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81. For patients with allergic disease, what is the comparative effectiveness of improving health outcomes and lowering healthcare utilization by treating their disease with sublingual immunotherapy (allergy drops taken under the tongue) as… | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/for-patients-with-allergic-disease-what-is-the-comparative-effectiveness-of-improving-health-outcomes-and-lowering-healthcare-utilization-by-treating-their-disease-with-sublingual-immunotherapy-allergy-drops-taken-under-the-
    November 01, 2017 - Does your question include a comparison of different health care approaches? … What patients or group(s) of patients does your question apply to? … Are there subgroups of patients that your question might apply to? … What specifically motivated you to ask this question? … Describe the timeframe in which an answer to your question is needed.

82. • Measurement and outcomes need consensus definitions • State Medicaid programs need robust HEDIS and NCQA measures for all severe and persistent mental health conditions. • Consensus definitions would help answer questions such as “Does… | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/measurement-and-outcomes-need-consensus-definitions-state-medicaid-programs-need-robust-hedis-and-ncqa-measures-for-all-severe-and-persistent-mental-health-conditions-consensus-definitions-would-help-answer-questions-such-as
    November 01, 2017 - Does your question include a comparison of different health care approaches? … What patients or group(s) of patients does your question apply to? … Outcomes information can be used What specifically motivated you to ask this question? … Does your question represent uncertainty for clinicians and/or policy-makers? … Describe the timeframe in which an answer to your question is needed. As soon as possible.

83. Inguinal-Hernia Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/inguinal-hernia_executive.pdf
    August 01, 2012 - Key Question 3. … Key Question 4. … Key Question 5. … Key Question 6. … Key Question 7.

84. Disposition of Comments_Technical Brief No. 43: Measuring Healthcare Organization Characteristics in Cancer Care Delivery Research (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/organization-cancer-care-disposition-comments.pdf
    June 20, 2023 - We added a table 4 of Guiding Question 2 approaches. … We have added callouts to identify which question is under discussion. … We removed reference to Guiding Question 3 in the introduction to Guiding Question 2. … We added a figure for Guiding Question 2 themes that is similar to Figure 6 (for Guiding Question … Just raising the question.

85. Cervical Ripening in the Outpatient Setting (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ocr-protocol-final_1.pdf
    December 18, 2019 - Question 3: Outpatient comparison of methods Inclusion Key Question 4: Fetal Surveillance Exclusion … Question 3: Outpatient comparison of methods Inclusion Key Question 4: Fetal Surveillance Exclusion … Question 3: Outpatient comparison of methods Inclusion Key Question 4: Fetal Surveillance Exclusion … Question 3: Outpatient comparison of methods Inclusion Key Question 4: Fetal Surveillance Exclusion … Question 3: Outpatient comparison of methods Inclusion Key Question 4: Fetal Surveillance Exclusion

86. 1. What is the etiology of acute and chronic urinary retention in adults? 2. How do we define urinary retention (base case) including those with known neurologic problems? (aka What is considered abnormal PVR?) 3. What is the natural… | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/1-what-is-the-etiology-of-acute-and-chronic-urinary-retention-in-adults-2-how-do-we-define-urinary-retention-base-case-including-those-with-known-neurologic-problems-aka-what-is-considered-abnormal-pvr-3-what-is-the-natural-
    November 01, 2017 - Topic Suggestion Disposition (PDF, 129.5 KB) Briefly describe a specific question … Does your question include a comparison of different health care approaches? … Adult men and women Are there subgroups of patients that your question might apply to? … Does your question represent uncertainty for clinicians and/or policy-makers? … Potential Impact How will an answer to your research question be used or help inform decisions for

87. 1. Which patients benefit the most from MTM services? 1.1. Which factors, or combinations of factors, are most predictive of the clinical benefit of MTM services? 1.1.1. Disease factors (e.g., diabetes vs COPD ; multi-morbidity vs single… | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/1-which-patients-benefit-the-most-from-mtm-services-11-which-factors-or-combinations-of-factors-are-most-predictive-of-the-clinical-benefit-of-mtm-services-111-disease-factors-eg-diabetes-vs-copd-multi-morbidity-vs-single-di
    November 01, 2017 - 2.4.What is the optimal frequency of follow-up consultations after the in Does your question include … What patients or group(s) of patients does your question apply to? … Are there subgroups of patients that your question might apply to? … Does your question represent uncertainty for clinicians and/or policy-makers? … Describe the timeframe in which an answer to your question is needed. As soon as possible.

88. The American College of Chest Physicians (ACCP) proposes to update the following 4 guideline topics from the 2006 publication on the Diagnosis and Management of Cough: ACCP Evidence-Based Clinical Practice Guidelines.1 1. Assessing Cough… | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/the-american-college-of-chest-physicians-accp-proposes-to-update-the-following-4-guideline-topics-from-the-2006-publication-on-the-diagnosis-and-management-of-cough-accp-evidence-based-clinical-practice-guidelines1-1-assessi
    November 01, 2017 - What patients or group(s) of patients does your question apply to? … Appropriateness for EHC Program Does your question include a health care drug, intervention, device … What specifically motivated you to ask this question? … Potential Impact How will an answer to your research question be used or help inform decisions for … Describe the timeframe in which an answer to your question is needed.

89. Frameworks for Determining Research Gaps During Systematic Reviews (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-future-research-steps-framework_research.pdf
    June 01, 2011 - Key Question Number and Key Question Topic • Research Gap Number • Reason for Gap • Population (P … The JHU EPC was assigned question 1, which is the following question: Define frameworks for determining … We suggest use of the same format as above, but Key Question Number and Key Question Topic would be … Question: When Was This Process Initiated? … Number and Key Question Topic Research Question Limitations and Future Research Conclusions Background

90. Musculoskeletal-Complaints-Tests-Children Surveillance (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/musculoskeletal-complaints-tests-children_surveillance.pdf
    January 08, 2013 - Key Question 3.2. … Key Question 3.5. … Do Not Know Key Question 1. Prevalence and Incidence Key Question 1.1. … Key Question 3.2. … Key Question 3.5.

