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  1. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0411_02-10-2011.pdf
    January 01, 2011 - Nominators: 3 health care professional associations Nomination Summary: The nominators question … In addition, they question whether the benefits and harms of these tests vary by the risk of the surgical
  2. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
    November 01, 2012 - Key Question 2 a. … Key Question 3 a. What are the comparative harms associated with antiviral treatments? b. … Search Strategy and Study Selection To identify articles relevant to each Key Question, a research … We did not perform meta-analyses for Key Question 4 because all studies were observational and had … Low Key Question 3b Do these harms differ according to patient subgroup characteristics?
  3. CERs Report cover (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/future05-breastcancer-10-5-2010final.pdf
    September 01, 2010 - Because two of these priority topic areas, interventions extending beyond medications (Question B) … /Researcher) (Question not asked of Consumer/Policymaker) Q8. … the acceptability and effectiveness of risk reduction treatment (Research Question C)? … C 30 Framework Question(s) Priority Research Area (Question) Research Needed And Potential … For two of these high-priority topics—intervention (Question B) and influencing factors (Question C
  4. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/case-management_research-protocol.pdf
    June 06, 2011 - Grading the Evidence for Each Key Question We will use the chapter, Grading the Strength of a Body … than one category, and the revised Key Questions now group the outcome categories as parts of Key Question … Revised Key Questions: Key Question 1: In adults with chronic medical illness and complex care … Key Question 2: Does the effectiveness of CM differ according to patient characteristics, including … Key Question 3: Does the effectiveness of CM differ according to intervention characteristics, including
  5. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
    April 01, 2013 - Stakeholders assigned a total of seven “stars” (up to three stars for one question) to methodological … The recent guideline report from the Canadian Headache Society addressed the question of how long to … Research Design Considerations This question might be considered a subquestion to an RCT addressing … This question is relevant for chronic as well as episodic migraine populations. … This question is relevant for chronic as well as episodic migraine populations.
  6. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/kidney-disease-medicine_research-protocol.pdf
    November 01, 2010 - KEY QUESTION 1: In asymptomatic adults with or without recognized risk factors for chronic kidney … Systematic reviews will be included if the research question is considered relevant as outlined in … Evidence tables will be organized by key question. … Data Synthesis We will present results in evidence and summary tables organized by key question. … Grading the Evidence for Each Key Question The strength of the evidence for each key question will
  7. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/dietary-supplements_surveillance.pdf
    January 01, 2013 - Key Question 1a. … Do Not Know Key Question 1. … Do Not Know Key Question 2. … New Evidence: Key Question 4. … Key Question 4a.
  8. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/alcohol-misuse_research-protocol.pdf
    April 28, 2010 - Question (SASQ). … Question 4 a. … Question 5 Source: www.effectivehealthcare.ahrq.gov Published Online: July 21, 2011 6 … Source: www.effectivehealthcare.ahrq.gov Published Online: July 21, 2011 7 Question 6 How … Contextual Question For this report, we will address the question of whether there are effective
  9. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
    May 24, 2010 - The Key Questions Question 1: How do different methods for detection of toxigenic C. difficile to … Question 2: What are effective prevention strategies? a. … Question 3: What is the comparative effectiveness and harms of different antibiotic treatments? a. … Question 4: What are the effectiveness and harms of non-antibiotic adjunctive interventions? a. … • Outcomes for each question: Diagnostic Test Outcomes 1. Sensitivity 2. Specificity 3.
