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Total Results: 1,519 records

Showing results for "randomized controlled trial".

1001. Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-disposition.pdf
      June 22, 2017 - controlled trials (RCTs) to increase the likelihood that the trial outcome will favor the sponsor’ … This is the largest VTE prophylaxis randomized clinical trial in orthopaedic surgery with over 17,000 … This is why this trial did not meet criteria. … Jiranek, MD, FACS) Methods Pooled analyses of randomized controlled trials allow the comparison … This large randomized trial is considered Level I evidence in support of mechanical prophylaxis.

1002. VTE Surveillance Assessment_49_low_SPI (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_surveillance.pdf
      December 01, 2012 - filters were not applied to any of the searches although the Cochrane Central Register only contains randomized … or controlled clinical trials. … venous thrombosis; VTE: venous thromboembolism; PE= pulmonary embolism; OR= pulmonary embolism; RCT=Randomized … Abbreviations: RCT=randomized controlled trial; pts=patients; yr(s)=years; NR=not reported; vs.= versus … CER=comparative effectiveness review; RCT=randomized controlled trial; pts=patients; yr(s)=years; NR=

1003. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-update_research-protocol.pdf
      May 07, 2010 - with treatment protocols that permitted the addition of other antihypertensive medications during the trial … We will search MEDLINE® (May 2006 to present) and the Cochrane Central Register of Controlled Trials … We will include English-language reports of controlled trials or cohort studies that compared an angiotensin … Comparators of interest, Outcomes, Timing, and Settings PVD Peripheral vascular disease RCT Randomized … control trial TC Total cholesterol TEP Technical Expert Panel TG Triglyceride VII.

1004. Disposition of Comments for CERs 155 156 Contast-Induced Nephropathy (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_disposition-comments.pdf
      January 07, 2016 - As far as I can tell, though, even though it is by far the largest randomized clinical trial (RCT) ever … the ACT trial, which says, “The implications of this adequately powered, well-conducted clinical trial … The meta-analysis included 63 randomized controlled trials which were mostly small and open label. … Circulation 2011, which was a well powered (n= 2308), multicenter, randomized, placebo controlled trial … This brings into question the results of at least 13 randomized, controlled trials that reported NAC

1005. Disposition of Comments Report for Comparative Effectiveness Review #68 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_disposition-comments.pdf
      July 01, 2012 - Preventive use of noninvasive ventilation after extubation: a prospective, multicenter randomized controlled … trial. … A randomized trial of noninvasive positive end expiratory pressure in patients with acquired immune … The study by Girault (VENISE Trial) must be interpreted carefully. … There is hence no difference between a quasi-randomized study and a randomized one that does not conceal

1006. Presentation of Future Research Needs (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/presentations-future_research.pdf
      April 01, 2012 - controlled trials, prospective observational studies, health systems research, and dissemination of … controlled trials that were then underway and sought to identify potential studies and research … Because of the lengthy course of this disease, some randomized controlled trials have been published … understandable from the patient’s perspective but may greatly reduce the ability to draw conclusions from the trial … For example, while there may be randomized controlled trials of screening, the question about the adverse

1007. Disposition of Comments Report for Evidence Report/Technology Assessment No. 214 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_disposition-comments.pdf
      February 25, 2014 - Of note, six of the 28 good and fair quality studies included in the review randomized fewer than 50 … In addition, the priority scores (100 to 500) for Trial I was 122 (5th percentile) and Trial II it … However, this study was not placebo controlled and although researchers may have been blind the participants … It would be good to insert randomized after 20 to show that the sampling was random. … It is surprising that breastfeeding was not controlled for in the analyses or addressed in the report

1008. Systematic Review of Intermittent Inhaled Corticosteroids and of Long-acting Muscarinic Antagonists for Asthma (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-pharmacologic-treatment_research-protocol.pdf
      December 27, 2016 - Category Inclusion Criteria Exclusion Criteria Setting All settings will be included None Study Design Randomized-controlled … If data cannot be abstracted after the first period, the trial will be included based on the following … Efficacy and safety of budesonide/formoterol pressurized metered-dose inhaler: randomized controlled … trial comparing once- and twice-daily dosing in patients with asthma. … The ROBINS-I tool (Risk of Bias in Non-randomized Studies – of Interventions), Version 7 March 2016.

1009. S158 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/s158.pdf
      October 01, 2007 - epidemiologic methods, propensity score calibration, research design (Med Care 2007;45: S158–S165) Randomized … controlled trials are often regarded as the most accurate method to assess treatment effects. … trials who are healthier and want to pursue a more healthful life style, the long time required from trial … erroneous because effect sizes, base- line risks, and comorbidity have been shown to differ be- tween trial … Principal results from the Women’s Health Initiative randomized con- trolled trial.

