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  1. effectivehealthcare.ahrq.gov/products/emt-naloxon/research-protocol
    November 30, 2016 - Key Question 2 For patients with confirmed or suspected opioid overdose in out-of-hospital settings … Key Question 3 For patients with confirmed or suspected opioid overdose in out-of-hospital settings … Key Question 4 For patients with confirmed or suspected opioid overdose in out-of-hospital settings … 4: Include Transport to healthcare facility Comparators Key Question 1 : Injection (intramuscular … of different doses of intranasal, intramuscular, and intravenous naloxone Key Question 2 : Titration
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-brain-injury-surveillance-160902.pdf
    January 30, 2014 - •" Key$Question$2. … •" Key$Question$3. … •" Key$Question$4. … •" Key$Question$5. … •" Key$Question$6.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_disposition-comments.pdf
    September 01, 2011 - It was probably important to examine this question in a systematic way, but perhaps there is a way … Key Question 1b required included populations to have 2 or more treatment failures. … It is not included for Key Question 3 (symptom subtypes). … limited information in the published scientific literature to address this question. … Question text, the question also appeared to incorporate an analysis of potential health economic differences
  4. effectivehealthcare.ahrq.gov/products/depression-postpartum-screening/research
    April 09, 2013 - Postpartum Depression Screening Scale, 4 on different versions of the Beck Depression Inventory, 2 on a "two-question … were in the 80–90 percent range, with higher sensitivity associated with lower specificity; the two-question … Modeling suggests that serial testing with a two-question screen followed by a second more specific instrument
  5. effectivehealthcare.ahrq.gov/products/skin-lesions-evaluation/research-protocol
    August 23, 2010 - recognition of skin cancer as a leading form of second malignancy. 2, 3 Guiding Questions Guiding question … Guiding question 2: What is the current clinical context in which these new non-invasive modalities … Guiding question 3: What published and unpublished studies have reported on the use and safety of these … Data to be abstracted for answering Guiding Question 3 are described in section III.2. … Data Presentation We will generate tables (evidence map) summarizing items relevant to Guiding Question
  6. effectivehealthcare.ahrq.gov/products/asthma-provider-adherence/research
    May 19, 2013 - improve health care providers' adherence to asthma guidelines on: (1) health care process outcomes (Key Question … 1); (2) clinical outcomes (Key Question 2); (3) health care processes that subsequently impact clinical … outcomes (Key Question 3).
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-260-improved-cancer-outcomes-disposition-comments.pdf
    May 22, 2023 - precluded formal meta-analyses; nevertheless, unless I have missed it, the sub-parts to each Key Question … be important to provide further detail about the studies that are relevant to each of the a-d Key Question … For example, at the end of Chapter 5 (Key Question 1), we have added a section to indicate the lack … 1a), across the lifespan (Key Question 1b), with varying degrees of muscle wasting (Key Question 1c … ) and in those with a range of comorbid conditions (Key Question 1d), no eligible studies specifically
  8. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/serum-free-light-chain-analysis-for-the-diagnosis
    June 17, 2009 - 17, 2009 Download Topic Suggestion Disposition [PDF · 157.3 KB] Briefly describe a specific question
  9. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/growth-hormone-rhgh-in-patients-with-cystic-fibrosis-cf
    December 28, 2007 - 28, 2007 Download Topic Suggestion Disposition [PDF · 108.2 KB] Briefly describe a specific question
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/uterine-fibroids_research-protocol.pdf
    March 01, 2016 - Key Question 1. … Key Question 3. … Key Question 4. … 2 and Key Question 4. … Key Question 4.
  11. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/multimodal-pain-management-for-post-hip-surgery
    February 29, 2008 - 29, 2008 Download Topic Suggestion Disposition [PDF · 129.6 KB] Briefly describe a specific question
  12. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/clostridium-difficile
    March 10, 2008 - 10, 2008 Download Topic Suggestion Disposition [PDF · 151.8 KB] Briefly describe a specific question
  13. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/lagb-for-metabolic-conditions
    March 10, 2008 - March 10, 2008 Download Topic Suggestion Disposition [PDF · 147 KB] Briefly describe a specific question
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/skin-lesions-evaluation_research-protocol.pdf
    August 23, 2010 - Guiding Questions Guiding question 1: What are the different non-invasive techniques/modalities that … Guiding question 2: What is the current clinical context in which these new non-invasive modalities … Guiding question 3: What published and unpublished studies have reported on the use and safety of these … Data to be abstracted for answering Guiding Question 3 are described in section III.2. … To answer Guiding Question 4, we will make semi-quantitative projection of the various non-invasive
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-gain-future_research.pdf
    January 01, 2020 - Key Questions of the comparative effectiveness review Number Question KQ1. … We created an intervention matrix of comparisons for each Key Question. … (See research question development section below.) … Based upon their responses to this question, we created a methodologic question for future research. … In round 4, stakeholders assigned a score of 1 to 5 to each question, where 5 means that the question
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ocd-protocol.pdf
    August 15, 2023 - Therefore, a separate sub-question related to the harms of testing was removed. … 4 Study Eligibility Criteria Key Question 1 (Diagnosis of OCD) Key Question 2 (Treatment of OCD) … 1 (Diagnosis of OCD) Key Question 2 (Treatment of OCD) Present and Lifetime version (K- SADS-PL) for … 1 (Diagnosis of OCD) Key Question 2 (Treatment of OCD) Family functioning • OCD Family Functioning … For Key Question 2, we will include studies comparing psychological and pharmacological interventions
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_surveillance.pdf
    January 30, 2013 - Key Question 3: increase the maternal harms of arrhythmia, heart failure, hyperglycemia, hypokalemia … Key Question 5: Can the differences in the outcomes above be partially explained by the differences … The conclusion(s) for each key question are found in the executive summary of the CER report.1 … Key question #1 -6 The conclusions from Key question 1 to 6 are still valid. … Key Question # 1- Key Question # 6 Cumulative cycles: 1 and 2 (1st and 2nd assessments) Signals
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_surveillance.pdf
    January 30, 2013 - Key Question 3: increase the maternal harms of arrhythmia, heart failure, hyperglycemia, hypokalemia … Key Question 5: Can the differences in the outcomes above be partially explained by the differences … The conclusion(s) for each key question are found in the executive summary of the CER report.1 … Key question #1 -6 The conclusions from Key question 1 to 6 are still valid. … Key Question # 1- Key Question # 6 Cumulative cycles: 1 and 2 (1st and 2nd assessments) Signals
  19. effectivehealthcare.ahrq.gov/products/rural-telehealth/protocol
    January 15, 2021 - Key Question 2. … Key Question 2. … Key Question 4. … Key Question 1. … Key Question 3.
  20. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/deficit-hyperactivity-protocol.pdf
    November 01, 2021 - The answer to this question is challenging for most clinicians and requires a detailed and accurate … 1), treatment (Key Question 2), and monitoring (Key Question 3) of ADHD, were refined following input … • Key Question 3: Searches will not be limited by date. … as defined by the reference standard does not fully match the review question. … We will answer each key question with the available evidence.

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