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  1. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/for-patients-with-pku-there-is-now-a-pharmaceutical-drug-to-treat-this-condition-in-the-past-is-was-treated-by-medical-foods-that-eliminated-the-harmful-substance-phenylalanine-the-cost-of-the-new-drug-is-70k-year-the-cost-to
    June 17, 2009 - Suggestion Disposition [PDF · 102.9 KB] Briefly describe a specific question, or set of related questions
  2. effectivehealthcare.ahrq.gov/products/rheumatoid-arthritis-medicine/research-protocol
    December 06, 2010 - Many questions remain about the risks of these agents across a spectrum of adverse events—from relatively … The Key Questions (KQs) Question 1: For patients with RA, do drug therapies differ in their ability … These questions will be focused specifically on answering the KQs. … Review of Key Questions For comparative effectiveness reviews (CERs), the Key Questions were posted … For other systematic reviews, Key Questions submitted by partners are reviewed and refined as needed
  3. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-is-the-effectiveness-of-interventions-designed-to-support-children-in-transition-from-pediatric-care-to-adult-care-with-special-health-care-needs-ineffective-transition-planning-can-have-significant-negative-consequences
    January 07, 2013 - Topic Suggestion Disposition [PDF · 1.2 MB] Briefly describe a specific question, or set of related questionsQuestions arise about when, how, and if the children with special health care needs should transition
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/genitourinary-symptoms-protocol.pdf
    January 30, 2023 - The Key Questions Introduction: After discussion with key informants and our team’s content and methods … Review of Key Questions The EPC refined and drafted the key questions after review of the public comments … This input is intended to ensure that the key questions are specific and relevant. IX. … The Key Questions III. Analytic Framework IV. Methods A. … Review of Key Questions IX. Key Informants X. Technical Experts XI. Peer Reviewers XII.
  5. effectivehealthcare.ahrq.gov/products/case-management/research-protocol
    January 11, 2011 - PICOs and Key Questions Key questions (KQs) were drafted with input from Key Informants and posted … Summary of Protocol Amendments The original version of the Key Questions has the same scope as the … Review of Key Questions For all EPC reviews, key questions are reviewed and refined as needed by the … EPC with input from Key Informants and the Technical Expert Panel (TEP) to assure that the questions … Within the EPC program, the Key Informant role is to provide input into identifying the Key Questions
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_executive.pdf
    September 01, 2014 - Key Questions and Scope Key Questions The Key Questions are listed below. … used to address questions about harms and adverse events. … Only high-quality systematic reviews were included to address Key Questions 1a and 2a. … For comparative questions, we synthesized the evidence from the primary studies themselves. … The most common reason for exclusion was lack of relevancy to the questions.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/case-management_research-protocol.pdf
    June 06, 2011 - outcomes, the nomination was further scoped during topic refinement to produce more specific key questions … PICOs and Key Questions Key questions (KQs) were drafted by the EPC with input from Key Informants … Summary of Protocol Amendments The original version of the Key Questions has the same scope as the … Review of Key Questions For all EPC reviews, key questions are reviewed and refined as needed by … In addition, for Comparative Effectiveness reviews, the key questions are posted for public comment
  8. effectivehealthcare.ahrq.gov/sites/default/files/introduction.ppt
    January 01, 2010 - The Effective Health Care Program emphasizes that CE research must answer real questions by using the … Answering real questions means the research should be able to help health care consumers decide among … of questions must include stakeholder input. … How Does the Effective Health Care Program Answer Real-World Questions? … How Does the Effective Health Care Program Answer Real-World Questions?
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/introduction.ppt
    January 01, 2010 - The Effective Health Care Program emphasizes that CE research must answer real questions by using the … Answering real questions means the research should be able to help health care consumers decide among … of questions must include stakeholder input. … How Does the Effective Health Care Program Answer Real-World Questions? … How Does the Effective Health Care Program Answer Real-World Questions?
