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  1. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-screening-for-familial-hypercholesterolemia/lipid-disorders-in-children-screening-july-2016
    August 09, 2016 - Main Outcomes and Measures: Myocardial infarction and ischemic stroke in adulthood; lipid concentrations … In general, a good-quality study met all quality criteria. … Outcomes No direct evidence supports a link between lipid concentrations or measures of atherosclerosis … , 66 Reaching agreement on acceptable surrogate end points, such as CIMT and other atherosclerosis measures … AHRQ had no role in study selection, quality assessment, or synthesis.
  2. www.uspreventiveservicestaskforce.org/home/getfilebytoken/HZGtYqL_8u57Gkc6YFctmT
    August 21, 2018 - MAIN OUTCOMES AND MEASURES Lifetime number of tests, colposcopies, disease detection, false-positive … professional organizations.4 Although empirical studies such as randomized clinical trials pro- vide high-quality … These measures were calcu- lated as the cumulative number of events or time spent in the dif- ferent … funded under contract HHSA-290-2012-00015-I, Task Order 6, from the Agency for Healthcare Research and Quality … Rockville, MD: Agency for Healthcare Research and Quality; 2017.
  3. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/depression-screening-2002
    May 07, 2002 - The wide variation in interventions tested, outcome measures used, and timing of followup assessments … between differences in outcomes and patient and provider characteristics, use of particular outcome measures … , varying duration of followup, or trial quality. … researchers chose not to combine the results in a meta-analysis because the studies used different outcome measures … Rockville, MD: Agency for Healthcare Research and Quality; 2002. 10.
  4. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/prostate-cancer-screening
    May 08, 2018 - Main Outcomes and Measures: Prostate cancer and all-cause mortality; false-positive screening results … measures compared with conservative management. … , 70-73 , 75 , 77 , 78 , 86 suggest no substantive adverse effect of radiation therapy on general measures … Radical prostatectomy not associated with decrement in generic measures of quality of life vs conservative … Radiation therapy not associated with decrement in generic measures of quality of life vs conservative
  5. www.uspreventiveservicestaskforce.org/home/getfilebytoken/3XUeA-_n8KhYeS95ohoo2_
    August 03, 2020 - Studies were excluded if they did not measure clinical outcomes in ei¬ ther the mother or newborn. … Birth weights below the 25th percentile oc¬ curred in 35% of women who responded to therapy (hematocrit … Trials Most clinical trials of iron supplemen¬ tation have used changes in hématologie indexes as the measure … One of the first trials to assess health outcomes used subjective measures. … CONCLUSION The quality of the evidence in support of the causal chain outlined at the be¬ ginning of
  6. www.uspreventiveservicestaskforce.org/home/getfilebytoken/h-w99jVsodSL33kV2h2_qW
    April 17, 2018 - Exercise Interventions The USPSTF found 5 good-quality and 16 fair-quality studies (n = 7297) reporting … Vitamin D Supplementation Four good-quality and 3 fair-quality studies (n = 7531) reported on the effect … living showed no benefit, but these studies used different scales, and few were adequately powered to … Potential Harms of Preventive Measures Evidence on harms was reported in a subset of trials reporting … A pilot study to explore the predictive validity of 4 measures of falls risk in frail elderly patients
  7. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/healthy-weight-and-weight-gain-during-pregnancy-behavioral-counseling-interventions
    May 25, 2021 - Main Outcomes and Measures: Gestational weight–related outcomes; maternal and infant morbidity and mortality … If necessary, mean weight change was calculated based on reported baseline and follow-up weights; when … 67 , 69-71 , 73 , 77 , 79 , 80 , 82 Gestational hypertension was defined as persistent or repeated measures … by study quality. … Mixed effects reported for rates of depression and anxiety as measured by various, validated symptom scales
  8. www.uspreventiveservicestaskforce.org/home/getfilebytoken/aHH-PY8unwJXW5NqJhRUz6
    May 01, 2014 - Information from a clinical evaluation also has been proposed, as well as qualitative or quantitative measure … associated with dental caries in young children include lack of access to dental care; inadequate preventive measures … The evidence is limited in that measures of early childhood fluoride exposure were based on parental … Systemic fluoride also provides some measure of topical effects, as it is found in the saliva and bathes … Rockville, MD: Agency for Healthcare Research and Quality; 2014.
  9. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan151/lipid-disorders-in-children-screening-july-2016
    January 15, 2015 - They should not be construed as an official position of the Agency for Healthcare Research and Quality … : RCTs, CCTs, cohort studies, systematic reviews, registry studies, long-term trial followup, high-quality … : RCTs, CCTs, cohort studies, systematic reviews, registry studies, long-term trial followup, high-quality … : RCTs, CCTs, systematic reviews, cohort studies, registry studies, long-term trial followup, high-quality … case-control studies All KQs: Studies rated as poor quality KQs 1–3, 5, 6, 8: Qualitative
  10. www.uspreventiveservicestaskforce.org/home/getfilebytoken/nMb54adBfgajp8dG87kPcw
    April 17, 2018 - MAIN OUTCOMES AND MEASURES Number of falls (number of unexpected events in which a person comes to rest … .78,79 A 2016 systematic review of tools for assessing risk of falls concluded that no single test or measure … included in the review (56 measures in- cluding history questions, self-report measures, and performance … - based measures) was an accurate diagnostic tool.80 Given the complex set of factors contributing to … falls in older in- dividuals, combining measures may help to accurately predict fu- ture falls; however
  11. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
    September 28, 2021 - Main Outcomes and Measures: Diagnosis of preeclampsia; adverse pregnancy health outcomes and complications … conducted among pregnant persons selected based on the presence of clinical risk factors or physical measures … A common reporting measure of adherence in the trials was the number of women who were found to be taking … determine whether the use of a risk prediction model that requires multiple historical and physical measuresQuality : Study was poor quality.
