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121. NIH State-of-the-Science Conference: Role of Active Surveillance in the Management of Men With Localized Prostate Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/prostate-cancer-surveillance/research-protocol
     December 01, 2019 - Currently, most prostate cancer in men in the United States is found by prostate-specific antigen (PSA … Active surveillance is a fairly involved followup of patients—by monitoring PSA levels and sometimes … Comorbidity Race/ethnicity Tumor Characteristics Stage Tumor volume Gleason Score PSA … Common metrics Age Gleason Score Number of cores Percentage of cores PSA (velocity, doubling … node involvement (N0–X) or metastases (M0–X), regardless of age, histologic grade, Gleason Score, or PSA

122. Chartbook on Care Affordability: Slide Presentation | Agency for Healthcare Research and Quality
     www.ahrq.gov/research/findings/nhqrdr/chartbooks/careaffordability/careaffordability-slides.html
     September 01, 2018 - Services Task Force recommended against screening men age 75 and over with prostate-specific antigen (PSA … Overall Rate: In 2014, 21.1% of men age 40 and over reported a PSA test in the past year (data not shown … Groups With Disparities: In 2014, men ages 40-54 were less likely to receive a PSA test in the past … Among men ages 40-54, Asians were less likely than Whites to receive PSA testing and Blacks were more … Among men age 75 and over, AI/ANs were less likely than Whites to receive PSA testing.

123. Section 2. Recommendations for Adults (continued) | Agency for Healthcare Research and Quality
     www.ahrq.gov/prevention/guidelines/guide/section2c.html
     June 01, 2014 - Prostate Cancer Population Adult males Recommendation Do not use prostate-specific antigen (PSA … Contemporary recommendations for prostate cancer screening all incorporate the measurement of serum PSA … There is convincing evidence that PSA-based screening programs result in the detection of many cases … prostate cancer, and that a substantial percentage of men who have asymptomatic cancer detected by PSA … The benefits of PSA-based screening for prostate cancer do not outweigh the harms.

124. Disposition of Comments for Comparative Effectiveness of Therapies for Clinically Localized Prostate Cancer: An Update of a 2008 Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_disposition-comments.pdf
     December 16, 2014 - No organization (including the AUA) currently recommends PSA testing. … PIVOT conducted in the US and primarily involved men with PSA detected tumors. … SPCG-4 conducted in absence of PSA testing, had much higher CaP mortality rates. … target higher PSA/higher risk disease as CER or vs. … Page – 12, Line 28 – what constitutes a “normal” PSA is, in itself.

125. Disposition of Comments for Comparative Effectiveness of Therapies for Clinically Localized Prostate Cancer: An Update of a 2008 Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_disposition-comments.pdf
     December 16, 2014 - No organization (including the AUA) currently recommends PSA testing. … PIVOT conducted in the US and primarily involved men with PSA detected tumors. … SPCG-4 conducted in absence of PSA testing, had much higher CaP mortality rates. … target higher PSA/higher risk disease as CER or vs. … Page – 12, Line 28 – what constitutes a “normal” PSA is, in itself.

126. An Evidence Review of Active Surveillance in Men with Localized Prostate Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-surveillance_disposition-comments.pdf
     December 01, 2011 - Clinical staging in prostate cancer (based on DRE, Gleason score and PSA) is limited. … The reviewer suspects PSA thresholds to recommend biopsies have been dropping over the “PSA era”. … Prostate-specific antigen (PSA) kinetics in untreated, localized prostate cancer: PSA velocity vs PSA … PSA kinetics were assessed during followup; this has been clarified in the paragraph. … PSA density (PSAD) is also included in some (e.g., Hopkins).

127. An Evidence Review of Active Surveillance in Men with Localized Prostate Cancer (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/prostate-cancer-surveillance_disposition-comments.pdf
     December 01, 2011 - Clinical staging in prostate cancer (based on DRE, Gleason score and PSA) is limited. … The reviewer suspects PSA thresholds to recommend biopsies have been dropping over the “PSA era”. … Prostate-specific antigen (PSA) kinetics in untreated, localized prostate cancer: PSA velocity vs PSA … PSA kinetics were assessed during followup; this has been clarified in the paragraph. … PSA density (PSAD) is also included in some (e.g., Hopkins).

128. Psn-Pdf (pdf file)
     psnet.ahrq.gov/node/49632/psn-pdf
     July 01, 2011 - After discussion, the provider sent off a prostate-specific antigen (PSA) test to screen the patient … The patient's past PSA tests had always been normal. … Unfortunately, this time his PSA returned markedly elevated at 83 ng/ml—a level at which cancer is a … tests confirmed metastatic prostate cancer and also uncovered the missed follow-up of the elevated PSA … types of handoffs, the written sign-out should identify active issues, pending lab tests (such as the PSA

129. A Seasonal Care Transition Failure | PSNet
     psnet.ahrq.gov/web-mm/seasonal-care-transition-failure
     June 01, 2016 - After discussion, the provider sent off a prostate-specific antigen (PSA) test to screen the patient … The patient's past PSA tests had always been normal. … Unfortunately, this time his PSA returned markedly elevated at 83 ng/ml—a level at which cancer is a … tests confirmed metastatic prostate cancer and also uncovered the missed follow-up of the elevated PSA … types of handoffs, the written sign-out should identify active issues, pending lab tests (such as the PSA

130. Slide 1
     www.ahrq.gov/sites/default/files/wysiwyg/research/findings/nhqrdr/chartbooks/careaffordability/qdr2015-chartbook-careaffordability.pptx
     August 01, 2016 - Services Task Force recommended against screening men age 75 and over with prostate-specific antigen (PSA … Overall Rate: In 2014, 21.1% of men age 40 and over reported a PSA test in the past year (data not shown … Groups With Disparities: In 2014, men ages 40-54 were less likely to receive a PSA test in the past year … Among men ages 40-54, Asians were less likely than Whites to receive PSA testing and Blacks were more … Among men age 75 and over, AI/ANs were less likely than Whites to receive PSA testing.

