-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/screening-counseling-interventions-protocol-amendment.pdf
February 05, 2025 - impact of an implementation strategy
compared with no strategy or another implementation strategy
(randomized … controlled trials [RCT], nonrandomized controlled studies,
interrupted time series)
To assess the … FQHC = Federally Qualified Health Center; KQ = Key Question; RCT = randomized controlled trial; USPSTF … studies, we will use the Cochrane
Risk of Bias 2 (RoB 2.0) tool for RCTs,23 the Risk Of Bias In Non-randomized … Studies of Interventions (ROBINS-I) tool24 for nonrandomized controlled studies
of interventions with
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/presentations-future_research.pdf
April 01, 2012 - controlled trials, prospective
observational studies, health systems research, and dissemination of … controlled trials that were then underway and sought to identify potential studies and research … Because of the lengthy course of this disease, some randomized controlled trials
have been published … understandable from the
patient’s perspective but may greatly reduce the ability to draw conclusions from the trial … For example, while there may be randomized
controlled trials of screening, the question about the adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-nitrous-oxide_research-protocol.pdf
August 24, 2011 - literature related to non-human subjects, and publications not
resulting from some form of clinical trial … For randomized controlled trials, the fundamental
domains will include: adequate sequence generation … country, city, state) and time period, population
description, sample size, and study type (e.g., randomized … controlled trial, prospective
observational study, etc). … controlled
trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-child-interventions_disposition-comments.pdf
February 11, 2013 - I concur with the interpretation as a call “to action” for future
research (especially well-controlled … of certainty that
the harms were due to the intervention
itself, since too many variables are not
controlled … We scoped our review to include any well-
designed study that adequately controlled
for confounding … Randomized trial comparison of emotion regulation and relational
psychotherapies for PTSD with girls … [Comparative
Study Randomized Controlled Trial Research Support, U.S. Gov’t, Non-
P.H.S.].
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/abnormal-uterine-bleeding_research-protocol.pdf
November 21, 2011 - For all Key Questions, we will include data from controlled
clinical trials (e.g., randomized controlled … The following designs will be
considered for inclusion: randomized controlled trials
For Key Question … use existing tools with established validity and
reliability to assess methodological quality of randomized … controlled trials and
observational studies. … Randomized controlled trials will be assessed using the
Cochrane Risk of Bias Tool.
39
This tool
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_executive.pdf
June 01, 2012 - criteria were met:
• Original data or related methodology paper of
an included article
• Randomized … controlled trial, prospective or
retrospective observational study, or registry
• Not a systematic … Randomized trials comparing functional versus
anatomic modalities. … Stress
echocardiography in the evaluation of women presenting with
chest pain syndrome: a randomized … Artery Disease: Results From
the What Is the Optimal Method for Ischemia Evaluation in
Women (WOMEN) Trial
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hemorrhage-postpartum_disposition-comments.pdf
April 28, 2015 - Most
studies were not of good quality and there were few
randomized controlled trials. … In the cluster randomized trial, could it be that
passive diffusion protocols in the control arm of … This point can be a concern in some
cluster randomized designs. … Thus, we did not have
concerns about contamination of the
control group for this trial. … Peer reviewer #1 Results Does this intervention [Page 66. cluster randomized
trial] really test the
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-decision-modeling.ppt
June 01, 2012 - Well-run randomized trials or nonrandomized studies can provide this evidence as long as the studies … Using the principles of randomized controlled trial design to guide test evaluation. … First, randomized trials may exist that suggest the treatment response is the same. … Using the principles of randomized controlled trial design to guide test evaluation. … Using the principles of randomized controlled trial design to guide test evaluation.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-decision-modeling.ppt
June 01, 2012 - Well-run randomized trials or nonrandomized studies can provide this evidence as long as the studies … Using the principles of randomized controlled trial design to guide test evaluation. … First, randomized trials may exist that suggest the treatment response is the same. … Using the principles of randomized controlled trial design to guide test evaluation. … Using the principles of randomized controlled trial design to guide test evaluation.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-271-mental-health-pregnant-disposition-comments.pdf
July 31, 2024 - Given this is perinatal mental health a
rationale is not given for excluding open trial
studies. … controlled pilot trial. … A community-based randomized
controlled trial of Mom Power parenting
intervention for mothers with … Controlled Trial. … This
