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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
    August 01, 2012 - B) for this assessment.5-21 New pertinent studies were identified for Key Question 1 (effectiveness … , health outcomes), Key Question 2 (effectiveness, intermediate outcomes), Key Question 3 (adverse events … However, the expert mentioned that the most critical question— the risk of switching from innovator … This expert did not agree with the prioritization of adverse events in the key question, indicating … Evidence Tables Evidence Table Key Question 1.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
    August 01, 2012 - B) for this assessment.5-21 New pertinent studies were identified for Key Question 1 (effectiveness … , health outcomes), Key Question 2 (effectiveness, intermediate outcomes), Key Question 3 (adverse events … However, the expert mentioned that the most critical question— the risk of switching from innovator … This expert did not agree with the prioritization of adverse events in the key question, indicating … Evidence Tables Evidence Table Key Question 1.
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-adolescents_research-protocol.pdf
    March 29, 2011 - Question 5 Among adolescents and young adults with ASDs, what harms are associated with available … Question 6 What are the effects of interventions on family outcomes? … Grading the Evidence for Each Key Question Assessing the strength of evidence. … Question 4 Among adolescents and young adults with ASDs, what harms are associated with available … Question 6 What are the effects on family adaptation and family outcomes of interventions directed
  4. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
    February 01, 2012 - Key Question 1: Disorder-specific and nonspecific symptoms. … Summary of the strength of evidence for symptoms (Key Question 1) Outcome Comparison (# studies) SOE … Summary of the strength of evidence for symptoms (Key Question 1) (continued) Outcome Comparison (# … Key Question 3: Short- and long-term outcomes. … Key Question 4: Subpopulations.
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-screening_research-protocol.pdf
    October 20, 2011 - Question 2 This Key Question has two parts: a. … Question 3 What are the harms associated with screening for HCV infection, including adverse effects … Question 4 Source: www.effectivehealthcare.ahrq.gov Published Online: October 20, 2011 … Question 5 What are the harms associated with the workup for guiding treatment decisions? … Question 6 This KQ has three parts: a.
  6. effectivehealthcare.ahrq.gov/products/kidney-disease-medicine/research-protocol
    July 28, 2010 - KEY QUESTION 3: Among adults with CKD stages 1-3, whether detected by systematic screening or as part … Comparators: Placebo, usual care, or active control Outcomes for each question Benefits … Evidence tables will be organized by key question. … Data Synthesis We will present results in evidence and summary tables organized by key question. … Grading the Evidence for Each Key Question The strength of the evidence for each key question will
  7. effectivehealthcare.ahrq.gov/products/stem-cell-children/research-protocol
    August 05, 2010 - Key Question 1. … Key Question 2. … Key Question 3. … Key Question 4. … Key Question 5.
  8. effectivehealthcare.ahrq.gov/products/alcohol-misuse/research-protocol
    July 22, 2011 - Question (SASQ). … Question 4 How do behavioral counseling interventions, with or without referral, compare with usual … Question 7 To what extent do health care–system influences promote or hinder effective screening and … Abbreviations: KQ = key question; PICOTS = populations, interventions, comparators, outcomes, timing, … Contextual Question For this report, we will address the question of whether there are effective treatments
  9. effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-e-1.xlsx
    January 01, 2009 - Study characteristics of RCTs addressing Key Questions 1 and 2 Key Question Author, Year Country Quality … Outpatient Intervention Inpatient Intervention Fetal Monitoring Protocol Funding Source Comments Key Question … Key Question 2 Henry, 2013 Australia Fair Age, mean (yr): 32.82 ≤19: NR ≥35: NR BMI, mean (kg/m2): … Key Question 2 Sciscione, 2001 USA Fair Age, mean (yr): 29.17 ≤19: NR ≥35: NR BMI, mean (kg/m2): NR … Study characteristics of cohort studies addressing Key Question 3 Key Question Author, Year Country
  10. effectivehealthcare.ahrq.gov/products/preterm-birth-terbutaline-pump/research-protocol
    August 05, 2010 - women with RPTL and women without RPTL Question 3: increase the maternal harms of pulmonary edema, … Question 4: increase the neonatal harms of hypoglycemia, hypocalcemia, and ileus? … with decreased cervical length and/or women with a positive fetal fibronectin test for Key Question … Key question 5 This question aims to further explore reasons for heterogeneity in outcomes by examining … This, we think, is a question that is unnecessary and not applicable for our primary studies.
