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4321. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/phenylketonuria_research-protocol.pdf
      March 29, 2011 - The Key Questions We developed the key questions (KQ) for this review based on input from key informants … Key Questions KQ1a. … Review of Key Questions For all EPC reviews, key questions were reviewed and refined as needed by … Key Questions KQ1a. … Review of Key Questions For all EPC reviews, key questions were reviewed and refined as needed by the

4322. Transparency of Reporting Requirements: Effectiveness of Treatments Options for the Prevention of Complications and Treatment of Symptoms of Diabetic Peripheral Neuropathy (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research-protocol.pdf
      September 01, 2016 - Objectives Study Purpose: To address questions about how to access and integrate information fromClini … We will conduct a pilot study and prepare a report that addresses the following questions: 1. … The DPN review seeks to address two key questions with sub-questions.

4323. Disposition of Comments Report for The Clinical Utility of Fractional Exhaled Nitric Oxide (FeNO) in Asthma Management (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-197-fractional-exhaled-nitric-oxide-disposition-comments.pdf
      December 20, 2017 - The discussion follows the order of Key Questions. … We agree that the questions are important. … The Key Questions are also clearly defined, explicitly stated, and appropriate. … I think the authors can move KQ1e after KQ1a, then move the other questions down. … The key questions are stated explicitly and are appropriate.

4324. The Role of Immunotherapy and the Management of Asthma: Systematic Review (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy_research-protocol.pdf
      September 14, 2016 - For each topic, key questions meriting a systematic literature review were formulated. … The Key Questions (KQ) 1. … For all the Key Questions we will exclude cross-sectional studies and surveys. … Review of Key Questions AHRQ posted the key questions on the Effective Health Care Website for public … The activity domain contains 5 ‘patient-specific’ questions.

4325. Management of suspected opioid overdose with Naloxone by Emergency Medical Services personnel (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/emt-naloxon_research-protocol.pdf
      November 29, 2016 - The Key Questions The scope and key questions for this topic were developed by AHRQ in conjunction … with naloxone to a healthcare facility vs. non-transport • Outcomes for each question: o All key questions … Due to the expected small numbers of randomized controlled trials to address the Key Questions, we also … Review of Key Questions Not applicable to this project. IX. … Therefore study questions, design, and methodological approaches do not necessarily represent the views

4326. Rapid-Reviews-End-User White-Paper (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rapid-reviews-end-user_white-paper.pdf
      April 01, 2016 - Guiding questions included: a. … KIs felt that the key questions were often the most important part of the review. … If the key questions do not address what the user needs, the review is not very useful. …  KIs stressed the relevance of the key questions, noting that if the questions did not directly … Under what circumstances, for what questions, would end-users trust a rapid review product?

4327. PKU Surveillance Assessment_CER 56_Low (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/phenylketonuria_surveillance.pdf
      January 15, 2013 - Findings and Conclusions For this assessment we constructed a summary table that included the key questions … manufacturer.4 3.3 Identifying qualitative and quantitative signals Table 1 shows the original key questions … portion of the original report does not need updating Are there new data that could inform the key questions … BH4 sensitive patients did not increase their HRQoL (although responses to a set of supplementary questions … New Evidence: Are there new data that could inform the key questions that might not be addressed

4328. Disposition of Comments for Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic Treatment for Hospital-Acquired Pneumonia (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
      November 24, 2014 - Peer Reviewer #1 Methods Some questions on the risk of bias methods used. … Answers for key questions were presented with adequate details and precision. … Also, Key Questions 1-3 were clearly delineated. … The research questions are explicitly stated and the work is definitely meaningful. … In that way, similar key questions might be better answered in the future.

4329. Stem-Cell-Children Surveillance (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/stem-cell-children_surveillance.pdf
      October 29, 2012 - included 251 unique studies identified by using searches through August, 2011 and addressed six key questions … The key questions of the original CER were as follows: 1. … Qualitative signals See also Table 1 (Summary Table), Appendix B, and Evidence Table (Appendix C) Key questions … Quantitative signals See also Table 1 (Summary Table), Appendix B, and Evidence Table (Appendix C) Key questions … Safety surveillance alerts None of the received safety surveillance alerts was relevant to the key questions

4330. Surveillance & Identification of Triggers for Updating Systematic Reviews for the EHC Program (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/head-neck-cancer_surveillance.pdf
      August 01, 2012 - unique studies identified by using searches through the September 28, 2009 and addressed four key questions … The key questions of the original CER were as follows: 1. … Cycle 1 (November 2011) 17 as no comparative studies addressed these key questions 1 cohort … The strength of evidence is insufficient as no comparative studies addressed these key questions … The strength of evidence is insufficient as no comparative studies addressed these key questions

4331. Coronary-Artery-Stenting Executive (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
      February 01, 2013 - Methods Input From Stakeholders This project began with a topic refinement in which Key Questions … Key Questions Our review focused on five Key Questions: Key Question 1: In patients with CAD, what … Coronary angiography alone was the comparison of interest for Key Questions 1, 2, 3, and 5. … For Key Questions 4 and 5, head-to-head comparisons of two or more intravascular diagnostic techniques … There was insufficient evidence to answer two of the five review’s Key Questions.

