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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan4/autism-spectrum-disorder-in-young-children-screening
June 20, 2013 - socioeconomic status) can be important modifiers of screening test performance; the USPSTF added a key question
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/SUHq3jffCaucDobFXKewQ_
February 01, 2013 - Data Synthesis
We assessed the aggregate quality of the body of evi-
dence for each key question as … RESULTS
Key Question 1
For children without obvious signs and symptoms of abuse
or neglect but potentially … Key Question 2
What are the adverse effects of behavioral interventions
and counseling to reduce harm … Summary of Evidence
Key Question Studies Design Limitation Consistency Applicability Overall
Quality … 1:
11 trials
Key question 2:
None
Abstracts of potentially relevant
articles identified through MEDLINE
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan102/chronic-obstructive-pulmonary-disease-screening-2016
May 15, 2014 - In response, a contextual question on the rescreening interval was added; the rescreening interval is
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/k-btyK4W2-v9KnemTK8WDx
September 14, 2021 - For additional
information see the USPSTF
Procedure Manual.16
Screening Effectiveness
Key Question … country
4 Non–English-language
1866 Citations excluded at title and abstract stage
KQ indicates key question … of PID for screening vs
home sampling (RR, 0.50 [95% CI, 0.23-1.08]).33
Risk Stratification
Key Question … , after adjust-
ing for age, sex, and number of sex partners.26
Diagnostic Accuracy of Tests
Key Question … Screening Harms
Key Question 4.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary52/vitamin-d-and-calcium-to-prevent-fractures-preventive-medication-2013
December 10, 2011 - outcomes, instead referring to the Ottawa evidence report (which is current up to 2005) 8 for this question … KQ = key question.
* Go to “Study Selection” section for detailed population of interest. … KQ = key question; RCT = randomized, controlled trial. … (overarching question)
Vitamin D supplementation vs. placebo*
Total cancer
2 RCTs ( n = 3577 … stones: HR, 1.17 (CI, 1.02–1.34)
25-(OH)D = 25-hydroxyvitamin D; HR = hazard ratio; KQ = key question
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/from-topic-nomination-to-clinical-practice-resources-overview.pdf
June 01, 2021 - Draft Research Plan includes criteria for the
types of evidence that will be reviewed for each
key question … Task Force Process Notes
Inclusion and exclusion criteria are
determined on a topic and key
question
-
www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-screening-for-breast-cancer/breast-cancer-screening-january-2016
January 11, 2016 - We assessed the aggregate internal validity (quality) of the body of evidence for each key question as … KQ = key question. … Of these 10,036 were excluded at the abstract level because they did not address a key question or only … Some studies may have addressed more than one key question, and the trials may have reported data in … † Generally effective randomization and comparable groups are assembled initially, but some question
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/cHbBWNok76hRWKDXXm3R2_
February 13, 2018 - lists,
peer reviewers)
1307 Excluded based on review of
title, abstract, or both
KQ indicates key question … Benefits of Screening
Key Question 1. … Screening Protocols for Trials Addressing Ovarian Cancer Mortality (Key Question 1)a
Source
Screening … with ovarian can-
cer did not differ significantly between study groups.21
Harms of Screening
Key Question … Effects of Ovarian Cancer Screening on Ovarian Cancer Mortality (Key Question 1)a,b
Source
Screening
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/RkowkNFvCYh9hMnEBcCkGh
May 01, 2004 - This update of the evidence, written in 2003,
focuses on the question of whether screening for
amblyopia … This question has been added to the
analytic framework from the original Systematic
Evidence Review ( … flaws noted in the “poor”
category below: generally comparable
groups are assembled initially but some
question
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary43/prostate-cancer-screening-2012
October 07, 2011 - Key Question 1: Does PSA-Based Screening Decrease Prostate Cancer–Specific or All-Cause Mortality? … Key Question 2: What Are the Harms of PSA-Based Screening for Prostate Cancer? … Key Question 3: What Are the Benefits of Treatment of Early-Stage or Screening-Detected Prostate Cancer … Key Question 4: What Are the Harms of Treatment of Early-Stage or Screening-Detected Prostate Cancer? … Of those, 11 studies were included for key question 1 and 27 studies were included for key question 2
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary39/obesity-in-children-and-adolescents-screening-2010
January 15, 2010 - Key Question 1 is: "Do weight management programs (behavioral, pharmacological) lead to body mass index … Arrow 2, which proceeds up and to the right, represents Key Question 2, which is: "Do weight management … Arrow 3 represents Key Question 3, which is "What are the adverse effects of weight management programs … From there, an arrow representing Key Question 2 proceeds to the right and forks in two directions. … One arrow, representing Key Question 3, curves down and ends at the oval reading "Adverse effects."