  12. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-cancer-screening-2002
    September 03, 2002 - originally conducted, the Swedish trials had important flaws related to measurement of the primary outcome measure … , autopsies, registries), and use of independent blinded review of the cause of death are important measures … credible interval for a given length of follow-up . 11 The purpose of this analysis was to use repeated measures … Results of intermediate measures from a population-based, randomized trial of mammographic screening … The epidemiology of mass breast cancer screening—a plea for a valid measure of benefit.
  13. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Q__nXYQ7cWPBuwvt27sQ42
    July 01, 2013 - Two reviewers independently assessed methodological quality. … Data Extraction and Quality Assessment Two reviewers independently assessed the method- ological quality … Sensitivity and specificity are measures of test accu- racy. … Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic … Comparison of accuracy measures of two screening tests for gestational diabetes mellitus.
  14. www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/Harris2001.pdf
    January 01, 2001 - 5 for interme- diate or health outcomes, respectively), and the associ- ation between intermediate measures … measured by a DNA probe) are often used in studies as indicators of efficacy; health out- comes are measures … If high-quality evi- dence is available, the topic teams may exclude lower- quality studies. … Conversely, if higher-quality evidence is lacking, the teams may examine lower-quality evidence. … Beware of surrogate outcome measures. Int J Tech Assess Health Care 1996;12:238–46. 20.
  15. www.uspreventiveservicestaskforce.org/uspstf/document/update-on-the-methods-of-the-us-preventive-services-task-force-estimating-certainty-and-magnitude-of-net-bene%EF%AC%81t/carotid-artery-stenosis-screening-december-2007
    December 15, 2007 - They should not be construed as an official position of the Agency for Healthcare Research and Quality … Individual studies will continue to be judged as being of "good," "fair," or "poor" quality. … Evidence may be considered convincing when derived from several high-quality studies with consistent, … This last category refers to preventive measures that, if implemented in the general primary care population … To what extent are the existing studies of high quality? (i.e., what is the internal validity?)
  16. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breastfeeding-primary-care-interventions
    April 11, 2025 - Main Outcomes and Measures: Child and maternal health outcomes, prevalence, and duration of any and … Data Extraction and Quality Assessment Two reviewers independently assessed the methodological quality … 1 101 of the 90 included trials (N = 49,597) reported the effects of an intervention on at least 1 measure … “problems” between those in the intervention vs usual care groups in 22 studies that reported these measuresQuality: Study was rated as poor quality.
  17. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Jwn6dWRHvK3C9oJCV6hLKc
    September 05, 2017 - MAIN OUTCOMES AND MEASURES Visual acuity, amblyopia, school performance, functioning, quality of life … To provide a consistent metric for visual acuity outcome measures, results were converted to loga­ rithm … of the minimal angle of resolution (logMAR) measurements using established conversion charts.31 Measures … visual acuity are generally reported as Snellen (eg, 20/20, 20/25, 20/30, 20/40, 20/50) or logMAR scales … Improving the reliability of visual acuity measures in young children.
  18. www.uspreventiveservicestaskforce.org/home/getfilebytoken/R_cAa3AjFGQ2np_aQnzQGA
    February 11, 2025 - MAIN OUTCOMES AND MEASURES Hip, clinical vertebral, major osteoporotic, and total fractures; mortality … rated the included primary studies as poor quality. … Three RCTs were good quality159,162,174,176,177,179; the rest were fair quality. … and hip fracture) 4 Articles from 4 unique cohorts41,63,91,100 (18 145) Inconsistent calibration measures … AHRQ had no role in study selection, quality assessment, or synthesis.
  19. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary14/bladder-cancer-in-adults-screening
    October 15, 2010 - Primary Funding Source:  Agency for Healthcare Research and Quality. … We resolved discrepancies in quality ratings by discussion and consensus. … Agency for Healthcare Research and Quality.) … Rockville, MD: Agency for Healthcare Research and Quality; 2004. … Outcomes Includes morbidity, mortality, and health-related quality of life.
  20. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-primary-care-screening-for-and-treatment-of/depression-in-adults-screening
    January 26, 2016 - Main Outcomes and Measures: Depression remission, prevalence, symptoms, and related measures of depression … recovery or response; sensitivity and specificity of selected screening measures to detect depression … Results were similar for 2 other continuous measures of depression symptom severity, but this trial did … The use of rating scales to identify post-natal depression. … Validation of two postpartum depression screening scales with a sample of First Nations and Métis women

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