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61. Prostate-Cancer-Therapies-Update Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_executive.pdf
    December 01, 2014 - Comparative Effectiveness Review Number 146 a physical examination, prostate-specific antigen (PSA … Effective Health Care Program 2 The PSA test is used to measure blood levels of PSA, a protein produced … separating a “normal” PSA level from an abnormal level also remains a subject of debate. … PSA, PSA kinetics (rate of rise in PSA over time and doubling time for PSA), and digital rectal examination … cancer (especially low PSA/low-risk disease, but possibly intermediate PSA/intermediate-risk disease

62. Prostate-Cancer-Therapies-Update Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_executive.pdf
    December 01, 2014 - Comparative Effectiveness Review Number 146 a physical examination, prostate-specific antigen (PSA … Effective Health Care Program 2 The PSA test is used to measure blood levels of PSA, a protein produced … separating a “normal” PSA level from an abnormal level also remains a subject of debate. … PSA, PSA kinetics (rate of rise in PSA over time and doubling time for PSA), and digital rectal examination … cancer (especially low PSA/low-risk disease, but possibly intermediate PSA/intermediate-risk disease

63. Therapies for Clinically Localized Prostate Cancer | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/prostate-cancer-therapies/report
    January 01, 2021 - to no mortality difference versus RP or external beam radiation (EBR)+androgen deprivation (AD) in PSA … Among clinically rather than prostate-specific antigen (PSA) detected CLPC, Watchful Waiting (WW) may … effect on mortality may vary by tumor risk and age but not by race, health status, comorbidities, or PSA … Active Monitoring (AM) probably results in little to no difference in mortality in PSA-detected CLPC … RCTs in PSA-detected and MRI staged CLPC are needed.

64. Localized Prostate Cancer | Effective Health Care
    effectivehealthcare.ahrq.gov/decision-aids/prostate-cancer/07.html
    June 08, 2018 - Your doctor will use your PSA level, Gleason Score, and tumor "T stage" to determine whether your cancer … Prostate Cancer Risk Groups Low Risk Low-risk cancer has PSA levels less than 10 ng/ml, Gleason … Intermediate/Medium Risk Medium-risk cancer has PSA levels of 10–20 ng/ml, Gleason Scores of 7, or … High Risk High-risk cancer has PSA levels of more than 20 ng/ml, Gleason Scores of 8 or higher, or

65. Psn-Pdf (pdf file)
    psnet.ahrq.gov/node/49871/psn-pdf
    August 10, 2019 - the patient was seen by a physician assistant who inquired about prior prostate specific antigen (PSA … According to the patient, when he answered that he had never had PSA testing, he was berated for not … work including a PSA test, scheduled a cystoscopy, and urged the patient to self-catheterize should … A PSA test is often ordered in this clinical situation but should not be performed without discussing … , PSA levels decrease about 50% on a 5-ARI, and a subsequent increase in an adherent patient may warn

66. PCA3 Testing for the Diagnosis and Management of Prostate Cancer | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/prostate-cancer-test/research
    December 01, 2019 - Comparators included total prostate specific antigen (PSA) elevations, free PSA, PSA density, PSA velocity … , externally validated nomograms, complexed PSA, and multivariate models. … Comparison of PCA3 to total PSA (tPSA) had the most available studies (22) but was subject to spectrum

67. Comparative Effectiveness of Drug Therapy for Psoriatic Arthritis in Adults – An Update to the 2007 Report | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/arthritis-psoriatric/research-protocol
    December 06, 2010 - PDF 729.3 KB Background and Objectives for the Systematic Review Psoriatic arthritis (PsA … PsA has a highly variable presentation, which generally involves pain and inflammation in joints and … Additionally, PsA may predate the development of skin disease leading to some diagnostic uncertainty. … In the general population the prevalence of PsA is estimated to be 0.3% to 1%. … Treatment of psoriatic arthritis (PsA) aims to control pain and inflammation and, ultimately, to slow

