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effectivehealthcare.ahrq.gov/products/transparency-neuropathy/research-protocol
September 06, 2016 - For this project we will focus on the following sub-question:
Key Question 2a: What is the safety and … Data synthesis
Description of the identified studies (question 1)
For the first question we will … Description of incomplete or discontinued trials (question 3)
We will create separate tables for those … studies that are incomplete or discontinued to address Question 3: "For studies in ClinicalTrials.gov … These data will be extracted as above to address this question.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
March 01, 2012 - Key Question 2. … Key Question 3. … Key Question 4. … Key Question 5a. … Key Question 5b.
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effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-hospital-length-of-stay.pdf
November 01, 2019 - Collectively they cover many
interventions relevant to question 1. … Literature identified for each Question
Question Systematic reviews (7/2016-8/2019) Primary studies … We found 111 reviews that
addressed Question 1, and 3 that addressed Question 2. … Question 1. … Collectively they cover many interventions relevant to question 1.
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effectivehealthcare.ahrq.gov/sites/default/files/cer-226-labor-dystocia-comments.pdf
May 14, 2020 - We have however
revised the key question to
be consistent with the order
in which these specific … Results Peer Reviewer #1 On page 75, for KQ4, it appears the question is only about EA, yet look
at … The key question provides
an overview of the question
to be addressed in that
section. … of this question to:
“Evaluating differences in outcomes with abnormal labor” or something
to that … with
abnormal labor we have not
modified the specific key
question wording.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0768-141211.pdf
October 23, 2014 - Key Question #1: What is the comparative effectiveness of tonsillectomy in children
with recurrent throat … Outcome(s): Number of throat infections, complications of infection, or complications of
surgery
Key Question … Key Question … In consultation with our clinical reviewer, the scope of this topic from the original
nominator question
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/tethered-spinal-cord-protocol.pdf
July 19, 2023 - 1), prophylactic treatment (Key Question 2), symptomatic treatment (Key
Question 3), and repeat surgery … Following the described input, the final key questions are as follows:
Key Question 1: What is the … Key Question 4: Among individuals who experience retethering after spinal
detethering surgery, what … as defined by the
reference standard does not fully match the review question. … We will stratify key
question 3 (treatment) by symptom type, intensity, and patient age.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
March 01, 2011 - Below we provide additional summary information for
selected comparisons of interest by key question, … Key Question 1: Intermediate Outcomes
Intermediate clinical outcomes were the most
frequently evaluated … Therefore, most
comparisons for this key question had a low strength of
evidence. … Key Question 3: Adverse Events and Side Effects
This Key Question was addressed by 107 studies. … Key Question 4: Differences in Subgroups
Twenty-eight studies applied to Key Question 4.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
October 01, 2014 - Key Question 1. … Key Question 2. … Key Question 3. … Key Question 1. … Key Question 2.
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effectivehealthcare.ahrq.gov/products/type-2-diabetes-medications-update/research-protocol
April 05, 2010 - The Key Questions
Key Question 1: In adults age 18 or older with type 2 diabetes mellitus, what is … Outcomes for each question
The outcomes for Key Question 1 are:
HgbA1c
Weight
Low density lipoprotein … High density lipoprotein
Triglycerides
The outcomes for Key Question 2 are:
All-cause mortality … Analytic Framework
HgbA1c = hemoglobin A1c; KQ = Key Question; NPH = neutral protamine Hagedorn … For Key Question 1, we included only RCTs.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/type-2-diabetes-medications-update_research-protocol.pdf
April 06, 2010 - The Key Questions
Key Question 1: In adults age 18 or older with type 2 diabetes mellitus, what is the … Outcomes for each question
The outcomes for Key Question 1 are:
• HgbA1c
• Weight
• Low density … □ For Key Question 1, we included the following outcomes: HgbA1c, weight, and serum lipid levels ( … □ For Key Question 3, we included the following outcomes: hypoglycemia, liver injury, congestive … □ For Key Question 1, we included only RCTs.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-implicit-bias-protocol.pdf
August 04, 2023 - For Review Question 2,
5
we will focus on identifying relevant measures that are included in … PSPs used and explanations of the rationale presented in the studies we find for Review
Question 5 … For Review Question 8, we will identify publicly available patient safety toolkits developed by
AHRQ … Risk of Bias (Quality) Assessment
For studies that address Review Question 5 about the effectiveness … For Review Question 5 about the effectiveness of HCW implicit bias
training and education PSPs, we
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_research-protocol.pdf
October 01, 2013 - dose/volume and number of doses)
Comparators
Key Question 1 and Key Question 2 (see Table 2)
● … Key Question 3 and Key Question 4 (see Table 3)
● IOCM versus LOCM
● LOCM versus LOCM
● IOCM (by … Setting
● Key Question 1 through Key Question 4
● Inpatient and outpatient populations
Source: www.effectivehealthcare.ahrq.gov … Major prevention interventions and comparisons for Key Question 1 and Key Question 2
(These are the … Major contrast media and comparisons for Key Question 3 and Key Question 4
(These are the important
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-2007_executive.pdf
January 01, 2007 - 3
Key Question 2. … Key Question 3. … Key Question 1. … Key Question 2. … Key Question 3.