1010. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
      November 22, 2011 - ○ Randomized controlled trials of test-and-treat strategies ○ Nonrandomized comparative studies … Thus randomized controlled trials will be graded as having a high, medium, or low risk of bias, and … Appropriate methods will be used to account for crossover trial designs. 41 If performed, all meta … Various randomized designs can be used to evaluate medical tests. … with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial

1011. Microsoft Word - finbody.doc (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-artery-stenosis_research-2007.pdf
      January 01, 2007 - An analysis of a previously reported randomized trial that compared immediate angioplasty and either … While evidence from high quality randomized controlled trials (RCTs) was preferred, these data were … Among the RCTs of angioplasty versus medical therapy, only the SNRASCG randomized trial (Webster 1998 … A meta-analysis of randomized controlled trials. Am J Med. 2003;114:44-50. 26. … controlled trial RI Resistive index SBP Systolic blood pressure SCr Serum creatinine SNRASCG

1012. bipolar-disorder-treatment-protocol-140623 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
      June 23, 2014 - Trials (CENTRAL) to identify previous systematic reviews, randomized controlled trials, and prospective … Relevant grey literature resources include trial registries and FDA databases. … controlled trials as topic/ 34 randomized controlled trial/ 35 random allocation/ 36 double blind …  method/ 37 single  blind method/ 38 clinical trial/ 39 clinical trial, phase i.pt. 40 clinical … trial, phase ii.pt. 41 clinical trial,  phase iii.pt. 42 clinical trial, phase iv.pt. 43 controlled

1013. CERs Report cover (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/future05-breastcancer-10-5-2010final.pdf
      September 01, 2010 - Controlled Trials, Clinical Trial Results, WHO Trial Registries) and grant databases (NIHRePORTER, … studies, reviews) 185, 194, 195 SERMs (focus of original CER)e Randomized controlled trials … controlled trials I Observational studies 223 Gene-based drugs Randomized controlled trials … + diet; medications + aspirin Randomized controlled trials 52, 63, 226, 227 192, 228, 229 210 … controlled trial in osteoporotic postmenopausal women.

1014. Assessing the Quality of Individual Studies (ppt file)
      effectivehealthcare.ahrq.gov/sites/default/files/assessing-quality.ppt
      January 01, 2010 - quality of an individual study, the first step is to evaluate the study design and classify studies as randomized … Predefined Criteria for All Study Types (I) Commonly used tools can be found in the following publications: Randomized … controlled trials quality rating tools West S, King V, Carey TS, et al. … Collaborative Group and the European Carotid Surgery Trial Collaborative Group. … Collaborative Group and the European Carotid Surgery Trial Collaborative Group.

1015. Treatments for Schizophrenia in Adults: A Systematic (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
      January 01, 2017 - Randomized controlled trials were evaluated with criteria developed by the Drug Effectiveness Review … Cognitive behavior therapy for schizophrenia: a meta-analytical review of randomized controlled trials … A randomized controlled trial of cognitive-behavior therapy for persistent symptoms in schizophrenia … Cognitive therapy and recovery from acute psychosis: a controlled trial. 3. Five-year follow-up. … Results of a multisite randomized trial of supported employment interventions for individuals with

1016. Renal Artery Stenosis Management Strategies: An Updated Comparative Effectiveness Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-update_disposition-comments.pdf
      August 16, 2016 - Of greatest importance is that the update includes data from 3 randomized controlled trials (RCT’s … and non-randomized comparative studies. … We have added that the STAR trial was the only trial to explicitly include patients with CHF (~10%) … controlled clinical trials, rather than the results themselves, is refreshing and of crucial importance … clinical trials - those with a moderate degree of stenosis, blood pressure that can be controlled

1017. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-emergency_research-protocol.pdf
      July 18, 2011 - trial; NSAIDs = nonsteroidal anti-inflammatory drugs; RCT = randomized controlled trial. … This search will include trial registries such as ClinicialTrials.gov, metaRegister of Controlled Trials … controlled trials and nonrandomized controlled trials. 20 The tool examines six domains (sequence … controlled trials vs. nonrandomized controlled trials) and random effects versus fixed effects analyses … All trial groups will be considered separately in the analysis.

1018. PEPTIC ULCER #11 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1306.pdf
      June 01, 2013 - In the absence of randomized controlled trials or long-term outcomes data, some experts were uncertain … controlled trials. … , double-blind, placebo-controlled, phase III trial, investigators reported that 63% of patients (n … , double-blind, placebo-controlled, trial comparing teduglutide with placebo was conducted. … , placebo-controlled, clinical trials and two extension studies.36 Diffusion: A query of a U.S.

1019. breast-biopsy-update-130920 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_research-protocol.pdf
      September 20, 2013 - Studies must have been prospective or retrospective cohort studies or randomized controlled trials. … • Randomized controlled trials, cohort studies, and cross-sectional studies on patient preferences … This search will be adapted for use in MEDLINE®, EMBASE®, the Cochrane Central Register of Controlled … Thus, randomized controlled trials will be graded as having a high, medium, or low risk of bias, and … study/ or exp clinical trial/ or exp comparative study/ or cohort analysis or follow-up studies.de.

1020. Towards a Framework for Communicating Confidence in Methodological Recommendations for Systematic Reviews and Meta-Analyses (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methodological-recommendations-framework-communications_research.pdf
      September 01, 2013 - trial, but not in general –see reference 31, Robins JM, Scheines R, Spirtes P, et al. … Identification of randomized controlled trials in systematic reviews: accuracy and reliability of screening … controlled trial. … A randomized trial. … Effect of blinding and unmasking on the quality of peer review: a randomized trial.