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/treatment-resistant-depression_research-protocol.pdf
    December 09, 2009 - The Key Questions 1. … Specifically, the first two key questions pertain to the efficacy and effectiveness of obtaining (KQ1 … Review of Key Questions For Comparative Effectiveness reviews (CERs) the key questions were posted for … Therefore study questions, design and/or methodological approaches do not necessarily represent the … Review of Key Questions IX. Technical Expert Panel (TEP) X. Peer Review (Standard Language)
  11. effectivehealthcare.ahrq.gov/products/antiplatelet-treatment/research-protocol
    November 22, 2011 - Settings—for all Key Questions All relevant care settings (e.g., primary and secondary care). … The predictive ability of each test is addressed in Key Questions 1b, 1c, 2b, and 2c. … The analytic validity of phenotypic tests will be considered in Key Questions 1a and 2a. … For Key Questions pertaining to effect modification (Key Questions 1c, 2c, and 3c) we will require that … Review of Key Questions For all Evidence-based Practice Center (EPC) reviews, Key Questions are reviewed
  12. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/for-patients-with-crohns-disease-what-treatments-or-therapies-alone-or-in-conjunction-with-one-another-provide-the-highest-rate-of-disease-management-with-the-lowest-risk-of-long-term-complications-particularly-in-young-women
    March 10, 2009 - Suggestion Disposition [PDF · 153.4 KB] Briefly describe a specific question, or set of related questions
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/inguinal-hernia_research-protocol.pdf
    August 15, 2011 - These mesh-specific issues are covered by specific Key Questions (see Key Questions below). … The Key Questions Ten initial Key Questions had been posted for public comment on the Web site of the … The final list of Key Questions is below. … For questions comparing interventions (i.e., all questions except the one on surgical experience), the … Review of Key Questions For all EPC reviews, key questions were reviewed and refined as needed by the
  14. effectivehealthcare.ahrq.gov/sites/default/files/study-eligibility-criteria.ppt
    January 01, 2000 - Before seeing the key questions, consider the categories of criteria that you will want to apply. … Exercise 1 Exercise 1: Basic PICOTS Questions What is the relevant population? … , timing, and setting) into practical questions for establishing criteria. … Exercise 1: No “Right” Answers There are no “right” answers to these questions. … Exercise 1: No “Right” Answers There are no “right” answers to these questions.
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/case-management_executive.pdf
    January 01, 2013 - This report summarizes the existing evidence addressing the following Key Questions: Key Question 1 … The Key Questions for the report were then revised and posted for public comment on the Agency for … Analytic framework Note: Numbers refer to Key Questions. 4 was limited to English language materials … Outcomes of Interest The outcomes of interests are specified in the Key Questions listed above. … Types of Studies We included randomized trials and observational studies pertinent to the Key Questions
  16. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/rt-bone-metatases-final-protocol.pdf
    February 10, 2022 - The Key Questions Provisional Key Questions, description of patients, interventions, comparators, … Key Questions: The Key Questions (KQs) for this review are as follows: KQ 1: What is the effectiveness … Contextual Questions: Following the methods of the U.S. … Contextual Questions We plan to follow the methods of the USPSTF to evaluate the contextual questions … Review of Key Questions The Agency for Healthcare Research and Quality (AHRQ) posted the Key Questions
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_research-protocol.pdf
    October 01, 2013 - The Key Questions Preliminary Key Questions (KQs) KQ 1: In patients undergoing imaging studies requiring … No changes have been made to the Key Questions since the questions were posted for public comment. … Analytic Framework: Examining Interventions to Prevent Contrast Induced Nephropathy, Key Questions 1 … We will include randomized controlled trials and prospective cohort studies for all key questions. … Review of Key Questions For all EPC reviews, key questions were reviewed and refined as needed by the
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-psoriatric_research-protocol.pdf
    December 06, 2010 - Like in RA trials, many questions remain about the risks of these agents across a spectrum of adverse … PICOTS criteria for the above key questions: • Population(s): • Adults with psoriatic arthritis … , study design, methods, and results, specifically focused on answering the key questions. … Review of Key Questions For comparative effectiveness reviews (CERs), the Key Questions are posted for … Review of Key Questions X. Peer Review
  19. effectivehealthcare.ahrq.gov/sites/default/files/lessons-transcript.pdf
    January 06, 2017 - You can see the number is the number of questions within scales. … We need to answer difficult questions like who’s responsible for this. … Those are important questions to address with communities. … a couple of thoughts before we turn to questions just to the point? … NORA: Thanks Penny and we’ve gotten some really good questions.
  20. effectivehealthcare.ahrq.gov/products/telehealth-acute-chronic/research-protocol
    February 16, 2017 - The Key Questions Below are the Key Questions for the systematic review (SR) and the Guiding Questions … The Key Questions for the SR are based on questions provided in the scope of work that accompanied the … The questions were reviewed, reorganized, and refined by the project team and revised after input from … The Guiding Questions for the DM were also included in the scope of work. … The topics, specific questions, and scope for the DM will be based on the literature triage and initial

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