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/mk-eb9VtB_jx885wnjuzk3
January 01, 2024 - Benefits of Statin Treatment
Key Question 1a. … coronary heart disease;
CVA, cerebrovascular accident
(stroke); CVD, cardiovascular disease;
KQ, key question … Key Question 1b. … e For example, nonsystematic reviews; letters.
f Studies may be included for more than 1 key question … Key Question 1c.
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review93/syphilis-infection-screening-2004
July 15, 2004 - Not an RCT
9
Exclude
No health outcomes described
10
Exclude
Not relevant to key question … New Evidence
Key Question … No studies evaluated this question directly.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/8L5g-QzXLDnUofBUE457DN
July 01, 2004 - Summary of New Evidence
Key Question
1. … No studies evaluated this question directly. … care
8 Exclude Not an RCT
9 Exclude No health outcomes described
10 Exclude Not relevant to key question
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/boPWHmzrtxnkkPQAoCNENS
September 18, 2018 - Benefits for Health Outcomes
Key Question 1. … Benefits for Weight Control
Key Question 2. … Harms of Interventions
Key Question 3. … Summary of Evidence, by Key Question and Intervention Type (continued)
Inter-
vention
No. of Studies … Summary of Evidence, by Key Question and Intervention Type (continued)
Inter-
vention
No. of Studies
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/prostate-cancer-screening-adults
December 21, 2023 - Abbreviations: KQ=key question; MRI=magnetic resonance imaging; PSA=prostate specific antigen.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/depression-in-children-and-adolescents-screening
February 08, 2016 - Appendix Table 1 and the full evidence report include all of the search strategies used for each key question … studies that at least 1 reviewer indicated as potentially meeting our prespecified criteria for each key question … We rated the overall body of evidence for each key question using the system developed by the USPSTF. … found no trials meeting the inclusion and quality criteria for this review that examined the overall question … Intervention, by Key
Question
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/XAaYbGVD_xRoMfQ-huJkJq
December 10, 2019 - Benefits of Screening
Key Question 1. … Benefits of Rescreening
Key Question 2. … Harms of Screening
Key Question 3. … Harms of Early Treatment for Small AAAs
Key Question 5. … A summary of the evidence by key question is provided in
Table 5.
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary19/colorectal-cancer-screening
May 18, 2021 - Benefits of Screening
Key Question 1. … Accuracy of Screening
Key Question 2. … Harms of Screening
Key Question 3. … Key Question 1: Overall Summary of Impact of Screening vs No Screening on Colorectal Cancer Incidence … Key Question 2: Summary of Test Accuracy Results From Studies With Colonoscopy Follow-Up for Stool and
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/tobacco-use-in-adults-and-pregnant-women-counseling-and-interventions
January 19, 2021 - Health Benefits of Interventions
Key Question 1. … among men at high risk for cardiorespiratory disease. 96
Cessation Benefits of Interventions
Key Question … Health Benefits of Interventions
Key Question 1. … Cessation Benefits of Interventions
Key Question 2. … smokeless tobacco users Varenicline
February 2014
3
✓
✓
Abbreviations: KQ, key question