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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
    November 01, 2017 - Key Question 1: For patients with confirmed or suspected opioid overdose, what are the comparative … Key Question 2: For patients with confirmed or suspected opioid overdose in out-of-hospital settings … Key Question 3: For patients with confirmed or suspected opioid overdose in out-of-hospital settings … Key Question 4: For patients with confirmed or suspected opioid overdose in out-of-hospital settings … Key Question 4.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
    September 23, 2016 - (and include all eligible interventions for the key question), include studies that meet the PICOTS … Assessing Key Question 2 Interventions for Evidence Sufficiency Prior to synthesizing evidence for … intervention categories in Key Question 2, we will determine bodies of evidence that are sufficient … As there are large, high quality systematic reviews of the interventions in Key Question 1 that have … The section on “Assessing Key Question 2 Interventions for Evidence Sufficiency” was added, which
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-failure-rescue-protocol-amendment.pdf
    September 19, 2023 - For Review Question 2, we will focus on identifying relevant measures that are included in the Centers … including PSPs used and explanations of the rationale presented in the studies we find for Review Question … For Review Question 8, we will identify publicly available patient safety toolkits developed by AHRQ … Risk of Bias (Quality) Assessment For studies that address Question 5 about the effectiveness of PSPs … For Question 5 about the effectiveness of PSPs, we will record information about the context of each
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/bladder-cancer-muscle-invasive_executive.pdf
    June 01, 2015 - Key Question 1. … Key Question 2. … Key Question 3. … Key Question 4. … Key Question 1.
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioids-chronic-pain-surveillance-report-1-final.pdf
    April 01, 2022 - Key Question 2: Harms Key Question 2a (Opioids Vs. … Key Question 3: Dosing Strategies Key Question 3b (Long- Vs. … B-1 Key Question 2. … B-1 Key Question 3. … B-2 Key Question 4.
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_executive.pdf
    February 01, 2014 - Key Question 1. … Key Question 2. … Key Question 3. … Key Question 4. … Key Question 5.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia_research.pdf
    January 01, 2013 - question). … Key Question 2. … Key Question 3. … question). … Key Question 2.
  8. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/telehealth-during-COVID-19-amendments.pdf
    April 28, 2022 - Proposed methods by key question. … Key Question 2 The question of benefits and harms of telehealth during COVID-19 will be addressed … Key Question 3 We will address the question of what is considered a “successful” telehealth intervention … Key Question 4 The question of implementation strategies for telehealth during COVID-19 will primarily … Key Question 2: Removed qualitative synthesis, and limit studies to comparative studies only Key question
  9. effectivehealthcare.ahrq.gov/sites/default/files/c-diff-infections-nomination-140925.pdf
    February 19, 2014 - Topic Description Key Questions: Key Question 1: How do different methods for detection of toxigenic … B § Gene detection tests versus immunoassays for toxins A and B § Patient characteristics Key Question … alcohol gel § Disinfection § Sustainability § Risk factors § Multiple component strategies Key Question … treatment § Strain of organism § Patient characteristics § Resistance of other pathogens Key Question
  10. 04-E029-1 Summary (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-surveillance_executive.pdf
    December 01, 2011 - Key Question 3 relates to the factors that influence the offer or acceptance of or adherence to AS. … 5): Key Question 1: Studies of large U.S. … Key Question 3: Three types of studies were included. … Time- trend data for Key Question 1 were graphed over the interval of interest (1980–2010). … We included three types of studies to address this Key Question.
  11. effectivehealthcare.ahrq.gov/products/nephropathy-contrast-induced/research-protocol
    November 12, 2013 - dose/volume and number of doses) Comparators Key Question 1 and Key Question 2 (see Table 2 ) … Key Question 3 and Key Question 4 (see Table 3 ) IOCM versus LOCM LOCM versus LOCM IOCM (by dose … Setting Key Question 1 through Key Question 4 Inpatient and outpatient populations Analytic Framework … Major prevention interventions and comparisons for Key Question 1 and Key Question 2* Comparators … Major contrast media and comparisons for Key Question 3 and Key Question 4* Comparators IOCM
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0765-150129.pdf
    November 03, 2014 - Key Question #1: What is the comparative effectiveness of tympanostomy tubes in children with chronic … hearing levels (HLs); speech and language improvement; health-related quality of life (HRQoL) Key Question … Key Questions from Nominator: Key Question … indications for tympanostomy; patient satisfaction with the change in hearing following surgery Key Question … of TTO duration or recurrence; prevention of other complications; school absenteeism; HRQoL Key Question
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-1-nonopioid-treatments-chronic-pain.pdf
    December 01, 2021 - use of nonopioids in patients with chronic pain and addressed the following key questions (KQ): Key Question … Key Question 1b. … Key Question 1c. … Key Question 2b. … 1: Benefits Neuropathic Pain Fibromyalgia Osteoarthritis Low Back Pain Key Question 2: Harms
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hro-protocol.pdf
    January 01, 2023 - : High Reliability Organization (HRO) as a Patient Safety Practice Review Questions Review Question … For contextual question 4, we will identify publicly available patient safety toolkits developed by … Eligibility Criteria We will search for original studies and systematic reviews on the Review Question … Risk of Bias Assessment For studies that address the Review Question about the effectiveness of PSPs … For the Review Question about the effectiveness of PSPs, we will record information about the context
  15. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_executive.pdf
    September 01, 2009 - Key Question 1. … Key Question 2. … Key Question 3. … Key Question 4. … Key Question 5.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-254-rural-telehealth-executive-summary.pdf
    December 01, 2022 - Key Question 1. … Key Question 2. What is the effectiveness of provider- to-provider telehealth for rural patients? … Key Question 4. … Key Question 3. … Key Question 4.
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_executive.pdf
    September 01, 2014 - Key Question 1. … Key Question 1a. … Key Question 1b. … Key Question 1e. … Key Question 2.
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/routine-antenatal-care.pdf
    January 01, 2020 - 4 Study Eligibility Criteria Key Question 1 Population • Pregnant individuals receiving routine … 2 Population • Same as Key Question 1 Interventions • Antenatal care programs using telemedicine … 1 Setting • Same as Key Question 1 Key Question 3 Population • Pregnant individuals • Postpartum … Analytic Framework Abbreviations: KQ = Key Question, QoL = quality of life. … The population and outcomes of interest will be the same as for Key Question 1.
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antenatal-care.pdf
    January 01, 2020 - 4 Study Eligibility Criteria Key Question 1 Population • Pregnant individuals receiving routine … 2 Population • Same as Key Question 1 Interventions • Antenatal care programs using telemedicine … 1 Setting • Same as Key Question 1 Key Question 3 Population • Pregnant individuals • Postpartum … Analytic Framework Abbreviations: KQ = Key Question, QoL = quality of life. … The population and outcomes of interest will be the same as for Key Question 1.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
    February 01, 2013 - Summary of Evidence There is insufficient evidence to answer this Key Question. … Summary of Evidence There is insufficient evidence to answer this Key Question. … All studies addressing this Key Question evaluated IVUS only. … The summary of evidence for each Key Question is provided in Table C. … addressed Key Question 3.

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