-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive.pdf
March 01, 2016 - Key Question 1: Acute Gout Treatment
a. … Key Question 2: Dietary and Lifestyle Management
of Gout
a. … Key Question 3: Pharmacologic Management of
Hyperuricemia in Gout Patients
a. … Key Question 4: Treatment Monitoring of Patients with
Gout
a. … Key Question 5.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_surveillance.pdf
May 16, 2013 - Key question #3
Reduction in recurrence rates of AF (PVI vs. C-PVI)
No new evidence. … Experts (Cycle 2): One expert stated that conclusions in the key question # 1 are still valid. … Experts (Cycle 2): One expert stated that conclusions in the key question # 2 are still valid. … Experts (Cycle 2): One expert stated that conclusions in the key question # 3 are still valid. … Experts (Cycle 2): One expert stated that conclusions in the key question # 4 are still valid.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_disposition-comments.pdf
November 20, 2013 - Rev 7 Intro In question #6, this question could have been further divided
whether BNP/NT-proBNP guided … OR is this more a monitoring
question? … We have included the QUADAS question on threshold in
the assessment of Risk of Bias. … The signaling question asks about “inappropriate”
exclusions. … The target population and key elements of each question
are explicitly defined.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-2005_executive.pdf
January 01, 2005 - Summary of Comparative Data on Treatments of GERD
Key Question 1: Quality of
comparisons evidence Summary … Summary of Comparative Data on Treatments of GERD (continued)
Key Question 1: Quality of
comparisons … Key Question 2: Quality of
modifying factors evidence Summary/conclusion/comments
Weak Data largely … Summary of Comparative Data on Treatments of GERD (continued)
Key Question 3: Quality of
adverse events
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_research-protocol.pdf
October 18, 2010 - A question raised by an individual concerned whether the review will examine
outcomes specific to women … with decreased cervical length and/or women
with a positive fetal fibronectin test for Key Question … Key question 5
This question aims to further explore reasons for heterogeneity in outcomes by
examining … This, we think, is a
question that is unnecessary and not applicable for our primary studies. … Justification: This is essentially the same question as another one we ask while
assessing risk of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-213-lower-limb-protheses-evidence-summary.pdf
September 01, 2018 - Key Question 2. … Key Question 3. … Key Question 5. Expectations of Ambulation
We found no study that addressed this key question. … Key Question 6. Patient Satisfaction With Process
Two studies addressed this Key Question. … Note that this
Key Question did not address satisfaction with the LLP
itself.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-surveillance_research-protocol.pdf
May 19, 2011 - —EDITOR]
Question 1
How have the patient population and the natural history of prostate cancer … Differences in geographical access
Question 2
How are active surveillance and other observational … Behavioral indicators
Question 3
What factors affect the offer of, acceptance, and adherence … Decisionmaking tools and aids
Question 4
What are the comparative short- and long-term outcomes … Costs
Question 5
What are the research needs regarding active surveillance (or watchful waiting
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-knee-future_research.pdf
February 01, 2013 - Analytic framework
KQ = Key Question; OA = osteoarthritis; PT = physical therapy … Stakeholders brought up this question as a
research gap. … If a
stakeholder assigned a question the number one priority, that question received four points; … First topical research need: research design considerations
Research Question: Which PT treatments … Stakeholders brought up this question as a
research gap.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pelvic-pain-therapies-future_research.pdf
January 01, 2015 - Key Question 2. … Key Question 3. … Key Question 4. … Key Question 5. … interventions (Key Question 5).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-pci-adjunctive-devices_research-protocol.pdf
July 01, 2010 - The Key Questions
Question 1
In patients with ACS who are undergoing PCI of native vessels, what … Question 2
In patients with ACS who are undergoing PCI of native vessels, how does the rate
and type … Question 3
In patients with ACS who are undergoing PCI of native vessels, which patient
characteristics … Grading the Evidence for Each Key Question
We will use the Grading of Recommendations Assessment, … The evidence pertaining to each
key question will be classified into three broad categories: high, moderate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/study-design-framework_research.pdf
March 01, 2012 - However,
many reviews find only low or insufficient SOE to address a given key question. … the problem, studies
that replicate the same methodological problems are unlikely to resolve the question … If a question cannot be answered because
all existing studies only measured surrogate markers, additional … The advantages and disadvantages of a study design may change depending on the study
