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101. Comparative Effectiveness Review No. 262_Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings: Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-summary.pdf
     November 01, 2023 - Eligibility criteria for studies for each Key Question are described in the full report. … Key Question 1 included 111 studies, Key Question 2 included 31 studies, Key Question 3 included 99 … studies, Key Question 4 included 1 study, and Key Question 5 included 9 studies. … Key Question 2: Health Outcomes. … We also eliminated a Key Question on pharmacogenomics that was in the original review.

102. Digestible Carbohydrate Intake and Maternal-Infant Outcomes: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/carbohydrate-intake/draft-report
     March 01, 2025 - 1) and gestational weight gain (Key Question 2); and between infant digestible carbohydrate intake and … infant growth, size, body composition from birth to 24 months of age (Key Question 3). … infant weight, length, or head circumference or size (small or large for gestational age) at birth (Key Question … gestational weight gain given different amounts of digestible carbohydrate intake during pregnancy (Key Question … head circumference) and body mass index or other body composition outcomes up to 24 months of age (Key Question

103. Disposition of Comments: CER 228, Nonopioid Pharmacologic Treatments for Chronic Pain (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-228-nonopioid-pharm-chronic-pain-comments.pdf
     April 16, 2020 - Public Reviewer 6 Anna Bono Question 1 Personal anecdote including potentially private information … Public Reviewer 1 Karl Lorenz Question 2 I find it quite problematic: That you omit studies of “end … Public Reviewer 4 Jacob Marzalik, American Psychological Association Question 2 We appreciate the … Public Reviewer 6 Anna Bono Question 4 Several studies in controlled settings have concluded that … Public Reviewer 7 Anonymous Question 9 Thank you for this important contribution.

104. AHRQ Slide Template-Widescreen
     effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-maternal-health-grand-rounds-slides.pptx
     January 01, 2023 - Agency for Healthcare Research and Quality (Rockville, Maryland, USA). 2023. 22 Key Question 1 What … 23 Key Question 1 – Population and Intervention Targets Population Postpartum (≤1 year after giving … group Nonrandomized comparative studies (NRCSs) N≥30 per group (prospective or retrospective) Key Question … 1 – U.S. or Canada only Key Question 2 – U.S. only 28 Evidence Identified (92 studies) Key Question … Key Question 3 What are the comparative effectiveness and harms of alternative magnesium sulfate (MgSO4

105. Evidence Report on the (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
     May 19, 2010 - Population: Same as in Question 1 Intervention: Same as in Question 1 Comparator: Same as in Question … Timing: Same as in Question 1 Settings: Same as in Question 1 Question 3: What subset of the population … Timing: Same as in Question 1 Settings: Same as in Question 1 Question 4: What are the potential … Population: Same as in Question 1 Intervention: Same as in Question 1 Comparator: Same as in Question … Population: Same as in Question 1 Intervention: Same as in Question 1 Comparator: Same as in Question

106. Comparative Effectiveness of Second Generation Antidepressants in the Pharmacologic Treatment of Adult Depression – An Update to a 2007 Report | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/antidepressants-update/research-protocol
     December 01, 2019 - KQ4b: Key question 4a extends the scope of KQ1c to explore differences between immediate and extended … Exhibit 4-1 below presents the inclusion/exclusion criteria for each key question that we used in the … We will systematically search, review, and analyze the scientific evidence for each key question and … Grading the Evidence for Each Key Question We will prioritize outcomes of interest for each key question … harms; and key question 5 will also rate comparative harms.

107. Comparative Effectiveness Review No. 266_Cervical Degenerative Disease Treatment: A Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-266-cdd-executive-summary.pdf
     November 01, 2023 - ACDF in patients with cervical spondylotic radiculopathy or myelopathy at one or two levels (the Key Question … Main findings are summarized by Key Question in Table A. … Summary of findings: cervical degenerative disease treatment Key Question Comparison Fusion; Effect … Similar (++) AEs: Moderate to Large, favors laminoplasty (+) 5 Key Question … Insufficient Small, favoring PEEK (+) No evidence Insufficient 6 Key Question

108. Dietary Saturated Fat Replacement and Plasma Lipid and Cardiovascular Events (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/saturated-fat-replacement-protocol.pdf
     January 01, 2024 - Key Questions This systematic review will examine the Key Question as outlined below, based on the … Key Question 1: What are the effects of replacing dietary intake of total or individual saturated fatty … Key Question 2: What are the effects of replacing dietary intake of total or individual saturated fatty … 1 only) o Children and adolescents (for Key Question 1 only) o Adults (19-64) o Older adults (≥ … Review of Key Question The Joint Canada-U.S.

109. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mhs-IV-surgical-report-cards.pdf
     July 01, 2023 - For Review Question 2, we will focus on identifying relevant measures that are included in the Centers … including PSPs used and explanations of the rationale presented in the studies we find for Review Question … For Review Question 8, we will identify publicly available patient safety toolkits developed by AHRQ … For Review Question 2, we will focus on identifying relevant measures that are ... … For Review Question 8, we will identify publicly available patient safety toolkits developed by AHRQ

110. Dietary Saturated Fat Replacement and Plasma Lipid and Cardiovascular Events | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/saturated-fat-replacement/protocol
     November 01, 2024 - Review of Key Question VIII. Technical Expert Panel (TEP) IX. Peer Reviewers X. … Key Question 1: What are the effects of replacing dietary intake of total or individual saturated fatty … 1 only) Children and adolescents (for Key Question 1 only) Adults (19-64) Older adults (≥65) Pregnant … Key Question 2 Minimum follow-up If population has no CV risk factors: 10 years If population has one … Review of Key Question The Joint Canada-U.S.

