evaluated … workshops for implementing an evidence- based practice Substance use disorders 12 to 17 years Controlled … primary care compared to referral to an external program Externalizing behaviors 2 to 12 years Controlled