-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-adherence_research-protocol.pdf
September 13, 2011 - others may include the frequency and timing of administrating each dose
as components in defining measures … Comparators:
• Standard care and/or other HCV treatment adherence interventions
Outcomes measures … • Definitions and measure of adherence: we will document the adherence definitions used
in each study … regimen
adherence (e.g., followup visits, laboratory tests); cut-off value for defining adherence;
measure … We
will document the results reported by the authors, including effect measures, point
estimates, 95%
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_executive.pdf
April 01, 2012 - In the case of UI, it is unclear whether
physiological measures represent a gold standard against
which … other measures can be compared, or whether they
should be viewed as information that may predict key … Hence, we may be more
interested in levels of agreement between physiological
measures and patient … We chose the random-effects inverse variance
weights model to incorporate in the pooled analysis
differences … Validated tools to measure UI treatment success based
on meaningful changes in symptoms and quality
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_disposition-comments.pdf
April 25, 2013 - They are both tests that measure the same thing. … These
are not of publication quality. … KQ1: Most outcome measures for echocardiography are good. … KQ2: Outcome measure in table 16(Page 64) are appropriate Thank you for your comment. … Additional biomarkers or combinations of echo measures should
be evaluated.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_research-protocol.pdf
March 13, 2012 - New assays that measure
RNA to detect tumor cells are also beyond the scope of this report. … The FDA
addresses the safety and effectiveness of diagnostic tests and the quality of the design
and … Analytic validity
relates to the reliability and validity of the test itself, that is, does it measure … Rockville, MD: Agency for
Healthcare Research and Quality; January 2008. … Analytic validity:
How accurately and reliably the test measures the genotype of interest.14
Clinical
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_executive.pdf
April 01, 2013 - We
used random-effects models to estimate pooled effects.19
For continuous outcomes (e.g., scales for … When multiple scales were combined in
one meta-analysis, we used the standardized mean
difference … Adverse events were often not collected using standardized
measures, and methods for systematically … of PTSD diagnosis
(frequently not reported) in addition to measures of PTSD
symptoms (more commonly … Future studies could include longer followup
of subjects, validated measures of adverse events and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_surveillance.pdf
October 01, 2012 - risperidone and
aripiprazole each have
at least two
RCTs demonstrating
improvement in a
parent-reported measure … A parent reported
hyperactivity and
noncompliance measure
also showed significant
improvement. … All studies of sensory
integration and music
therapy were of poor
quality, and two fair-
quality studies … Do Not Know
parent-reported measure of challenging
behavior. … A parent reported hyperactivity
and noncompliance measure also showed
significant improvement.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-update_research-protocol.pdf
September 20, 2013 - Prespecifying each individual measure to extract is not feasible, given the large number of
assessment … tools/measures used in the ASD literature; however, we anticipate that we will focus
on well-established … , validated outcome measures or techniques that incorporate measures of
agreement (e.g., measures to … intervention approach, and dosage; assessment characteristics including
instruments used and fidelity measures … We required at least one good-quality study for
moderate SOE and two good-quality studies for high SOE
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
January 28, 2019 - adequately treated if it is not appropriately assessed, a careful
evaluation of validated tools to measure … Current guidelines7 for the management of prehospital trauma pain recommend specific
pain scales, broken … absence of a gold standard
assessment tool.8 Of particular interest is the evidence for use of these scales … , and the results of
each outcome, including measures of variability. … The
arcsine difference as a measure of treatment effect in meta-analysis with zero cells.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_disposition-comments.pdf
November 27, 2012 - The definitions for the outcome measures are appropriate. … Key questions- lots of acronyms for measures. … For
example a brief description of each scale chosen, and some reasoning why
these scales were chosen … literature, and if there are
meaningful clinical differences (MCIDs) for what level of improvement in
scales … Within the
glossary we define the outcomes, provide
the standard scale sued to measure the
outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_executive.pdf
February 01, 2014 - Biochemical validation of smoking
status includes measures of cotinine from saliva, urine, or
serum … Although these measures do not verify continuous
abstinence, they are accepted standards for evaluating … One study is of good
quality, three of fair quality, and nine of poor quality. … than the null
for the intervention increasing smoking cessation, include
feedback about biologic measures … A sustained measure of smoking abstinence, as opposed
to a point prevalence measure, would be ideal
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_disposition-comments.pdf
August 23, 2013 - of life measures as compared with active controls. … However, both of these scales are considered to
