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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb-disposition.pdf
    March 10, 2010 - A statement has been added to the introduction to Key Question 7 as recommended. … We have added text to the discussion section following Key Question 1 regarding the impact of blood … Results Key Question 3: Key points: The authors concluded that there is larger studies are needed. … These statements have been removed from the discussion section of Key Question 1 as recommended. … the initiation of therapies between studies included in Key Question 1 and Key Question 3.
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatigue-sleepiness-protocol.pdf
    July 01, 2023 - For Review Question 2, we will focus on identifying relevant measures that are included in the Centers … including PSPs used and explanations of the rationale presented in the studies we find for Review Question … For Review Question 8, we will identify publicly available patient safety toolkits developed by AHRQ … If no recent high quality systematic review is identified that fully addresses Review Question 5, we … Risk of Bias (Quality) Assessment For studies that address Review Question 5 about the effectiveness
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/malnutrition-hospitalized-adults-protocol.pdf
    October 19, 2020 - Key Question 1. … Key Question 2. … Key Question 3. … Interventions/ Exposures Key Question 1: Positive screening for nutrition risk and/or diagnosis of … Key Question 3: Usual care or another hospital-initiated malnutrition-related intervention.
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0715-140408.pdf
    April 08, 2014 - PICO for Key Question #1 Population(s): Children with infantile hemangiomas Intervention(s): Early … referral Outcome(s): Minimization of functional impairment and/or cosmetic deformity PICO for Key Question … Accuracy of diagnosis, identification of complications or potential complications PICO for Key Question … minimization of cosmetic deformity, enhancement of infantile hemangioma involution, safety PICO for Key Question
  5. effectivehealthcare.ahrq.gov/sites/default/files/topic-refinement.ppt
    March 01, 2010 - identify the importance of key questions To describe the characteristics of a well-constructed key question … Is this key question reflecting uncertainties? No. Aliskerin is approved by the U.S. … A Question That Does Not Reflect Uncertainty This slide provides an example of a key question that can … The first question is, “Does aliskerin reduce blood pressure in hypertensive patients more than other … Step 13: The topic refinement and key question posting document is sent to AHRQ.
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-kidney-disease-anemia-2011_disposition-comments.pdf
    January 01, 2011 - However, these data do not address Key Question 4. … or more of the study eligibility criteria for a particular key question. … Testing needs are different when clinical question is too much versus too little iron. … Testing needs are different when clinical question is too much vs. too little iron. … No study was identified to address this question. No response needed.
  7. effectivehealthcare.ahrq.gov/products/chronic-kidney-disease-anemia-2011/research
    October 12, 2012 - We did not identify any study that provided data directly addressing our overarching question Key Question … We identified 27 studies to answer Key Question 2, which addresses the performance of newer markers of … The synthesis of data for Key Question 2 was complicated by the lack of generally accepted reference … We therefore synthesized these 12 studies for Key Question 2. … For Key Question 3 (impact on intermediate outcomes of newer markers compared with older markers), we
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-3-appendix-h-table-h-1.xlsx
    January 01, 2021 - 2.4) (If Y, PY to previous question) were these deviations likely to have affected the outcome? … 2.7) (If N, PN, NI to previous question) Was there potential for a substantial impact (on the result) … 3.3) (If N/PN to previous question) Could missingness in the outcome depend on its true value? … 3.4) (If Y, PY, NI to previous question) Is it likely that missingness in the outcome depended on its … 4.5) (If Y/PY/NI to previous question) Is it likely that assessment of the outcome was influenced by
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd4-update-appendix-g-table-g-1.xlsx
    January 01, 2022 - 2.4) (If Y, PY to previous question) were these deviations likely to have affected the outcome? … 2.7) (If N, PN, NI to previous question) Was there potential for a substantial impact (on the result) … 3.3) (If N/PN to previous question) Could missingness in the outcome depend on its true value? … 3.4) (If Y, PY, NI to previous question) Is it likely that missingness in the outcome depended on its … 4.5) (If Y/PY/NI to previous question) Is it likely that assessment of the outcome was influenced by
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/deprescribing-protocol.pdf
    July 01, 2023 - For Review Question 2, we will focus on identifying relevant measures that are included in the Centers … including PSPs used and explanations of the rationale presented in the studies we find for Review Question … on the barriers, facilitators, and required resources reported in the studies we find for Review Question … For Review Question 8, we will identify publicly available patient safety toolkits developed by AHRQ … Risk of Bias (Quality) Assessment For studies that address Review Question 5 about the effectiveness
  11. effectivehealthcare.ahrq.gov/products/cervical-ripening/protocol
    January 16, 2020 - Contextual Question: What evidence informs preference for or tolerability of different methods of CR … Population, interventions, comparators, outcomes, timing, and settings (PICOTS) for each key question … PICOTS PICOTS Elements Inclusion Key Question 1: Prostaglandin Inpatient vs. … Outpatient Inclusion Key Question 2: Mechanical Method Inpatient vs Outpatient Inclusion Key Question … In this case we will conduct separate searches to identify cohort studies for that specific question
  12. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd_executive.pdf
    September 01, 2011 - Key Question 3. … Summary, Conclusion, Comments Key Question 1. … Evidence Summary, Conclusion, Comments Key Question 1. … Evidence Summary, Conclusion, Comments Key Question 1. … Evidence Summary, Conclusion, Comments Key Question 1.
