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effectivehealthcare.ahrq.gov/sites/default/files/vte-protocol-8-4-10.pdf
February 01, 2008 - The Key Questions
Key Questions
Question 1: In patients undergoing major orthopedic surgery (hip … Question 2: In patients undergoing major orthopedic surgery (hip surgery, hip fracture
surgery, or knee … Question 3: In patients undergoing major orthopedic surgery (hip surgery, hip fracture
surgery, or knee … Question 4: In patients undergoing major orthopedic surgery (total hip or knee
replacement, hip fracture … Question 5: In patients undergoing major orthopedic surgery (total hip or knee
replacement, hip fracture
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/blood-clots-hip-knee-surgery_research-protocol.pdf
February 01, 2008 - The Key Questions
Key Questions
Question 1: In patients undergoing major orthopedic surgery (hip … Question 2: In patients undergoing major orthopedic surgery (hip surgery, hip fracture
surgery, or knee … Question 3: In patients undergoing major orthopedic surgery (hip surgery, hip fracture
surgery, or knee … Question 4: In patients undergoing major orthopedic surgery (total hip or knee
replacement, hip fracture … Question 5: In patients undergoing major orthopedic surgery (total hip or knee
replacement, hip fracture
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_executive.pdf
March 01, 2013 - Key Question 2. … Key Question 3. … Key Question 4. … Key Question 5. … Key Question 6.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_research-protocol.pdf
December 06, 2010 - The Key Questions (KQs)
Question 1: For patients with RA, do drug therapies differ in their ability … Question 2: For patients with RA, do drug therapies differ in their ability to improve
patient-reported … Question 3: For patients with RA, do drug therapies differ in harms, tolerability, patient
adherence … Question 4: What are the comparative benefits and harms of drug therapies for RA in
subgroups of patients … Grading the Evidence for Each Key Question
We will rate the strength of evidence based on the standard
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_technical-brief.pdf
December 01, 2012 - ................... 4
Guiding Question 3. … ...... 4
Guiding Question 4. … Guiding Question 4. … (Research question 1).
• Patients. … (Research question 2).
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-safety-practices-rapid-protocol.pdf
September 09, 2022 - Questions 1-4 and 6-7,
include any study with original
quantitative or qualitative data
• For Question … observational studies
with a comparison group
For Questions 1-4 and 6-7:
• No original data
For Question … Risk of Bias (Quality) Assessment
For studies that address Question 5 about the effectiveness of PSPs … For Question 5 about the effectiveness of PSPs, if any of the PSPs have more than
one study, we will
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-results-search-strategies-developed-with-without-text-mining-tools.pdf
March 01, 2021 - Key Question 2a. … Key Question 3. … Key Question 4. … Yield of Relevant Citations (Sensitivity)
Key Question 2b. … Burden of Excess Citations (NNR)
Key Question 3.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/urinary-incontinence-update_research-protocol.pdf
June 06, 2017 - Based on stakeholder input, the 2012 AHRQ review Key Question 1 on the diagnostic
evaluation of UI was … of the 2012 AHRQ review will be similar to the original review with the
following exceptions: Key Question … Contextual Question (new):
What is the available evidence concerning adult women’s conceptions of what … We will add patient-centered outcomes identified from the contextual
question on how patients define … Addressing the Contextual Question
To address the contextual question, we will follow the guidance of
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-diagnosis-future_research.pdf
February 01, 2012 - Key Question 1a. … Key Question 4. … Key Question 1a. … Key Question 2. … Key Question 4.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability.ppt
January 01, 2009 - Applicability should be judged separately for each important question. … Applicability Judged for Each Question
Applicability Judged for Each Question
Rather than judging the … Clinical trials may provide evidence to answer a question about the applicability of a benefit but exclude … For each specific key question being asked, an applicability evidence table is generated. … Applicability Summary Table Template
Domain Description of Applicability Evidence for a Key Question
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effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability.ppt
January 01, 2009 - Applicability Judged for Each Question
Applicability should be judged separately for each important … question. … Applicability Judged for Each Question
Rather than judging the applicability generally for a project, … applicability should be judged separately for each important question. … For each specific key question being asked, an applicability evidence table is generated.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_surveillance.pdf
July 01, 2012 - 1, 1 of 7 conclusions
for Key Question 2, and 1 of 5 conclusions for Key Question
3 are probably out … Key Question 2. … Up-to-date
Up-to-date
Key Question 4. … Up-to-date
Up-to-date
Key Question 5. … Do Not Know
Key Question 4.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
September 19, 2014 - Key Question 3. Dosing Strategies
a. … Analytic framework
KQ, Key Question. … Key Question 2. … Key Question 3. … Key Question 4.
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effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-apbi-breast-cancer.pdf
August 01, 2022 - Literature identified for each KQ
Question Systematic reviews (11/2017-11/2020) Primary studies (11 … /2017-11/2020)
Question 1: PBI
vs. … WBI
Total: 0
Total: 8
• RCT: 6
• Observational: 2
Clinicaltrials.gov: 0
Question 2: PBI … WBI
Total: 0
Total: 2
• RCT: 2
• Observational: 0
Clinicaltrials.gov: 0
Question 4: PBI … imaging
assessment
Total: 0
Total: 0
Question 5:
cosmesis and
toxicity in PBI vs.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/gestational-diabetes-screening-diagnosis_executive.pdf
October 01, 2012 - Comparisons of interest varied by Key
Question and were as follows: Key Question 1 – any GDM
screening … Key Question 1
Fifty-one studies provided data for Key Question 1, which
examined the diagnostic test … Key Question 3
Thirty-eight studies provided data for Key Question
3, which sought to examine health … Key Question 4
Eleven studies provided data for Key Question 4 to assess
the effects of treatment for … Key Question 5
Five studies (four RCTs and one cohort study) provided
data for Key Question 5 on the
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-treatment-future_research.pdf
February 01, 2012 - Key Question 5a. … Key Question 5b. … Key Question 6. … Key Question 7. … Key Question 6.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/obesity-research-methods_research-protocol.pdf
February 08, 2017 - Key Question 4. … Key Question 5. … Key Question 6. … Key Question 3. … Key Question 4.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-refinement_methods.pdf
January 01, 2013 - A refined topic should address an important health care question or dilemma; consider
the priorities … Criteria that a refined topic should fit
♦ The health care question or dilemma the systematic review … Question 1:
a. Sub-Question 1
b. Sub-Question 1
Question 2:
a. Sub-Question 2
b. … A-9
Part 2: Key Question Posting Document for [Insert Title]
Draft Key Questions
Question 1 … Sub-Question 1
d. Sub-Question 1
Question 2
e. Sub-Question 2
f.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_disposition-comments.pdf
October 25, 2011 - Pages 5&6
1 P16 ln 47 Key question 4 has key question 3 glommed
on to the end.
Thank you. … • This is a variation on the above question. … See the comments in question 5,
below. b. … It was not a Key Question. … See discussion of autoPAP in question 4.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/genetic-testing-developmental-disabilities_disposition-comments.pdf
June 30, 2015 - I don't understand this key question. … We revised the question to clarify standard-of-
care diagnostic strategy. … We decided not to change Key
Question 1 as the reviewer suggested. … That
key question potentially addresses multiple
health outcomes. … Per comparators for Key
Question 1, we revised the question to clarify
standard-of-care diagnostic