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effectivehealthcare.ahrq.gov/sites/default/files/prehospital-airway-management-draft-report.pdf
November 01, 2020 - Key Question 1
a. … Key Question 2
a. … Key Question 3
a. … Studies Total
Key Question 1 2 18 20
Key Question 2 2 17 19
Key Question 3 4 34 38
Key Question … , or ETI (Key Question 4).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prehospital-airway-management-draft-report.pdf
November 01, 2020 - Key Question 1
a. … Key Question 2
a. … Key Question 3
a. … Studies Total
Key Question 1 2 18 20
Key Question 2 2 17 19
Key Question 3 4 34 38
Key Question … , or ETI (Key Question 4).
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-appendix-3.xlsx
June 24, 2022 - Frame the question, which may involve use of a PICOTS framework
Pearson Data Curate real world data … and/or develop the plan for data acquisition sufficient answer the question to meet the evidentiary … The specific clinical question of interest drives the consideration regarding whether an RWE approach … is sufficient and robust enough for the regulatory question at hand. … That is, are the data relevant and fit for purpose for the research question at hand?
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2022-update-app-g1.xlsx
January 01, 2022 - 2.4) (If Y, PY to previous question) were these deviations likely to have affected the outcome? … 2.7) (If N, PN, NI to previous question) Was there potential for a substantial impact (on the result) … 3.3) (If N/PN to previous question) Could missingness in the outcome depend on its true value? … 3.4) (If Y, PY, NI to previous question) Is it likely that missingness in the outcome depended on its … 4.5) (If Y/PY/NI to previous question) Is it likely that assessment of the outcome was influenced by
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effectivehealthcare.ahrq.gov/products/progestogens-preterm-birth/research-protocol
April 15, 2010 - Key Questions:
Question 1
In pregnant women who are at risk for preterm birth (< 37 weeks estimated … Question 6
What is the effect of health systems and provider factors on the use of progestogens for … Outcomes for each Key Question Fetal/neonatal outcomes:
Gestational age at birth, including preterm … The dimensions columns in each evidence table will vary according to Key Question, but the Tables will … Grading the Evidence for Each Key Question
Quality Grading.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-failure-rescue-protocol_0.pdf
July 01, 2023 - For Review Question 2, we will focus on identifying
relevant measures that are included in the Centers … including PSPs used and explanations of the rationale presented in the studies we find for Review
Question … For Review Question 8, we will
identify publicly available patient safety toolkits developed by AHRQ … Risk of Bias (Quality) Assessment
For studies that address Question 5 about the effectiveness of PSPs … For Question 5 about the effectiveness of PSPs, we will record information about the
context of each
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/mass-casualty-events-scarce-resources_executive.pdf
June 01, 2012 - This report addresses the following Key Questions:
Key Question 1. … Key Question 2. … Key Question 3. … Key Question 4. … Our data extraction approach was tailored to each Key
Question.