  13. effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-outpatient-setting-comments.pdf
    March 22, 2021 - Tables of studies under each Key Question in this section is very helpful for quick looks at such a … The Key Question on fetal surveillance was not specific to outpatient versus inpatient settings. … This question was separate, and focused on identifying evidence on outcomes (benefit and harms) of … (note: the "yes" is in response to a readability question about results/conclusions) Thank you for … For each Key Question and comparison, however, we do include descriptions of the fetal monitoring
  14. effectivehealthcare.ahrq.gov/sites/default/files/module-iii-points-of-engagement-in-the-ehc-program.pdf
    January 05, 2017 - Slide 18 Module III Quiz: Question 1 … Discussing key questions § Illustrating clinical context for a topic Slide 19 Module III Quiz: Question … Slide 20 Module III Quiz: Question 2 2. … Development § Peer/Public Review § Report Translation & Dissemination Slide 21 Module III Quiz: Question … Slide 27 Module III Quiz: Question 5: ANSWER § List three ways in which you could locate and recruit
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-antigen-3-gene_research.pdf
    April 01, 2013 - Study design evaluations for PCA3 research need 1, research question 2.2: Does the addition of PCA3 … 1) or rebiopsy (Key Question 2) men at risk for prostate cancer. … Key Question 3 was as follows. … Conclusions by Key Question and strength of evidence are detailed in Appendix A. … Key Question 3 1.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/monitoring-programs-protocol.pdf
    January 01, 2024 - Healthcare Safer IV: Supply Chain Disruption Monitoring Programs Review Questions Review Question … do not address these aspects. 5 For contextual question 4, we will identify publicly available … Inclusion and Exclusion Criteria for the Review Question Study Parameter Inclusion criteria Exclusion … For contextual question 4, we will identify publicly available patient safety toolkits developed by AHRQ … Inclusion and Exclusion Criteria for the Review Question Abbreviations: ED = emergency department; RCT
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/engaging-caregivers-protocol.pdf
    August 04, 2023 - For Review Question 2, we will focus on identifying relevant measures that are included in the The … For Review Question 8, we will identify publicly available patient safety toolkits developed by AHRQ … Risk of Bias (Quality) Assessment For studies that address Question 5 about the effectiveness of PSPs … For Review Question 5 about the effectiveness of PSPs, we will record information about the context … For Review Question 8, we will identify publicly available patient safety toolkits developed by AHRQ
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ped-mindfulness-key-questions.pdf
    April 05, 2024 - Key Question for Systematic Review of Mindfulness-Based Interventions for Mental Health in Children and … Adolescents 1 Key Question for Systematic Review of Mindfulness-Based Interventions for Mental … Definition of Terms AF Analytic Framework KQ Key Question PICOTS Populations, Intervention
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_executive.pdf
    June 01, 2013 - Key Question 2. … Key Question 3. … PICOTS for the Key Questions PICOTS Key Questions 1 and 2 Key Question 3 Population Key Question 1: … 11 Key Question 2, and 17 were relevant to Key Question 3. … 1 (n=35) Key Question 2 (n=6) Key Question 3 (n=17) Excluded records (n=1,123) • Non-English (n=27
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
    November 01, 2017 - Key Question 1: For patients with confirmed or suspected opioid overdose, what are the comparative … Key Question 2: For patients with confirmed or suspected opioid overdose in out-of-hospital settings … Key Question 3: For patients with confirmed or suspected opioid overdose in out-of-hospital settings … Key Question 4: For patients with confirmed or suspected opioid overdose in out-of-hospital settings … Key Question 4.

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