be reliable and valid and are widely used. … Subjective measures of loudness were retained
as eligible outcome measures because they
were felt to … for any
studies that used the terms ‘discomfort’,
‘annoyance’ or ‘distress’ to describe an outcome
measure … The primary reasons they were
excluded is that the studies did not present a
measure of variance around
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-brain-injury-surveillance-160902.pdf
January 30, 2014 - BDI"II=Beck$Depression$Inventory"2S$CT=Computed$TomographyS$GCS=Glasgow$Coma$ScaleS$MDD=Major$Depressive … HAM"D=Hamilton$Depression$Rating$ScaleS$TBI=Traumatic$Brain$Injury$$
((
(
Abstracts(from(Relevant( … $MEASURES:$Participants$completed$the$Structured$Clinical$
Interview$for$DSM"IV$and$self"report$measures … BDI"II=Beck$Depression$Inventory"2S$CT=Computed$TomographyS$GCS=Glasgow$Coma$ScaleS$MDD=Major$Depressive … $Evaluation$of$the$patient$generated$index$as$a$measure$of$quality"of"life$in$
people$with$severe$traumatic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-209-evidence-summary-non-pharma-chronic-pain.pdf
June 01, 2018 - Quality Assessment of Individual Studies
Study quality was independently assessed by two
investigators … functional outcomes
roughly corresponds to reported minimum clinically
important differences for the measure … percent considered
good quality. … trial;
mean difference -1.38 to -1.59 on the affective and
-0.28 to -0.71 on the sensory dimension [scales … Outcomes measures Lack of consistency in types outcomes measures
used for function and pain across trials
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/peripheral-artery-disease-treatment_research-protocol.pdf
January 31, 2013 - compared exercise training to usual
care.22 It found statistically significant improvements in walking measures … imperative to compare the efficacy of exercise training and endovascular
revascularization on walking measures … Inclusion of symptomatic patients with atypical leg symptoms in KQs 1 and 2
• Expansion of outcome measures … criteria for quality and critical appraisal,
and (3) arrive at a summary judgment of the study’s quality … data is in the form of
effect sizes due to
multiple treatment
arms and/or the use
of different measures
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay-future_research.pdf
September 01, 2012 - It detects low
concentrations of FLCs and can measure the ratio of kappa chains to lambda chains. … Outcomes Measures of diagnostic accuracy (e.g.,
sensitivity, specificity, or predictive
value) in … Dependent on the percentage of
respondents, quality of participation and
responses and the quality … Three studies (all quality C) were conducted in patients with AL
amyloidosis15,26, 28 and 8 (3 quality … Dependent on the percentage of
respondents, quality of participation and responses and the quality
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
September 25, 2013 - Rockville, MD:
Agency for Healthcare Research and Quality; September 2013. … Peer Reviewer #6 General
Comments
Quality of the Report: Good
Number of Hours Spent to Review the … Definitions, outcome measures
and statistical methods are appropriate. … The outcome measures used for this topic are quite
complicated with several of them relying on epidemiological … identifies 40 studies that examined the
association of genotype results with platelet reactivity
measures
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/aggression_research-protocol.pdf
October 05, 2015 - measure, particularly for psychiatric
patients in hospital settings.49 The International Quality Indicator … scales)!
-! KQs!1a!and!1c!only:!Reduced!use!of!
seclusion!or!restraints!(decreased!
rate,! … Methodological issues in
monitoring the use of coercive measures. … Hospital-Based Inpatient Psychiatric Services (HBIPS)-2: Joint Commission
National Quality Core measure … HBIPS-3: Joint Commission National Quality Core measure for seclusion
endorsed by the National Quality
-
effectivehealthcare.ahrq.gov/sites/default/files/s38.pdf
October 01, 2007 - ORIGINAL ARTICLE
Design of Cluster-Randomized Trials of Quality
Improvement Interventions Aimed at Medical … Thus, measures of agreement
in treatments received by patients of different providers
within a practice … One simple measure of
sharing would be the percent of potentially eligible patients
who see multiple … More sophisti-
cated measures of clustering within practices could use mul-
tilevel models to quantify … intervention or control
group in blocks of 4 within the 12 strata formed by the
cross-classification of these measures
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pain-chronic_research-protocol.pdf
July 28, 2010 - eliminating pain to
managing pain to an extent that the patient’s independence is restored and overall quality … study inclusion and exclusion criteria), duration of
patient followup, outcomes assessed (specific measures … Outcomes Assessed (Measures and Timing) and Patient Characteristic Interacted with
Treatment
D. … Outcomes Assessed (Measures and Timing) and Patient Characteristics Interacted with Therapy
Study … Outcome 1
(measure & timing)
Outcome 2
(measure & timing)
Outcome 3
(measure & timing)
Patient
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
October 14, 2011 - association between PCA3 mRNA levels and prostate cancer
led to the development of a urinary assay to measure … Were outcome measures clearly valid, reliable, and equally applied to treatment groups? … Did each meta-analysis include the model used; results with
confidence intervals; homogeneity measures … Did each meta-analysis include the model used; results with
confidence intervals; homogeneity measures … Prostate-specific antigen velocity (PSA velocity) — a measure of the rapidity of change in a
man’s PSA