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61. Prostate-Cancer-Therapies-Update Consumer (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_consumer.pdf
    January 01, 2016 - � PSA blood test: This blood test tells how much PSA (a protein made by the prostate gland) is in … – A high PSA level does not always mean a man has prostate cancer. … This growth, and other health conditions, can cause a high PSA level in men who do not have prostate … Your doctor can use your PSA level, Gleason score, and tumor score (T-score) to determine your risk … The cancer is found from a biopsy done after a man has a high PSA level or has surgery for problems

62. Tx-For-Localized-Prostate-Cancer Surveillanceassesment 20120614 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/tx-for-localized-prostate-cancer_surveillanceassesment_20120614.pdf
    May 01, 2012 - However, a subgroup analysis suggested that men with high-risk features (PSA > 10, and intermediate … levels and Gleason histologic score (PSA >10 ng/ml or Gleason >6). … In men with PSA >10, radical prostatectomy reduced overall mortality (HR = 0.36, p=0.03). … In men with PSA >10, radical prostatectomy reduced overall mortality (HR = 0.36, p=0.03). … levels and Gleason histologic score (PSA >10 ng/ml or Gleason >6).

63. Tx-For-Localized-Prostate-Cancer Surveillanceassesment 20120614 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/tx-for-localized-prostate-cancer_surveillanceassesment_20120614.pdf
    May 01, 2012 - However, a subgroup analysis suggested that men with high-risk features (PSA > 10, and intermediate … levels and Gleason histologic score (PSA >10 ng/ml or Gleason >6). … In men with PSA >10, radical prostatectomy reduced overall mortality (HR = 0.36, p=0.03). … In men with PSA >10, radical prostatectomy reduced overall mortality (HR = 0.36, p=0.03). … levels and Gleason histologic score (PSA >10 ng/ml or Gleason >6).

64. Clinical Summary: Screening for Prostate Cancer (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/D2Y537H2WCXLrT82Z2M46u
    April 30, 2018 - Screening for prostate cancer begins with a test that measures the amount of prostate-specific antigen (PSA … An elevated PSA level may be caused by prostate cancer but can also be caused by other conditions, including … Men with a positive PSA test result may undergo a transrectal ultrasound-guided core-needle biopsy of

65. Therapies for Clinically Localized Prostate Cancer (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_clinician.pdf
    January 01, 2016 - convened in 2011 recommended that AS—a strategy with curative intent that involves regular monitoring of PSA … and then intervening to manage them.3 WW does not include active monitoring such as performing a PSA … Presenting symptoms, a physical examination, a prostate- specific antigen (PSA) test, and a biopsy may … by factors such as patient age and health at the time of diagnosis, life expectancy, tumor stage, PSA … Prostate cancer incidence and PSA testing patterns in relation to USPSTF screening recommendations.

66. U.S. Preventive Services Task Force Issues Final Recommendation on Screening for Prostate Cancer (pdf file)
    www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/file/supporting_documents/prostate-cancer-news-bulletin-updated-102018.pdf
    May 08, 2018 - patients with important new information about the benefits and harms of prostate-specific antigen (PSA … the Task Force recommends that men ages 55 to 69 make an individual decision about whether to get PSA-based … The PSA test measures the amount of prostate-specific antigen, a type of protein, in a man’s blood. … An elevated PSA level may be caused by prostate cancer, but it could also be caused by other conditions … PSA-based screening and the prostate biopsies used to follow-up on high PSA levels cannot tell for sure

67. Comparative Effectiveness of Therapies for Clinically Localized Prostate Cancer: An Update of a 2008 Comparative Effectiveness Review | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/prostate-cancer-therapies-update/research-protocol
    March 29, 2013 - The PSA test is used to measure blood levels of PSA, a protein produced by the prostate gland. 4 Elevated … X=unknown I T1a–c N0 M0 PSA<10 Gleason ≤6   T2a N0 M0 PSA<10 Gleason ≤6   … T1–2a N0 M0 PSA X Gleason X IIA T1a–c N0 M0 PSA<20 Gleason 7   T1a–c N0 … M0 PSA≥10<20 Gleason ≤6   T2a N0 M0 PSA≥10<20 Gleason ≤6   T2a N0 M0 PSA<20 … T2c N0 M0 Any PSA Any Gleason   T1–2 N0 M0 PSA ≥20 Any Gleason   T1–2 N0