4332. Effective Health Care (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0272_03-06-2008.pdf
      January 01, 2008 -  When key questions have been drafted, they will be posted on the AHRQ Web site and open for … Key Questions from Nominators: Nominator 1 (public payer): For each of the treatment options for … obstructive sleep apnea (CPAP, oral appliances, UPPP, and RFA), we ask the following questions: 1

4333. Disposition of Comments Report for Technical Brief 15 Transition Care for Children With Special Health Needs (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/children-special-needs-transition_disposition-comments.pdf
      June 17, 2014 - Reviewer 5 (TEP) Background- Guiding Questions So I believe your questions were sufficient and … As mentioned the guiding questions take a mostly pediatric perspective. … Overall the guiding questions are appropriate for the topic. … Peer Reviewer 8 Background- Guiding Questions The questions posed by the authors are appropriate … Peer Reviewer 12 Background – Guiding Questions The guiding questions are appropriate to the

4334. Blumenthal-notes-151008 copy-Teresa (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/blumenthal-presentation.pdf
      November 11, 2015 - We did   question   counting and  we saw that these women  had  more questions and  there … “I don't know if the reason  why I was so poorly informed  was because I didn’t ask enough   questions … And  after it’s all over I think to myself why didn’t I ask them more questions?” … somehow make it a social  norm that doctors ask patients about what’s important to them, or what questions … They can  go into these modalities and  ask questions that maybe they didn’t have time to have in

4335. Community Forum Deliberative Methods Demonstration: Evaluating Effectiveness and Eliciting Public Views on Use of Evidence--Executive Summary (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/deliberative-methods-demonstration-executive-131125.pdf
      November 01, 2013 - , and asked questions of their own. … Following discussion, the groups had the opportunity to generate questions to be addressed offline by … The research questions for the thematic analysis focused on three main topics related to the overarching … Below, we summarize findings for five research questions addressing the effectiveness of deliberation … The unit of analysis for research questions 1–4 is the individual participant and for research question

4336. Mass-Casualty-Events-Scarce-Resources Executive (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mass-casualty-events-scarce-resources_executive.pdf
      June 01, 2012 - This report addresses the following Key Questions: Key Question 1. … Analytic Framework Given the heterogeneity in key aspects of study design across the four Key Questions … Investigators at the Southern California Evidence-based Practice Center then refined the questions … For all four Key Questions, we included articles found in the peer-reviewed literature and grey literature … Because of the volume of studies describing tested strategies that were relevant to Key Questions 1

4337. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_disposition-comments.pdf
      September 01, 2011 - The key questions are appropriate and explicitly stated. Thank you. … Peer Reviewer #4 General Questions are clearly stated, and they seem (at least to me) the right questions … Peer Reviewer #7 General The key questions are appropriate and explicitly stated. Thank you. … Additional questions that might be included in the document include the following:  Given evidence … The questions are appropriate and well-defined.

4338. Evidence Report on the (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
      May 24, 2010 - The Key Questions Question 1: How do different methods for detection of toxigenic C. difficile to … These will be organized according to key questions. D. … Review of Key Questions For Comparative Effectiveness reviews (CERs) the key questions were posted for … Therefore study questions, design and/or methodological approaches do not necessarily represent the … Review of Key Questions IX. Technical Expert Panel (TEP) X. Peer Review (Standard Language)

4339. S29 (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/s29.pdf
      October 01, 2007 - Follow-up questions were asked as needed to clarify responses. … Some questions that were raised would not be answerable before instituting a study. … What questions would you have? What barriers would you foresee? … Subjects would have many questions about any pro- posed CRTs, ranging from general questions about the … need for the study to specific questions about implementation.

4340. Effective Health Care (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0068_01-30-2009.pdf
      January 01, 2009 -  When key questions have been drafted, they will be posted on the AHRQ Web site. … Key Questions from Nominator: 1. … literature available on this topic, it appears that a review may be able to address the nominator’s questions