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1301. Comparative effectiveness of conventional computed tomography (CT), multidetector computed tomography (MDCT) (CT colonography), fludeoxyglucose positron emission tomography (FDG-PET) or FDG-PET/CT, magnetic resonance imaging (MRI),… | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/get-involved/nominated-topics/comparative-effectiveness-of-conventional-computed-tomography-ct-multidetector-computed-tomography-mdct-ct-colonography-fludeoxyglucose-positron-emission-tomography-fdg-pet-or-fdg-petct-magnetic-resonance-imaging-mri-ultraso

1302. Stakeholder-Engagement-Benefits White-Paper (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholder-engagement-benefits_white-paper.pdf
      March 01, 2014 - A number of systematic reviewers mentioned the possibility of looking at this question retrospectively … NICE, AHRQ) Keown et al., 200822 Canada Not discussed Not discussed Identification of research question … United Kingdom At the individual level, public involvement is important at initial stages (key question … lot of commitment to actually invite us to participate meaningfully in the development; both of the question … very good about tracking the changes in the questions, for example, which could help us address that question

1303. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia-2011_research-protocol.pdf
      January 01, 2011 - Four KQs will be addressed in our systematic review: Question 1 (Overarching Question) What … If direct evidence is not sufficient to address this question, the overarching question can be indirectly … Question 3 In stages 3–5 nondialysis and dialysis CKD patients with iron-deficiency anemia, what … Question 4 What factors affect the test performance and clinical utility of newer markers of iron … Grading the Evidence for Each Key Question We will follow the AHRQ Methods Guide 32 to evaluate

1304. Title (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-adults-prisons_research-protocol.pdf
      September 13, 2012 - Question 2 was further modified to more clearly indicate the types of community-oriented interventions … Key Question 1 What is the comparative effectiveness of interventions applied within a jail, prison, … Any articles possibly meeting the inclusion criteria for at least one key question will be obtained … 1 and a “yes” on question 2 below and have at least 50 percent of the other items on the checklist … Assessing the Applicability of the Evidence for Each Key Question Applicability will be assessed by

1305. Public-Reporting-Quality-Improvement Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/public-reporting-quality-improvement_research-protocol.pdf
      August 17, 2011 - Key Questions for Objective 1 Question 1 Does public reporting result in improvements in the … Question 2 What harms result from public reporting? B. … Key Questions for Objective 2 Question 3 Does public reporting lead to change in health care … Question 4 Does public reporting lead to change in the behavior of patients, their representatives … Question 6 What contextual factors (population characteristics, decision type, and environmental)

1306. Medical Therapies for Locally Advanced Gastric Adenocarcinoma (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol-amendment.pdf
      May 02, 2025 - human epidermal growth factor receptor 2; HIPEC = hyperthermic intraperitoneal chemotherapy; KQ = key question … gastric adenocarcinoma Abbreviations: HIPEC = hyperthermic intraperitoneal chemotherapy; KQ = key question

1307. Disposition of Comments Report for The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
      September 29, 2014 - criteria, we broadened criteria to discuss evidence on uncontrolled studies for this Key Question … At best the results demonstrate the inadequacy of the evidence to answer the key question. … Suggest dividing into one table for each key question. … Same question for opioids and fractures (I assume mediated through falls)? … Suggestion question B is addressed by the Key Questions in the report.

1308. Tinnitus Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_executive.pdf
      August 01, 2013 - Summary of findings for Key Question 2: Pharmacological or food supplement interventions Outcome # … Summary of findings for Key Question 2: Pharmacological or food supplement interventions (continued … Summary of findings for Key Question 2: Medical interventions Outcome # of Articles Overall Strength … Key Question 2 Population • Include a broader spectrum of adult patients with respect to age, sex … Key Question 3 • Develop studies to evaluate the natural history and prognostic factors in persons

1309. Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias: Future Research Needs (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay-future_research.pdf
      September 01, 2012 - ES-2 • Key Question 1: Does adding the SFLC assay and the kappa/lambda ratio to traditional testing … • Key Question 3: In patients with an existing diagnosis of PCD (MM, nonsecretory MM, or AL amyloidosis … • Key Question 5: In patients with an existing diagnosis of PCD (MM, nonsecretory MM, or AL amyloidosis … Key Question 4 of the CER was, “In patients with an existing diagnosis of PCD (MM, nonsecretory MM, … We therefore rated the strength of evidence as insufficient for this question.

