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effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-screening_research-protocol.pdf
October 20, 2011 - Question 2
This Key Question has two parts:
a. … Question 3
What are the harms associated with screening for HCV infection, including adverse effects … Question 4
Source: www.effectivehealthcare.ahrq.gov
Published Online: October 20, 2011 … Question 5
What are the harms associated with the workup for guiding treatment decisions? … Question 6
This KQ has three parts:
a.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
March 01, 2018 - Question 2. … Question 3. … Question 2. … Question 4. … Question 2.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/rotator-cuff-tears-future_research.pdf
February 01, 2013 - 1
Exercise
Complications / harms
Complications / harms
Key Question 2
Key Question 3
Key … Question 4
Key Question 5
Key Question 5
Patient /
clinical factors
POPULATION INTERVENTION … The most important question in rotator cuff treatment is “what to do and for whom?” … as the important overarching question. … Weighted scores totaled the
number of stars stakeholders assigned to an individual issue or question
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effectivehealthcare.ahrq.gov/sites/default/files/cer-236-mental-health-pregnancy-evidence-summary.pdf
April 01, 2021 - For women who are currently or planning to become pregnant, a
critical question is whether the benefits … Key Question (KQ) 1: Benefits of Pharmacologic Treatments Versus No
Treatment or Placebo for Pregnant … For the benefits question
4
(KQ 1), eligible studies had comparator arms of women with … For the harms question (KQ 3), however, we were more inclusive and
included studies with comparator
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/traumatic-brain-injury-rehabilitation-future_research.pdf
January 01, 2013 - Analytic framework
Abbreviations: KQ = Key Question; TBI = traumatic brain injury
The literature … This question was addressed by
the CER KQs. … If a
stakeholder assigned a question the number one priority, that question received three points; … This question was
addressed by the CER KQs. … Research Design Considerations
This question was explored in the CER.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
February 10, 2016 - Analytic framework for Key Question 1
*Includes breathing difficulties during sleep … Analytic framework for Key Question 1b
*Includes breathing difficulties during sleep … Analytic framework for Key Question 1c
*Includes breathing difficulties during sleep … Analytic framework for Key Question 1d
*Includes breathing difficulties during … Abbreviations: KQ = Key Question;; OSDB = Obstructive Sleep-Disordered Breathing
Harms
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/wireless-motility-capsule-future_research.pdf
May 01, 2013 - Insufficient
KQ = Key Question; ROM = radiopaque markers; WMC = wireless motility capsule
Overall … The highest ranked question
reflected the uncertainty in the role of the WMC in outcomes for patients … The other top ranked question asked whether these same patients with suspected
gastroparesis would have … Summary of research needs (top tier)
Gap Question Population Intervention Comparator Outcomes Timinga … We also offered them space to comment on any specific study designs relevant to a
particular question
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-stenting-future_research.pdf
January 01, 2014 - Key Question 2. … 2
Key Question 3. … Key Question 4. … Key Question 5. … Each final FRN topic was assessed as
to the context of the research question.
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effectivehealthcare.ahrq.gov/sites/default/files/hawley-presentation.pdf
May 29, 2025 - experienced discrimination during their
colorectal cancer treatment and then in a separate question … But when we looked at
the in daily life question we’re seeing significant differences between … In
this question, where we asked if wisdom comes from personal experience, not from
learning in … We didn’t have the
exact same question about treatment but they were similar.
16
…
In a study which is still in the field now, we asked this question
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/children-special-needs-transition_disposition-comments.pdf
June 17, 2014 - We
have added a comment in Guiding
Question 1 to address this point. … We have
expanded the text on registries in Guiding
Question 1. … PMID: 15164956) in the
report in Guiding Question 1a. … research and not
answering a guiding question”. … We have added text under Guiding
Question 1b.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
November 01, 2012 - Key Question 2
a. … Key Question 3
a. What are the comparative harms associated with
antiviral treatments?
b. … Search Strategy and Study Selection
To identify articles relevant to each Key Question,
a research … We did not perform meta-analyses for Key
Question 4 because all studies were observational and had … Low
Key Question 3b
Do these harms
differ according to
patient subgroup
characteristics?
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/future05-breastcancer-10-5-2010final.pdf
September 01, 2010 - Because two of these priority topic areas, interventions extending beyond medications
(Question B) … /Researcher)
(Question not asked of Consumer/Policymaker) Q8. … the acceptability and effectiveness of risk reduction treatment (Research
Question C)? … C
30
Framework Question(s)
Priority Research
Area (Question)
Research Needed And Potential … For two of these high-priority topics—intervention (Question B) and influencing factors
(Question C
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effectivehealthcare.ahrq.gov/sites/default/files/delilberative-methods-design-goold-2.pdf
May 29, 2025 - Applies to all materials, not just education/information, e.g., how task is
described, how policy question
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_surveillance.pdf
January 01, 2013 - Key Question 1a. … Do Not Know
Key Question 1. … Do Not Know
Key Question 2. … New Evidence:
Key Question 4. … Key Question 4a.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-immunodeficiency-virus-rapid-response.pdf
May 01, 2025 - Key Question 2: What are the clinical practice guidelines or standards for
dental care for people with … Key Question 2: What are the clinical practice guidelines or standards for
dental care for people with … PRISMA flow diagram
3.2 Key Question 1
Key Question 1: What is the effectiveness of dental services … 3.2.1 Results, Key Question 1, Key Points
8
3.2.1 Key Points
• The body of evidence informing … 3.3 Key Question 2
3.3.1 Key Points
3.3.2 Included Guidelines
4.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
April 01, 2013 - Stakeholders assigned a total of seven “stars” (up to three stars for one question) to
methodological … The recent guideline report from the Canadian Headache Society addressed the question of
how long to … Research Design Considerations
This question might be considered a subquestion to an RCT addressing … This question is relevant for chronic as well as episodic migraine
populations. … This question is relevant for chronic as well as episodic migraine
populations.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief1-care-coordination.pdf
April 01, 2021 - 1
Comparators Usual care or no transitional care intervention See question 1
Outcomes Pain, function … , quality of life, readmission, pain
management (including opioid use), adverse
events
See question … 1
Timing Any See question 1
Setting Hospital to home or hospital to nursing facility See question … Table 2 describes the literature found for each question.
6
Table 2. … Literature identified on transitional care interventions for people with pain by question
Question
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief1-care-coordination.pdf
April 01, 2021 - 1
Comparators Usual care or no transitional care intervention See question 1
Outcomes Pain, function … , quality of life, readmission, pain
management (including opioid use), adverse
events
See question … 1
Timing Any See question 1
Setting Hospital to home or hospital to nursing facility See question … Table 2 describes the literature found for each question.
6
Table 2. … Literature identified on transitional care interventions for people with pain by question
Question
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-disease-medicine_research-protocol.pdf
November 01, 2010 - KEY QUESTION 1:
In asymptomatic adults with or without recognized risk factors for chronic kidney … Systematic reviews
will be included if the research question is considered relevant as outlined in … Evidence tables will be organized by key question. … Data Synthesis
We will present results in evidence and summary tables organized by key question. … Grading the Evidence for Each Key Question
The strength of the evidence for each key question will
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse_research-protocol.pdf
April 28, 2010 - Question (SASQ). … Question 4
a. … Question 5
Source: www.effectivehealthcare.ahrq.gov
Published Online: July 21, 2011
6 … Source: www.effectivehealthcare.ahrq.gov
Published Online: July 21, 2011
7
Question 6
How … Contextual Question
For this report, we will address the question of whether there are effective