68. Prostate Cancer Screening Recommendation Frequently Asked Questions (pdf file)
    www.uspreventiveservicestaskforce.org/Home/GetFileByID/3786
    October 09, 2018 - How to interpret the recommendation What is the PSA test? … The PSA test measures the amount of prostate-specific antigen, a type of protein, in a man’s blood. … When a man has an elevated PSA level, it may be caused by prostate cancer, but it could also be caused … What’s the harm in getting a PSA test? … It includes regular, repeated PSA testing and often repeated digital rectal examination and prostate

69. Prostate Cancer Screening Recommendation Frequently Asked Questions (pdf file)
    www.uspreventiveservicestaskforce.org/Home/GetFileByToken/-BbKrbuLt9RAPvf3BQrUMW
    October 09, 2018 - How to interpret the recommendation What is the PSA test? … The PSA test measures the amount of prostate-specific antigen, a type of protein, in a man’s blood. … When a man has an elevated PSA level, it may be caused by prostate cancer, but it could also be caused … What’s the harm in getting a PSA test? … It includes regular, repeated PSA testing and often repeated digital rectal examination and prostate

70. Comparative Effectiveness of Therapies for Clinically Localized Prostate Cancer: An Update of a 2008 Comparative Effectiveness Review | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/prostate-cancer-therapies-update/research-protocol
    December 01, 2019 - The PSA test is used to measure blood levels of PSA, a protein produced by the prostate gland. 4 Elevated … ≤6   T1–2a N0 M0 PSA X Gleason X IIA T1a–c N0 M0 PSA<20 Gleason 7 …   T1a–c N0 M0 PSA≥10<20 Gleason ≤6   T2a N0 M0 PSA≥10<20 Gleason ≤6 …   T2a N0 M0 PSA<20 Gleason 7   T2b N0 M0 PSA<20 Gleason ≤7 IIB T2b … N0 M0 PSA X Gleason X   T2c N0 M0 Any PSA Any Gleason   T1–2 N0

71. Treating Localized Prostate Cancer | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/prostate-cancer-therapies-update/consumer
    January 21, 2016 - PSA blood test: This blood test tells how much PSA (a protein made by the prostate gland) is in your … Many men with prostate cancer have PSA levels that are higher than normal or that have gotten higher … A high PSA level does not always mean a man has prostate cancer. … This growth, and other health conditions, can cause a high PSA level in men who do not have prostate … Determining risk level Risk Level* PSA Level Gleason Score T-Score * From the 2015 clinical

72. Prostate-Cancer-Therapies-Update Consumer (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_consumer.pdf
    January 01, 2016 - � PSA blood test: This blood test tells how much PSA (a protein made by the prostate gland) is in … – A high PSA level does not always mean a man has prostate cancer. … This growth, and other health conditions, can cause a high PSA level in men who do not have prostate … Your doctor can use your PSA level, Gleason score, and tumor score (T-score) to determine your risk … The cancer is found from a biopsy done after a man has a high PSA level or has surgery for problems

73. Prostate-Cancer-Therapies-Update Consumer (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_consumer.pdf
    January 01, 2016 - � PSA blood test: This blood test tells how much PSA (a protein made by the prostate gland) is in … – A high PSA level does not always mean a man has prostate cancer. … This growth, and other health conditions, can cause a high PSA level in men who do not have prostate … Your doctor can use your PSA level, Gleason score, and tumor score (T-score) to determine your risk … The cancer is found from a biopsy done after a man has a high PSA level or has surgery for problems

74. Tx-For-Localized-Prostate-Cancer Surveillanceassesment 20120614 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/tx-for-localized-prostate-cancer_surveillanceassesment_20120614.pdf
    May 01, 2012 - However, a subgroup analysis suggested that men with high-risk features (PSA > 10, and intermediate … levels and Gleason histologic score (PSA >10 ng/ml or Gleason >6). … In men with PSA >10, radical prostatectomy reduced overall mortality (HR = 0.36, p=0.03). … In men with PSA >10, radical prostatectomy reduced overall mortality (HR = 0.36, p=0.03). … levels and Gleason histologic score (PSA >10 ng/ml or Gleason >6).