111. Treatments for Adults with Schizophrenia | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/schizophrenia-adult/research-protocol
     September 01, 2019 - Key Question 1a What are the comparative benefits and harms of pharmacological treatments for adults … Key Question 2a What are the benefits and harms of psychosocial and other non-pharmacological treatments … (and include all eligible interventions for the key question), include studies that meet the PICOTS … For Key Question 2 on nonpharmacological interventions, search dates will not be restricted. … As there are large, high quality systematic reviews of the interventions in Key Question 1 that have

112. Diagnosis and Treatment of Localized Muscle Invasive Bladder Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/diagnosis-treatment-localized-muscle-invasive-bladder-cancer
     November 01, 2020 - Does your question include a comparison of different health care approaches? … Are there subgroups of patients that your question might apply to? … (National Cancer Institute 2010 What specifically motivated you to ask this question? … Additional patient and medical prov Does your question represent uncertainty for clinicians and/or … Describe the timeframe in which an answer to your question is needed. The AUA is flexible.

113. Facilitation (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/delilberative-methods-design-gupta-2.pdf
     January 11, 2017 - and establish priorities for action Slide 24 Six Facilitator Choices  As a “reaction” question …  As a new starting question  Let there be silence  Move on  Paraphrase  Ask a “probing” or … “follow-up” question Slide 25 Planning Considerations  Who will you ask to facilitate deliberation

114. Attention Deficit Hyperactivity Disorder: Effectiveness of Treatment in At-risk Preschoolers; Long-term Effectiveness in All Ages; and Variability in Prevalence, Diagnosis, and Treatment | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/adhd/research-protocol
     December 01, 2019 - This question was added to the review. a. … Question 2. … Question 3. … PICO table for ADHD Review PICO Question 1 Question 2 Question 3 Population … For question three, we will also include cross-sectional reports.

115. Comparative Effectiveness Review No. 241_Physical Activity and the Health of Wheelchair Users: A Systematic Review in Multiple Sclerosis, Cerebral Palsy, and Spinal Cord Injury (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-241-physical-activity-wheelchair-evidence-summary-updated.pdf
     October 01, 2021 - Key Question 1: Prevention of Cardiovascular Conditions, Diabetes, and Obesity No included study … Key Question 2: Benefits and Harms Compared with no physical activity or usual care, physical activity … https://effectivehealthcare.ahrq.gov/topics/cer-methods-guide/overview 3 Key Question … 1: Prevention of Cardiovascular Conditions, Diabetes, and Obesity Key Question 2: Benefits and Harms … Key Question 3: Patient Factors Affecting Benefits and Harms Limitations Key Question 4: Methodological

116. Dietary Intake of Polyunsaturated Fatty Acids and Plasma Lipid and Cardiovascular Events (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/polyunsaturated-fatty-protocol.pdf
     January 01, 2024 - Key Question 1: What are the effects of different dietary polyunsaturated fatty acid intake on plasma … 1 ● Children and adults Key Question 2 ● Adults (≥18 years old) Both Key Questions ● Participants … 1 only) o Children and adolescents (for Key Question 1 only) o Adults (19-64) o Older adults (≥ … Key Question 2 ● Minimum follow-up o If population has no CV risk factors (or unselected general … Review of Key Question The Joint Canada-U.S.

117. Disposition of Comments: Management of Colonic Diverticulitis (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/diverticulitis-comments.pdf
     October 12, 2020 - It is quite likely that there are insufficient data to answer this question, but it seems like a question … related to diet may be worth considering under this key question. … Unfortunately, this was not included in the protocol as a Key Question of interest. … KI and TEP discussions did not raise this as a Key Question to add. … Key Question 2b (p.24): As with Key Question 2a, we suggest checking for consistency in how findings

118. Slide 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/cf_deliberativemethodswebinar_facilitation.pdf
     May 18, 2012 - common ground and establish priorities for action 2 Six Facilitator Choices Ask a “reaction” question … Ask a new starting question Let there be silence Move on Paraphrase Ask a “probing” or “follow-up … ” question 3 Planning Considerations • Who will you ask to facilitate deliberation?

119. Dietary Intake of Polyunsaturated Fatty Acids and Plasma Lipid and Cardiovascular Events | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/polyunsaturated-fatty/protocol
     November 01, 2024 - Review of Key Question VIII. Technical Expert Panel (TEP) IX. Peer Reviewers X. … Key Question 1: What are the effects of different dietary polyunsaturated fatty acid intake on plasma … 1 only) Children and adolescents (for Key Question 1 only) Adults (19-64) Older adults (≥65) Pregnant … Key Question 2 Minimum follow-up If population has no CV risk factors (or unselected general population … Review of Key Question The Joint Canada-U.S.

120. Strategies for Integrating Behavioral Health and Primary Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/strategies-integrating-behavioral-health-protocol.pdf
     August 04, 2022 - Key Question (2) and Sub-question 5a. … Scan Question. … Key Question (2) and Question 5a. … (Question 5). … Key Question 2 and Question 5a.