could include randomized
controlled trials (RCT) as
well as participatory
models and translation
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1412.pdf
December 01, 2014 - In the CLEAR1 trial, patients given lesinurad 200 mg or 400 mg, and 54% and 59%,
respectively, achieved … 6, compared with 28% of
patients treated with allopurinol and placebo (p<0.0001).5 In the CLEAR 2 trial … number of gout flares or
number of patients with complete tophus resolution.8
In the phase III, randomized … , double-blind CRYSTAL trial (n=324), patients with gout, sUA
levels of 6.0 mg/dL or more, and at least … and febuxostat did not achieve a statistical
improvement at month 6 (p=0.13).6
In the phase III, randomized
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2022-update-app-g1.xlsx
January 01, 2022 - RoB judgement 2.1) Were ppts aware of their assigned intervention during the trial? … carers and people delivering the interventions aware of participants' assigned intervention during the trial … masking carers or ppts) were there deviations from the intended intervention that arose because of the trial … substantial impact (on the result) of the failure to analyse participants in the group to which they were randomized … RoB judgement 3.1) Were data for this outcome available for all, or nearly all, participants randomized
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_clinician.pdf
July 01, 2017 - hazard ratio; Inst = institutional cohort studies; N = number of subjects; NA = not applicable; RCT = randomized … controlled trial;
RR = risk ratio; SEER = Surveillance, Epidemiology, and End Results; SOE = strength … estimated glomerular filtration rate;
ESRD = end-stage renal disease; N = number of subjects; RCT = randomized … controlled trial; Ret = retrospective study;
RR = risk ratio; SOE = strength of evidence; WMD = weighted
-
effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
June 01, 2013 - patients
with CF who have two copies of the CFTR-F508del mutation, according to recent phase II
trial … In a randomized controlled trial, patients with COPD (n=1,577 ) who were at increased
risk of exacerbations … In a
randomized, double-blind, placebo-controlled, phase III trial, cosponsored by the Cystic Fibrosis … patients with CF who have two copies of the CFTR-
F508del mutation, according to recent, phase II trial … : In a randomized controlled trial, patients with COPD who were at increased risk
of exacerbations
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-204-obesity-disposition-comments.pdf
December 01, 2017 - The extent to which each of the studies considered were pre-
registered (or registered at all) in a trial … in the
Table footnotes
Reviewer #4: Results, KQ3
“Of the 44 experimental studies (RCTs and non-randomized … controlled trials) reporting on children’s diet, 15 reported the
outcome based on 24-hour recall, … Reviewer #4: Results, KQ4 I do not understand the definition of controlled
clinical trial as it is … In controlled clinical trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-3-noninvasive-nonpharma_0.xlsx
January 01, 2022 - Poor
Garrido-Ardila 2021
[same trial as Garrido-Ardila 2020; subsequent publication]
[Surveillance … Veteran Affairs Rehabilitation Research and Development (Grant #RX000474)
Fair
Groessl 2020
[same trial … for Complementary and Integrative Health of the National Institutes of Health Fair
Joyce 2021
[same trial … Marshall 2021
[same trial as Saper 2017; subsequent publication]
[Surveillance Report 3] U.S. … Complementary and Integrative Health of the National Institutes of Health Fair
Roseen 2020
[same trial
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-surgical-report-cards.pdf
November 01, 2023 - No
randomized trials were identified. … We did not identify any randomized controlled trials for
inclusion. … controlled
trials. … ): design and rationale of a
nationwide stepped-wedge cluster-
randomized trial. … trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_disposition-comments.pdf
May 29, 2013 - Thanks to
their inclusion of many studies with designs other than just randomized controlled
trials … Overall, only 2 randomized trials were found for all of the KQs (neither high quality). … Although we included study
designs other than randomized controlled
trials in our review, the identification … and
indexing of observational studies is far
more challenging than that of randomized
controlled … We agree and have revised this to suggest
that a trial of IVCF may not be warranted.
-
effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1506.pdf
June 01, 2015 - Experts thought that available clinical trial data
indicated interactive text-messaging’s efficacy … Six-months outcomes of a randomised trial of
supportive text messaging for depression and
comorbid … A
randomized controlled trial of a text-messaging
intervention promoting protective behavioral … A text
message alcohol intervention for young adult
emergency department patients: a randomized … clinical trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-search-strategies.ppt
June 01, 2012 - databases (e.g., SciVerse Scopus or Web of Science )
Unpublished or “grey” literature, such as:
Clinical trial … or the Web of Science, and, if appropriate, the grey literature including sources such as clinical trial … indexing of medical test studies may improve, in much the same way as the reporting and indexing of randomized … Fourth, it is important not to rely on controlled vocabulary alone. … vocabulary:
A controlled vocabulary may not contain all variants.