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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_disposition-comments.pdf
    September 23, 2014 - These were designed with an orientation to producing optimal answers to important clinical questions … Similarly, the Key Questions themselves were developed to be clinically relevant based substantial … General Comments: the key questions are asked and the questions were not very surprising and are the … More than ten key sub-questions in fact could not be answered. This is true. … There were many Key Questions asked that could not be answered.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0129_07-13-2009.pdf
    January 01, 2009 -  When key questions have been drafted, they will be posted on the AHRQ Web site and open for public … : reduction of risk for/rates of emergency and/or medically unnecessary, planned cesareans Key Questions
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/public-reporting-cost-measures_disposition-comments.pdf
    March 05, 2015 - Reviewer #1 Guiding Questions a. … Together with AHRQ’s input, the authors posed a number of interesting questions, but can’t answer any … Reviewer #3 Guiding questions Page 6, Line 6: “out” should read “our” Thanks. … Reviewer#4 Minor issues Why “guiding questions” rather than “research questions”? … EPC procedure guide calls for the use of the term “guiding questions”. 56.
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/phenylketonuria_executive.pdf
    February 01, 2012 - Further, questions remain as to the empirical basis for the selection of specific blood Phe levels … Key Questions Key Questions were: Key Question 1a. … Using public input, we drafted final Key Questions, which AHRQ reviewed. … Analytic framework for treatment questions BH4 = sapropterin dihydrochloride; LNAAs = large neutral … Note: Numbers in circles indicate the positioning of Key Questions in the treatment process. 5
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/celiac-disease_research-protocol.pdf
    June 12, 2014 - The Key Questions AHRQ posted the Key Questions (KQ) on the Effective Health Care Website for public … This input is intended to ensure that the key questions are specific and relevant. … To improve clarity, we revised the language slightly and changed the order of the questions. … Review of Key Questions AHRQ posted the key questions on the Effective Health Care Website for public … This input is intended to ensure that the key questions are specific and relevant. IX.
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_surveillance.pdf
    July 01, 2014 - Release Date: August, 2012 Surveillance Report: August, 2014 Summary of Key Findings: • For Key Questions … • The original report conclusions for all Key Questions in this report are still valid. … Because we did not find any FDA black box warnings relevant to the key questions in this CER, we did … Identifying Qualitative Signals Appendix G shows the original key questions, the conclusions of the … For Key Questions 1, 2, 3, 4 and 6, new studies4-13, 17-20 were identified that may meet the inclusion
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ambulatory-safety_disposition-comments.pdf
    October 19, 2016 - The guiding questions are strong and stable throughout the brief. … The authors do not note any changes to the guiding questions. … #5 Guiding Questions Reasonable questions No response needed Peer Reviewer #2 General I also thought … The guiding questions may not be as good as they could be. … questions and the reasons for them are stated.
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-assessment-research-updates_research.pdf
    September 15, 2008 - Please visit the Web site (www.effectivehealthcare.ahrq.gov) to see draft research questions and reports … http://www.effectiveheathcare.gov/ 4 The assessment of the evidence base included the following questions … to those questions, and our questions regarding updating, and it asked the experts to offer their opinion … Experts who responded were sent the letter that incorporated key questions and conclusions for the report … Compilation of Findings For each CER, we constructed a summary table that included the key questions
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-treatment_research-protocol.pdf
    February 10, 2010 - The Key Questions We initially developed three key questions (KQs) with five subquestions to guide … Review of Key Questions For all EPC reviews, key questions were reviewed and refined as needed by … In addition, for Comparative Effectiveness reviews, the key questions were posted for public comment … Within the EPC program, the Key Informant role is to provide input into identifying the Key Questions … Therefore study questions, design and/or methodological approaches do not necessarily represent the
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/aggression_disposition-comments.pdf
    July 14, 2016 - We agree, and have added the following sentence to a list of important questions in the Executive Summary … The model helps a great deal and one can follow how the questions were derived. Thank you. … The odds of large well conducted studies addressing these questions is very low. … Our charge was to be able to address these key questions in a systematic review, and these questions … General Peer Reviewer #3 Questions are fairly well stated.
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia-2011_research-protocol.pdf
    January 01, 2011 - The Key Questions Based on the public comments, we have revised the Key Questions (KQs) and study … We will use separate forms for questions related to diagnostic test performance (KQ 2) and factors … Review of Key Questions For all EPC reviews, key questions were reviewed and refined as needed by … The EPC solicits input from Key Informants when developing questions for systematic review or when … Therefore study questions, design and/or methodological approaches do not necessarily represent the
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_disposition-comments.pdf
    January 15, 2016 - The key questions are clear and appropriate. Well done. … Questions not directly issues of effectiveness were considered contextual questions. … Questions were also posted to the AHRQ Effective Health Care web site for public input. … TEP reviewer #1 Key Questions The key questions are clearly stated, although I disagree with placing … The order of key questions is not indicative of their importance.
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0074_03-10-2009.pdf
    January 01, 2009 -  When key questions have been drafted, they will be posted on the AHRQ Web site and open for public … Key Questions from Nominator: None Considerations  The topic meets all EHC Program
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0277_03-10-2008.pdf
    January 01, 2008 -  When key questions have been drafted, they will be posted on the AHRQ Web site and open for public … Key Questions from Nominator: None Considerations  The topic meets all EHC Program
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_disposition-comments.pdf
    November 20, 2013 - Some answer the questions posed. We did not exclude data sets but studies. … The specification of the questions was detailed in the Methods section (chapter 2). … These questions will not affect the outcomes, but may help in interpreting the results. … Rev 8 General/ Methods The authors choose to do only meta-analysis for the accuracy questions. … Why for the accuracy questions alone?
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_disposition-comments.pdf
    March 10, 2010 - The CER presents the evidence addressing the key questions. … The CER presents the evidence addressing the key questions. … The CER presents the evidence addressing the key questions. … The CER presents the evidence addressing the key questions. … The CER presents the evidence addressing the key questions.
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-decision-support-tools_disposition-comments.pdf
    December 23, 2014 - The key questions are well defined and target important unanswered questions in the field. … Moreover, it attempts to answer several questions with differing methods. No action required. … Peer Reviewer #4 General Comments The key questions are appropriate and explicitly stated. … Conflicts and questions were resolved by discussion with a third reviewer.” … trials were found for both questions.
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_disposition-comments.pdf
    March 10, 2010 - s methodology and understands how the CER reached its conclusions for the three specific questions … The section on the scope of the key questions addresses this concern Introduction Page seven ? … While the EPC may The key questions addressed in this report were worded in a manner which enabled … dose statins, it is important to acknowledge that the EPC has, in fact, framed the key questions much … I think a table should be created for each of the three questions.
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ankyloglossia_research-protocol.pdf
    June 30, 2014 - The Key Questions Key Questions (KQ) were developed in consultation with Key Informants and the Task … While we received numerous comments from the public posting, modifications to the Key Questions were … Analytic Framework Figure 1 depicts Key Questions 1 and 4 within the context of the PICOTS described … Review of Key Questions AHRQ posted the Key Questions on the Effective Health Care Website for public … This input is intended to ensure that the Key Questions are specific and relevant. IX.
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-liver-metastases-therapies_research-protocol.pdf
    September 27, 2012 - The Key Questions Question 1 What is the comparative effectiveness of the various liver-directed … The Key Questions (KQs) were posted for public comment for 4 weeks. … Review of Key Questions For all EPC reviews, key questions were reviewed and refined as needed by … In addition, for Comparative Effectiveness reviews, the key questions were posted for public comment … Therefore study questions, design, and/or methodological approaches do not necessarily represent the

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