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www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-appendix-iv-roles-and-responsibilities-uspstf-members-serving-topic-lead
July 01, 2017 - Assessing the evidence on each key question as convincing, adequate, or inadequate.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/kGvn_HBPEEdfu2rs38VN8_
March 11, 2025 - Accuracy of Screening Instruments
Key Question 2. … Citations identified through other sources
(eg, reference lists, peer reviewers)
KQ indicates key question … the screener being administered independently from the refer-
ence standard.19
Assessment Harms
Key Question … Intervention Benefits
Key Question 4. … Intervention Harms
Key Question 5.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/obesity-in-children-and-adolescents-screening
June 30, 2022 - Abbreviations: BMI=body mass index; KQ=key question … Food and Drug Administration; KQ=key question; MET=metabolic equivalent of task; USPSTF=U.S.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/gestational-diabetes-screening
June 06, 2019 - Abbreviations: GDM=gestational diabetes mellitus; IGT=impaired glucose tolerance; KQ=key question; T2DM … Pregnancy Outcome Study; IADPSG=International Association of Diabetes and Pregnancy Study Group; KQ=key question
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/6desD2XJCQKF8ZDPMS-NU_
July 01, 2005 - Results
Key Question 1. … included in previous systematic evidence reviews.39-43
Key Question 2a. … Key Question 2b. … Key Question 2c. … Key Question 5.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obesity-in-children-and-adolescents-screening-june-2017
June 20, 2017 - Effects of Interventions on Health Outcomes
Key Question 3. … Efficacy of Interventions by Patient Subgroups
Key Question 4c. … Harms of Interventions
Key Question 5. … The following number of articles were included for Key Question 1 (n=0), Key Question 2 (n=0), Key Question … 3 (n=26), Key Question 4 (n=98), and Key Question 5 (n=33).
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/latent-tuberculosis-infection-screening
May 02, 2023 - Benefits of Screening
Key Question 1. … Screening Accuracy
Key Question 2a. … Harms of Screening
Key Question 4a. … Key Question 4b. Do these harms differ by screening method or strategy?
Key Question 4c. … Harms of Treatment
Key Question 5.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/dvDjnZzW9PDxzKBauB4QxA
August 21, 2018 - Results
Effectiveness of Screening
Key Question 1. … Key Question 1a. … Key Question 1b. … Harms of hrHPV Screening
Key Question 2. … Key Question 2a.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/falls-prevention-community-dwelling-older-adults-interventions
July 21, 2022 - Contextual Question
Contextual
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/syphilis-infection-nonpregnant-adults-adolescents-screening
January 28, 2021 - Abbreviations : AUC = area under the curve; c = concordance; HIV = human immunodeficiency virus; KQ = key question
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/bF5BNLvASN5r9EnP3VTJPN
December 01, 2010 - 1),
intermediate cardiovascular disease–related outcomes (key
question 2), behavioral outcomes (key … question 3), and
harms of the counseling interventions (key question 4). … Data Sources and Searches
To identify literature published for each key question
since the previous … Key Question 4: Harms
Adverse effects were rarely noted in physical activity
counseling trials. … CVD � cardiovascular disease; KQ � key question.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/sZN5HHS8w5Sar6bBPabsaB
June 01, 2008 - RESULTS
Key Question 1
Is there direct evidence that systematic screening for type 2
diabetes, impaired … Key Question 2
Does beginning treatment of type 2 diabetes early as a
result of screening provide an … We identified no studies that directly explored this
question by comparing treatment effects between … Key question 2: diabetes treatment
8 studies RCTs with diabetes vs. … Key question 5: adverse effects of treatment
24 studies Systematic reviews (111–113,
115–124, 126–136
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/carotid-artery-stenosis-screening
November 14, 2019 - stenting; CAS: carotid artery stenosis; CEA: carotid endarterectomy; CVD: cardiovascular disease; KQ: key question
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/myqvgr-dsW7k3eQbwj4aR4
February 01, 2013 - Articles excluded for key
question 1 (n = 105)
Relevance: 1
Location/setting: 26
Inadequate control … 1
(n = 0)
Articles excluded for key
question 2 (n = 82)
Relevance: 1
Location/setting: 26
Inadequate … 2
(n = 23 [18 trials])
Articles excluded for key
question 3 (n = 87)
Relevance: 8
Location/setting … 3
(n = 24 [19 trials])
Articles reviewed for key
question 1
(n = 105)
Articles reviewed for key
question … 2
(n = 105)
Articles reviewed for key
question 3
(n = 111)
Records identified through
database searching
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary25/folic-acid-to-prevent-neural-tube-defects-preventive-medication-2009
May 15, 2009 - We organized synthesized evidence by key question. … Key Question 1
Does folic acid supplementation in women of childbearing age reduce the risk for a pregnancy … Our literature search to answer this question returned 4 articles that met the inclusion criteria, were … Key Question 2
Does folic acid supplementation in women of childbearing age increase the risk for any … Note: KQ = key question.
Text Description .
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/human-immunodeficiency-virus-hiv-infection-pregnant-nonpregnant-adults
February 22, 2024 - EFV = efavirenz; EVG = elvitegravir; EVG/c = elvitegravir/cobicistat; FTC = emtricitabine; KQ = Key Question … ritonavir; DTG = dolutegravir; FTC = emtricitabine; INSTI = integrase strand transfer inhibitor; KQ = Key Question
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/y6xRBv7uSZY5bGCx7y48x7
May 01, 2009 - We organized synthesized evidence by key question. … Key Question 1
Does folic acid supplementation in women of childbear-
ing age reduce the risk for a … Our literature search to answer this question returned
4 articles that met the inclusion criteria, were … Key Question 2
Does folic acid supplementation in women of childbear-
ing age increase the risk for … Studies Excluded After Abstraction and Quality Rating for Key Question 2 (Harms)
Study, Year (Reference
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/hypertension-in-adults-screening
April 27, 2021 - Benefits of Screening
Key Question 1. … Test Accuracy
Key Question 2. … Key Question 2a. What screening protocol characteristics define the best test accuracy? … Key Question 3. … Key Question 3a. What confirmation protocol characteristics define the best test accuracy?
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/breast-cancer-medication-use-reduce-risk
December 28, 2023 - according to design-specific criteria
Abbreviations: DCIS=ductal carcinoma in situ; KQ=key question
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/svy-CsBNaoaeb7wRGFvLdW
January 26, 2016 - Benefits of Screening
Key Question 1. … Key Question 1a. … Harms of Screening
Key Question 3. … Harms of Treatment
Key Question 5. … Key Question 5b.