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41. Disposition of Comments Report for Multigene Panels in Prostate Cancer Risk Assessment (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_disposition-comments.pdf
    July 03, 2012 - How do available panels predict the risk of prostate cancer when substituted for, or added to, PSA based … benefit to a patient for using a particular decision rule to opt for a prostate biopsy or perhaps PSA … screening, specifically, by choosing a threshold risk and deciding to undergo biopsy or PSA screening

42. Prostate-Cancer-Risk-Assessment-Genes Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_executive.pdf
    July 01, 2012 - Prostate-specific antigen (PSA) was approved by the US Food and Drug Administration in 1986 for monitoring … screening asymptomatic men).14 A meta- analysis of seven randomized controlled trials of screening using PSA … How do SNP-based strategies (alone or in combination with PSA) compare with current practice? … cancer mortality for any of the panels,47,55,59 and no increase in the AUC of a model based on age, PSA … Meta-analysis finds screening for prostate cancer with PSA does not reduce prostate cancer-related

43. Assessing the Applicability of Studies When Comparing Medical Interventions | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/methods-guidance-applicability/methods
    May 01, 2020 - Cancer registries in the United States indicate that most localized cancers are detected by PSA testing … A2 (SPCG-4) 1989-1999, Sweden Mean age 65 78% T2; 60% Gleason 6 or lower Few detected by PSA … 1967-1975, Denmark Mean age 64.2 46.5% Stage 2; 86.5% Gleason 6 or lower None detected by PSA … to current practices due to the evolving techniques in both stage and grade classification since PSA … the largest group of prostate cancer patients in the United States, those with cancers detected by PSA

44. Methods-Guidance-Applicability Methods (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-applicability_methods.pdf
    January 01, 2011 - Cancer registries in the United States indicate that most localized cancers are detected by PSA testing … Few detected by PSA Radical prostatectomy at 18 centers; standard current protocol Watchful … None detected by PSA. … to current practices due to the evolving techniques in both stage and grade classification since PSA … the largest group of prostate cancer patients in the United States, those with cancers detected by PSA

45. Methods Guide Atkins (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/methods_guide_atkins.pdf
    January 01, 2011 - Cancer registries in the United States indicate that most localized cancers are detected by PSA testing … Few detected by PSA Radical prostatectomy at 18 centers; standard current protocol Watchful … None detected by PSA. … to current practices due to the evolving techniques in both stage and grade classification since PSA … the largest group of prostate cancer patients in the United States, those with cancers detected by PSA

46. Comparative Effectiveness of Drug Therapy for Rheumatoid Arthritis and Psoriatic Arthritis in Adults | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/rheumatoid-arthritis-2007/research
    December 01, 2019 - biologic DMARDs in the treatment of patients with either rheumatoid arthritis (RA) or psoriatic arthritis (PsA

47. Prostate Cancer | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/health-topics/prostate-cancer
    September 17, 2020 - You may also get a blood test for prostate-specific antigen (PSA).

48. Disposition of Comments: CER 230 Therapies for Clinically Localized Prostate Cancer (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-230-prostate-cancer-comments.pdf
    September 17, 2020 - • The reviewers repeatedly emphasized the distinction between mostly PSA-based active monitoring

49. Evidence-based Practice Center Systematic Review Protocol: Therapies for Clinically Localized Prostate Cancer (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-protocol_amended110619.pdf
    November 02, 2019 - , or ablated.3, 4 Instead, tumors are monitored through surveillance of prostate specific antigen (PSA … patient characteristics (e.g., age, ethnicity, comorbidities, preferences), tumor characteristics (e.g., PSA … 1) Baseline PSA 2) Gleason score 3) Tumor index scores (e.g., Cancer of the Prostate Risk Assessment … hormone-releasing hormone MRI= magnetic resonance imaging NCCN= National Comprehensive Cancer Network PSA

