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421. 8 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
     November 01, 2008 - They provide syntheses of relevant evidence to inform real-world health care decisions for patients, … ―Head-to-head‖ RCTs provide the most direct evidence on comparative harms. … However, placebo-controlled RCTs may also provide important information on absolute and relative risks … In addition, placebo-controlled trials can provide information about risks that may not be apparent … In drug trials, use of an independent external endpoint committee may provide less biased estimates

422. Research White Paper Multinational Registries Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/multinational-registries-guide-3rd-ed-addendum-white-paper.pdf
     February 01, 2018 - European Medicines Agency (EMA) are nearly always multinational, so that the registry will be able to provide … 1 Multinational Registries: Challenges and Opportunities Multinational registries can also provide … of the User’s Guide12), once accomplished, linkage may reduce the data entry burden on sites and/or provide … The purpose of the following sections is solely to provide information that will help readers understand … the issues relevant to conducting multinational registries; this section is not intended to provide

423. Methods Guide for Comparative Effectiveness Reviews - Avoiding Bias in Selecting Studies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
     February 01, 2013 - The reports and assessments provide organizations with comprehensive, science-based information on common … Gray literature helps to provide some fuzzy information on areas that were previously a blind spot in … Nonetheless, they can provide data and analyses of Phase 2 and 3 trials that may be more extensive than … For unpublished studies, manufacturers are asked to provide a summary that includes study number, study … Gray literature can provide evidence on publication bias and outcomes reporting bias; EPCs should use

424. Prostate-Cancer-Therapies-Update Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_research-protocol.pdf
     April 01, 2013 - Additionally, many of these RCTs were inadequately powered to provide long-term survival outcomes, with … Trials must focus on, or provide separate analyses for, subjects with localized disease (T1/T2). … Did 85 percent or more of enrolled patients provide data at the time point of interest? — 7. … Rating the Strength of the Body of Evidence We plan to provide evidence ratings (see Table 13) for … Peer Reviewers Peer Reviewers are invited to provide written comments on the draft report based on

425. Back-Pain-Imaging Clinician (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-imaging_clinician.pdf
     April 01, 2016 - The findings from this study provide evidence that aligns with the guidelines from the American College … Taking a careful medical history and performing a thor- ough physical examination provide all the information

426. ambulatory-safety-protocol-150724 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ambulatory-safety_research-protocol.pdf
     July 24, 2015 - We will ask the Key Informants to provide references for any studies they believe would be relevant. … Peer Reviewers Peer reviewers are invited to provide written comments on the draft report based on their

427. First- and Second-Generation Antipsychotics in Children and Young Adults: Systematic Review Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update-disposition-170621.pdf
     March 16, 2017 - Commentators are not required to provide their names or affiliations in order to submit suggestions … Did the studies provide adjusted estimates for effect size? … TEP 7 Methods [page 67]: Provide reference for interpretation of inconsistency factor plots, as these … We have added a sentence for how people can interpret these, “Bayesian approaches provide variances … In this case, find the probability of “worst”, which may provide more useful information.

428. First- and Second-Generation Antipsychotics in Children and Young Adults: Systematic Review Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-update-disposition-170621.pdf
     March 16, 2017 - Commentators are not required to provide their names or affiliations in order to submit suggestions … Did the studies provide adjusted estimates for effect size? … TEP 7 Methods [page 67]: Provide reference for interpretation of inconsistency factor plots, as these … We have added a sentence for how people can interpret these, “Bayesian approaches provide variances … In this case, find the probability of “worst”, which may provide more useful information.

429. Research Protocol: Improving Cultural Competence To Reduce Health Disparities for Priority Populations (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cultural-competence_research-protocol.pdf
     July 09, 2014 - • Cultural competence interventions that improve the ability of providers to provide health care … The following matrixes provide a basic framework by which intervention population targets and general … Results and risk of bias will be presented for other reported included studies to provide information … Within the EPC program, the Key Informant role is to provide input into identifying the Key Questions … They are selected to provide broad expertise and perspectives specific to the topic under development

430. Implementing Evidence-Based Screening and Counseling for Unhealthy Alcohol-Use With Epic-Based Electronic Health Record Tools: A Guide for Clinics and Health Systems Developed as Part of a Pilot Dissemination Project (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/implementation-package-unhealthy-alcohol-use-final.pdf
     September 01, 2018 - The reports and assessments provide organizations with comprehensive, science-based information on common … Our team also sought to increase buy-in and to provide positive reinforcement with acknowledgment of … What intervention should you provide for Mrs. Skyy? … What information regarding safe drinking levels and health risks would you provide him with? … You provide him with a drinking diary which is located in all the exam rooms (“Rethinking Drinking”

431. Disposition of Comments for Technical Brief 29 Women Living With HIV-AIDS (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/women-hiv_disposition-comments.pdf
     November 21, 2016 - Commentators are not required to provide their names or affiliations in order to submit suggestions … result reflects a bit of a mismatch between the mission of a technical brief (“It is intended to provide … • Focus on programs which provide primary medical care and psychosocial services to women, as well … Public Reviewer #2 (Laura Cheever) Findings Provide reasons why these articles have not yet been … Public Reviewer #2 (Laura Cheever) Summary and Implications Please provide a citation.

