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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-appendix-3.xlsx
June 24, 2022 - Frame the question, which may involve use of a PICOTS framework
Pearson Data Curate real world data … and/or develop the plan for data acquisition sufficient answer the question to meet the evidentiary … The specific clinical question of interest drives the consideration regarding whether an RWE approach … is sufficient and robust enough for the regulatory question at hand. … That is, are the data relevant and fit for purpose for the research question at hand?
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
February 01, 2013 - Summary of Evidence
There is insufficient evidence to answer this Key Question. … Summary of Evidence
There is insufficient evidence to answer this Key Question. … All studies addressing
this Key Question evaluated IVUS only. … The summary of evidence for each Key Question is
provided in Table C. … addressed Key Question 3.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
March 01, 2012 - Key Question 2. … Key Question 3. … Key Question 4. … Key Question 5a. … Key Question 5b.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_executive.pdf
September 01, 2014 - Key Question 1. … Key Question 1a. … Key Question 1b. … Key Question 1e. … Key Question 2.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/tethered-spinal-cord-protocol.pdf
July 19, 2023 - 1), prophylactic treatment (Key Question 2), symptomatic treatment (Key
Question 3), and repeat surgery … Following the described input, the final key questions are as follows:
Key Question 1: What is the … Key Question 4: Among individuals who experience retethering after spinal
detethering surgery, what … as defined by the
reference standard does not fully match the review question. … We will stratify key
question 3 (treatment) by symptom type, intensity, and patient age.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2022-update-app-g1.xlsx
January 01, 2022 - 2.4) (If Y, PY to previous question) were these deviations likely to have affected the outcome? … 2.7) (If N, PN, NI to previous question) Was there potential for a substantial impact (on the result) … 3.3) (If N/PN to previous question) Could missingness in the outcome depend on its true value? … 3.4) (If Y, PY, NI to previous question) Is it likely that missingness in the outcome depended on its … 4.5) (If Y/PY/NI to previous question) Is it likely that assessment of the outcome was influenced by
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effectivehealthcare.ahrq.gov/sites/default/files/c-diff-infections-nomination-140925.pdf
February 19, 2014 - Topic Description
Key Questions: Key Question 1: How do different methods for detection of toxigenic … B
§ Gene detection tests versus immunoassays for toxins A and B
§ Patient characteristics
Key Question … alcohol gel
§ Disinfection
§ Sustainability
§ Risk factors
§ Multiple component strategies
Key Question … treatment
§ Strain of organism
§ Patient characteristics
§ Resistance of other pathogens
Key Question
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0765-150129.pdf
November 03, 2014 - Key Question #1: What is the comparative effectiveness of tympanostomy tubes in
children with chronic … hearing levels (HLs); speech and language improvement; health-related quality of life
(HRQoL)
Key Question … Key Questions
from Nominator:
Key Question … indications for tympanostomy; patient satisfaction with the
change in hearing following surgery
Key Question … of TTO duration or recurrence; prevention of other
complications; school absenteeism; HRQoL
Key Question
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
March 01, 2011 - Below we provide additional summary information for
selected comparisons of interest by key question, … Key Question 1: Intermediate Outcomes
Intermediate clinical outcomes were the most
frequently evaluated … Therefore, most
comparisons for this key question had a low strength of
evidence. … Key Question 3: Adverse Events and Side Effects
This Key Question was addressed by 107 studies. … Key Question 4: Differences in Subgroups
Twenty-eight studies applied to Key Question 4.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-protocol-amendment.pdf
March 22, 2023 - Key Question 1. … Key Question 2. … Key Question 3. … Key Question 4. … Key Question 6:
Key Question 6a.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
October 01, 2014 - Key Question 1. … Key Question 2. … Key Question 3. … Key Question 1. … Key Question 2.
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effectivehealthcare.ahrq.gov/sites/default/files/module-iv-skills-for-successful-engagement.pdf
May 29, 2025 - Focused on process
§ (Picture of books on a pedestal) Knowledgeable about the topic
§ (Picture of a question … However, the facilitator
should be knowledgeable or skilled enough to question, probe, and approach … Slide 25
Module IV Quiz:
Question 1
One of the challenges to stakeholder engagement is engaging … • Only allow discussion and input to occur during scheduled meetings
Slide 29
Module IV Quiz:
Question … process focused on group dynamics and processes
• A superfluous skill
Slide 30
Module IV Quiz:
Question
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation-surveillance-160902.pdf
May 29, 2025 - "
Key$Question$3." … "
Key$Question$4." … "
Key$Question$5." … $Key$Question$2a. … $Key$Question$2c.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/type-2-diabetes-medications-update_research-protocol.pdf
April 06, 2010 - The Key Questions
Key Question 1: In adults age 18 or older with type 2 diabetes mellitus, what is the … Outcomes for each question
The outcomes for Key Question 1 are:
• HgbA1c
• Weight
• Low density … □ For Key Question 1, we included the following outcomes: HgbA1c, weight, and serum lipid levels ( … □ For Key Question 3, we included the following outcomes: hypoglycemia, liver injury, congestive … □ For Key Question 1, we included only RCTs.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_research-protocol.pdf
October 01, 2013 - dose/volume and number of doses)
Comparators
Key Question 1 and Key Question 2 (see Table 2)
● … Key Question 3 and Key Question 4 (see Table 3)
● IOCM versus LOCM
● LOCM versus LOCM
● IOCM (by … Setting
● Key Question 1 through Key Question 4
● Inpatient and outpatient populations
Source: www.effectivehealthcare.ahrq.gov … Major prevention interventions and comparisons for Key Question 1 and Key Question 2
(These are the … Major contrast media and comparisons for Key Question 3 and Key Question 4
(These are the important
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiation-therapy-brain-metases-protocol.pdf
October 10, 2019 - In addition, all subquestions for Key Question 1 were also added to Key
Question 2, and vice versa. … Analysis plan for Key question 4: For Key Question 4, the synthesis will focus on key
adverse events … For key question 2, the analysis will be
centered around SRS as initial treatment. … For key question 3, the analysis will focus on
postoperative treatment. … Box 1: Key Outcomes
Outcomes for Key Question 4 (adverse events)
1.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-2007_executive.pdf
January 01, 2007 - 3
Key Question 2. … Key Question 3. … Key Question 1. … Key Question 2. … Key Question 3.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/mass-casualty-events-scarce-resources_executive.pdf
June 01, 2012 - This report addresses the following Key Questions:
Key Question 1. … Key Question 2. … Key Question 3. … Key Question 4. … Our data extraction approach was tailored to each Key
Question.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-future_research.pdf
October 26, 2012 - The PICOTS on
this question will
depend on study
question and
design
2.3 To what extent … The PICOTS on
this question will
depend on study
question and
design
2.3 To what extent … The
study design evaluations for this question was combined with research question number 4.1 as … question number 4.1
below. … The study design evaluations for
this question was combined with research question number 2.1 as they
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0768-141211.pdf
October 23, 2014 - Key Question #1: What is the comparative effectiveness of tonsillectomy in children
with recurrent throat … Outcome(s): Number of throat infections, complications of infection, or complications of
surgery
Key Question … Key Question … In consultation with our clinical reviewer, the scope of this topic from the original
nominator question