  10. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/abnormal-uterine-bleeding_research-protocol.pdf
    November 21, 2011 - Key Question 2: What are the harms, including adverse events, associated with medical, behavioral, … Time period Studies published in or after 1980 Admissible designs  For Key Question 1A and Key … 2, eligible study designs will include those noted for Key Question 1A and Key Question 1B and uncontrolled … The evidence table dimensions (i.e., the columns) may vary by Key Question as appropriate. … Grading the Evidence for Each Key Question – Strength of evidence: We will use explicit criteria
  11. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_executive.pdf
    April 01, 2013 - This report addresses the following Key Questions: Key Question 1. … Key Question 2. … Key Question 3. … Conclusions Evidence from three groups of trials were summarized and analyzed for Key Question 1. … results from a meta-analysis of individual patient data.3 Additionally, three trials included in Key Question
  12. Layout 1 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
    October 01, 2011 - The following Key Questions are the focus of our report: Key Question 1 What are the comparative benefits … Key Question 3 What are the comparative effects of coprescribing H2 receptor antagonists, misoprostol … We assessed the overall strength of evidence for a body of literature about a particular Key Question … We rated the strength of evidence for each Key Question using the four categories recommended in the … Summary of evidence on comparative benefits and harms of analgesics for osteoarthritis Key Question
  13. effectivehealthcare-admin.ahrq.gov/system/files/docs/acute-diverticulitis-topic-nomination.pdf
    August 13, 2018 - Key Questions and PICOTS The key questions for this nomination are: Key Question 1: What are the … 3 Key Question 3: What are the benefits and harms of distant colonoscopy following an episode of acute … Key Question 4: What are the benefits and harms of interventional versus surgical management of recurrent … Key Questions and Results for Duplication and Feasibility Key Question Duplication (08/2015-04/2018 … Abbreviations: AHRQ=Agency for Healthcare Research and Quality; KQ=Key Question; ACP=America College
  14. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-200-post-acs-depression.pdf
    November 01, 2017 - Analytic framework Abbreviations: ACS=acute coronary syndrome; GI=gastrointestinal; KQ=Key Question; … Key Question 1 evidence summary Number of studies: 6 Study publication years: 2005-2013 Number of patients … Key Question 2 evidence summary Number of randomized clinical trials: 4 Number of patients: 3,119 Men … Strength of evidence for Key Question 2: CBT and second-generation antidepressant versus usual care … Strength of evidence for Key Question 2: Antidepressant medication versus usual care Outcome Number
  15. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cerebral-palsy-feeding_executive.pdf
    March 01, 2013 - Key Question 1b. … Key Question 2a. … Key Question 2b. … Key Question 3a. … Key Question 3b.
  16. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/menopause_research-protocol.pdf
    March 25, 2012 - The Key Questions Question 1 What is the comparative effectiveness of different treatments for … Question 4 Does effectiveness and adverse effects vary among subgroups of patients defined by … The Key Questions Question 1 Question 2 Question 3 Question 4 Population(s), Interventions, Comparators … Criteria for Inclusion/Exclusion of Studies in the Review Key Question 1—Symptom Relief Key Question … Grading the Evidence for Each Key Question G. Assessing Applicability V. References VII.
  17. Layout 1 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hypothyroidism-hyperthyroidism-screening-treatment_executive.pdf
    October 01, 2011 - Key Question 2. What are the harms of screening? … Key Question 3. … Key Question 4. … Key Question 3. … Key Question 4.
  18. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-biopsy_disposition-comments.pdf
    March 11, 2010 - Methods p. 18 add “for Question 3 due to the nature of the question and lack of published data on the … of the question, which asks for cosmetic results to be presented there. … Results Add strength of evidence ratings to Key Question 3. … Therefore we approached the question as an “opinion/discussion” question rather than an “evidence” … question.
  19. Layout 1 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
    January 01, 2007 - These specific research issues are grouped by key question below. … For Key Question 1 (proximal clinical outcomes) Future studies should examine effects of medications … For Key Question 6 (differences across specific populations) To determine differences in medication … NA Studies had too few analyses to draw comparative conclusions for this question. 1 Definitions of … 1 (proximal clinical For Key Question 2 (distal diabetes-related For Key Question 3 (quality of life
  20. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medical-test-reviews-options-summarizing.ppt
    June 01, 2012 - True False Practice Question 1 (1 of 2) Practice Question 1 (1 of 2) Explanation for Question 1: … Practice Question 2 (1 of 2) Practice Question 2 (1 of 2) Explanation for Question 2: The correct … Practice Question 3 (1 of 2) Practice Question 3 (1 of 2) Explanation for Question 3: The correct … Practice Question 3 (2 of 2) Practice Question 3 (2 of 2) When evaluating a medical test with no … True False Practice Question 4 (1 of 2) Practice Question 4 (1 of 2) Explanation for Question 4:

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