432. Disposition of Comments for CER 166 Calcineurin Inhibitors (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/calcineurin-inhibitor_disposition-comments.pdf
     March 15, 2016 - Commentators are not required to provide their names or affiliations in order to submit suggestions … other reviewers, we have expanded our discussion of the evidence addressing these questions to provide … We have revised the Discussion and Conclusion to provide a more valuable summary of our findings. … At Astellas, we recognize the need to provide comprehensive, evidence-based reviews that are relevant … However, it is important to note that external quality assessment (EQA) schemes that provide insight

433. Use of a Clinical Pathway To Facilitate the Translation and Utilization of AHRQ EPC Report Findings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/clinical-pathway-methods-report.pdf
     December 01, 2018 - The reports and assessments provide organizations with comprehensive, science-based information on common … The platform also provides a means for pathway users to provide instant electronic feedback to clinical … [8] Imaging: The IDSA doesn't provide guidance on imaging. Should we recommend imaging? … If so, please provide responses to the following questions regarding imaging types A and B below: … [9] Follow up during initiate episode treatment: The IDSA does not provide guidance -- Should we keep

434. Research White Paper Patient- or Participant-Generated Registries Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/patient-participant-generated-registries-guide-3rd-ed-addendum-white-paper.pdf
     February 01, 2018 - 16 iv Patient- or Participant-Generated Registries Introduction Patient registries can provide … PGRs can provide an opportunity for participants building on one another’s experiences to measure what … In addition, for those not taking such a committed step, they might provide input before, during, and … Fox Foundation’s Fox Trial Finder,49 provide potential trial participants with curated lists of clinical … The increase in the use of mobile health applications may soon provide a rich source of objective data

435. Disposition of Comments Report for The Patient-Centered Medical Home (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-centered-medical-home_disposition-comments.pdf
     July 03, 2012 - Commentators are not required to provide their names or affiliations in order to submit suggestions … Peer Reviewer 9 Results - p. 24, line 9/10: Provide additional details on how self-reported coordination … As project officer for the CMS evaluations, I also would be happy to provide additional details if … We recognize that there may be several ongoing PCMH demonstration projects that will provide useful … The review concluded that there was “moderate support for the hypothesis that medical homes provide

436. Disposition of Comments Report for CER 207 on PTSD (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-207-ptsd-disposition-comments.pdf
     May 17, 2018 - Commentators are not required to provide their names or affiliations in order to submit suggestions … However, for example, drop out after randomization may SOE would not provide evidence of a “bad apple … Clearly one laudable goal here is to provide the evidence-base for clinical decision-making in this … Appendix G does provide a qualitative assessment of what the high ROB studies show, compared to what … Please provide at least a brief discussion on this matter.

437. Disposition of Comments for Evidence Report 221 Behavioral Programs for Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_disposition-comments.pdf
     September 28, 2015 - Commentators are not required to provide their names or affiliations in order to submit suggestions … However, the investigators need to provide more information on model specifications. … Please provide an appendix to show the model formulation and the WinBUGs codes to fit the model. … They are designed to provide ongoing support. … We appreciate your comment and time taken to review and provide comments on the report.

438. Intravascular Diagnostic Procedures and Imaging Techniques Versus Angiography Alone in Coronary Stenting: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-stenting-future_research.pdf
     January 01, 2014 - The reports and assessments provide organizations with comprehensive, science-based information on common … Stakeholders were also encouraged to provide comments and feedback by email. … this would provide data for comparative analyses of patients who had FFR versus those who had not. … Randomized Controlled Trials Value of Study Design RCTs provide the most rigorous study design for … Randomized Controlled Trials Value of Study Design RCTs provide the most rigorous study design for

439. A Systematic Review of Postpartum Home Blood Pressure Monitoring, Postpartum Treatment of Hypertensive Disorders of Pregnancy, and Peripartum Magnesium Sulfate Regimens for Preeclampsia With Severe Features (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/hypertensive-disorders-pregnancy-protocol-amendment.pdf
     April 20, 2022 - Within the EPC program, the KIs’ role is to provide input into refining the Key Questions for research … The Technical Expert Panel is selected to provide broad expertise and perspectives specific to the topic … Technical Experts provide further input to finalize the KQs, study eligibility criteria, and analysis … The Technical Experts provide feedback on the full protocol. … They provide information to the EPC to identify literature search strategies and suggest approaches

440. Methods-Guidance-Reporting-Bias Methods (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-reporting-bias_methods.pdf
     November 01, 2013 - The reports and assessments provide organizations with comprehensive, science-based information on common … We discuss when those sources are likely to provide useful evidence and provide guidance on when searches … Contacting authors might also provide additional information regarding study methods that may prove … For specific data, such as a missing standard deviation, the review team may want to provide a brief … For observational studies we provide distinct recommendations.