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  1. effectivehealthcare.ahrq.gov/sites/default/files/tnd-0855-170515.pdf
    April 28, 2017 - The questions for this nomination are: Key Question 1a. … Key Question 1b. … Key Question 2a. … 2 Key Question 2b. … Key Questions and PICOs Key Question 1a.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0855-170515.pdf
    April 28, 2017 - The questions for this nomination are: Key Question 1a. … Key Question 1b. … Key Question 2a. … 2 Key Question 2b. … Key Questions and PICOs Key Question 1a.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-911-workforce-mental-health-protocol-amendment.pdf
    January 22, 2024 - Key Questions and Study Eligibility Criteria Key Questions Key Question 1: What are the incidence, … Key Question 4: What future research is needed to close existing evidence gaps regarding preventing, … 1 Key Question 2 Key Question 3 Population EMS/911 workforce o Field responders (either ground or … 1 Key Question 2 Key Question 3 Outcomes ● Incidence of behavioral health issue or occupational … 1 Key Question 2 Key Question 3 Contextual Factors • Individual-level factors o Demographics (
  4. Gout Executive-2016 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive-2016.pdf
    January 01, 2016 - Key Question 1. a. … Key Question 2. … Key Question 1. a. … Key Question 1d. … Key Question 2.
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_surveillance.pdf
    June 01, 2012 - The conclusion(s) for each key question are found in the executive summary of the CER report.1 2 … No new evidence was identified for this question. … Conclusion: 1 of 3 conclusions is possibly out of date Key Question # 3 Signals from studies … identified through update search: No new evidence was identified for this question. … (Yes/No/Don’t know) If yes, please provide references Comments Key Question 1.
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rural-telehealth-amended-protocol.pdf
    February 25, 2021 - Key Question 2. … Key Question 2. … Key Question 2. … Key Question 4. … Key Question 1.
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/diagnostic-error-executive-summary.pdf
    August 01, 2023 - We synthesized results for each question and extrapolated U.S. estimates. … 2), and the chief causes of and risk factors for these errors (Key Question 3). … Results for Key Question 1 relied heavily on two large studies (one of medical malpractice claims, the … Overall (i.e., not disease-specific) error and harm rates for Key Question 2 relied heavily on three … Specific gaps identified for each question, with potential remedies, are described in the full report
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/treatment-resistant-depression_research-protocol.pdf
    December 09, 2009 - ]) • Comparators: ECT, rTMS, VNS, psychotherapy, pharmacologic treatments • Outcomes for each question … We will systematically search, review, and analyze the scientific evidence for each key question and … To identify articles relevant to each key question, we began with a focused MEDLINE search on depression … Grading the Evidence for Each Key Question We will rate the strength of evidence based on the standard … See notes under the key question for the rationale.
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/bereaved-persons-protocol.pdf
    June 01, 2023 - 1), screening tools (Key Question 2), bereavement interventions (Key Question 3), and maladaptive grief-related … Key Question 3: What are the effectiveness, comparative effectiveness, and harms of interventions for … Key Question 4: What are the effectiveness, comparative effectiveness and harms of interventions for … We will tailor the risk of bias assessment to the question the study is used to answers. … Data Synthesis We will answer each key question with the available evidence.
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-staging_research-protocol.pdf
    December 08, 2014 - Quality of life Question 3. … Question 2) • Comparative tumor response (Key Question 2) • Comparative survival (Key QuestionQuestion 2) • Comparative harms due to undertreatment (Key Question 2) • Association between age … (Key Question 3) • Association between tumor characteristics and comparative accuracy (Key Question … This grade is provided separately for each outcome of each comparison of each Key Question.
