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Total Results: 1,524 records

Showing results for "randomized controlled trial".

1041. Treatments for Basal Cell and Squamous Cell Carcinoma of the Skin - Executive Summary (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-199-skin-cancer.pdf
      December 01, 2017 - Many comparisons were evaluated in one or two randomized controlled trials only. … controlled trials (RCTs) and all comparative nonrandomized controlled studies (NRCSs) that took steps … controlled trial; NRCS = nonrandomized comparative study 6 The studies primarily reported on BCC … Clinical Trial. … controlled trial.

1042. Cer-254-Rural-Telehealth-App-E (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-254-rural-telehealth-app-e.xlsx
      January 01, 2021 - Risk of bias assessment: randomized controlled trials Author, Year Randomization Adequate? … Groups Similar or Controlled for Important Baseline Differences?

1043. Microsoft Word - Comparative_Effectiveness_Research_Review_Disposition_of_Comments_Report_Final_120710_refs_delinked1.docx (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_disposition-comments.pdf
      November 01, 2010 - This lack of balance may be due in part to the small size of the trial (n=23). … I take it the authors are using data from the 7 prospective studies or non-randomized trials to make … In a single study, the most appropriate design is a randomized control trial in which the size of between-group … For example, why did the raters conclude that Sallows and Graupner (2005 randomized correctly, whereas … This reviewer interprets this design in the context of a treatment study as a "non- randomized pre-post

1044. PowerPoint Presentation (ppt file)
      effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-frameworks.ppt
      June 01, 2012 - controlled trial results) is rare. … Direct evidence of a test’s effect on outcomes, usually in the form of randomized controlled trials, … Using the principles of randomized controlled trial design to guide test evaluation. … Using the principles of randomized controlled trial design to guide test evaluation. … Using the principles of randomized controlled trial design to guide test evaluation.

1045. PowerPoint Presentation (ppt file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-frameworks.ppt
      June 01, 2012 - controlled trial results) is rare. … Direct evidence of a test’s effect on outcomes, usually in the form of randomized controlled trials, … Using the principles of randomized controlled trial design to guide test evaluation. … Using the principles of randomized controlled trial design to guide test evaluation. … Using the principles of randomized controlled trial design to guide test evaluation.

1046. Traumatic Brain Injury and Depression (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-brain-injury_executive.pdf
      April 01, 2011 - The study on sertraline was a double-blind placebo controlled trial with block randomization, in which … Randomized treatment trial in mild traumatic brain injury. … Community based rehabilitation after severe traumatic brain injury: a randomised controlled trial. … Routine follow up after head injury: a second randomised controlled trial. … A randomized controlled trial of sertraline for the treatment of depression in persons with traumatic

1047. #06 Developmental Delays ADHD, and Autism (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1312.pdf
      December 01, 2013 - For example, clinical trial investigators at the Children’s Hospital of Philadelphia indicate that … A randomized, controlled trial of intranasal oxytocin as an adjunct to behavioral therapy for autism … An open-label trial of oxytocin in adolescents with autism spectrum disorders. … Intranasal oxytocin versus placebo in the treatment of adults with autism spectrum disorders: a randomized … controlled trial.

1048. Comparative Effectiveness of β-Adrenergic Antagonists on the Risk of Rehospitalization in Adults with Heart Failure (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-rehospitalization_research.pdf
      November 01, 2007 - Placebo-controlled randomized trials have demonstrated the efficacy of selected β- blockers on outcomes … The COMET randomized trial compared carvedilol (25 mg per day) against metoprolol tartrate (50 mg twice … A small randomized, non-blinded trial in Serbia of 150 patients with heart failure being treated with … with heart failure: the Metoprolol CR/XL Randomized Intervention Trial in congestive heart failure … (COMET): randomised controlled trial.

1049. Maternal and Fetal Effects of Mental Health Treatments in Pregnant and Breastfeeding Women: A Systematic Review of Pharmacological Interventions (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/protocol-pharm-pregnant-women_0.pdf
      December 05, 2018 - This literature has two important challenges: lack of trial data leading to reliance on observational … of randomized controlled trials to inform clinical decisionmaking.27 Trial evidence on psychotropic … ., internal validity), we will use the ROBINS-141 tool for observational studies and the Cochrane randomized … controlled trial (RCT) tool42 for RCTs (if we find any eligible trials). … Brexanolone (SAGE-547 injection) in post-partum depression: a randomised controlled trial.

