-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_research-protocol.pdf
September 22, 2014 - However, because these outcomes can be difficult to measure directly, other
outcomes that occur intermediately … Therefore it will
be important to capture how each study defines and measures appropriateness and consider … While this is not a direct measure of
the primary outcomes, we will report these as indirect measures … of the strategy, such as increased time burden on clinicians, sustainability of
intervention (e.g. measures … rated good in quality; the remainder will be rated fair in quality.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-update_research-protocol.pdf
December 04, 2015 - For continuous outcomes measures,
we will extract (by arm) the mean baseline and endpoint or change … scores, standard deviations
(SD) or other measure of variability, and number analyzed. … quality, and 3 or fewer stars to indicate
poor quality. … For quality of life and
other continuous patient/parent/clinician-reported measures, we will use an … (e.g.,
aggression scales or subscales) if the scales are considered to measure the same construct;
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_executive.pdf
November 01, 2012 - psoriasis vulgaris, often appears as
well-demarcated, erythematous plaques
covered with silvery white scales … Therefore, we qualitatively
evaluated the data and reported native measures of effect
5
that were … all were based on low strength
of evidence.13,23 HRQoL was measured using both the
DLQI and EQ-5D scales … Three scales were used to measure
HRQoL in this trial—DLQI, EQ-5D, and SF-36 MCS
(mental) and PCS ( … The validity and
responsiveness of three quality of life measures in the assessment
of psoriasis patients
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/glaucoma-treatment_research-protocol.pdf
November 16, 2010 - Background and Objectives for the Systematic Review
The Agency for Healthcare Research and Quality … www.effectivehealthcare.ahrq.gov/�
Source: www.effectivehealthcare.ahrq.gov
Published Online: November 16, 2010
Measures … Standardized mean
differences will be calculated if continuous outcomes are measured by using different scales … Grading quality of evidence and strength of recommendations.
BMJ 2004;328:1490.
14. … Agency for Healthcare Research and Quality.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-update_research-protocol.pdf
August 18, 2016 - , the Conner scales, and the SNAP-IV rating
scales.21-23 Monitoring also includes assessment of any … Final Outcomes: Outcomes associated with having ADHD in childhood primarily are based on
measures of … the diagnosis in the primary care setting and the diagnosis by the specialist will be
converted into measures … Labeling will be any measure of stigma following diagnosis comparing
those with and without ADHD. … o Risk of missed condition that can appear as ADHD
(i.e., misdiagnosis)
• Labeling will be any measure
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
May 24, 2010 - Do performance measures vary with sample characteristics? … environmental cleaning, handcleansing, patient isolation, prebiotics or probiotics used as
preventive measure … Prevention: placebo or active controls for probiotics used as preventive measure. … CDAD mortality rates
Prevention Intermediate Process Measures/Outcomes
1. … Measures to control and prevent Clostridium difficile
infection.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
March 01, 2018 - What were the differences, if any, in pre-specified outcome measures, statistical
plan and size of the … completed studies which were in both:
What were the differences, if any, in pre-specified outcome measures … , 9, 14
For two studies,9, 14 the ClinicalTrials.gov record and the publication reported different measures … All five of the studies listed
quality of life as an outcome measure. … Topiramate and physiologic measures of
nerve function in polyneuropathy.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd_executive.pdf
September 01, 2011 - Similar considerations apply to the assessment of
outcomes, which included measures of formal or
informal … antireflux surgery also demonstrated
improvement (in some cases statistically significant) on
reflux symptom scales … No significant differences
in heartburn score, SF-36 and Global REFLUX-QUAL
scores, 24-hour pH study measures … is likely due to
the considerable heterogeneity in the study populations,
interventions, and outcome measures … in patients with
exercise-induced asthma compared to a placebo, but not
QoL or pulmonary function measures
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pelvic-pain_executive.pdf
January 01, 2012 - Quality assessment. … We saw
this variation in (1) definition of pelvic pain, (2) patient
populations, (3) outcome measures … , (4) interventions,
(5) timing of outcome measures and participant
followup, and (6) comparators. … Studies differed considerably in
terms of study populations, interventions, and outcome
measures. … approaches to promote clear delineation of patient
populations in CPP research
• Standardizing outcome measures
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-adolescents_research-protocol.pdf
March 29, 2011 - Outcomes
• Respondents noted that outcome measures are variable across ASD research studies and … Residential supports
• Comparators:
o Placebo, usual care, or active control
• Outcome measures … We will identify specific outcome measures to
extract in consultation with the TEP and based on our … Pre-specifying each measure to extract is not feasible given
the large number of assessment tools/measures … Assessment of Methodological Quality of Individual Studies