68. Prostate-Cancer-Therapies-Update Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_research-protocol.pdf
    April 01, 2013 - The PSA test is used to measure blood levels of PSA, a protein produced by the prostate gland.4 Elevated … Anatomic and prognostic staging Stage Group T* N M PSA Gleason I T1a–c N0 M0 PSA<10 Gleason ≤6 T2a … N0 M0 PSA<10 Gleason ≤6 T1–2a N0 M0 PSA X Gleason X IIA T1a–c N0 M0 PSA<20 Gleason 7 T1a–c N0 M0 … PSA≥10<20 Gleason ≤6 T2a N0 M0 PSA≥10<20 Gleason ≤6 T2a N0 M0 PSA<20 Gleason 7 T2b N0 M0 PSA<20 … Gleason ≤7 IIB T2b N0 M0 PSA X Gleason X T2c N0 M0 Any PSA Any Gleason T1–2 N0 M0 PSA≥20 Any Gleason

69. STATISTICAL BRIEF #82: Access to Care and Use of Preventive Services, 2002: Estimates for the U.S. Civilian Noninstitutionalized Population, Age 18 to 64
    meps.ahrq.gov/data_files/publications/st82/draft/stat82.shtml
    June 01, 2005 - with private health insurance were more likely (58.7 percent) to obtain a prostate-specific antigen (PSA … In comparison, men with no health insurance coverage were the least likely to have a PSA test. … In 2002, only 22.2 percent of uninsured men had a PSA test within the last year, and 28.5 percent had … Among men with only public health insurance, 33.9 percent had a PSA test within the last year and 45.4 … Mammogram screening, Pap test, and PSA test were included in this analysis.

70. STATISTICAL BRIEF #82: Access to Care and Use of Preventive Services, 2002: Estimates for the U.S. Civilian Noninstitutionalized Population, Age 18 to 64
    meps.ahrq.gov/data_files/publications/st82/stat82.shtml
    June 01, 2005 - with private health insurance were more likely (58.7 percent) to obtain a prostate-specific antigen (PSA … In comparison, men with no health insurance coverage were the least likely to have a PSA test. … In 2002, only 22.2 percent of uninsured men had a PSA test within the last year, and 28.5 percent had … Among men with only public health insurance, 33.9 percent had a PSA test within the last year and 45.4 … Mammogram screening, Pap test, and PSA test were included in this analysis.

71. Sb82
    meps.ahrq.gov/data_files/publications/st82/sb82.xml
    June 01, 2005 - with private health insurance were more likely (58.7 percent) to obtain a prostate-specific antigen (PSA … In comparison, men with no health insurance coverage were the least likely to have a PSA test. … In 2002, only 22.2 percent of uninsured men had a PSA test within the last year, and 28.5 percent had … Among men with only public health insurance, 33.9 percent had a PSA test within the last year and 45.4 … Mammogram screening, Pap test, and PSA test were included in this analysis.

72. Statistical Brief #82: Access to Care and Use of Preventive Services, 2002: Estimates for the U.S. Civilian Noninstitutionalized Population, Age 18 to 64 (pdf file)
    meps.ahrq.gov/data_files/publications/st82/stat82.pdf
    June 01, 2005 - private health insurance were more likely (58.7 percent) to obtain a prostate-specific antigen (PSA … to 64 covered by private health insurance were more likely to obtain a prostate-specific antigen (PSA … In comparison, men with no health insurance coverage were the least likely to have a PSA test. … In 2002, only 22.2 percent of uninsured men had a PSA test within the last year, and 28.5 percent had … Mammogram screening, Pap test, and PSA test were included in this analysis.