50. Therapies for Clinically Localized Prostate Cancer | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/prostate-cancer-therapies/protocol
    March 01, 2020 - or ablated. 3 , 4 Instead, tumors are monitored through surveillance of prostate specific antigen (PSA … patient characteristics (e.g., age, ethnicity, comorbidities, preferences), tumor characteristics (e.g., PSA … Baseline PSA Gleason score Tumor index scores (e.g., Cancer of the Prostate Risk Assessment Score … hormone-releasing hormone MRI= magnetic resonance imaging NCCN= National Comprehensive Cancer Network PSA

51. Primary Hypofractionated Radiation Therapy for Localized Prostate Cancer: Research Protocol (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-protocol.pdf
    April 17, 2024 - These include reduced access to prostate-specific antigen-based (PSA) screening and high- quality prostate … Racial and Ethnic Variation in PSA Testing and Prostate Cancer Incidence Following the 2012 USPSTF Recommendation … treated by external beam radiation therapy alone using a post-treatment repeated-measures model for PSA … recurrence-free survival: The length of time after treatment during which a patient has no evidence of rising PSA

52. Braddock (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/braddock.pdf
    January 01, 2011 - decision-­‐making o Fewer people remaining  undecided o Fewer patients choosing  major surgery, PSA

53. Can screening among the general adult male population for elevated PCA3 (also known as DD3) gene expression, to identify those at risk for prostate cancer who may be candidates for prostate biopsy, reduce morbidity and mortality? | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/can-screening-among-the-general-adult-male-population-for-elevated-pca3-also-known-as-dd3-gene-expression-to-identify-those-at-risk-for-prostate-cancer-who-may-be-candidates-for-prostate-biopsy-reduce-morbidity-and-mortality
    November 01, 2017 - commercially available PCA3 expression assays for prostate cancer screening tests vs. screening by PSA

54. Moyer_ECCS2012 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/moyer_eccs2012.pdf
    January 01, 2012 - of Pediatrics Baylor College of Medicine,  Houston,  TX Slide 2: A Recent Controversy “Those PSA

55. Primary Hypofractionated Radiation Therapy for Localized Prostate Cancer: A Systematic Review | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/hypofractionated-radiation-therapy/protocol
    December 01, 2024 - These include reduced access to prostate-specific antigen-based (PSA) screening and high-quality prostate … Racial and Ethnic Variation in PSA Testing and Prostate Cancer Incidence Following the 2012 USPSTF Recommendation … treated by external beam radiation therapy alone using a post-treatment repeated-measures model for PSA … recurrence-free survival : The length of time after treatment during which a patient has no evidence of rising PSA

56. Psoriasis-Chronic Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_executive.pdf
    November 01, 2012 - However, there was insufficient evidence to grade HRQoL, BSA, PASI, PGA, psoriatic arthritis (PsA) … Two observational studies25,27 evaluated the impact of weight on PGA, the impact of a history of PsA … on plaque psoriasis or PsA pain, and the impact of prior exposure to a biologic agent on PASI. … Index PCS Physical Component Summary (part of SF-36) PGA Physician’s Global Assessment PsA

57. Schwitzer_ECCS2012 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/schwitzer_eccs2012.pdf
    July 23, 2012 - emeritus of family medicine at Brown University School of Medicine, tells his physician not to order a PSA

58. THIS IS OUR TEACHER! (ppt file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/communicating_risk_media_wilkes.ppt
    April 01, 2006 - surgical implants when a similar operation without implants works better; Doctors order diagnostic tests (PSA

59. Disposition of Comments Report for Decision Aids for Cancer Screening and Treatment (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-decision-support-tools_disposition-comments.pdf
    December 23, 2014 - concerned the review missed 2 previous reviews which each found decision aids decreased uptake of PSA … TEP Reviewer #4 Results P. 23 Cochrane systematic review of decision aids has subgruop analysis on PSA … We did not undertake a subgroup analysis specific to PSA testing.

60. Methods Guide for Medical Test Reviews Chapter 7 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-grading_methods.pdf
    July 01, 2012 - some tests that have continuous outcomes and possibly multiple cutoffs [e.g., gene expression, serum PSA … some tests that have continuous outcomes and possibly multiple cutoffs (e.g., gene expression, serum PSA