question or the … The
urgency with which an answer to the research question is needed may be an additional ethical
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism_research-protocol.pdf
December 09, 2009 - In addition, Key Question 5 specifically addresses the question of
effectiveness of individual components … abstracted from
data presented in the papers
• Sample sizes must be appropriate for the study question … dimensions (i.e., areas of special focus, or the columns) of each evidence table will
vary by key question … Grading the Evidence for Each Key Question
Quality grading. … develop explicit criteria for rating the overall strength of the
collective evidence on each key question
-
effectivehealthcare.ahrq.gov/sites/default/files/therapies-for-autism-spectrum-disorder-2-9-2010.pdf
January 01, 2010 - In addition, Key Question 5 specifically addresses the question of
effectiveness of individual components … abstracted from
data presented in the papers
• Sample sizes must be appropriate for the study question … dimensions (i.e., areas of special focus, or the columns) of each evidence table will
vary by key question … Grading the Evidence for Each Key Question
Quality grading. … develop explicit criteria for rating the overall strength of the
collective evidence on each key question
-
effectivehealthcare.ahrq.gov/sites/default/files/palliative-care-tools-disposition.pdf
May 04, 2017 - When data do not exist specific to a question, it
would have helped a comprehensive response to the … and compiled
tool characteristics by domain
• Guiding Question 2: we described the current
state … Question 3 on the questionnaire for this group delineates on
line 20, page C-1 ". . .what do doctors … They did not have much feedback
regarding this question. … .
28 Peer Reviewer #3 Methods Page C-2 Questions for the Providers--asks in Question 7,
line 57,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/palliative-care-tools-disposition.pdf
May 04, 2017 - When data do not exist specific to a question, it
would have helped a comprehensive response to the … and compiled
tool characteristics by domain
• Guiding Question 2: we described the current
state … Question 3 on the questionnaire for this group delineates on
line 20, page C-1 ". . .what do doctors … They did not have much feedback
regarding this question. … .
28 Peer Reviewer #3 Methods Page C-2 Questions for the Providers--asks in Question 7,
line 57,
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
January 01, 2015 - exclusion of lipid concentrations as an intermediate outcome.4
The proposed key questions are:
Key Question … Key Question 3a: In adults age 18 or older with type 2 diabetes mellitus, what is the comparative
safety … Key Question 3b: In adults age 18 or older with type 2 diabetes mellitus, what is the comparative
safety … Key Question … Priority Medication Comparisons Included for Each Key Question
Main Intervention Comparisons
Source
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_research-protocol.pdf
November 30, 2011 - Question 2
What is the comparative effectiveness of antiviral treatments on intermediate outcomes … Source: www.effectivehealthcare.ahrq.gov
Published Online: November 30, 2011 4
Question 3 … Question 4
Have improvements in intermediate outcomes (SVR, histologic changes) been shown to reduce … To identify articles relevant to each Key Question (KQ), the librarian will search the
Cochrane Database … Grading the Evidence for Each Key Question
We will use the methods outlined in Chapter 10 of the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/undescended-testicle_research-protocol.pdf
September 02, 2011 - 3
Source: www.effectivehealthcare.ahrq.gov
Published Online: September 2, 2011
Key Question … 4
Source: www.effectivehealthcare.ahrq.gov
Published Online: September 2, 2011
Key Question … The development of testicular malignancy
The size, location, and function of the testes
Key Question … Key Question 5
What is the nature and frequency of harms associated with workup or treatment for … Grading the Evidence for Each Key Question
Assess the Strength of Evidence
We will also use
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
November 24, 2014 - The question
arises how good and reproducible is bias scale? … Peer Reviewer
#2
Results The results for key question 3 are unclear. Would Dr. … We agree that the reviewer’s question about how accurate and
reproducible these measures are, which … There is no direct mention of PK/PD in the question at all
(at least on page 7, lines 24-28). … It is disappointing that there is not more
evidence pertaining directly to the PK/PD question.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-disseminating-findings_0.pdf
October 01, 2018 - in systematic review methods, experience in drafting key messages
and general understanding of the question … In these cases
we inserted the question used to assess the item, with the thought that the questions … Other sections of the EtD were not applicable due to the nature of the question addressed in the
selected … Thus, for the criterion of “Benefits and harms” we inserted the relevant
question (“how substantial … Section
Question: Does different contrast media, within and between osmality classes, affect the