73. An Evidence Review of Active Surveillance in Men with Localized Prostate Cancer | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/prostate-cancer-surveillance/research
    December 06, 2011 - Increased diagnosis of early-stage prostate cancer due to prostate-specific antigen (PSA) testing, led … Currently, patients are diagnosed with earlier stage and lower risk prostate cancers compared to the pre-PSA … different monitoring protocols, all with different combinations of periodic digital rectal examination, PSA … included older age, presence of comorbidities, lower Gleason score, lower tumor stage, lower diagnostic PSA

74. Measures of Inefficiency | Agency for Healthcare Research and Quality
    ce.effectivehealthcare.ahrq.gov/research/findings/nhqrdr/chartbooks/careaffordability/measures3.html
    June 01, 2018 - Services Task Force recommended against screening men age 75 and over with prostate-specific antigen (PSA … Overall Rate: In 2014, 21.1% of men age 40 and over reported a PSA test in the past year (data not shown … Groups With Disparities: In 2014, men ages 40-54 were less likely to receive a PSA test in the past … Among men ages 40-54, Asians were less likely than Whites to receive PSA testing and Blacks were more … Among men age 75 and over, AI/ANs were less likely than Whites to receive PSA testing.

75. Therapies for Clinically Localized Prostate Cancer | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/prostate-cancer-therapies-update/clinician
    January 21, 2016 - Presenting symptoms, a physical examination, a prostate-specific antigen (PSA) test, and a biopsy may … convened in 2011 recommended that AS—a strategy with curative intent that involves regular monitoring of PSA … and then intervening to manage them. 3 WW does not include active monitoring such as performing a PSA … Physicians might take into consideration age, general health status, stage of tumor, PSA level, Gleason … Prostate cancer incidence and PSA testing patterns in relation to USPSTF screening recommendations.

76. Prostate-Specific Antigen–Based Screening for Prostate Cancer: Evidence Report and Systematic Review for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/b-rsH7WPpNC3uL9NeoXBfF
    May 08, 2018 - OBJECTIVE To systematically review evidence on prostate-specific antigen (PSA)–based prostate cancer … Randomization to PSA screening was not associated with reduced risk of prostate cancer mortality in either … 2 What are the harms of PSA-based screening for prostate cancer and diagnostic follow-up? a. … Effectiveness of PSA-Based Screening Key Question 1. … What are the harms of PSA-based screening for pros- tate cancer and diagnostic follow-up?

77. Arthritis and Nontraumatic Joint Disease (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - About 50% of patients with PsA have the HLA-B27 allele. … The main symptoms of PsA are joint pain, stiffness, and swelling that can affect any joint. … Secukinumab (Cosentyx) for Treatment of Psoriatic Arthritis  Key Facts: Current treatments for PsA … By blocking the effects of IL-17A–localized autoimmune reactions, PsA symptoms may be limited while … Four phase III trials on secukinumab for treating PsA are ongoing.

78. Localized Prostate Cancer | Effective Health Care
    effectivehealthcare.ahrq.gov/decision-aids/prostate-cancer/09.html
    June 08, 2018 - Your PSA number, Gleason Score, and T stage will help you and your doctor choose the next best step in … If you know it, enter your PSA number here:    If you know it, enter your Gleason Score here:   

79. Tratamiento del cáncer de próstata localizado: Revisión de la investigación para adultos (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_espanol.pdf
    November 01, 2016 - � Examen de sangre para antígeno prostático específico (PSA, en inglés): Este análisis de sangre … indica cuánto PSA (una proteína elaborada por la próstata) circula en la sangre. … En muchos casos de cáncer de próstata, el nivel de PSA es mayor de lo normal o ha aumentado con el … ☐ Un nivel alto de PSA no siempre significa que el hombre tenga cáncer de próstata. … Este agrandamiento y otros problemas de salud pueden causar un nivel alto de PSA en hombres que no

80. Tratamiento del cáncer de próstata localizado | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/prostate-cancer-therapies-update/espanol
    December 06, 2016 - Examen de sangre para antígeno prostático específico (PSA, en inglés): Este análisis de sangre indica … cuánto PSA (una proteína elaborada por la próstata) circula en la sangre. … Un nivel alto de PSA no siempre significa que el hombre tenga cáncer de próstata. … Su médico puede utilizar su nivel de PSA, el puntaje de Gleason y el puntaje tumoral (puntaje T) para … El cáncer se descubre en una biopsia efectuada después que un hombre presenta un nivel alto de PSA o