-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer-update_executive.pdf
December 01, 2014 - Key Question 2. … Key Question 3. … Key Question 4. … In this update, we did not identify any new evidence
that specifically addressed Key Question 3. … In this update, we did not identify any new evidence
that specifically addressed Key Question 4.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/palliative-care-tools_research-protocol.pdf
April 14, 2016 - We will catalog included tools and compile
information on their characteristics (Guiding Question 1) … , catalog the context in which
they are used (Guiding Question 2), and describe the current state of … research for tools in
each area (Guiding Question 3). … We will provide a summation of relevant issues and gaps
to answer Guiding Question 4. … evaluate a patient’s symptoms, such as pain; the quality of care, such as asking a
patient a follow-up question
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy_surveillance.pdf
July 01, 2012 - 2011
Surveillance Report 2nd Assessment: July, 2012
Key Findings, 1st Assessment:
• For Key Question … • For Key Question 2, there may now be enough studies to
conduct a meta-regression on the effect … • For Key Question 3, experts felt the conclusion on number
of surgical procedures required after … SCEPC Conclusions of validity of CER
conclusion(s)
Prior
Assessment
Cumulative
Assessment
Key Question … Do Not Know
Key Question 1: In women with a palpable or nonpalpable breast abnormality, what is the
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_4-user-guide-to-ocer_130129.pdf
January 01, 2010 - These examples show that methods for measuring
exposure, even for addressing the same clinical
question … strengths and limitations of different options that
are available given the nature of the research
question … Conceptual Considerations for
Exposure Measurement
Linking Exposure Measurement to
Study Question … investigators have selected
different exposure time windows even when
examining the same clinical question … this choice
should be related back to the conceptual framework
and biological plausibility of the question
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0583-131115.pdf
March 13, 2013 - Sensitivity of monitoring for low dose tacrolimus [not a comparative effectiveness
question; should … monitoring time points.
§ In addition, tacrolimus dose minimization strategies have raised the question
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_disposition-comments.pdf
March 10, 2010 - Unclear question, which “case” is the reviewer asking about? … It is too simplistic and not
considering the research question, clinical and methodological diversity … As stated above, synthesis of evidence is a dictate of the question
posed for a systematic review. … -- therefore this is a very broad question with
much explected heterogeneity and it is reasonable to … assume the effect
measure to have a distribution, if the research question itself is
meaningful.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/presentations-future_research.pdf
April 01, 2012 - However, many
reviews find only low or moderate strength of evidence to address a given Key Question … The question of the ―desirable‖ level of detail in laying out future research needs is related to
larger … The advantages and disadvantages of a study design
might change depending on the study question or … The final key question of each NIH
Consensus Development Conference relates to research needs, based … in a separate table for each question.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-postpartum-screening_research-protocol.pdf
May 01, 2013 - A third question should be considered if the woman answers “yes” to
either of the initial questions: … Addressing the question of which treatments are most
effective would require a different design. … The revised KQs are as follows:
Question 1
This question has two parts:
a. … Question 2
This question has two parts:
a. … Question 4
What are the comparative benefits of screening for postpartum depression when compared
-
effectivehealthcare.ahrq.gov/sites/default/files/calcineurin-inhibitor_disposition-comments.pdf
March 15, 2016 - C0 vs C2 for Key Question 2). … The key
outcomes to each question are well developed, clear
and concise. … 2", they
instead found an abbreviation for the question and put
that in the title. … C2,
Key Question 2) was limited
in both quantity and quality. … The focus of our analysis for
Key Question 3 was on the
use of CNIs.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mrsa-screening-2010_research-protocol.pdf
January 01, 2010 - Question 1
Among ambulatory or hospitalized patients, what is the comparative effectiveness of … Question 2
Among ambulatory or hospitalized patients, what is the comparative effectiveness of … Question 3
Among ambulatory or hospitalized patients, what is the comparative effectiveness of … Question 4
Among ambulatory or hospitalized patients, what is the comparative effectiveness of … Question 6
Source: www.effectivehealthcare.ahrq.gov
Published Online: October 24, 2011
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharm-treatment-chronic-pain-protocol.pdf
December 11, 2018 - 1: Nonradicular chronic low back pain