  11. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_executive.pdf
    October 01, 2007 - Key Question 2. … Key Question 1b. … Key Question 2a. … Key Question 2c. … Key Question 2d.
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/traumatic-brain-injury-rehabilitation-future_research.pdf
    January 01, 2013 - Analytic framework Abbreviations: KQ = Key Question; TBI = traumatic brain injury The literature … This question was addressed by the CER KQs. … If a stakeholder assigned a question the number one priority, that question received three points; … This question was addressed by the CER KQs. … Research Design Considerations This question was explored in the CER.
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mrsa-screening-2010_disposition-comments.pdf
    January 01, 2010 - In the Results chapter, each Key Question has a strength of evidence section that has been revised … In the Results chapter, each Key Question has a strength of evidence section that has been revised … ES-10 (pdf p. 20), line 43: “y Question 1:” should be “Key Question 1:” We have corrected this typo … How is this question different from what was described for Questions 3a/b/c? … 3B but not Key Question 3A?
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rotator-cuff-tears-future_research.pdf
    February 01, 2013 - 1 Exercise Complications / harms Complications / harms Key Question 2 Key Question 3 Key … Question 4 Key Question 5 Key Question 5 Patient / clinical factors POPULATION INTERVENTION … The most important question in rotator cuff treatment is “what to do and for whom?” … as the important overarching question. … Weighted scores totaled the number of stars stakeholders assigned to an individual issue or question
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
    March 01, 2018 - Question 2. … Question 3. … Question 2. … Question 4. … Question 2.
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/wireless-motility-capsule-future_research.pdf
    May 01, 2013 - Insufficient KQ = Key Question; ROM = radiopaque markers; WMC = wireless motility capsule Overall … The highest ranked question reflected the uncertainty in the role of the WMC in outcomes for patients … The other top ranked question asked whether these same patients with suspected gastroparesis would have … Summary of research needs (top tier) Gap Question Population Intervention Comparator Outcomes Timinga … We also offered them space to comment on any specific study designs relevant to a particular question
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
    February 10, 2016 - Analytic  framework  for  Key  Question  1     *Includes  breathing  difficulties  during  sleep   … Analytic  framework  for  Key  Question  1b     *Includes  breathing  difficulties  during  sleep   … Analytic  framework  for  Key  Question  1c     *Includes  breathing  difficulties  during  sleep   … Analytic  framework  for  Key  Question  1d         *Includes  breathing  difficulties  during   … Abbreviations:  KQ  =  Key  Question;;  OSDB  =  Obstructive  Sleep-­Disordered  Breathing   Harms  
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-stenting-future_research.pdf
    January 01, 2014 - Key Question 2. … 2 Key Question 3. … Key Question 4. … Key Question 5. … Each final FRN topic was assessed as to the context of the research question.
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/children-special-needs-transition_disposition-comments.pdf
    June 17, 2014 - We have added a comment in Guiding Question 1 to address this point. … We have expanded the text on registries in Guiding Question 1. … PMID: 15164956) in the report in Guiding Question 1a. … research and not answering a guiding question”. … We have added text under Guiding Question 1b.
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0411_02-10-2011.pdf
    January 01, 2011 - Nominators: 3 health care professional associations Nomination Summary: The nominators question … In addition, they question whether the benefits and harms of these tests vary by the risk of the surgical

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