1310. Emergency Medical Service/911 Workforce Infection Control and Prevention Issues (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/ems-911-workforce-protocol.pdf
      January 01, 2015 - For Guiding Question 1, we will define occupationally-acquired exposures to infectious diseases as contact … prevention and control in EMS/911 workforce (IPC = infection prevention and control; KQ = key question … information about the epidemiologic characteristics of the infectious disease exposures (Guiding Question … manufacturers, researchers, payers, or other perspectives, depending on the technology/intervention in question

1311. Peripheral-Artery-Disease-Treatment Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
      May 01, 2013 - Analytic framework Abbreviations: KQ=Key Question; PAD=peripheral artery disease. 5 Registry Platform … The small number 8 Abbreviations: KQ=Key Question; RCT=randomized controlled trial. … Abbreviations: CLI=critical limb ischemia; IC=intermittent claudication; DAPT=dual antiplatelet therapy; KQ=Key Question … therapy HR hazard ratio 39 IC intermittent claudication ICD initial claudication distance KQ Key Question

1312. S77 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/s77.pdf
      October 01, 2007 - This research should not be used to question the des- ignation of the VA pharmacy benefit as creditable

1313. Cannabis-2022-Update-Surv-Rep-1-App-F-5 (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-app-F-5.xlsx
      January 01, 2022 - intensity index; RR = relative risk; SD = standard deviation; SE = standard error; SF-36 = short form 36 question

1314. Cannabis-2022-Surv-Rep-3-Table-F5 (xls file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-3-table-F5.xlsx
      January 01, 2022 - intensity index; RR = relative risk; SD = standard deviation; SE = standard error; SF-36 = short form 36 question

1315. In the area of autism research, the vast majority of clinical trials conducted to date have addressed only the questions of how an individual treatment compares to a placebo. Extremely few studies have been conducted that make head-to-… | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/get-involved/nominated-topics/pin-the-area-of-autism-research-the-vast-majority-of-clinical-trials-conducted-to-date-have-addressed-only-the-questions-of-how-an-individual-treatment-compares-to-a-placebo-extremely-few-studies-have-been-conducted-that-mak

1316. White Paper_Supplementing Systematic Review Findings With Healthcare System Data: Pilot Projects From the Agency for Healthcare Research and Quality Evidence-based Practice Center Program (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/pilot-projects-supplementing-white-paper.pdf
      December 01, 2024 - However, defining the clinical question with the help of clinical experts early in the review process … datasets to determine if the necessary data are available and of sufficient quality to answer a given question

1317. Disposition of Comments Report for Evidence Report 215 Safety of Vaccines Used for Routine Immunization in the United States (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccine-safety_disposition-comments.pdf
      January 01, 2020 - However, the key question regarding degree of severity of the adverse events, though relevant to the … This is a key question in the review but perhaps a statement reflecting that the information will be … The reviewer guessed that one point was given for each specific question in the tool but this was not … TEP # 4 Results—Page 49, Table 5 Similar to comments above, the first part of the key question for … Do the authors mean to indicate that they were not able to answer the first question about collected

1318. For adults and children with asthma what is the effectiveness of the Buteyko Breathing method on reducing bronchodilator and inhaled steroid use and improving health status? | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/get-involved/nominated-topics/for-adults-and-children-with-asthma-what-is-the-effectiveness-of-the-buteyko-breathing-method-on-reducing-bronchodilator-and-inhaled-steroid-use-and-improving-health-status

1319. In patients with dementia, what is the effectiveness of psychological treatment (i.e., non-pharmacological; e.g., cognitive or behavioral therapy for individuals with dementia; environmental and behavioral interventions to address… | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/get-involved/nominated-topics/in-patients-with-dementia-what-is-the-effectiveness-of-psychological-treatment-ie-non-pharmacological-eg-cognitive-or-behavioral-therapy-for-individuals-with-dementia-environmental-and-behavioral-interventions-to-address-beh

1320. What is the comparative effectiveness of different models of survivorship care and sets of services on late and long-term net health outcomes (e.g., for breast cancer)? | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-is-the-comparative-effectiveness-of-different-models-of-survivorship-care-and-sets-of-services-on-late-and-long-term-net-health-outcomes-eg-for-breast-cancer