91. Comparative Effectiveness Reiew 243_Prehospital Airway Management: A Systematic Review (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-243-prehospital-airway-management-evidence-summary_0.pdf
    June 01, 2021 - three airway management approaches by emergency medical services in the prehospital setting: Key Question … 1 – bag valve mask [BVM] versus supraglottic airway [SGA]; Key Question 2 – BVM versus endotracheal … intubation [ETI]); Key Question 3 – SGA versus ETI; and Key Question 4 – how the benefits and harms … 1, 22 studies), BVM to ETI (Key Question 2, 22 studies), SGA to ETI (Key Question 3, 41 studies), or … compared variations of one of the three airway approaches (Key Question 4, 51 studies).

92. Evidence Summary: Comparative Effectiveness Review No. 238: Cervical Ripening (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-238-cervical-ripening-evidence-summary.pdf
    March 01, 2021 - Primary birth outcome: cesarean delivery Key Question Intervention Findingsa Studies Incidence Relative … Risk (95% CI) I2 for Pooled Analysesb Key Question 1: Prostaglandin Outpatient vs. … Primary fetal harms outcomes Key Question Intervention Outcome Findingsa Studies Incidence Relative … Risk (95% CI) I2 for Pooled Analysesb Key Question 1: Prostaglandin Outpatient vs. … Risk (95% CI) I2 for pooled analysesb Key Question 2: Mechanical Method Outpatient vs.

93. Executive Summary: Radiation Therapy for Metastatic Bone Disease: Effectiveness and Harms (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-summary.pdf
    August 01, 2023 - For Key Question 2 (re-irradiation), two RCTs and three NRSIs met inclusion criteria; for Key Question … EBRT alone), nine RCTs and seven NRSIs; and for Key Question 3c (EBRT plus another modality vs. the … Key Question 1 compared EBRT dose-fraction schemes and delivery of initial palliative radiation for … Evidence for Key Question 2 on dose-fraction schemes and delivery for re-irradiation was sparse. … Comparative evidence for Key Question 3 on EBRT in conjunction with additional therapies was sparse.

94. Comparative Effectiveness of Screening for Glaucoma | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/glaucoma-screening/research-protocol
    December 01, 2019 - (Key Question 6) Key Questions Screening for a medical condition in asymptomatic individuals is … Key Question 3 What is the predictive value of screening tests for open-angle glaucoma? … Key Question 6 What are the harms associated with screening for open-angle glaucoma? … There will be no minimum length of follow-up for outcomes related to Key Question 3. … For Key Question 3, we will calculate diagnostic odds ratios.

95. In the area of autism research, the vast majority of clinical trials conducted to date have addressed only the questions of how an individual treatment compares to a placebo. Extremely few studies have been conducted that make head-to-… | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/pin-the-area-of-autism-research-the-vast-majority-of-clinical-trials-conducted-to-date-have-addressed-only-the-questions-of-how-an-individual-treatment-compares-to-a-placebo-extremely-few-studies-have-been-conducted-that-mak
    November 01, 2017 - What specifically motivated you to ask this question? … Does your question represent uncertainty for clinicians and/or policy-makers? … Potential Impact How will an answer to your research question be used or help inform decisions for … Describe the timeframe in which an answer to your question is needed. … Describe any health disparities, inequities, or impact on vulnerable populations your question applies

96. Quality-Gap-Palliative-Hospice Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/quality-gap-palliative-hospice_executive.pdf
    October 01, 2012 - of Key Question 2. … Note: KQ = Key Question. … Key Question 2b: Evidence About Integrative and Consultative Models This Key Question was not analyzed … Key Question 2b: Evidence About Integrative and Consultative Models This Key Question was not analyzed … Key Question 2a: Evidence About Types of Quality Improvement This Key Question was not analyzed for

97. Public-Reporting-Quality-Improvement Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/public-reporting-quality-improvement_executive.pdf
    July 01, 2012 - Key Question 2 What harms result from public reporting? … • Outcomes (specified for each Key Question) – Key Question 1. … – Key Question 2. … – Key Question 3. … – Key Question 4.

98. Strategies for Integrating Behavioral Health and Primary Care | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/strategies-integrating-behavioral-health/protocol
    December 01, 2024 - Scan Question (1). … Key Question (2) and Sub-question 5a. … Scan Question. … Key Question (2) and Question 5a . … Key Question 2 and Question 5a.

99. For adult patients with bipolar disorder (including bipolar I and bipolar II disorder), what is the comparative effectiveness of available treatments including psychotherapy, other psychosocial treatments, medications, and other somatic… | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/for-adult-patients-with-bipolar-disorder-including-bipolar-i-and-bipolar-ii-disorder-what-is-the-comparative-effectiveness-of-available-treatments-including-psychotherapy-other-psychosocial-treatments-medications-and-other-s
    November 01, 2017 - Topic Suggestion Disposition (PDF, 1.2 MB) Briefly describe a specific question … Does your question include a comparison of different health care approaches? … Does your question represent uncertainty for clinicians and/or policy-makers? … Describe the timeframe in which an answer to your question is needed. … Describe any health disparities, inequities, or impact on vulnerable populations your question applies

100. Case-Management Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/case-management_executive.pdf
     January 01, 2013 - Key Question 1a. … Key Question 1b. … Key Question 1c. … Key Question 3. … Low Key Question 1a HIV Mortality.