131. Methods Guide for Medical Test Reviews Chapter 9 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-performance_methods.pdf
     July 01, 2012 - PSA levels have been used to detect the presence of prostate cancer, and over the years, a number of … different PSA detection methods have been developed. … results) is that obesity can reduce serum PSA levels. … not have elevated PSA by a new detection 9-8 method are also likely to not have elevated PSA by … In contrast, if the newer PSA detection method was compared to a non-PSA based reference standard that

132. Methods Guide for Medical Test Reviews Chapter 9 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-performance_methods.pdf
     July 01, 2012 - PSA levels have been used to detect the presence of prostate cancer, and over the years, a number of … different PSA detection methods have been developed. … results) is that obesity can reduce serum PSA levels. … not have elevated PSA by a new detection 9-8 method are also likely to not have elevated PSA by … In contrast, if the newer PSA detection method was compared to a non-PSA based reference standard that

133. Chapter 9: Options for Summarizing Medical Test Performance in the Absence of a “Gold Standard” | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-performance/methods
     December 01, 2019 - A clinically relevant example is the use of prostate-specific antigen (PSA) to detect prostate cancer … different PSA detection methods have been developed. … results) is that obesity can reduce serum PSA levels. … not have elevated PSA by a new detection method are also likely to not have elevated PSA by the older … In contrast, if the newer PSA detection method was compared to a non-PSA based reference standard that

134. Screening for Prostate Cancer: A Review of the Evidence for the U.S. Preventive Services Task Force (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/G9P7o8jDh4J3NnAk6y-SYL
     December 01, 2011 - What are the harms of PSA-based screening for prostate cancer? … of trial participants had under- gone PSA screening before entry. … One trial used a high PSA cut point (10 �g/L) (16). … group (50% received �1 PSA test). … What are the harms of PSA-based screening for prostate cancer?

135. Psn-Pdf (pdf file)
     psnet.ahrq.gov/node/33875/psn-pdf
     March 01, 2019 - This practice called professional services agreements, or PSA, where an individual or a group of physicians … The range of system expansion can be from a single PSA physician that's independent of any bigger whole … This PSA [professional services agreement] thing is just enormous. … We (Ariadne) are working through the PSA process for surgery. … We have developed a list of questions that a PSA surgeon would want to know going to a new hospital

136. Psn-Pdf (pdf file)
     psnet.ahrq.gov/node/49556/psn-pdf
     March 01, 2008 - Available at: http://www.psa.state.pa.us/psa/lib/psa/advisories/mar_2006_advisory_v3_n1.pdf. 2. … View AHRQ Disclaimers http://www.psa.state.pa.us/psa/lib/psa/advisories/mar_2006_advisory_v3_n1.pdf

137. Published Projects | SRDR
     srdrplus.ahrq.gov/published_projects?page=20
     June 27, 2021 - Among clinically, rather than PSA detected CLPC, WW may increase overall and prostate-cancer mortality … on mortality may have varied by tumor risk and age but not by race, health status, comorbidities or PSA … AM probably results in little to no difference in overall or prostate-cancer mortality in PSA detected … Large, long-term RCTs in PSA-detected and MRI staged CLPC are needed.

138. 2015 National Healthcare Quality and Disparities Report: Chartbook on Care Affordability (pdf file)
     www.ahrq.gov/sites/default/files/wysiwyg/research/findings/nhqrdr/chartbooks/careaffordability/qdr2015-chartbook-careaffordability.pdf
     August 01, 2016 -  Overall Rate: In 2014, 21.1% of men age 40 and over reported a PSA test in the past year (data …  Groups With Disparities: ■ In 2014, men ages 40-54 were less likely to receive a PSA test in the … ■ Among men ages 40-54, Asians were less likely than Whites to receive PSA testing and Blacks were … , Asians, and American Indians and Alaska Natives (AI/ANs) were less likely than Whites to receive PSA … ■ Among men age 75 and over, AI/ANs were less likely than Whites to receive PSA testing.

139. Percentage of Verbal Orders (pdf file)
     digital.ahrq.gov/sites/default/files/docs/page/percentage-of-verbal-orders-quick-reference-guide.pdf
     March 01, 2009 - http://www.psa.state.pa.us/psa/lib/psa/advisories /v3n2june2006/junevol 3 no 2 article b safety of

140. Prevention is Key to a Healthy America (pdf file)
     www.ahrq.gov/sites/default/files/wysiwyg/professionals/prevention-chronic-care/decision/research-centers/RCInfographic.pdf
     September 01, 2010 - men had unneeded prostate cancer treatment after PSA testing was introduced.3 950,000+ Health