75. Tx-For-Localized-Prostate-Cancer Surveillanceassesment 20120614 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/tx-for-localized-prostate-cancer_surveillanceassesment_20120614.pdf
    May 01, 2012 - However, a subgroup analysis suggested that men with high-risk features (PSA > 10, and intermediate … levels and Gleason histologic score (PSA >10 ng/ml or Gleason >6). … In men with PSA >10, radical prostatectomy reduced overall mortality (HR = 0.36, p=0.03). … In men with PSA >10, radical prostatectomy reduced overall mortality (HR = 0.36, p=0.03). … levels and Gleason histologic score (PSA >10 ng/ml or Gleason >6).

76. Tx-For-Localized-Prostate-Cancer Surveillanceassesment 20120614 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/tx-for-localized-prostate-cancer_surveillanceassesment_20120614.pdf
    May 01, 2012 - However, a subgroup analysis suggested that men with high-risk features (PSA > 10, and intermediate … levels and Gleason histologic score (PSA >10 ng/ml or Gleason >6). … In men with PSA >10, radical prostatectomy reduced overall mortality (HR = 0.36, p=0.03). … In men with PSA >10, radical prostatectomy reduced overall mortality (HR = 0.36, p=0.03). … levels and Gleason histologic score (PSA >10 ng/ml or Gleason >6).

77. Tx-For-Localized-Prostate-Cancer Surveillanceassesment 20120614 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/tx-for-localized-prostate-cancer_surveillanceassesment_20120614.pdf
    May 01, 2012 - However, a subgroup analysis suggested that men with high-risk features (PSA > 10, and intermediate … levels and Gleason histologic score (PSA >10 ng/ml or Gleason >6). … In men with PSA >10, radical prostatectomy reduced overall mortality (HR = 0.36, p=0.03). … In men with PSA >10, radical prostatectomy reduced overall mortality (HR = 0.36, p=0.03). … levels and Gleason histologic score (PSA >10 ng/ml or Gleason >6).

78. U.S. Preventive Services Task Force Seeks Comments on Draft Recommendation Statement on Screening for Prostate Cancer (pdf file)
    www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/file/supporting_documents/prostate-cancer-draft-bulletin.pdf
    April 03, 2017 - For men ages 70 years and older, the potential benefits of PSA-based screening do not outweigh the … (D recommendation) Visit www.screeningforprostatecancer.org for more information The PSA test … When a man has an elevated PSA, it may be caused by prostate cancer, but it could also be caused by … PSA-based screening and follow-up prostate biopsies cannot tell for sure which cancers are likely to … based in part on new evidence on the use of active surveillance, which includes regular, repeated PSA

79. Therapies for Clinically Localized Prostate Cancer (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_clinician.pdf
    January 01, 2016 - convened in 2011 recommended that AS—a strategy with curative intent that involves regular monitoring of PSA … and then intervening to manage them.3 WW does not include active monitoring such as performing a PSA … Presenting symptoms, a physical examination, a prostate- specific antigen (PSA) test, and a biopsy may … by factors such as patient age and health at the time of diagnosis, life expectancy, tumor stage, PSA … Prostate cancer incidence and PSA testing patterns in relation to USPSTF screening recommendations.

80. Therapies for Clinically Localized Prostate Cancer (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_clinician.pdf
    January 01, 2016 - convened in 2011 recommended that AS—a strategy with curative intent that involves regular monitoring of PSA … and then intervening to manage them.3 WW does not include active monitoring such as performing a PSA … Presenting symptoms, a physical examination, a prostate- specific antigen (PSA) test, and a biopsy may … by factors such as patient age and health at the time of diagnosis, life expectancy, tumor stage, PSA … Prostate cancer incidence and PSA testing patterns in relation to USPSTF screening recommendations.