o Key Question 2: Chronic neck pain without radiculopathy or … myelopathy
o Key Question 3: Pain related to primary or secondary osteoarthritis
o Key Question 4 … : Fibromyalgia
o Key Question 5: Primary chronic tension headache (defined as 15 or more
headache … days per month for at least 3 months)
o Key Question 6: Patients with any of the five chronic pain … Analytic framework for noninvasive nonpharmacologic treatment for chronic
pain
KQ=Key Question
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
March 01, 2012 - utilization, which is a part of Key
Question 1. … This is a rhetorical question. … Peer Reviewer #4
Results Therefore, Question 1 is unanswerable. … See response to Question 3. … Key Question #3 is answered in the abstract.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ankyloglossia_research-protocol.pdf
June 30, 2014 - Key Question 1 is focused on breastfeeding
outcomes in infants treated for ankyloglossia. … Key Question 3
addresses social concerns, and Key Question 4 addresses ankyloglossia with concomitant … Key Question 1 (KQ1)
What are the benefits and harms of various treatments in breastfeeding newborns … Key Question 2a + b (KQ2)
KQ 2a What are the benefits and harms of various treatments* in newborns, … We will prepare summary tables to address each Key Question.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia-2011_research-protocol.pdf
January 01, 2011 - Four KQs will be addressed in our systematic review:
Question 1 (Overarching Question)
What … If direct evidence is not sufficient to
address this question, the overarching question can be indirectly … Question 3
In stages 3–5 nondialysis and dialysis CKD patients with iron-deficiency anemia, what … Question 4
What factors affect the test performance and clinical utility of newer markers of iron … Grading the Evidence for Each Key Question
We will follow the AHRQ Methods Guide
32
to evaluate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-adults-prisons_research-protocol.pdf
September 13, 2012 - Question 2 was further modified to more clearly indicate the types of community-oriented
interventions … Key Question 1
What is the comparative effectiveness of interventions applied within a jail, prison, … Any articles possibly meeting the inclusion criteria for at least one key question will be
obtained … 1 and a
“yes” on question 2 below and have at least 50 percent of the other items on the
checklist … Assessing the Applicability of the Evidence for Each Key Question
Applicability will be assessed by
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/public-reporting-quality-improvement_research-protocol.pdf
August 17, 2011 - Key Questions for Objective 1
Question 1
Does public reporting result in improvements in the … Question 2
What harms result from public reporting?
B. … Key Questions for Objective 2
Question 3
Does public reporting lead to change in health care … Question 4
Does public reporting lead to change in the behavior of patients, their representatives … Question 6
What contextual factors (population characteristics, decision type, and environmental)
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
September 29, 2014 - criteria, we broadened criteria to
discuss evidence on uncontrolled
studies for this Key Question … At best the results
demonstrate the inadequacy of the evidence to answer the key question. … Suggest dividing into one
table for each key question. … Same question for
opioids and fractures (I assume
mediated through falls)? … Suggestion question B is
addressed by the Key Questions in
the report.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_executive.pdf
August 01, 2013 - Summary of findings for Key Question 2: Pharmacological or
food supplement interventions
Outcome # … Summary of findings for Key Question 2: Pharmacological or
food supplement interventions (continued … Summary of findings for Key Question 2: Medical interventions
Outcome
# of
Articles
Overall Strength … Key Question 2
Population
• Include a broader spectrum of adult patients with
respect to age, sex … Key Question 3
• Develop studies to evaluate the natural history and
prognostic factors in persons
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay-future_research.pdf
September 01, 2012 - ES-2
• Key Question 1: Does adding the SFLC assay and the kappa/lambda ratio to traditional
testing … • Key Question 3: In patients with an existing diagnosis of PCD (MM, nonsecretory MM,
or AL amyloidosis … • Key Question 5: In patients with an existing diagnosis of PCD (MM, nonsecretory MM,
or AL amyloidosis … Key Question 4 of the CER was, “In
patients with an existing diagnosis of PCD (MM, nonsecretory MM, … We therefore rated the strength of evidence as insufficient for this question.
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/ems-911-workforce-protocol.pdf
January 01, 2015 - For Guiding Question 1, we will define occupationally-acquired exposures to infectious
diseases as contact … prevention and control in EMS/911 workforce
(IPC = infection prevention and control; KQ = key question … information
about the epidemiologic characteristics of the infectious disease exposures
(Guiding Question … manufacturers, researchers,
payers, or other perspectives, depending on the technology/intervention in question