October 01, 2010 - We assessed the overall strength of the body of evi-
dence for each key question (good, fair, or poor … (Key Question 1)
We identified no RCTs of screening for bladder can-
cer. … KQ � key question; RCT � randomized, controlled trial.
* These studies did not meet formal inclusion … DISCUSSION
Table 2 summarizes the results of this evidence syn-
thesis, by key question. … KQ � key question.
March 01, 2009 - Data Synthesis
We synthesized the studies qualitatively and organized
them by key question. … Key Question 1
Does aspirin use in men and women without known
cardiovascular disease decrease coronary … Key Question 2
Does aspirin use in women and men increase gastrointes-
tinal bleeding or hemorrhagic … Four studies
provided information on the harms of aspirin for this key
question. … The meta-analysis of
RCTs discussed for the key question on benefits (8) re-
ported adverse events with
April 01, 2003 - Four key questions guided our literature searches and synthesis of the evidence:
Key Question No. … Key Question No 2: How can we most effectively identify patients with hypertension for whom treatment … Key Question No. 4: What are the adverse effects of screening and treatment for hypertension? … Key Question 3: How Effective Is Treatment of Hypertension (Pharmacological or Nonpharmacological) in … Key Question 4: What are the Adverse Effects of Screening and Treatment for Hypertension?
January 01, 2010 - Four key questions guided our literature searches
and synthesis of the evidence:
• Key Question No. … • Key Question No. 2: How can we most
effectively identify patients with hypertension
for whom treatment … • Key Question No. 4: What are the adverse
effects of screening and treatment for
hypertension? … Results
Key Question 1: Does Screening
for Hypertension Reduce
Cardiovascular Disease and
Mortality? … Key Question 4: What Are the
Adverse Effects of Screening
and Treatment for Hypertension?
November 15, 2009 - At the top of the figure is a circle with a "1" in it for key question 1. … ‡ Some articles are included for more than 1 key question. … Harms associated with mammography screening (key question 2a)
Several systematic reviews and primary … Clinical breast examination screening benefits (key question 1b)
1 (2 in progress)
RCT
The … Breast self-examination screening harms (key question 2c)
3
2 RCTs and 1 observational study
September 23, 2014 - ; and met additional prespecified inclusion criteria for each key question 13 . … one new trial evaluated the effectiveness of screening for chlamydia in nonpregnant women 19 (key question … The only new study addressing the effectiveness of different screening strategies (key question 2) was … a positive test result, included symptomatic participants, and lacked comparison groups 39–42 (key question … Both scatterplots are further described in the evidence section for Key Question 3.
September 23, 2014 - ; and met additional prespecified inclusion criteria for each key question 13 . … one new trial evaluated the effectiveness of screening for chlamydia in nonpregnant women 19 (key question … The only new study addressing the effectiveness of different screening strategies (key question 2) was … a positive test result, included symptomatic participants, and lacked comparison groups 39–42 (key question … Both scatterplots are further described in the evidence section for Key Question 3.
October 15, 2008 - Interventions to Reduce STIs in Adults and Adolescents Based on Randomized, Controlled Trials (Key Question … Their results, however, were not reported separately for this subgroup. 16
Key Question 2
Does … Key Question 3
Does primary care behavioral counseling to prevent STI result in benefits other than … Second, trials for key question 2 using self-reported behavioral outcomes should be interpreted with … Key question 4: adverse effects
Adults
11 RCTs
No significant limitations or
January 01, 2010 - Key question 5 (Do sexual behavior changes lead to a reduced incidence of STI, or related morbidity and … RESULTS
Key Question 1
Is there direct evidence that primary care counseling to
reduce risky sexual … Key Question 3
Does primary care behavioral counseling to prevent STIs
result in benefits other than … Key Question 4
Are there harms from primary care behavioral counseling
to prevent STI? … Key question 3:
other positive outcomes
Adults
4 RCTs Limited number of trials
reporting additional
July 14, 2016 - Abbreviations: ECG = electrocardiography; KQ = key question … In general, the figure illustrates the overarching question of whether screening for atrial fibrillation
February 15, 2008 - This arrow has a circle above it labeled "KQ2" for "key question #2. … Note: KQ = key question.
Return to Table of Contents
Figure 2. … ‡ We included 7 additional studies for key question 2 and 2 for key question 3 from the 2001 report … ‡ We included 7 additional studies for key question 2 and 2 for key question 3 from the 2001 report … Specific Searches per Key Question *
Key Question
Search Strategy
1—Screening
August 15, 2012 - Perceived hearing loss can be assessed by asking a single question (for example, “Do you have difficulty … rub, and watch tick tests (bearing in mind that many modern watches no longer audibly tick); single-question … Simple screening methods, such as the whispered voice test and single-question screening, seem to be … LRs) among the screening tests at greater than 25 or 30 dB were in the range of 3.0 to 5.1 for single-question … Negative LRs ranged from 0.03 to 0.52 for whispered voice test, single-question screening, and HHIE-S
March 20, 2018 - Effects of Interventions on Health Outcomes
Key Question 1. … Harms of Interventions
Key Question 3. … Harms of Skin Self-Examination
Key Question 5. What are the harms of skin self-examination? … Summary of Evidence, by Key Question: Children and Adolescent Trialsa … Summary of Evidence, by Key Question: Adult and Young Adult Trialsa
July 10, 2018 - Accuracy of Screening
Key Question 2. … Harms of Screening
Key Question 3. What are the harms of screening for PAD with
the ABI? … Benefits of Treatment
Key Question 4. … Harms of Treatment
Key Question 5. … Summary of Evidence by Key Question
Total No. of
Studies and
Design, No. of
Participants
Randomized