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effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
August 01, 2012 - B) for this assessment.5-21 New
pertinent studies were identified for Key Question 1 (effectiveness … , health outcomes), Key
Question 2 (effectiveness, intermediate outcomes), Key Question 3 (adverse events … However, the expert
mentioned that the most critical question— the risk of switching from innovator … This expert did not agree with the prioritization of adverse events in
the key question, indicating … Evidence Tables
Evidence Table Key Question 1.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
August 01, 2012 - B) for this assessment.5-21 New
pertinent studies were identified for Key Question 1 (effectiveness … , health outcomes), Key
Question 2 (effectiveness, intermediate outcomes), Key Question 3 (adverse events … However, the expert
mentioned that the most critical question— the risk of switching from innovator … This expert did not agree with the prioritization of adverse events in
the key question, indicating … Evidence Tables
Evidence Table Key Question 1.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-adolescents_research-protocol.pdf
March 29, 2011 - Question 5
Among adolescents and young adults with ASDs, what harms are associated with available … Question 6
What are the effects of interventions on family outcomes? … Grading the Evidence for Each Key Question
Assessing the strength of evidence. … Question 4
Among adolescents and young adults with ASDs, what harms are associated with available … Question 6
What are the effects on family adaptation and family outcomes of interventions directed
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
February 01, 2012 - Key Question 1: Disorder-specific and nonspecific
symptoms. … Summary of the strength of evidence for symptoms (Key Question 1)
Outcome Comparison (# studies) SOE … Summary of the strength of evidence for symptoms
(Key Question 1) (continued)
Outcome Comparison (# … Key Question 3: Short- and long-term outcomes. … Key Question 4: Subpopulations.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-screening_research-protocol.pdf
October 20, 2011 - Question 2
This Key Question has two parts:
a. … Question 3
What are the harms associated with screening for HCV infection, including adverse effects … Question 4
Source: www.effectivehealthcare.ahrq.gov
Published Online: October 20, 2011 … Question 5
What are the harms associated with the workup for guiding treatment decisions? … Question 6
This KQ has three parts:
a.
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effectivehealthcare.ahrq.gov/products/kidney-disease-medicine/research-protocol
July 28, 2010 - KEY QUESTION 3:
Among adults with CKD stages 1-3, whether detected by systematic screening or as part … Comparators:
Placebo, usual care, or active control
Outcomes for each question
Benefits … Evidence tables will be organized by key question. … Data Synthesis
We will present results in evidence and summary tables organized by key question. … Grading the Evidence for Each Key Question
The strength of the evidence for each key question will
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effectivehealthcare.ahrq.gov/products/stem-cell-children/research-protocol
August 05, 2010 - Key Question 1. … Key Question 2. … Key Question 3. … Key Question 4. … Key Question 5.
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effectivehealthcare.ahrq.gov/products/alcohol-misuse/research-protocol
July 22, 2011 - Question (SASQ). … Question 4
How do behavioral counseling interventions, with or without referral, compare with usual … Question 7
To what extent do health care–system influences promote or hinder effective screening and … Abbreviations: KQ = key question; PICOTS = populations, interventions, comparators, outcomes, timing, … Contextual Question
For this report, we will address the question of whether there are effective treatments
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effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-e-1.xlsx
January 01, 2009 - Study characteristics of RCTs addressing Key Questions 1 and 2
Key Question Author, Year
Country
Quality … Outpatient Intervention Inpatient Intervention Fetal Monitoring Protocol Funding Source Comments
Key Question … Key Question 2 Henry, 2013
Australia
Fair Age, mean (yr): 32.82
≤19: NR
≥35: NR
BMI, mean (kg/m2): … Key Question 2 Sciscione, 2001
USA
Fair Age, mean (yr): 29.17
≤19: NR
≥35: NR
BMI, mean (kg/m2): NR … Study characteristics of cohort studies addressing Key Question 3
Key Question Author, Year
Country
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effectivehealthcare.ahrq.gov/products/preterm-birth-terbutaline-pump/research-protocol
August 05, 2010 - women with RPTL and women without RPTL
Question 3: increase the maternal harms of pulmonary edema, … Question 4: increase the neonatal harms of hypoglycemia, hypocalcemia, and ileus? … with decreased cervical length and/or women with a positive fetal fibronectin test for Key Question … Key question 5
This question aims to further explore reasons for heterogeneity in outcomes by examining … This, we think, is a question that is unnecessary and not applicable for our primary studies.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_executive.pdf
October 01, 2007 - Key Question 2. … Key Question 1b. … Key Question 2a. … Key Question 2c. … Key Question 2d.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/traumatic-brain-injury-rehabilitation-future_research.pdf
January 01, 2013 - Analytic framework
Abbreviations: KQ = Key Question; TBI = traumatic brain injury
The literature … This question was addressed by
the CER KQs. … If a
stakeholder assigned a question the number one priority, that question received three points; … This question was
addressed by the CER KQs. … Research Design Considerations
This question was explored in the CER.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/mrsa-screening-2010_disposition-comments.pdf
January 01, 2010 - In the Results
chapter, each Key Question has a strength of
evidence section that has been revised … In the Results chapter, each
Key Question has a strength of evidence section
that has been revised … ES-10 (pdf p. 20), line 43: “y Question 1:” should be “Key
Question 1:”
We have corrected this typo … How is this question different from what was described for Questions 3a/b/c? … 3B but not Key
Question 3A?
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/rotator-cuff-tears-future_research.pdf
February 01, 2013 - 1
Exercise
Complications / harms
Complications / harms
Key Question 2
Key Question 3
Key … Question 4
Key Question 5
Key Question 5
Patient /
clinical factors
POPULATION INTERVENTION … The most important question in rotator cuff treatment is “what to do and for whom?” … as the important overarching question. … Weighted scores totaled the
number of stars stakeholders assigned to an individual issue or question
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
March 01, 2018 - Question 2. … Question 3. … Question 2. … Question 4. … Question 2.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/wireless-motility-capsule-future_research.pdf
May 01, 2013 - Insufficient
KQ = Key Question; ROM = radiopaque markers; WMC = wireless motility capsule
Overall … The highest ranked question
reflected the uncertainty in the role of the WMC in outcomes for patients … The other top ranked question asked whether these same patients with suspected
gastroparesis would have … Summary of research needs (top tier)
Gap Question Population Intervention Comparator Outcomes Timinga … We also offered them space to comment on any specific study designs relevant to a
particular question
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
February 10, 2016 - Analytic framework for Key Question 1
*Includes breathing difficulties during sleep … Analytic framework for Key Question 1b
*Includes breathing difficulties during sleep … Analytic framework for Key Question 1c
*Includes breathing difficulties during sleep … Analytic framework for Key Question 1d
*Includes breathing difficulties during … Abbreviations: KQ = Key Question;; OSDB = Obstructive Sleep-Disordered Breathing
Harms
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-stenting-future_research.pdf
January 01, 2014 - Key Question 2. … 2
Key Question 3. … Key Question 4. … Key Question 5. … Each final FRN topic was assessed as
to the context of the research question.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/children-special-needs-transition_disposition-comments.pdf
June 17, 2014 - We
have added a comment in Guiding
Question 1 to address this point. … We have
expanded the text on registries in Guiding
Question 1. … PMID: 15164956) in the
report in Guiding Question 1a. … research and not
answering a guiding question”. … We have added text under Guiding
Question 1b.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0411_02-10-2011.pdf
January 01, 2011 - Nominators: 3 health care professional associations
Nomination
Summary:
The nominators question … In addition, they question whether the benefits and harms of these
tests vary by the risk of the surgical