We will assess study quality by using
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy-disposition-170415.pdf
January 17, 2017 - Rockville, MD: Agency for Healthcare Research and Quality. January 2017. … its contents, and do not necessarily represent
the views of the Agency for Healthcare Research and Quality … The multitude of outcome measures are
defined. … Our key outcomes of interest included AHI,
desaturation nadir, and measures of sleep
quality including … under KQ1 I would like to read something
about whether the AHI versus symptom relief is a
better measure
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
February 01, 2013 - The outcome measures included, and inclusion of non-English
language papers account for at least some … that are notoriously
characterized by variability in outcome measurement methods and a multitude of scales … choose
to restrict to specific measurement methods (i.e., only including studies that used measurement
scales … Because the study is
registered at the beginning of the study, the intended primary outcome measures … Disagreements in meta-analyses using
outcomes measured on continuous or rating
scales: observer agreement
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-nonsurgical-therapies_research-protocol.pdf
February 22, 2012 - data analysis, including:
○ Statistical analyses (statistical test/estimation results)
○ Summary measures … ○ Sample variability measures
○ Precision of estimate
○ p values
• Regression modeling techniques … ○ Were outcome measures clearly valid, reliable, and equally applied to treatment groups? … and elsewhere.27, 34, 35
When appropriate (e.g., similar instruments used or standardized effect measures … relevant
and interpretable), outcome measures will be pooled according to AHRQ guidance, and
synthesized
-
effectivehealthcare.ahrq.gov/sites/default/files/grading.ppt
January 01, 2013 - used by the Evidence-based Practice Centers (EPCs) to grade strength of evidence is based in large measure … reviewers can assess consistency on the basis of similarity of populations, interventions, and outcome measures … meta-analysis is appropriate, EPC reviewers can evaluate consistency by using statistical tests and measures … of life, or effects on laboratory measures or other surrogate variables)
Each major harm (ranging … of life, or effects on laboratory measures or other surrogate variables) and each major harm (ranging
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_executive.pdf
September 01, 2009 - two options in terms of clinical events (e.g.,
myocardial infarction, stroke, or death), surrogate
measures … Methodological Quality Assessment
Study quality of RCTs was assessed with the Jadad
scale, and of nonrandomized … Most of the
evidence originates from short-term studies aimed at
biochemical measures and therefore is … Measures of atherosclerosis
Carotid intimal media thickness (IMT) can be measured
by ultrasound and … • Measures of adherence and persistence are
affected by the duration of the study period, and
thus
-
effectivehealthcare.ahrq.gov/sites/default/files/hip-fracture-pain.ppt
May 01, 2011 - References:
Agency for Healthcare Research and Quality. … Numerical scales show a linear correlation with VAS results. … Two methods are commonly used in clinical studies to measure the intensity of pain. … In using numerical scales, the patient is instructed to indicate a number, for example between 0 and … Numerical scales and the VAS show a linear correlation.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hip-fracture-pain.ppt
May 01, 2011 - References:
Agency for Healthcare Research and Quality. … Numerical scales show a linear correlation with VAS results. … Two methods are commonly used in clinical studies to measure the intensity of pain. … In using numerical scales, the patient is instructed to indicate a number, for example between 0 and … Numerical scales and the VAS show a linear correlation.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
September 23, 2016 - of life (using validated scales
and including mental and physical health)
§ Ability to maintain … Re-hospitalization was not included because it is considered a flawed outcome
measure for two reasons … the intervention, e.g.:
• New or worsening symptoms (e.g., anxiety or depression)
using validated scales … of life (using validated
scales and including mental and physical health)
• Ability to maintain … a priori, but poor-quality studies will be considered to be less reliable than
higher quality studies
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_executive.pdf
March 01, 2013 - However it is crucial to
note that direct measures of ovulation are not employed
in most available … function as reported by sexual function measures, general measures of sexual activity, frequency
and … Quality (Risk of Bias) Assessment
We assessed quality of RCTs using the Cochrane
Collaboration Risk … For
regularity of bleeding no two measures of outcome were
the same. … Two studies were classified as good
6
quality,51,60 two studies as fair quality,55,63 and six
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_clinician.pdf
August 01, 2016 - The other review
assessed the evidence regarding the comparative efficacy of measures to prevent CIN … In 2013, the National Kidney Foundation–
Kidney Disease Outcomes Quality Initiative recommended
the … strength of a body of evidence when comparing medical interventions—Agency for Healthcare Research and Quality … Evidence-based
Practice Center under Contract 290-2012-00007-I for the
Agency for Healthcare Research and Quality … published in December 2015) and
Contrast-Induced Nephropathy: Comparative Effectiveness of
Preventive Measures