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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioids-chronic-pain-surveillance-report-1-final.pdf
    April 01, 2022 - (Key Questions and inclusion criteria are available in Appendix B.) … †Some studies were included for multiple Key Questions. … Key Questions and Inclusion and Exclusion Criteria ............................................ … Key Questions and Inclusion and Exclusion Criteria Key Questions Key Question 1. … Key Questions and Inclusion and Exclusion Criteria Key Questions Key Question 1.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-update_research-protocol.pdf
    May 07, 2010 - The Key Questions Question 1: For adult patients with essential hypertension, how do ACEIs, ARBs, and … Review of Key Questions For Comparative Effectiveness Reviews (CERs) the key questions were posted for … For other systematic reviews, key questions submitted by partners are reviewed and refined as needed … Therefore study questions, design and/or methodological approaches do not necessarily represent the … Review of Key Questions IX. Technical Expert Panel (TEP) X. Peer Review (Standard Language)
  3. CERs Report cover (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/hip-feature-treatment-future_research.pdf
    September 23, 2010 - Executive Summary Table 2 provides the rankings for these research questions. … Stakeholder ranking of research questions Item Rank 1. … Following refinement, the key questions addressed were: Key Question 1. … Table 3 provides the rankings for these research questions. … gap areas that are not specifically identified within the key questions.
  4. effectivehealthcare.ahrq.gov/sites/default/files/c-diff-infections-nomination-140925.pdf
    February 19, 2014 - Topic Description Key Questions: Key Question 1: How do different methods for detection of toxigenic … Key questions are listed below. § KQ 1.
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-screening_research-protocol.pdf
    May 18, 2011 - The proposed Key Questions (KQs) and the Analytic Framework were posted for public comment on the EHC … Review of Key Questions For all EPC reviews, key questions were reviewed and refined as needed by … the EPC with input from the Technical Expert Panel (TEP) to assure that the questions are specific … In addition, for Comparative Effectiveness reviews, the key questions were posted for public comment … Therefore study questions, design and/or methodological approaches do not necessarily represent the
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-applicability.ppt
    June 01, 2012 - Key questions lack clarity. Studies are not specific to the key questions. … These challenges are lack of clarity in the key questions, studies that are not specific to the key questions … Key questions lack clarity How the test is to be used should be stated clearly in the key questions … Lack of clarity in the key questions can hinder decisions about which studies to include and which to … in the key questions.
  7. effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-applicability.ppt
    June 01, 2012 - Key questions lack clarity. Studies are not specific to the key questions. … These challenges are lack of clarity in the key questions, studies that are not specific to the key questions … Key questions lack clarity How the test is to be used should be stated clearly in the key questions … Lack of clarity in the key questions can hinder decisions about which studies to include and which to … in the key questions.
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/lifecycle-assessment-protocol.pdf
    August 23, 2023 - Guiding Questions The brief will be facilitated by guiding questions (GQs), documenting research and … The guiding questions will help formulate the overarching methods and facilitate the search strategy … The planned questions are documented in Table 1. … Table 1 Potential Key Informant Questions Topic Question Guiding questions • To fully assess … the current state of the science for this topic, are we asking the right questions?
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-adolescents_research-protocol.pdf
    March 29, 2011 - The Key Questions Our draft key questions (KQs; see Appendix A) were posted for public comment on … Comments on the draft questions addressed interventions, outcomes, and access to care and are summarized … Review of Key Questions For all EPC reviews, key questions were reviewed and refined as needed by the … In addition, for Comparative Effectiveness reviews, the key questions were posted for public comment … Therefore study questions, design and/or methodological approaches do not necessarily represent the
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/25th-anniversary-epc-brochure.pdf
    November 01, 2022 - This summary is intended to inform research funders, researchers, and policymakers about the types of questions … that need to be addressed and the types of studies necessary to address these questions.
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/health-information-exchange_research-protocol.pdf
    April 20, 2015 - The Key Questions The draft Key Questions (KQs) developed during Topic Refinement were available for … As the questions are broad and diverse, we anticipate that different types of evidence will be included … Given that several of the key questions expand the scope of inquiry beyond effectiveness and harms to … Revised order of Key Questions 6 and 7. … Therefore, study questions, design and/or methodological approaches do not necessarily represent the
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-applicability_methods.pdf
    July 01, 2012 - Challenges for reviews include: (1) lack of clarity in key questions about the intended applicability … Common Challenges Unclear Key Questions Key questions guide the presentation, analysis, and synthesis … Key questions should provide clear context for determining the applicability of a study. … In addition, key questions that do not distinguish the management context in which the test is being … − Organize data within key questions by presence/absence of key elements.
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-urinary-retention_research-protocol.pdf
    November 19, 2012 - Within questions about treatment effectiveness, additional uncertainty, surrounds the clinical relevance … The Key Questions The draft Key Questions developed during AHRQs Topic Refinement process were posted … The comments received suggested that changes to the scope of the draft Key Questions were not necessary … Review of Key Questions For all EPC reviews, key questions were reviewed and refined as needed by the … In addition, the key questions were posted for public comment and finalized by the EPC after review
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-introduction_methods.pdf
    July 01, 2012 - for classifying the types of medical test evaluation studies and their relationship to potential key questions … In this complex environment, researchers have tended to focus on narrow questions, such as the ability … of a preventive measure.11 Such a framework is useful in maintaining an orderly process, clarifying questions … The specific questions are depicted graphically by linkages that relate interventions and outcomes. … These linkages serve the dual purpose of identifying questions to help structure the literature review
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-update_research-protocol.pdf
    January 15, 2015 - The Key Questions Listed here are the original Key Questions (from 2006 and 2007), which remain unchanged … Arrows depict studies sought to  address key questions formulated  in  this report Abbreviation … Titles and abstracts will be screened to identify articles relevant to each Key Questions. … Review of Key Questions The key questions will be reviewed and refined as needed by the EPC with input … from the Technical Expert Panel (TEP) to assure that the questions are specific and explicit about
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0311_06-17-2008.pdf
    January 01, 2008 -  When key questions have been drafted, they will be posted on the AHRQ Web site. … Description Nominator: Health care professional association Nomination Summary: The nominator questions … other test results) Outcome(s): Diagnostic and prognostic accuracy of troponin for ACS Key Questions
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0367_11-08-2010.pdf
    January 01, 2010 -  When key questions have been drafted, they will be posted on the AHRQ Web site and open for public … efficacy of treatment, improvements in depressive symptoms, parenting skills, and quality of life Key Questions … A systematic review on this topic may clarify some key questions about screening and treatment, and
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0313_02-09-2009.pdf
    January 01, 2009 -  When key questions have been drafted, they will be posted on the AHRQ Web site and open for public … Description Nominator: Health care professional association Nomination Summary: The nominator questions … reduced stone formation, quality of life (including suffering and anxiety), costs, complications Key Questions
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_disposition-comments.pdf
    August 23, 2012 - The clearly defined key questions and outlined requirements for a study to evaluate those key questions … Key questions are appropriate and explicitly stated. … Shareholders were adequately involved in the formation of key questions. … The questions are important and the key questions are stated explicitly. Thank you. … Peer Reviewer #8 General The report does address the important questions.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-frameworks.ppt
    June 01, 2012 - Do the Key Questions reflect the needs of the stakeholders? … Reveals potential Key Questions along the way. Is developed in consultation with stakeholders. … Clarifying Key Questions by illustrating important decisional dilemmas. … Use additional organizational frameworks to: Categorize the Key Questions. … Identify which types of studies will address specific questions in the review.

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