  11. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/question-what-is-the-etiology-of-cryptorchidism-what-are-the-environmental-factors-maternal-smoking-maternal-diabetes-mellitus-etc-that-may-contribute-to-the-development-of-this-condition-question-what-is-the-ideal-diagnosti
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-iv-nv-hap-protocol.pdf
    August 05, 2024 - Interventions to Prevent Nonventilator Hospital-acquired Pneumonia (NV-HAP) for Inpatients Review Question … Inclusion and Exclusion Criteria for the Review Question Study Parameter Inclusion Criteria Exclusion … Risk of Bias Assessment For studies that address the Review Question about the effectiveness of PSPs … For the Review Question about the effectiveness of PSPs, we will record information about the context … Inclusion and Exclusion Criteria for the Review Question Literature Searches Study Screening Data
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-monitoring-systems-protocol.pdf
    July 01, 2023 - Safer (MHS) IV: Patient Monitoring Systems to Prevent Failure to Rescue Review Questions Review Question … For Contextual Question 4, we will identify publicly available patient safety toolkits developed by … Eligibility Criteria We will search for original studies and systematic reviews on the Review Question … Information will be organized to answer the Review Question and Contextual Questions, and will include … For the Review Question about the effectiveness of PSPs, we will record information about the context
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research-protocol.pdf
    September 01, 2016 - For this project we will focus on the fol- lowing sub-question: Key Question 2a: What is the safety … Published online: September 1, 2016 6 For the first question we will describe all studies … Description of incomplete or discontinued trials (question 3) We will create separate tables for those … studies that are incomplete or discontinued to address Question 3: “For studies in ClinicalTrials.gov … These data will be extracted as above to address this question.
  15. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/healthcare-algorithms-agenda-for-March-23.pdf
    May 29, 2025 - University of Pennsylvania School of Medicine) Focus: Methods for the review and results for Key Question … 1 and Contextual Question 1  What is the effect of healthcare algorithms and algorithm-informed … Brian Leas, MS, MA (University of Pennsylvania School of Medicine) Focus: Results for Contextual Question … Presenter: Brian Leas, MS, MA (University of Pennsylvania School of Medicine) Focus: Results for Key Question … Weissman, MD, MSHP (University of Pennsylvania School of Medicine) Focus: Results for Contextual Question
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/fiber-intake-final-executive-summary.pdf
    July 01, 2025 - The systematic review addressed the following Key Question: Key Question 1: What is the association … Key Question 1a: How does the association vary among people in different life stages? … No study effectively addressed the research question of this review, namely the overall effect of a … Future studies to address the Key Question of this systematic review need to be specifically designed … Key Question 1a: How does the association vary among people in different life stages?
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/gestational-diabetes-screening-diagnosis_disposition-comments.pdf
    January 01, 2020 - We present summary Key Points near the beginning of each key question in the main report. … correctly address this key question. … To the extent possible, this should be addressed in Key Question 5. … We have discussed induction of labor and cesarean section under Key Question 5 as well as Key Question … We have reported on the number of clinic visits in Key Question 5.
  18. effectivehealthcare.ahrq.gov/sites/default/files/protocol-social-isolation.pdf
    January 01, 2013 - framework for Addressing Social Isolation to Improve Health of Older Adults: A Rapid Evidence Review Question … isolation and loneliness Adults 60+ years old Health outcomes Health care utilization Harms Question … An arrow labeled "Question 1" connects "Interventions that target social isolation and loneliness" to … An arrow labeled "Question 2" connects "Interventions that target social isolation and loneliness" to
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/emt-naloxon_research-protocol.pdf
    November 29, 2016 - Key Question 1: For patients with confirmed or suspected opioid overdose, what is the comparative benefit … Key Question 2: For patients with confirmed or suspected opioid overdose in out-of- hospital settings … Key Question 3: For patients with confirmed or suspected opioid overdose in out-of- hospital settings … Key Question 4: For patients with confirmed or suspected opioid overdose in out-of- hospital settings … of different doses of intranasal, intramuscular, and intravenous naloxone o Key Question 2: Titration
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-executive-170523.pdf
    May 01, 2017 - Key Question 1: For children with chronic otitis media with effusion, what is the effectiveness of TT … Key Question 4: Do water precautions reduce the incidence of TT otorrhea or affect quality of life? … Need for water precautions in children with TT (Key Question 4) OME=otitis media with effusion; AOM= … Treatment of otorrhea in children with TT (Key Question 5) OME=otitis media with effusion; AOM=acute … Key Question 2 We identified 8 publications, reporting 7 RCTs and 2 NRCSs.

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