1050. Disposition of Comments Report for CER 132 Combination Therapy Versus Intensification of Statin Monotherapy: An Update (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_disposition-comments.pdf
      September 01, 2014 - increased cIMT in the ezetimibe group, observed in a post-hoc analysis of a subset of the originally randomized … Fourth, the results of two large placebo-controlled outcomes trials belie any adverse effect on ischemic … In the types of randomized controlled trials identified in this analysis, adherence is optimized to … We added text to the methods to clarify how cross-over trials were considered: “We considered randomized … All studies that have looked at combo vs. mono therapy have been with a controlled LDL goal as the

1051. Evidence Report on the (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-psoriatric_research-protocol.pdf
      December 06, 2010 - biologic agents were introduced; management options tended to be adapted from rheumatoid arthritis (RA) trial … evidence (study design and other criteria) Original research; eligible study designs include: • Randomized … controlled trials (RCTs) with a sample size of equal to or greater than 100 • Nonrandomized controlled

1052. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-adolescents_research-protocol.pdf
      March 29, 2011 - And for randomized controlled trials, was there an intent-to-treat analysis? … country, city, state) and time period, population description, sample size, and study type (e.g., randomized … controlled trial, prospective observational study, etc.). … we will organize results by study design, with a focus on those designs less subject to bias (i.e., randomized … controlled trials, controlled trials), those studies rated as higher quality in our quality assessment

1053. Carbohydrate-Intake-Prepub-Final-Research-Table-Da (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-prepub-final-research-table-da.xlsx
      January 01, 2019 - Qualitative/quantitative; survey; interview; focus group; cohort study; case-control; RCT N randomized … exposure concisely N analyzed Describe comparator concisely N analyzed List confounders and covariates in controlled … age, smoking during pregnancy, 2-h OGTT plasma glucose value, energy intake, offspring sex The TOP trial … ) Australia NR Inclusion: Overweight and obese pregnant women with complete data enrolled in SPRING trial … controlled trial SD standard deviation SE standard error SPRING Study of Probiotic IN Gestational

1054. Disposition of Comments for CER 171 Noninvasive Testing for Coronary Artery Disease (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/coronary-artery-disease-testing_disposition-comments.pdf
      March 29, 2016 - Risk difference (RD) provides an absolute measure for randomized controlled trial data. … Trial. … Diagnostic performance and cost of CT angiography versus stress ECG--a randomized prospective study … Relations and Advocacy General Key References CCTA in the Symptomatic Stable Chest Pain – Large Randomized … A randomized, multicenter, multivendor study of myocardial perfusion imaging with regadenoson CT perfusion

1055. Disposition of Comments for CER 165 Fecal Incontinence (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/fecal-incontinence_disposition-comments.pdf
      March 21, 2016 - , controlled study. … Standard compared with mnemonic counseling for fecal incontinence: a randomized controlled trial. … controlled trial. … Problems with this are noted in my earlier comment about the Heymen trial of stepped therapy. … =page; RCT= randomized controlled trial; TEP=Technical Expert Panel Source: https://www.effectivehealthcare.ahrq.gov

1056. Therapies for Clinically Localized Prostate Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_clinician.pdf
      January 01, 2016 - † Two large randomized controlled trials compared RP and WW and reported health outcomes. … Prostate Cancer Group-4 (SPCG-4) study (N = 695) and the Prostate Cancer Intervention Versus Observation Trial … patients with PSA-detected prostate cancer and examine patient- focused outcomes –– An ongoing clinical trial

1057. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/trauma-interventions-maltreatment-child_research-protocol.pdf
      January 12, 2012 - Study inclusion criteria Category Criteria for inclusion Study design Systematic reviews, randomized … controlled trials, nonrandomized controlled trials, prospective and retrospective cohort studies, and … Controlled Trial"[Publication Type] OR "Randomized Controlled Trials as Topic"[Mesh] OR "Single-Blind … Search #31 AND #42 #44 Search "Case-Control Studies"[Mesh] #45 Search #31 AND #44 #46 Search "trial … Methods for identifying grey literature will include a review of trial registries, specifically ClinicalTrials.gov

1058. Disposition of Comments Report for Treatment for Hepatitis C Virus Infection in Adults (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_disposition-comments.pdf
      November 27, 2012 - As stated on Page 8, the CER included randomized trials for all key questions. … We did include the Marcellin trial in a sensitivity analysis. … an early virological response and were actually randomized to different treatments and analyzed. … Results (p.48) The sentence “A trial of extended early virologic responders…randomized to 4 compared … In the ILLUMINATE Trial patients with an early virological response were randomized at week 20 to either

1059. Comments to Effective Heath Care Program Draft Documents (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/registries-guide-2nd-edition_disposition-comments.pdf
      March 03, 2010 - By definition, pregnant women would not be 'randomly' exposed postapproval except in a clinical trial … disease and a first product with proven efficacy, it would not be ethical to randomize patients in a trial … pregnant women, or in populations where it may be difficult to accrue sufficient numbers of clinical trial … Page 18: A number of questions around stents have been addressed by a number of meta‐analyses of randomized … product will depend upon the size, duration, representativeness, and thoroughness of the clinical trial

1060. Ch 5-User-Guide-To-Ocer 130129 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
      January 01, 2012 - comparisons within the same indication may still result in confounding by severity when not adequately controlled … rates or outcome definitions over time could introduce bias into the analyses and must be adequately controlled … Comparator Selection “time-to-response” or immortal person-time bias if not adequately controlled.29 … Increasing levels of restriction in pharmacoepidemiologic database studies of elderly and comparison with randomized … trial results.